Published in J Cell Biochem on May 01, 1991
Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes. Proc Natl Acad Sci U S A (2007) 2.11
Novel oligoamine analogues inhibit lysine-specific demethylase 1 and induce reexpression of epigenetically silenced genes. Clin Cancer Res (2009) 1.87
A proposed function for spermine and spermidine: protection of replicating DNA against damage by singlet oxygen. Proc Natl Acad Sci U S A (1992) 1.20
Polyamines and cancer: implications for chemotherapy and chemoprevention. Expert Rev Mol Med (2013) 1.18
Polyamines alter sequence-specific DNA-protein interactions. Nucleic Acids Res (1995) 1.14
Novel synthetic polyamines are effective in the treatment of experimental microsporidiosis, an opportunistic AIDS-associated infection. Antimicrob Agents Chemother (2002) 1.03
Polyamine analogs modulate gene expression by inhibiting lysine-specific demethylase 1 (LSD1) and altering chromatin structure in human breast cancer cells. Amino Acids (2011) 1.03
Formation of DNA nanoparticles in the presence of novel polyamine analogues: a laser light scattering and atomic force microscopic study. Nucleic Acids Res (2004) 1.02
Bidentate RNA-magnesium clamps: on the origin of the special role of magnesium in RNA folding. RNA (2010) 0.95
Mutations in the Drosophila melanogaster gene encoding S-adenosylmethionine synthetase [corrected] suppress position-effect variegation. Genetics (1996) 0.93
Base-pair opening and spermine binding--B-DNA features displayed in the crystal structure of a gal operon fragment: implications for protein-DNA recognition. Nucleic Acids Res (1995) 0.93
Polyamine analogues down-regulate estrogen receptor alpha expression in human breast cancer cells. J Biol Chem (2006) 0.92
On the interpretation of Raman spectra of 1-aminooxy-spermine/DNA complexes. Nucleic Acids Res (2004) 0.92
Polyamine structural effects on the induction and stabilization of liquid crystalline DNA: potential applications to DNA packaging, gene therapy and polyamine therapeutics. Nucleic Acids Res (2002) 0.91
Differential effects of spermine and its analogues on the structures of polynucleotides complexed with ethidium bromide. Biochem J (1993) 0.91
Nitric oxide counters ethylene effects on ripening fruits. Plant Signal Behav (2012) 0.89
Probing tRNA interaction with biogenic polyamines. RNA (2010) 0.89
Manipulation of the expression of regulatory genes of polyamine metabolism results in specific alterations of the cell-cycle progression. Biochem J (2001) 0.85
Oligoamine analogues in combination with 2-difluoromethylornithine synergistically induce re-expression of aberrantly silenced tumour-suppressor genes. Biochem J (2012) 0.85
Synthesis and growth regulatory activity of a prototype member of a new family of aminothiol radioprotectors. Bioorg Med Chem Lett (2011) 0.85
Polyamines preferentially interact with bent adenine tracts in double-stranded DNA. Nucleic Acids Res (2005) 0.83
Regulation of gene expression by PrrA in Rhodobacter sphaeroides 2.4.1: role of polyamines and DNA topology. J Bacteriol (2009) 0.82
The structure of polyamine analogues determines haemoglobin production and cytotoxicity in murine erythroleukaemia cells. Biochem J (1995) 0.80
Coordination Reactions and Noncovalent Interactions of Polyamines with Nucleotides in Binary Systems and with Nucleotides and Copper(II) Ion in Ternary Systems. Bioinorg Chem Appl (2010) 0.80
Effect of polyamine depletion on caspase activation: a study with spermine synthase-deficient cells. Biochem J (2001) 0.79
Spermine uptake is necessary to induce haemoglobin synthesis in murine erythroleukaemia cells. Biochem J (1995) 0.77
Amine oxidase copper-containing 1 (AOC1) is a downstream target gene of the Wilms tumor protein, WT1, during kidney development. J Biol Chem (2014) 0.77
The effect of polyamines on the binding of anti-DNA antibodies from patients with SLE and normal human subjects. Clin Immunol (2014) 0.76
