PubRank

A Ashworth

Author PubWeight™ 231.28‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus. Cell 1992 6.26
2 An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1. Science 1995 6.03
3 3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase. Curr Biol 1997 5.66
4 Effect of community-based peer counsellors on exclusive breastfeeding practices in Dhaka, Bangladesh: a randomised controlled trial [see commments]. Lancet 2000 4.67
5 Controlled trial of three approaches to the treatment of severe malnutrition. Lancet 1995 4.59
6 Identification of the sites in MAP kinase kinase-1 phosphorylated by p74raf-1. EMBO J 1994 4.37
7 BRCA1 dysfunction in sporadic basal-like breast cancer. Oncogene 2006 3.91
8 Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome. Nature 1991 3.43
9 The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability. Oncogene 2006 3.27
10 Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences. EMBO J 2001 3.21
11 BRCA2 mutations in primary breast and ovarian cancers. Nat Genet 1996 2.91
12 Assay and expression of mitogen-activated protein kinase, MAP kinase kinase, and Raf. Methods Enzymol 1995 2.82
13 Xist has properties of the X-chromosome inactivation centre. Nature 1997 2.78
14 An SRY-related gene expressed during spermatogenesis in the mouse encodes a sequence-specific DNA-binding protein. EMBO J 1992 2.56
15 Isolation and sequence of a human cytochrome P-450 cDNA clone. Proc Natl Acad Sci U S A 1985 2.42
16 Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation. Nat Genet 1997 2.41
17 Basal-like breast carcinomas: clinical outcome and response to chemotherapy. J Clin Pathol 2006 2.40
18 Why have mortality rates for severe malnutrition remained so high? Bull World Health Organ 1996 2.39
19 Stimulation of the stress-activated mitogen-activated protein kinase subfamilies in perfused heart. p38/RK mitogen-activated protein kinases and c-Jun N-terminal kinases are activated by ischemia/reperfusion. Circ Res 1996 2.30
20 Expression of Xist during mouse development suggests a role in the initiation of X chromosome inactivation. Cell 1993 2.30
21 A conserved family of genes related to the testis determining gene, SRY. Nucleic Acids Res 1992 2.26
22 Absence of Brca2 causes genome instability by chromosome breakage and loss associated with centrosome amplification. Curr Biol 1999 2.17
23 Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets. Oncogene 2010 2.11
24 The dual specificity phosphatases M3/6 and MKP-3 are highly selective for inactivation of distinct mitogen-activated protein kinases. J Biol Chem 1996 2.04
25 Measuring hygiene practices: a comparison of questionnaires with direct observations in rural Zaïre. Trop Med Int Health 1997 1.99
26 Identification of six Tcp-1-related genes encoding divergent subunits of the TCP-1-containing chaperonin. Curr Biol 1994 1.87
27 Interaction between the product of the breast cancer susceptibility gene BRCA2 and DSS1, a protein functionally conserved from yeast to mammals. Mol Cell Biol 1999 1.77
28 Exploiting the DNA repair defect in BRCA mutant cells in the design of new therapeutic strategies for cancer. Cold Spring Harb Symp Quant Biol 2005 1.67
29 A short pseudoautosomal region in laboratory mice. Genome Res 2001 1.64
30 Array CGH profiling of favourable histology Wilms tumours reveals novel gains and losses associated with relapse. J Pathol 2006 1.63
31 Growth rates in children recovering from protein-calorie malnutrition. Br J Nutr 1969 1.62
32 The BRC repeats are conserved in mammalian BRCA2 proteins. Hum Mol Genet 1997 1.62
33 The Sry-related HMG box-containing gene Sox6 is expressed in the adult testis and developing nervous system of the mouse. Nucleic Acids Res 1995 1.61
34 Interventions for the control of diarrhoeal diseases among young children: weaning education. Bull World Health Organ 1985 1.59
