Published in J Chromatogr on July 11, 1986
Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes. Proc Natl Acad Sci U S A (2007) 2.11
Current status of the polyamine research field. Methods Mol Biol (2011) 1.33
A randomized, double-blind, placebo-controlled phase 3 skin cancer prevention study of {alpha}-difluoromethylornithine in subjects with previous history of skin cancer. Cancer Prev Res (Phila) (2010) 1.21
Nuclear localization of human spermine oxidase isoforms - possible implications in drug response and disease etiology. FEBS J (2008) 1.08
Polyamine-regulated unproductive splicing and translation of spermidine/spermine N1-acetyltransferase. RNA (2006) 1.07
A small molecule polyamine oxidase inhibitor blocks androgen-induced oxidative stress and delays prostate cancer progression in the transgenic adenocarcinoma of the mouse prostate model. Cancer Res (2009) 1.06
Polyamine analogs modulate gene expression by inhibiting lysine-specific demethylase 1 (LSD1) and altering chromatin structure in human breast cancer cells. Amino Acids (2011) 1.03
Prostanoids, ornithine decarboxylase, and polyamines in primary chemoprevention of familial adenomatous polyposis. Gastroenterology (2004) 1.01
Polyamine biosynthesis impacts cellular folate requirements necessary to maintain S-adenosylmethionine and nucleotide pools. FASEB J (2009) 1.01
Rapid induction of apoptosis by deregulated uptake of polyamine analogues. Biochem J (1997) 0.95
Polyamine catabolism is enhanced after traumatic brain injury. J Neurotrauma (2010) 0.92
A new model for disruption of the ornithine decarboxylase gene, SPE1, in Saccharomyces cerevisiae exhibits growth arrest and genetic instability at the MAT locus. Biochem J (1995) 0.91
In vitro and in vivo effects of the conformationally restricted polyamine analogue CGC-11047 on small cell and non-small cell lung cancer cells. Cancer Chemother Pharmacol (2008) 0.90
Inhibition of calcium signalling in murine splenocytes by polyamines: differential effects on CD4 and CD8 T-cells. Biochem J (1993) 0.89
Unusual central nervous system toxicity in a phase I study of N1N11 diethylnorspermine in patients with advanced malignancy. Invest New Drugs (1997) 0.89
Combined regulation of ornithine and S-adenosylmethionine decarboxylases by spermine and the spermine analogue N1 N12-bis(ethyl)spermine. Biochem J (1990) 0.88
Lipophilic lysine-spermine conjugates are potent polyamine transport inhibitors for use in combination with a polyamine biosynthesis inhibitor. J Med Chem (2009) 0.88
Effect of polyamine depletion on chromatin structure in U-87 MG human brain tumour cells. Biochem J (1992) 0.86
Regulation of the efflux of putrescine and cadaverine from rapidly growing cultured RAW 264 cells by extracellular putrescine. Biochem J (1995) 0.86
Acute hypoxia increases ornithine decarboxylase activity and polyamine concentrations in fetal rat brain. Proc Natl Acad Sci U S A (1993) 0.85
Oligoamine analogues in combination with 2-difluoromethylornithine synergistically induce re-expression of aberrantly silenced tumour-suppressor genes. Biochem J (2012) 0.85
Norspermidine is not a self-produced trigger for biofilm disassembly. Cell (2014) 0.83
Caenorhabditis elegans P5B-type ATPase CATP-5 operates in polyamine transport and is crucial for norspermidine-mediated suppression of RNA interference. FASEB J (2009) 0.82
The re-expression of the epigenetically silenced e-cadherin gene by a polyamine analogue lysine-specific demethylase-1 (LSD1) inhibitor in human acute myeloid leukemia cell lines. Amino Acids (2013) 0.82
