Published in FEBS Lett on October 20, 1986
Enzymatic properties of de novo-type mouse DNA (cytosine-5) methyltransferases. Nucleic Acids Res (2001) 2.36
De novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5-)-methyltransferase. Mol Cell Biol (1996) 2.26
DNA substrate specificity of pea DNA methylase. Biochem J (1993) 0.81
Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3. Nat Genet (2000) 5.50
Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53. Science (1996) 5.17
X-chromosome inactivation and cell memory. Trends Genet (1992) 3.76
Patterns of p53 G-->T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke. Carcinogenesis (2001) 2.66
Maternal-specific footprints at putative CTCF sites in the H19 imprinting control region give evidence for insulator function. Curr Biol (2000) 2.46
Targeting of lung cancer mutational hotspots by polycyclic aromatic hydrocarbons. J Natl Cancer Inst (2000) 2.27
Slow repair of pyrimidine dimers at p53 mutation hotspots in skin cancer. Science (1994) 2.21
Hypermethylation of the cpG island of Ras association domain family 1A (RASSF1A), a putative tumor suppressor gene from the 3p21.3 locus, occurs in a large percentage of human breast cancers. Cancer Res (2001) 2.18
In vivo structure of the human cdc2 promoter: release of a p130-E2F-4 complex from sequences immediately upstream of the transcription initiation site coincides with induction of cdc2 expression. Mol Cell Biol (1995) 1.93
Cyclobutane pyrimidine dimers are responsible for the vast majority of mutations induced by UVB irradiation in mammalian cells. J Biol Chem (2001) 1.80
The tumor suppressor RASSF1A in human carcinogenesis: an update. Histol Histopathol (2005) 1.76
Cytosine methylation determines hot spots of DNA damage in the human P53 gene. Proc Natl Acad Sci U S A (1997) 1.69
Complete and tissue-independent methylation of CpG sites in the p53 gene: implications for mutations in human cancers. Oncogene (1995) 1.57
Slow repair of bulky DNA adducts along the nontranscribed strand of the human p53 gene may explain the strand bias of transversion mutations in cancers. Oncogene (1998) 1.38
Epigenetic inactivation of the Ras-association domain family 1 (RASSF1A) gene and its function in human carcinogenesis. Histol Histopathol (2003) 1.38
The DNA damage spectrum produced by simulated sunlight. J Mol Biol (2000) 1.31
In vivo protein-DNA interactions at the c-jun promoter: preformed complexes mediate the UV response. Mol Cell Biol (1993) 1.29
DNA repair domains within a human gene: selective repair of sequences near the transcription initiation site. EMBO J (1996) 1.25
Ligation-mediated PCR improves the sensitivity of methylation analysis by restriction enzymes and detection of specific DNA strand breaks. Nucleic Acids Res (1990) 1.24
Isolation and characterization of DNA cytosine 5-methyltransferase from human placenta. Biochim Biophys Acta (1983) 1.20
Hypermethylation of the CpG island of the RASSF1A gene in ovarian and renal cell carcinomas. Int J Cancer (2001) 1.20
Sunlight induces pyrimidine dimers preferentially at 5-methylcytosine bases. Cancer Res (1997) 1.19
Extension product capture improves genomic sequencing and DNase I footprinting by ligation-mediated PCR. Nucleic Acids Res (1992) 1.17
The CpG island of the novel tumor suppressor gene RASSF1A is intensely methylated in primary small cell lung carcinomas. Oncogene (2001) 1.17
The distribution of UV photoproducts along the human p53 gene and its relation to mutations in skin cancer. Oncogene (1993) 1.15
Cyclobutane pyrimidine dimers form preferentially at the major p53 mutational hotspot in UVB-induced mouse skin tumors. Carcinogenesis (2000) 1.15
Mapping of UV photoproducts within ras proto-oncogenes in UV-irradiated cells: correlation with mutations in human skin cancer. Oncogene (1992) 1.11
UV light as a footprinting agent: modulation of UV-induced DNA damage by transcription factors bound at the promoters of three human genes. J Mol Biol (1995) 1.11
UV damage and repair mechanisms in mammalian cells. Bioessays (1996) 1.08
