Published in J Chromatogr on September 19, 1986
Characterization of drug-protein interactions in blood using high-performance affinity chromatography. J Sep Sci (2009) 1.13
Characterization of drug interactions with serum proteins by using high-performance affinity chromatography. Curr Drug Metab (2011) 1.09
Characterization of solute binding at human serum albumin site II and its geometry using a biochromatographic approach. Biophys J (1999) 0.78
Enantioselective disposition of hydroxychloroquine after a single oral dose of the racemate to healthy subjects. Br J Clin Pharmacol (1995) 1.43
Automated ligand fishing using human serum albumin-coated magnetic beads. Anal Chem (2007) 1.13
Ligand and protein fishing with heat shock protein 90 coated magnetic beads. Anal Chem (2008) 1.06
Allosteric and competitive displacement of drugs from human serum albumin by octanoic acid, as revealed by high-performance liquid affinity chromatography, on a human serum albumin-based stationary phase. J Chromatogr (1992) 1.06
Interactions of racemic mefloquine and its enantiomers with P-glycoprotein in an immortalised rat brain capillary endothelial cell line, GPNT. Biochim Biophys Acta (2000) 1.03
Proteolysis-inducing factor is expressed in tumours of patients with gastrointestinal cancers and correlates with weight loss. Br J Cancer (2001) 1.03
Cytochrome P450 isoforms involved in metabolism of the enantiomers of verapamil and norverapamil. Br J Clin Pharmacol (1999) 1.02
Development and characterization of an immobilized human organic cation transporter based liquid chromatographic stationary phase. J Chromatogr B Analyt Technol Biomed Life Sci (2005) 1.02
{Beta}2-adrenergic receptor agonists inhibit the proliferation of 1321N1 astrocytoma cells. J Pharmacol Exp Ther (2010) 1.02
Pharmacophore modelling of stereoselective binding to the human organic cation transporter (hOCT1). Br J Pharmacol (2007) 1.00
Determination of the enantiomers of mefloquine in plasma and whole blood using a coupled achiral-chiral high-performance liquid chromatographic system. J Chromatogr (1990) 0.97
Stereoselective pharmacokinetics of mefloquine in healthy Caucasians after multiple doses. J Pharm Sci (1994) 0.96
Enantioselective binding to the human organic cation transporter-1 (hOCT1) determined using an immobilized hOCT1 liquid chromatographic stationary phase. Chirality (2005) 0.95
N-acetylation among HIV-positive patients and patients with AIDS: when is fast, fast and slow, slow? Clin Pharmacol Ther (1997) 0.95
Removal of methotrexate, leucovorin, and their metabolites by combined hemodialysis and hemoperfusion. Cancer (1988) 0.94
Characterization of the protein binding of chiral drugs by high-performance affinity chromatography. Interactions of R- and S-ibuprofen with human serum albumin. J Chromatogr A (1995) 0.94
Development and characterization of immobilized cannabinoid receptor (CB1/CB2) open tubular column for on-line screening. Anal Biochem (2011) 0.93
Immobilized nicotinic receptor stationary phase for on-line liquid chromatographic determination of drug-receptor affinities. Anal Biochem (1998) 0.92
Ifosfamide stereoselective dichloroethylation and neurotoxicity. Lancet (1994) 0.91
A pilot study of plasma metabolomic patterns from patients treated with ketamine for bipolar depression: evidence for a response-related difference in mitochondrial networks. Br J Pharmacol (2014) 0.91
Characterization of a multiple ligand-gated ion channel cellular membrane affinity chromatography column and identification of endogenously expressed receptors in astrocytoma cell lines. Anal Chem (2008) 0.90
High-performance liquid chromatography assay for simultaneous determination of dextromethorphan and its main metabolites in urine and in microsomal preparations. J Chromatogr B Biomed Sci Appl (2001) 0.90
Evidence of renal metabolism of ifosfamide to nephrotoxic metabolites. Life Sci (2000) 0.89