Self-immolative nanoparticles for simultaneous delivery of microRNA and targeting of polyamine metabolism in combination cancer therapy. J Control Release (2016) 0.81
Spermidine/spermine N1-acetyltransferase (SSAT) activity in human small-cell lung carcinoma cells following transfection with a genomic SSAT construct. Biochem J (2003) 0.81
The structure of polyamine analogues determines haemoglobin production and cytotoxicity in murine erythroleukaemia cells. Biochem J (1995) 0.80
Histone deacetylase inhibition overcomes drug resistance through a miRNA-dependent mechanism. Mol Cancer Ther (2013) 0.80
Spermine induces haemoglobin synthesis in murine erythroleukaemia cells. Biochem J (1995) 0.80
Phase I trial of the polyamine analog N1,N14-diethylhomospermine (DEHSPM) in patients with advanced solid tumors. Invest New Drugs (2004) 0.79
Self-immolative polycations as gene delivery vectors and prodrugs targeting polyamine metabolism in cancer. Mol Pharm (2014) 0.79
Downregulation of the polyamine regulator spermidine/spermine N(1)-acetyltransferase by Epstein-Barr virus in a Burkitt's lymphoma cell line. Virus Res (2013) 0.77
Knockdown of ornithine decarboxylase antizyme 1 causes loss of uptake regulation leading to increased N1, N11-bis(ethyl)norspermine (BENSpm) accumulation and toxicity in NCI H157 lung cancer cells. Amino Acids (2011) 0.77
Epigenetic silencing of miR-124 prevents spermine oxidase regulation: implications for Helicobacter pylori-induced gastric cancer. Oncogene (2016) 0.77
Spermine uptake is necessary to induce haemoglobin synthesis in murine erythroleukaemia cells. Biochem J (1995) 0.77
Spermine analogue-regulated expression of spermidine/spermine N1-acetyltransferase and its effects on depletion of intracellular polyamine pools in mouse fetal fibroblasts. Biochem J (2009) 0.77
Presence of N-acyl and acetoxy derivatives of putrescine and cadaverine in the human gut. Gut (1993) 0.76
Beneficial effects of a polyamine biosynthesis inhibitor on lupus in MRL-lpr/lpr mice. Clin Exp Immunol (1989) 0.76
Complex N-acetylation of triethylenetetramine. Drug Metab Dispos (2011) 0.76
Biochemical evaluation of the anticancer potential of the polyamine-based nanocarrier Nano11047. PLoS One (2017) 0.75
Role of ornithine decarboxylase/polyamine pathway in focal cerebral ischemia-reperfusion injury and its mechanism in rats. Int J Clin Exp Med (2015) 0.75
Alterations of chromosome arms 1p and 19q as predictors of survival in oligodendrogliomas, astrocytomas, and mixed oligoastrocytomas. J Clin Oncol (2000) 3.61
Imaging of dopamine transporters in humans with technetium-99m TRODAT-1. Eur J Nucl Med (1996) 2.91
Interaction of the AMPA receptor subunit GluR2/3 with PDZ domains regulates hippocampal long-term depression. Proc Natl Acad Sci U S A (2001) 2.75
Linkage analysis with multiplexed short tandem repeat polymorphisms using infrared fluorescence and M13 tailed primers. Genomics (1995) 2.36
Self-recognition of CD1 by gamma/delta T cells: implications for innate immunity. J Exp Med (2000) 2.30
Hydrocele of the canal of Nuck in a girl: ultrasound and MR appearance. Br J Radiol (2004) 2.26
Early Canadian chiropractic colleges. Chiropr Hist (1997) 2.19
Involvement of a postsynaptic protein kinase A substrate in the expression of homosynaptic long-term depression. Neuron (1998) 2.15
Technical and tumor-related factors affecting outcome of definitive irradiation for localized carcinoma of the prostate. Int J Radiat Oncol Biol Phys (1993) 2.04
Global public health and the information superhighway. Global health network university proposed. BMJ (1994) 2.03