PCR-aided DNaseI footprinting of single copy gene sequences in permeabilized cells. Nucleic Acids Res (1990) 1.08
Inhibition of transcription factor binding by ultraviolet-induced pyrimidine dimers. Biochemistry (1996) 1.05
Constitutive protection of E2F recognition sequences in the human thymidine kinase promoter during cell cycle progression. J Biol Chem (1997) 1.03
Similarities in sunlight-induced mutational spectra of CpG-methylated transgenes and the p53 gene in skin cancer point to an important role of 5-methylcytosine residues in solar UV mutagenesis. J Mol Biol (2001) 1.01
The mechanism of action of rat liver DNA methylase. 3. Nucleotide requirements for binding and methylation. Biochim Biophys Acta (1972) 1.01
Frequent epigenetic inactivation of cystatin M in breast carcinoma. Oncogene (2006) 0.99
Sequence-specific and domain-specific DNA repair in xeroderma pigmentosum and Cockayne syndrome cells. J Biol Chem (1997) 0.99
Sequence and time-dependent deamination of cytosine bases in UVB-induced cyclobutane pyrimidine dimers in vivo. J Mol Biol (1998) 0.98
Characterization of novel parent-specific epigenetic modifications upstream of the imprinted mouse H19 gene. Mol Cell Biol (1998) 0.98
In vivo evidence for binding of p53 to consensus binding sites in the p21 and GADD45 genes in response to ionizing radiation. Oncogene (1997) 0.98
Lack of gene- and strand-specific DNA repair in RNA polymerase III-transcribed human tRNA genes. Mol Cell Biol (1997) 0.95
Cell cycle-independent removal of UV-induced pyrimidine dimers from the promoter and the transcription initiation domain of the human CDC2 gene. Nucleic Acids Res (2000) 0.95
Involvement of 5-methylcytosine in sunlight-induced mutagenesis. J Mol Biol (1999) 0.95
The DNA methylation landscape of small cell lung cancer suggests a differentiation defect of neuroendocrine cells. Oncogene (2012) 0.94
DNA methyltransferase polypeptides in mouse and human cells. Biochim Biophys Acta (1986) 0.94
Distribution pattern and enzymic hypermethylation of inverted repetitive DNA sequences in P815 mastocytoma cells. Biochim Biophys Acta (1979) 0.93
Unmethylated DNA in mouse L cells. I. DNA fibre autoradiography. Biochim Biophys Acta (1976) 0.93
Processing of UV damage in vitro by FEN-1 proteins as part of an alternative DNA excision repair pathway. Biochemistry (1999) 0.92
Frequent promoter methylation of tumor-related genes in sporadic and men2-associated pheochromocytomas. Exp Clin Endocrinol Diabetes (2005) 0.92
Quantitation and mapping of aflatoxin B1-induced DNA damage in genomic DNA using aflatoxin B1-8,9-epoxide and microsomal activation systems. Mutat Res (1999) 0.91
UV-induced DNA damage and mutations in Hupki (human p53 knock-in) mice recapitulate p53 hotspot alterations in sun-exposed human skin. Cancer Res (2001) 0.91
The p53 codon 249 mutational hotspot in hepatocellular carcinoma is not related to selective formation or persistence of aflatoxin B1 adducts. Oncogene (1998) 0.91
In vivo structure of two divergent promoters at the human PCNA locus. Synthesis of antisense RNA and S phase-dependent binding of E2F complexes in intron 1. J Biol Chem (1999) 0.91
RASSF1A interacts with and activates the mitotic kinase Aurora-A. Oncogene (2008) 0.90
Loss of Rassf1a enhances p53-mediated tumor predisposition and accelerates progression to aneuploidy. Oncogene (2010) 0.90
In vivo protein-DNA interactions at the c-jun promoter in quiescent and serum-stimulated fibroblasts. J Cell Biochem (1995) 0.89
Purification and characterization of mammalian DNA methyltransferases by use of monoclonal antibodies. J Biol Chem (1985) 0.88
Intracellular distribution of DNA methyltransferase during the cell cycle. FEBS Lett (1988) 0.88
Enzymatic DNA methylation in higher eukaryotes. Int J Biochem (1980) 0.88
Genomic structure and mutation screening of the E2F4 gene in human tumors. Int J Cancer (2000) 0.87
The transcription-repair coupling factor CSA is required for efficient repair only during the elongation stages of RNA polymerase II transcription. Mutat Res (1998) 0.87