35 Potential interventions for the prevention of childhood pneumonia in developing countries: improving nutrition. Am J Clin Nutr 1999 1.57
36 EGFR amplification and lack of activating mutations in metaplastic breast carcinomas. J Pathol 2006 1.57
37 Transgenic mice carrying an Xist-containing YAC. Hum Mol Genet 1996 1.56
38 MKP5, a new member of the MAP kinase phosphatase family, which selectively dephosphorylates stress-activated kinases. Oncogene 1999 1.55
39 DNA binding and bending properties of the post-meiotically expressed Sry-related protein Sox-5. Nucleic Acids Res 1994 1.54
40 Endo180, an endocytic recycling glycoprotein related to the macrophage mannose receptor is expressed on fibroblasts, endothelial cells and macrophages and functions as a lectin receptor. J Cell Sci 2000 1.50
41 LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1. Hum Mol Genet 2001 1.47
42 Evolutionary rate of a gene affected by chromosomal position. Curr Biol 1999 1.47
43 HEX: a novel homeobox gene expressed during haematopoiesis and conserved between mouse and human. Nucleic Acids Res 1993 1.38
44 Evaluating the clinical management of severely malnourished children--a study of two rural district hospitals. S Afr Med J 2001 1.37
45 The mitogen-activated protein kinase phosphatase-3 N-terminal noncatalytic region is responsible for tight substrate binding and enzymatic specificity. J Biol Chem 1998 1.37
46 A mouse model of basal-like breast carcinoma with metaplastic elements. J Pathol 2007 1.36
47 A contravention of Ohno's law in mice. Nat Genet 1995 1.34
48 Faltering in infant growth in less-developed countries. Lancet 1980 1.34
49 Calorie requirements of children recovering from protein-calorie manutrition. Lancet 1968 1.31
50 Community-based hygiene education to reduce diarrhoeal disease in rural Zaire: impact of the intervention on diarrhoeal morbidity. Int J Epidemiol 1994 1.31
51 Infant mortality in developing countries. Arch Dis Child 1982 1.30
52 New complexities for BRCA1 and BRCA2. Curr Biol 2001 1.30
53 Metabolic rates during recovery from protein-calorie malnutrition: the need for a new concept of specific dynamic action. Nature 1969 1.30
54 Expression, mutation and copy number analysis of platelet-derived growth factor receptor A (PDGFRA) and its ligand PDGFA in gliomas. Br J Cancer 2009 1.30
55 Microarray and histopathological analysis of tumours: the future and the past? Nat Rev Cancer 2001 1.28
56 Molecular cloning and functional characterization of a novel mitogen-activated protein kinase phosphatase, MKP-4. J Biol Chem 1997 1.27
57 A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1D. Oncogene 2007 1.27
58 The mouse Peutz-Jeghers syndrome gene Lkb1 encodes a nuclear protein kinase. Hum Mol Genet 1999 1.22
59 Genomic and immunophenotypical characterization of pure micropapillary carcinomas of the breast. J Pathol 2008 1.21
60 Molecular profiling of breast cancer: clinical implications. Br J Cancer 2004 1.19
61 A candidate spermatogenesis gene on the mouse Y chromosome is homologous to ubiquitin-activating enzyme E1. Nature 1991 1.18
62 Nuclear location and cell cycle regulation of the BRCA2 protein. Cancer Res 1997 1.17
63 Catch-up growth in children. Nutr Rev 1986 1.17
64 The Y* rearrangement in mice: new insights into a perplexing PAR. Cytogenet Cell Genet 1998 1.16
65 The genomic profile of HER2-amplified breast cancers: the influence of ER status. J Pathol 2008 1.14
66 Functions of the BRCA1 and BRCA2 genes. Curr Opin Genet Dev 1998 1.13
67 Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas. J Pathol 2008 1.13
68 Cloning and characterization of SOX5, a new member of the human SOX gene family. Genomics 1996 1.12
69 Influence of demographic, socioeconomic and environmental variables on childhood diarrhoea in a rural area of Zaire. J Trop Med Hyg 1994 1.12