Co-regulation of long-term potentiation and experience-dependent synaptic plasticity in visual cortex by age and experience. Nature (1995) 1.95
Sequential inactivation of rdxA (HP0954) and frxA (HP0642) nitroreductase genes causes moderate and high-level metronidazole resistance in Helicobacter pylori. J Bacteriol (2000) 1.77
Type 2 diabetes-associated genetic variants discovered in the recent genome-wide association studies are related to gestational diabetes mellitus in the Korean population. Diabetologia (2008) 1.67
MUC1, MUC2, MUC5AC, and MUC6 expressions in gastric carcinomas: their roles as prognostic indicators. Cancer (2001) 1.65
Determination of functional domains in polypyrimidine-tract-binding protein. Biochem J (1998) 1.63
Regulation of ion channels in smooth muscles by calcium. Am J Physiol (1996) 1.63
Ornithine decarboxylase is important in intestinal mucosal maturation and recovery from injury in rats. Science (1980) 1.61
A molecular genome scan analysis to identify chromosomal regions influencing economic traits in the pig. II. Meat and muscle composition. Mamm Genome (2001) 1.56
Spinal epidural extraskeletal Ewing sarcoma: MR findings in two cases. AJNR Am J Neuroradiol (2001) 1.53
Preoperative transarterial embolization of spinal tumor: embolization techniques and results. AJNR Am J Neuroradiol (2000) 1.53
Common promoter polymorphism in monocyte differentiation antigen CD14 is associated with serum triglyceride levels and body mass index in non-diabetic individuals. Diabet Med (2006) 1.52
Peripheral blood mitochondrial DNA content is related to insulin sensitivity in offspring of type 2 diabetic patients. Diabetes Care (2001) 1.49
Antitumor agents. Part 204: synthesis and biological evaluation of substituted 2-aryl quinazolinones. Bioorg Med Chem Lett (2001) 1.48
Frequent somatic mutations of the beta-catenin gene in intestinal-type gastric cancer. Cancer Res (1999) 1.47
Molecular mechanics of the interactions of spermine with DNA: DNA bending as a result of ligand binding. Nucleic Acids Res (1990) 1.46
Prevalence, awareness, treatment, control and risk factors of hypertension in Korea: the Ansan study. J Hypertens (2001) 1.46
Intracellular coexistence of methano- and thioautotrophic bacteria in a hydrothermal vent mussel. Proc Natl Acad Sci U S A (1995) 1.45
A rural-urban comparison of the characteristics of the metabolic syndrome by gender in Korea: the Korean Health and Genome Study (KHGS). J Endocrinol Invest (2006) 1.44
Implications and concepts of polyamine-nucleic acid interactions. J Cell Biochem (1991) 1.41
A transcript map of the chromosome 19q-arm glioma tumor suppressor region. Genomics (2000) 1.39
Insulin-dependent diabetes mellitus and rainfall. Lancet (1993) 1.39
Localized proton MR spectroscopy of the allocortex and isocortex in healthy children. AJNR Am J Neuroradiol (2000) 1.39
Spinal epidural cavernous hemangioma: MR findings. J Comput Assist Tomogr (2001) 1.38
Polyamines: a high correlation with cell replication. FEBS Lett (1975) 1.36
Spermine-DNA interactions: a theoretical study. Proc Natl Acad Sci U S A (1986) 1.36
Spinal intradural capillary hemangioma: MR findings. AJNR Am J Neuroradiol (2000) 1.35
A molecular genome scan analysis to identify chromosomal regions influencing economic traits in the pig. I. Growth and body composition. Mamm Genome (2001) 1.34
Risk factors for the development of NIDDM in Yonchon County, Korea. Diabetes Care (1997) 1.33
Nongenomic stimulation of nitric oxide release by estrogen is mediated by estrogen receptor alpha localized in caveolae. Biochem Biophys Res Commun (1999) 1.32