Alteration of enzymatic methylation of DNA cytosines by chemical carcinogens: a mechanism involved in the initiation of carcinogenesis. J Natl Cancer Inst (1983) 0.87
Use of UvrABC nuclease to quantify benzo[a]pyrene diol epoxide-DNA adduct formation at methylated versus unmethylated CpG sites in the p53 gene. Carcinogenesis (1999) 0.86
Hypomethylation of DNA in Raji cells after treatment with N-methyl-N-nitrosourea. Carcinogenesis (1981) 0.86
Impaired enzymatic methylation of BPDE-modified DNA. Carcinogenesis (1984) 0.85
TP53 mutation spectrum in lung cancers and mutagenic signature of components of tobacco smoke: lessons from the IARC TP53 mutation database. Mutagenesis (2001) 0.85
Sequence-specific detection of aristolochic acid-DNA adducts in the human p53 gene by terminal transferase-dependent PCR. Carcinogenesis (2001) 0.85
A high-resolution analysis of chromatin structure along p53 sequences. Mol Carcinog (1996) 0.85
Mapping of DNA alkylation sites induced by adozelesin and bizelesin in human cells by ligation-mediated polymerase chain reaction. Biochemistry (1994) 0.84
Two-dimensional restriction mapping by digestion with restriction endonucleases of DNA in agarose and polyacrylamide gels. J Biochem Biophys Methods (1984) 0.83
DNA methylation levels in acute human leukemia. Cancer Lett (1988) 0.83
Elevated level of enzymatic DNA methylation in cells treated with 1-beta-D-arabinofuranosylcytosine. Cancer Res (1982) 0.83
Aberrant de novo methylation of DNA after treatment of murine cells with N-acetoxy-N-2-acetylaminofluorene. Cancer Res (1983) 0.83
T cell receptor gamma chain variable gene rearrangements in acute lymphoblastic leukemias of T and B lineage. Eur J Immunol (1987) 0.83
Elevated transcriptional complexity and decrease in enzymatic DNA methylation in cells treated with L-ethionine. Cancer Res (1981) 0.82
Involvement of DNA damage and repair in mutational spectra. Mutat Res (2000) 0.82
Proliferation-associated expression of DNA methyltransferase in human embryonic lung cells. Virchows Arch B Cell Pathol Incl Mol Pathol (1989) 0.82
Synthesis and characterization of poly[d(G-z5C)]. B-Z transition and inhibition of DNA methylase. Biochemistry (1985) 0.81
The persistence of chromosomes in somatic cell hybrids correlates with the enzymatic hypermethylation of their DNA. Int J Biochem (1981) 0.81
Structure of mouse DNA (cytosine-5-)-methyltransferase. Eur J Biochem (1988) 0.81
Preparation of monoclonal antibodies against DNA-cytosine-5-methyltransferase from human placenta. Eur J Cell Biol (1984) 0.80
A rapid and efficient screening method for DNA restriction fragment length polymorphisms. Clin Genet (1987) 0.80
[Chromosomal structure of Pseudomonas testosteroni. II. Activity of the endogenous RNA-polymerase (author's transl)]. Z Naturforsch C (1976) 0.79
Mammalian DNA methylase: binding and methylation site selection. Hoppe Seylers Z Physiol Chem (1972) 0.79
Alteration of enzymatic DNA methylation by chemical carcinogens. Recent Results Cancer Res (1983) 0.79
Inhibition of enzymatic DNA methylation by N-methyl-N-nitro-N-nitrosoguanidine in human Raji lymphoblast-like cells. Int J Biochem (1981) 0.78
Isolation and characterization of proteins that stimulate the activity of mammalian DNA methyltransferase. Biochim Biophys Acta (1988) 0.78
Effect of carcinogen ethionine on enzymatic methylation of DNA sequences with various degrees of repetitiveness. Eur J Cancer (1979) 0.78
Improved in vivo dimethyl sulfate footprinting using AlkA protein: DNA-protein interactions at the mouse H19 gene promoter in primary embryo fibroblasts. Anal Biochem (2000) 0.78
Studies on drug resistance. II. Kinase patterns in P815 neoplasms sensitive and resistant to 1-beta-D-arabinofuranosylcytosine. Biochem Pharmacol (1970) 0.78
[Distribution and enzymic hypermethylation of inverted DNA repeats in different murine and human cells (author's transl)]. Z Naturforsch C (1979) 0.78
Oncogene amplifications, rearrangements, and restriction fragment length polymorphisms in human leukaemia. Eur J Cancer Clin Oncol (1987) 0.78