Radioprotective efficacy and toxicity of a new family of aminothiol analogs. Int J Radiat Biol (2013) 0.75
The B-DNA dodecamer at high resolution reveals a spine of water on sodium. Biochemistry (1998) 2.68
X-ray structure of a DNA decamer containing 7,8-dihydro-8-oxoguanine. Proc Natl Acad Sci U S A (1995) 2.30
Structural comparison of anticancer drug-DNA complexes: adriamycin and daunomycin. Biochemistry (1990) 2.26
HEPATIC DYSFUNCTION IN MALARIA. Science (1944) 1.88
Structure of the potassium form of CGCGAATTCGCG: DNA deformation by electrostatic collapse around inorganic cations. Biochemistry (1998) 1.79
Locating monovalent cations in the grooves of B-DNA. Biochemistry (2001) 1.73
The discrepancy-attribution hypothesis: II. Expectation, uncertainty, surprise, and feelings of familiarity. J Exp Psychol Learn Mem Cogn (2001) 1.71
Ornithine decarboxylase is important in intestinal mucosal maturation and recovery from injury in rats. Science (1980) 1.61
DNA structure: cations in charge? Curr Opin Struct Biol (1999) 1.61
Molecular mechanics of the interactions of spermine with DNA: DNA bending as a result of ligand binding. Nucleic Acids Res (1990) 1.46
Atomic-resolution structure of the cellulose synthase regulator cyclic diguanylic acid. Proc Natl Acad Sci U S A (1990) 1.39
Polyamines: a high correlation with cell replication. FEBS Lett (1975) 1.36
Spermine-DNA interactions: a theoretical study. Proc Natl Acad Sci U S A (1986) 1.36
Structure of the pure-spermine form of Z-DNA (magnesium free) at 1-A resolution. Biochemistry (1991) 1.33
Influence of the dynamic positions of cations on the structure of the DNA minor groove: sequence-dependent effects. J Am Chem Soc (2001) 1.29
Why do strangers feel familiar, but friends don't? A discrepancy-attribution account of feelings of familiarity. Acta Psychol (Amst) (1998) 1.26
Structure of DNA-porphyrin complex. Biochemistry (1996) 1.23
The low-temperature crystal structure of the pure-spermine form of Z-DNA reveals binding of a spermine molecule in the minor groove. Biochemistry (1994) 1.19
Protonated base pairs explain the ambiguous pairing properties of O6-methylguanine. Proc Natl Acad Sci U S A (1987) 1.19
A double-blind, placebo-controlled study of oral nalmefene for alcohol dependence. Arch Gen Psychiatry (1999) 1.16
Monoamine-containing neurons in planaria. J Comp Neurol (1970) 1.16
Effects of variation in the structure of spermine on the association with DNA and the induction of DNA conformational changes. Biochem J (1990) 1.14
More sensitive automated detection of polyamines in physiological fluids and tissue extracts with omicron-phthalaldehyde. Clin Chem (1975) 1.13
Chemical reactivity of potassium permanganate and diethyl pyrocarbonate with B DNA: specific reactivity with short A-tracts. Biochemistry (1990) 1.10
Measurement of bilirubin and its monoconjugates and diconjugates in human serum by alkaline methanolysis and high-performance liquid chromatography. J Lab Clin Med (1980) 1.10
Conformationally restricted analogues of 1N,12N-bisethylspermine: synthesis and growth inhibitory effects on human tumor cell lines. J Med Chem (1998) 1.10
A novel assay for drug-DNA binding mode, affinity, and exclusion number: scanning force microscopy. Proc Natl Acad Sci U S A (1996) 1.09
Molecular dynamics of spermine-DNA interactions: sequence specificity and DNA bending for a simple ligand. Nucleic Acids Res (1989) 1.09
Polyamines are necessary for the survival of human small-cell lung carcinoma in culture. Proc Natl Acad Sci U S A (1981) 1.07
Measurement of putrescine, spermidine, and spermine in physiological fluids by use of an amino acid analyzer. Clin Chem (1973) 1.07
Changes in L-ornithine decarboxylase activity during the cell cycle. Biochem Biophys Res Commun (1976) 1.06
Divalent cations stabilize unstacked conformations of DNA and RNA by interacting with base pi systems. Biochemistry (1998) 1.05