EHD2, EHD3, and EHD4 encode novel members of a highly conserved family of EH domain-containing proteins. Genomics (2000) 1.31
CT and MR imaging of head and neck tuberculosis. Radiographics (1997) 1.30
Salivary gland tumors: evaluation with two-phase helical CT. Radiology (2000) 1.29
Expression of Fas and Fas-related molecules in human hepatocellular carcinoma. Hum Pathol (2001) 1.27
A mitochondrial DNA variant at position 16189 is associated with type 2 diabetes mellitus in Asians. Diabetologia (2008) 1.24
Prevalence of the metabolic syndrome among South Korean adults: the Ansan study. Diabet Med (2004) 1.22
Somatic mutations of Fas (Apo-1/CD95) gene in cutaneous squamous cell carcinoma arising from a burn scar. J Invest Dermatol (2000) 1.21
Somatic mutations of the trefoil factor family 1 gene in gastric cancer. Gastroenterology (2000) 1.21
Factors influencing the survival of rat brain tumor cells after in vitro treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea. Cancer Res (1975) 1.21
Correlation between 99mTc-pertechnetate uptakes and expressions of human sodium iodide symporter gene in breast tumor tissues. Nucl Med Biol (2001) 1.20
Coronary heart disease mortality trends in men in the post World War II birth cohorts aged 35-44 in Japan, South Korea and Taiwan compared with the United States. Int J Epidemiol (1999) 1.17
Family planning practice and related factors of married women in Ethiopia. Int Nurs Rev (2010) 1.16
Effects of variation in the structure of spermine on the association with DNA and the induction of DNA conformational changes. Biochem J (1990) 1.14
Cyclin D1 overexpression in hepatocellular carcinoma. Liver (2001) 1.14
More sensitive automated detection of polyamines in physiological fluids and tissue extracts with omicron-phthalaldehyde. Clin Chem (1975) 1.13
Alterations of the DR5/TRAIL receptor 2 gene in non-small cell lung cancers. Cancer Res (1999) 1.12
Conformationally restricted analogues of 1N,12N-bisethylspermine: synthesis and growth inhibitory effects on human tumor cell lines. J Med Chem (1998) 1.10
A strong association between thyrotropin receptor-blocking antibody-positive atrophic autoimmune thyroiditis and HLA-DR8 and HLA-DQB1*0302 in Koreans. J Clin Endocrinol Metab (1993) 1.10
Measurement of bilirubin and its monoconjugates and diconjugates in human serum by alkaline methanolysis and high-performance liquid chromatography. J Lab Clin Med (1980) 1.10
Molecular dynamics of spermine-DNA interactions: sequence specificity and DNA bending for a simple ligand. Nucleic Acids Res (1989) 1.09
Vascular endothelial growth factor in patients with acute asthma. J Allergy Clin Immunol (2001) 1.08
Transluminal angioplasty for middle cerebral artery stenosis in patients with acute ischemic stroke. AJNR Am J Neuroradiol (1999) 1.08
Cosegregation of the renin allele of the spontaneously hypertensive rat with an increase in blood pressure. J Clin Invest (1990) 1.08
Simultaneous superficial hyperthermia and external radiotherapy: report of thermal dosimetry and tolerance to treatment. Int J Hyperthermia (1999) 1.08
Polyamines are necessary for the survival of human small-cell lung carcinoma in culture. Proc Natl Acad Sci U S A (1981) 1.07
They don't all look alike: individuated impressions of other racial groups. J Pers Soc Psychol (1993) 1.07
Measurement of putrescine, spermidine, and spermine in physiological fluids by use of an amino acid analyzer. Clin Chem (1973) 1.07
Past and current obesity in Koreans with non-insulin-dependent diabetes mellitus. Diabetes Res Clin Pract (1997) 1.07