70 Management of protein-energy malnutrition in Nigeria: an evaluation of the regimen at the Kersey Nutrition Rehabilitation Centre, Nigeria. Trans R Soc Trop Med Hyg 1995 1.11
71 The Breakthrough Generations Study: design of a long-term UK cohort study to investigate breast cancer aetiology. Br J Cancer 2011 1.09
72 Cloning and sequencing of POU-boxes expressed in mouse testis. Nucleic Acids Res 1990 1.09
73 Expression of sox11 gene duplicates in zebrafish suggests the reciprocal loss of ancestral gene expression patterns in development. Dev Dyn 2000 1.08
74 Prevalence of anemia in children 6-59 months old in the state of Pernambuco, Brazil. Rev Panam Salud Publica 2001 1.08
75 Breast-feeding among the urban poor in southern Brazil: reasons for termination in the first 6 months of life. Bull World Health Organ 1989 1.07
76 Targeting Tankyrase 1 as a therapeutic strategy for BRCA-associated cancer. Oncogene 2009 1.07
77 Effect of zinc supplementation on the morbidity, immune function, and growth of low-birth-weight, full-term infants in northeast Brazil. Am J Clin Nutr 1998 1.07
78 Establishment and characterisation of a new breast cancer xenograft obtained from a woman carrying a germline BRCA2 mutation. Br J Cancer 2010 1.06
79 Dysregulated TRK signalling is a therapeutic target in CYLD defective tumours. Oncogene 2011 1.06
80 Poly (ADP-ribose) polymerase (PARP) inhibitors for the treatment of advanced germline BRCA2 mutant prostate cancer. Ann Oncol 2013 1.06
81 The proteasome is involved in determining differential utilization of double-strand break repair pathways. Oncogene 2007 1.06
82 Analysis by array CGH of genomic changes associated with the progression or relapse of Wilms' tumour. J Pathol 2007 1.04
83 Cloning, chromosomal mapping and expression pattern of the mouse Brca2 gene. Hum Mol Genet 1997 1.02
84 Infant mortality in southern Brazil: a population based study of causes of death. Arch Dis Child 1987 1.02
85 Growth, morbidity, and mortality of children in Dhaka after treatment for severe malnutrition: a prospective study. Am J Clin Nutr 1998 1.02
86 Low birth weight and morbidity from diarrhea and respiratory infection in northeast Brazil. J Pediatr 1996 1.01
87 Interventions for the control of diarrhoeal diseases among young children: prevention of low birth weight. Bull World Health Organ 1985 1.00
88 Lung function and exercise performance of healthy Caribbean men and women of African ethnic origin. Q J Exp Physiol Cogn Med Sci 1972 1.00
89 Breastfeeding and early weaning practices in northeast Brazil: a longitudinal study. Pediatrics 2001 0.99
90 Complementation of byr1 in fission yeast by mammalian MAP kinase kinase requires coexpression of Raf kinase. Nature 1993 0.99
91 Determinants of age at menarche in the UK: analyses from the Breakthrough Generations Study. Br J Cancer 2010 0.98
92 A zinc finger protein-encoding gene expressed in the post-meiotic phase of spermatogenesis. Gene 1991 0.98
93 Isolation and characterisation of a uniquely regulated threonine, tyrosine phosphatase (TYP 1) which inactivates ERK2 and p54jnk. Oncogene 1995 0.98
94 Cloning, chromosomal localization and expression pattern of the POU domain gene Oct-11. Nucleic Acids Res 1993 0.97
95 Microarray-based comparative genomic hybridisation of breast cancer patients receiving neoadjuvant chemotherapy. Br J Cancer 2006 0.97
96 The threonine residues in MAP kinase kinase 1 phosphorylated by MAP kinase in vitro are also phosphorylated in nerve growth factor-stimulated rat phaeochromocytoma (PC12) cells. FEBS Lett 1994 0.97
97 FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium. Br J Cancer 2014 0.96
98 A gene spans the pseudoautosomal boundary in mice. Proc Natl Acad Sci U S A 1997 0.96
99 Structural variation of the pseudoautosomal region between and within inbred mouse strains. Proc Natl Acad Sci U S A 1996 0.95