The source of feelings of familiarity: the discrepancy-attribution hypothesis. J Exp Psychol Learn Mem Cogn (2000) 1.05
Diabetes insipidus in uricase-deficient mice: a model for evaluating therapy with poly(ethylene glycol)-modified uricase. J Am Soc Nephrol (2001) 1.04
Conformationally restricted analogues of 1N,14N-bisethylhomospermine (BE-4-4-4): synthesis and growth inhibitory effects on human prostate cancer cells. J Med Chem (2001) 1.04
Preschoolers' and adults' reliance on object shape and object function for lexical extension. J Exp Child Psychol (1999) 1.01
Somatic mutational mechanisms involved in intestinal tumor formation in Min mice. Cancer Res (1997) 1.00
Changes in polyamine metabolism in WI38 cells stimulated to proliferate. Exp Cell Res (1975) 1.00
The discrepancy-attribution hypothesis: I. The heuristic basis of feelings of familiarity. J Exp Psychol Learn Mem Cogn (2001) 1.00
Polyamine metabolism in a rat brain tumor cell line: its relationship to the growth rate. J Cell Physiol (1975) 1.00
Biochemical markers of central nervous system tumors measured in cerebrospinal fluid and their potential use in diagnosis and patient management: a review. J Natl Cancer Inst (1979) 0.99
Migration of electrons and holes in crystalline d(CGATCG)-anthracycline complexes X-irradiated at 4 K. Radiat Res (1998) 0.98
Interaction of a polyamine analogue, 1,19-bis-(ethylamino)-5,10,15- triazanonadecane (BE-4-4-4-4), with DNA and effect on growth, survival, and polyamine levels in seven human brain tumor cell lines. Cancer Res (1993) 0.97
Water ring structure at DNA interfaces: hydration and dynamics of DNA-anthracycline complexes. Biochemistry (1994) 0.97
New DNA polymorphism: evidence for a low salt, left-handed form of poly(dG-m5dC). Nucleic Acids Res (1985) 0.96
A stopped-flow H-D exchange kinetic study of spermine-polynucleotide interactions. Nucleic Acids Res (1987) 0.96
Drug-induced DNA repair: X-ray structure of a DNA-ditercalinium complex. Proc Natl Acad Sci U S A (1991) 0.96
Effect of methylglyoxal-bis (guanylhydrazone), an inhibitor of spermidine and spermine synthesis, on cell cycle traverse. Eur J Cancer (1977) 0.96
Growth regulatory effects of cyclic AMP and polyamine depletion are dissociable in cultured mouse lymphoma cells. J Cell Biol (1983) 0.96
Stabilization of erythrocyte membranes by polyamines. Proc Natl Acad Sci U S A (1983) 0.95
Correlation between the effects of polyamine analogues on DNA conformation and cell growth. Cancer Res (1989) 0.95
Biphasic stimulation of polyamine biosynthesis in primary mouse kidney cells by infection with polyoma virus:uncoupling from DNA and rRNA synthesis. Proc Natl Acad Sci U S A (1976) 0.94
Sensitization of 9L rat brain gliosarcoma cells to 1,3-bis(2-chloroethyl)-1-nitrosourea by alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor. Cancer Res (1981) 0.93
Simultaneous measurement of phenobarbital, phenytoin, primidone, ethosuximide, and carbamazepine in serum by high-pressure liquid chromatography. Clin Chem (1977) 0.93
Induction of DNA topoisomerase II-mediated DNA cleavage by beta-lapachone and related naphthoquinones. Cancer Res (1997) 0.93
Depletion of 9L rat brain tumor cell polyamine content by treatment with D,L-alpha-difluoromethylornithine inhibits proliferation and the G1 to S transition. Exp Cell Res (1981) 0.93
The interaction of spermine and pentamines with DNA. Biochem J (1987) 0.92
Polyamine content of AKR leukemic cells in relation to the cell cycle. Cancer Res (1973) 0.91
Polyamines in clinical disorders. West J Med (1985) 0.91
A new model for disruption of the ornithine decarboxylase gene, SPE1, in Saccharomyces cerevisiae exhibits growth arrest and genetic instability at the MAT locus. Biochem J (1995) 0.91
Differential effects of spermine and its analogues on the structures of polynucleotides complexed with ethidium bromide. Biochem J (1993) 0.91