Direct stereochemical resolution of aspartame stereoisomers and their degradation products by high-performance liquid chromatography on a chiral crown ether based stationary phase. J Chromatogr (1990) 0.89
Pharmacokinetics and metabolism of (R,R)-methoxyfenoterol in rat. Xenobiotica (2010) 0.88
Determination of the enantiomers of albuterol in human and canine plasma by enantioselective high-performance liquid chromatography on a teicoplanin-based chiral stationary phase. Chirality (1998) 0.87
The synthesis and characterization of a nuclear membrane affinity chromatography column for the study of human breast cancer resistant protein (BCRP) using nuclear membranes obtained from the LN-229 cells. J Pharm Biomed Anal (2012) 0.87
Plasma concentrations of the enantiomers of halofantrine and its main metabolite in malaria patients. Eur J Clin Pharmacol (1994) 0.86
Stereoselective distribution of hydroxychloroquine in the rabbit following single and multiple oral doses of the racemate and the separate enantiomers. Chirality (1994) 0.86
The stereochemical resolution of the enantiomers of aspartame on an immobilized alpha-chymotrypsin HPLC chiral stationary phase: the effect of mobile-phase composition and enzyme activity. Chirality (1990) 0.86
Verapamil stereoisomers during racemic verapamil administration: effects of aging and comparisons to administration of individual stereoisomers. Clin Pharmacol Ther (1994) 0.86
Measurement of underivatized propranolol enantiomers in serum using a cellulose-tris(3,5-dimethylphenylcarbamate) high-performance liquid chromatographic (HPLC) chiral stationary phase. Pharm Res (1988) 0.85
Competitive and allosteric interactions in ligand binding to P-glycoprotein as observed on an immobilized P-glycoprotein liquid chromatographic stationary phase. Mol Pharmacol (2001) 0.85
Role of CYP2B6 and CYP3A4 in the in vitro N-dechloroethylation of (R)- and (S)-ifosfamide in human liver microsomes. Drug Metab Dispos (1999) 0.85
The clinical pharmacology of meperidine--comparison of routes of administration. J Clin Pharmacol (1976) 0.85
Enantioselective determination of hydroxychloroquine and its major metabolites in urine and the observation of a reversal in the (+)/(-)-hydroxychloroquine ratio. Chirality (1993) 0.84
Further biochemical characterization of an Na+ pump inhibitor purified from human urine. Eur J Biochem (1987) 0.84
A discordance of the cytochrome P450 2C19 genotype and phenotype in patients with advanced cancer. Br J Clin Pharmacol (2000) 0.84
Development of an immobilized P-glycoprotein stationary phase for on-line liquid chromatographic determination of drug-binding affinities. J Chromatogr B Biomed Sci Appl (2000) 0.84
Use of a human serum albumin-based stationary phase for high-performance liquid chromatography as a tool for the rapid determination of drug-plasma protein binding. J Pharm Sci (1993) 0.83
Requirements for initial assay validation and publication in J. Chromatography B. J Chromatogr B Biomed Sci Appl (1998) 0.83
Dextromethorphan as an in vivo probe for the simultaneous determination of CYP2D6 and CYP3A activity. J Chromatogr B Biomed Appl (1996) 0.83
Stereoselective verapamil disposition and dynamics in aging during racemic verapamil administration. J Pharmacol Exp Ther (1993) 0.83
Determination of hydroxychloroquine and its major metabolites in plasma using sequential achiral-chiral high-performance liquid chromatography. J Chromatogr (1992) 0.83
The in situ acetylation of an immobilized human serum albumin chiral stationary phase for high-performance liquid chromatography in the examination of drug-protein binding phenomena. Pharm Res (1992) 0.83
Stereoselective binding of 2,3-substituted 3-hydroxypropionic acids on an immobilised human serum albumin chiral stationary phase: stereochemical characterisation and quantitative structure-retention relationship study. J Chromatogr A (2000) 0.82