Short-term fluoride release from various aesthetic restorative materials. Oper Dent (2002) 1.07
Structural features of nonpeptide prenyl pyrophosphates that determine their antigenicity for human gamma delta T cells. J Immunol (2001) 1.06
Alterations of Fas (APO-1/CD95) gene in transitional cell carcinomas of urinary bladder. Cancer Res (1999) 1.06
Localized proton MR spectroscopic detection of nonketotic hyperglycinemia in an infant. Korean J Radiol (2001) 1.06
Changes in L-ornithine decarboxylase activity during the cell cycle. Biochem Biophys Res Commun (1976) 1.06
Wernicke's encephalopathy: atypical manifestation at MR imaging. AJNR Am J Neuroradiol (2001) 1.06
Augmentation of tumor metastasis by platelet-activating factor. Cancer Res (1996) 1.05
Electrophysiological interactions of enkephalins with neuronal circuitry in the rat hippocampus. II. Effects on interneuron excitability. Brain Res (1980) 1.05
Short stature in Korean women: a contribution to the multifactorial predisposition to gestational diabetes mellitus. Diabetologia (1998) 1.05
Prosthetic reconstruction for tumours of the distal tibia and fibula. J Bone Joint Surg Br (1999) 1.05
Crystalline amorphous semiconductor superlattice. Phys Rev Lett (2008) 1.04
Conformationally restricted analogues of 1N,14N-bisethylhomospermine (BE-4-4-4): synthesis and growth inhibitory effects on human prostate cancer cells. J Med Chem (2001) 1.04
A molecular cytogenetic analysis of 7q31 in prostate cancer. Cancer Res (1998) 1.03
Polymorphisms of KCNJ11 (Kir6.2 gene) are associated with Type 2 diabetes and hypertension in the Korean population. Diabet Med (2007) 1.03
Incidence of presbycusis of Korean populations in Seoul, Kyunggi and Kangwon provinces. J Korean Med Sci (2000) 1.03
Clinical evaluation of DFN3 patients with deletions in the POU3F4 locus and detection of carrier female using MLPA. Clin Genet (2010) 1.03
Ultrasound findings of iodide mumps. Br J Radiol (2005) 1.02
HIV integrase inhibitory activity of Agastache rugosa. Arch Pharm Res (1999) 1.02
Sonographically guided ethanol sclerotherapy for benign thyroid cysts: results in 22 patients. AJR Am J Roentgenol (2000) 1.02
Mutation of p53 and K-ras, and loss of heterozygosity of APC in intrahepatic cholangiocarcinoma. Lab Invest (1999) 1.01
Genetic association study of adiponectin polymorphisms with risk of Type 2 diabetes mellitus in Korean population. Diabet Med (2005) 1.01
MR imaging of central diabetes insipidus: a pictorial essay. Korean J Radiol (2001) 1.01
Somatic mutations of TRAIL-receptor 1 and TRAIL-receptor 2 genes in non-Hodgkin's lymphoma. Oncogene (2001) 1.01
The corpus callosum and lateral ventricles in children with attention-deficit hyperactivity disorder: a brain magnetic resonance imaging study. Biol Psychiatry (1996) 1.01
Artificial induction of intravascular lipolysis by lipid-heparin infusion leads to insulin resistance in man. Diabetologia (1988) 1.00
Changes in polyamine metabolism in WI38 cells stimulated to proliferate. Exp Cell Res (1975) 1.00
Somatic mutational mechanisms involved in intestinal tumor formation in Min mice. Cancer Res (1997) 1.00
Immunoglobulin E-dependent active fatal anaphylaxis in mast cell-deficient mice. J Exp Med (1998) 1.00
Absence of mutations in the kinase domain of the Met gene and frequent expression of Met and HGF/SF protein in primary gastric carcinomas. APMIS (2000) 1.00
Polyamine metabolism in a rat brain tumor cell line: its relationship to the growth rate. J Cell Physiol (1975) 1.00
Chest wall implantation of carcinoma after fine needle aspiration biopsy. Yonsei Med J (1994) 0.99