Potentiation of the antitumor therapeutic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea by alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor. Cancer Res (1981) 0.90
Prediction of human tumor cell chemosensitivity using the sister chromatid exchange assay. Cancer Res (1986) 0.90
Retracted Polyamine depletion influences drug-induced chromosomal damage. Science (1982) 0.89
Antizyme and antizyme inhibitor activities influence cellular responses to polyamine analogs. Amino Acids (2007) 0.89
Freeze-fracturing of monolayers (capillary layers) of cell, membranes and viruses: some technical considerations. J Microsc (1977) 0.88
Molecular basis of inward rectification: structural features of the blocker defined by extended polyamine analogs. Mol Pharmacol (2005) 0.88
Depletion of intracellular putrescine and spermidine by alpha-difluromethylornithine does not inhibit proliferation of 9L rat brain tumor cells. Biochem Biophys Res Commun (1979) 0.88
Melting of a DNA hairpin without hyperchromism. Biochemistry (1998) 0.88
Depletion of intracellular polyamines may alter DNA conformation in 9L rat brain tumor cells. Science (1983) 0.88
Ultrastructure of ventral membranes of rat hepatocytes spread on type IV collagen. Eur J Cell Biol (1986) 0.88
The relationship of polyamines in cerebrospinal fluid to the presence of central nervous system tumors. Cancer Res (1976) 0.87
Oxyanion-mediated inhibition of serine proteases. Biochemistry (1998) 0.87
Recognition of Z-RNA and Z-DNA determinants by polyamines in solution: experimental and theoretical studies. J Biomol Struct Dyn (1988) 0.87
DNA distortion in bis-intercalated complexes. Biochemistry (1994) 0.87
Brain Tumor Working Group Report on the 9th International Conference on Brain Tumor Research and Therapy. Organ System Program, National Cancer Institute. J Neurooncol (1993) 0.86
The polyamine analog PG11047 potentiates the antitumor activity of cisplatin and bevacizumab in preclinical models of lung and prostate cancer. Cancer Chemother Pharmacol (2009) 0.86
CSF polyamines: a new and important means of monitoring patients with medulloblastoma. Cancer (1981) 0.86
Effect of polyamine depletion on chromatin structure in U-87 MG human brain tumour cells. Biochem J (1992) 0.86
A clinical and molecular genetic study of dentatorubropallidoluysian atrophy in four European families. Ann Neurol (1995) 0.86
Inhibition of trypsin and thrombin by amino(4-amidinophenyl)methanephosphonate diphenyl ester derivatives: X-ray structures and molecular models. Biochemistry (1996) 0.85
Structure of a DNA-bisdaunomycin complex. Biochemistry (1997) 0.85
Phase I-II clinical trial with alpha-difluoromethylornithine--an inhibitor of polyamine biosynthesis. Eur J Cancer Clin Oncol (1987) 0.85
Decreased cytotoxicity of cis-diamminedichloroplatinum(II) by alpha-difluoromethylornithine depletion of polyamines in 9L rat brain tumor cells in vitro. Cancer Res (1982) 0.84
Increased polyamine concentrations in the cerebrospinal fluid of patients with brain tumors. Int J Cancer (1974) 0.84
An automated micromethod for the quantitative analysis of di- and polyamines utilizing a sensitive high pressure liquid chromatographic procedure. FEBS Lett (1974) 0.84
Role of ornithine decarboxylase suppression and polyamine depletion in the antiproliferative activity of polyamine analogs. Mol Pharmacol (1992) 0.84
cis-Unsaturated analogues of 3,8,13,18,23-pentaazapentacosane (BE-4-4-4-4): synthesis and growth inhibitory effects on human prostate cancer cell lines. J Med Chem (2001) 0.84
Effects of cationic charge on three-dimensional structures of intercalative complexes: structure of a bis-intercalated DNA complex solved by MAD phasing. Curr Med Chem (2000) 0.83
Relationship of urinary polyamines to tumor activity and tumor volume in patients. Cancer Res (1984) 0.83