Prediction of drug binding to melanin using a melanin-based high-performance liquid chromatographic stationary phase and chemometric analysis of the chromatographic data. J Chromatogr (1993) 0.82
Stereochemical aspects of benzodiazepine binding to human serum albumin. II. Quantitative relationships between structure and enantioselective retention in high performance liquid affinity chromatography. Mol Pharmacol (1992) 0.82
Synthesis and characterization of liquid chromatographic columns containing the immobilized ligand binding domain of the estrogen related receptor alpha and estrogen related receptor gamma. J Pharm Biomed Anal (2010) 0.82
Whole blood concentrations of mefloquine enantiomers in healthy Thai volunteers. Eur J Clin Pharmacol (1994) 0.82
The determination of the enantiomers of halofantrine and monodesbutylhalofantrine in plasma and whole blood using sequential achiral/chiral high-performance liquid chromatography. J Pharm Biomed Anal (1992) 0.82
The enantioselective binding of mefloquine enantiomers to P-glycoprotein determined using an immobilized P-glycoprotein liquid chromatographic stationary phase. Pharm Res (2001) 0.82
Influence of dose of [6RS]leucovorin on reduced folate pools and 5-fluorouracil-mediated thymidylate synthase inhibition in human colon adenocarcinoma xenografts. Cancer Res (1990) 0.81
Genotype and phenotype of cytochrome P450 2D6 in human immunodeficiency virus-positive patients and patients with acquired immunodeficiency syndrome. Eur J Clin Pharmacol (2000) 0.81
Immobilized serum albumin: rapid HPLC probe of stereoselective protein-binding interactions. Chirality (1990) 0.81
Determination and modelling of stereoselective interactions of ligands with drug transporters: a key dimension in the understanding of drug disposition. Xenobiotica (2008) 0.80
Determination of the enantiomers of ifosfamide and its 2- and 3-N-dechloroethylated metabolites in plasma and urine using enantioselective gas chromatography with mass spectrometric detection. J Chromatogr (1993) 0.80
Simultaneous direct determination of the enantiomers of verapamil and norverapamil in plasma using a derivatized amylose high-performance liquid chromatographic chiral stationary phase. J Chromatogr (1992) 0.80
Stereoselective pharmacokinetics of ifosfamide and its 2- and 3-N-dechloroethylated metabolites in female cancer patients. Cancer Chemother Pharmacol (1996) 0.80
Determination of the stereoisomers of hydroxychloroquine and its major metabolites in plasma and urine following a single oral administration of racemic hydroxychloroquine. Semin Arthritis Rheum (1993) 0.80
Determination of p-aminosalicylic acid and its N-acetylated metabolite in human urine by capillary zone electrophoresis as a measure of in vivo N-acetyltransferase 1 activity. J Chromatogr B Biomed Sci Appl (1997) 0.80
The measurement of warfarin enantiomers in serum using coupled achiral/chiral, high-performance liquid chromatography (HPLC). Pharm Res (1988) 0.79
Improved chromatographic performance of a modified human albumin based stationary phase. Chirality (1997) 0.79
Determination of reduced and oxidized homocysteine and related thiols in plasma by thiol-specific pre-column derivatization and capillary electrophoresis with laser-induced fluorescence detection. J Chromatogr B Biomed Sci Appl (1999) 0.79
Determination of the antitumor agent depsipeptide in plasma by liquid chromatography on serial octadecyl stationary phases. J Chromatogr B Biomed Sci Appl (1998) 0.79
Determination of the enantiomeric composition of mexiletine and its four hydroxylated metabolites in urine by enantioselective capillary gas chromatography. Chirality (1996) 0.79
Separation of enantiomeric amines by ion-pair chromatography. J Chromatogr (1981) 0.79
Reverse-phase ion-pair chromatography of polyvalent ions using oligonucleotides as model substances. Anal Biochem (1982) 0.79
Cyclophosphamide versus ifosfamide: to use ifosfamide or not to use, that is the three-dimensional question. Curr Pharm Des (1999) 0.79
Direct determination of tamoxifen and its four major metabolites in plasma using coupled column high-performance liquid chromatography. J Chromatogr B Biomed Appl (1994) 0.78
Analytical and preparative high-performance liquid chromatographic separation of the enantiomers of ifosfamide, cyclophosphamide and trofosfamide and their determination in plasma. J Chromatogr (1989) 0.78
Influence of phenobarbital induction on the enantioselective N-dechloroethylation of ifosfamide enantiomers in the rat. Drug Metab Dispos (1994) 0.78
Immobilized horse liver alcohol dehydrogenase as an on-line high-performance liquid chromatographic enzyme reactor for stereoselective synthesis. Chirality (1999) 0.78
The determination of (-)-(S)- and (+)-(R)-ifosfamide in plasma using enantioselective gas chromatography: a validated assay for pharmacokinetic and clinical studies. Chirality (1989) 0.78
Verapamil decreases lymphocyte protein kinase C activity in humans. Clin Pharmacol Ther (1994) 0.78
Development of a chromatographic bioreactor based on immobilized beta-glucuronidase on monolithic support for the determination of dextromethorphan and dextrorphan in human urine. J Pharm Biomed Anal (2004) 0.78
Liquid chromatographic separation of the enantiomers of metoprolol and its alpha-hydroxy metabolite on Chiralcel OD for determination in plasma and urine. J Chromatogr (1991) 0.78
A population analysis of nebulized (R)-albuterol in dogs using a novel mixed gut-lung absorption PK-PD model. Pharm Res (2000) 0.78
Effect of protein-calorie malnutrition on cytochromes P450 and glutathione S-transferase. Eur J Drug Metab Pharmacokinet (1999) 0.78
Receptor independent effects on DNA replication by steroids. J Cell Biochem (1998) 0.78
A validated method for the determination of paracetamol and its glucuronide and sulphate metabolites in the urine of HIV+/AIDS patients using wavelength-switching UV detection. J Pharm Biomed Anal (1998) 0.77
Verapamil metabolite exposure in older and younger men during steady-state oral verapamil administration. Drug Metab Dispos (2000) 0.77
Glucuronidation and sulphation of paracetamol in HIV-positive patients and patients with AIDS. Br J Clin Pharmacol (1999) 0.77
Stereoselective binding of chiral ligands to single nucleotide polymorphisms of the human organic cation transporter-1 determined using cellular membrane affinity chromatography. Anal Biochem (2010) 0.77
Enantioselective induction of cyclophosphamide metabolism by phenytoin. Chirality (1999) 0.77
In vivo comparison of putative probes of CYP3A4/5 activity: erythromycin, dextromethorphan, and verapamil. Clin Pharmacol Ther (1999) 0.77
Phenytoin-induced alteration in the N-dechloroethylation of ifosfamide stereoisomers. Cancer Chemother Pharmacol (1997) 0.77
Direct analysis of the enantiomers of mexiletine and its metabolites in plasma and urine using an HPLC-CSP. J Pharm Biomed Anal (1994) 0.77
Application of an in vitro system in the study of chemotherapeutic drug effects on DNA replication. J Cell Biochem (1996) 0.77
Determination of metyrapone and the enantiomers of its chiral metabolite metyrapol in human plasma and urine using coupled achiral-chiral liquid chromatography. J Chromatogr B Biomed Appl (1995) 0.77
Efficacy, toxicity, pharmacokinetics, and in vitro metabolism of the enantiomers of ifosfamide in mice. Cancer Res (1990) 0.76
Labetalol pharmacokinetics and pharmacodynamics: evidence of stereoselective disposition. Clin Pharmacol Ther (1990) 0.76
A potentially toxic drug interaction between pethidine (meperidine) and phenobarbitone. Lancet (1977) 0.76
Liquid chromatographic method for the simultaneous determination of caffeine and fourteen caffeine metabolites in urine. J Chromatogr B Biomed Sci Appl (2000) 0.76
High-performance liquid chromatographic chiral stationary phase separation with filament-on thermospray mass spectrometric identification of the enantiomer contaminant (S)-(+)-methamphetamine. Anal Chem (1986) 0.76