100 The ZFY gene family in humans and mice. Trends Genet 1991 0.94
101 Ad lib. feeding during recovery from malnutrition. Br J Nutr 1974 0.93
102 Severe malnutrition in children: high case-fatality rates can be reduced. Afr Health 1997 0.93
103 Determinants of mental and motor development at 12 months in a low income population: a cohort study in northeast Brazil. Acta Paediatr 2004 0.93
104 Weaning-food viscosity and energy density: their effects on ad libitum consumption and energy intakes in Jamaican children. Am J Clin Nutr 1994 0.92
105 Cloning and sequence analysis of a rat liver cDNA coding for a phenobarbital-inducible microheterogenous cytochrome P-450 variant: regulation of its messenger level by xenobiotics. Gene 1983 0.91
106 Natural history of the dislocated hip in spastic cerebral palsy. Dev Med Child Neurol 1979 0.91
107 A high-throughput screen identifies PARP1/2 inhibitors as a potential therapy for ERCC1-deficient non-small cell lung cancer. Oncogene 2013 0.90
108 A role for JNK/SAPK in proliferation, but not apoptosis, of IL-3-dependent cells. Curr Biol 1997 0.90
109 An improved definition of mouse mammary epithelial side population cells. Cytotherapy 2005 0.90
110 Familial non-specific dementia maps to chromosome 3. Hum Mol Genet 1995 0.90
111 Costs of palliative care in the community, in hospitals and in hospices in the UK. Crit Rev Oncol Hematol 1999 0.89
112 JNK activation is not required for Fas-mediated apoptosis. Oncogene 1999 0.89
113 Protein requirements in tropical countries: nitrogen losses in sweat and their relation to nitrogen balance. Br J Nutr 1967 0.88
114 Frequent somatic deletion of the 13q12.3 locus encompassing BRCA2 in chronic lymphocytic leukemia. Blood 1996 0.88
115 Inhibition of aromatase expression by a psoralen-linked triplex-forming oligonucleotide targeted to a coding sequence. FEBS Lett 1995 0.87
116 Improving child survival: Malnutrition Task Force and the paediatrician's responsibility. Arch Dis Child 2006 0.87
117 Genome-wide screening for genetic changes in a matched pair of benign and prostate cancer cell lines using array CGH. Prostate Cancer Prostatic Dis 2005 0.87
118 Are breastfeeding promotion messages influencing mothers in Bangladesh? Results from an urban survey in Dhaka, Bangladesh. J Trop Pediatr 1999 0.87
119 The development of low birth weight term infants and the effects of the environment in northeast Brazil. J Pediatr 1998 0.87
120 FXY2/MID2, a gene related to the X-linked Opitz syndrome gene FXY/MID1, maps to Xq22 and encodes a FNIII domain-containing protein that associates with microtubules. Genomics 1999 0.87
121 The caudal neurosecretory system: control and function of a novel neuroendocrine system in fish. Biochem Cell Biol 2000 0.86
122 Malnutrition and metabolic rates. Nutr Rev 1970 0.86
123 BRCA1 and BRCA2 bind Stat5a and suppress its transcriptional activity. FEBS Lett 2002 0.86
124 The human FXY gene is located within Xp22.3: implications for evolution of the mammalian X chromosome. Hum Mol Genet 1998 0.86
125 Training nurses to save lives of malnourished children. Curationis 2006 0.85
126 Male breast cancer, age and sex chromosome aneuploidy. Br J Cancer 2013 0.85
127 Designing educational messages to improve weaning food hygiene practices of families living in poverty. Soc Sci Med 1997 0.85
128 Influence of heavy agricultural work during pregnancy on birthweight in northeast Brazil. Int J Epidemiol 1999 0.85
129 Practical aspects of dietary management during rehabilitation from severe protein-energy malnutrition. J Hum Nutr 1980 0.85
130 Treatment of malnutrition in Brazil: simple solutions to common problems. Trop Doct 1998 0.85
131 RNA interference screening demystified. J Clin Pathol 2009 0.85
132 Genomic profile of a secretory breast cancer with an ETV6-NTRK3 duplication. J Clin Pathol 2009 0.85
133 Report of the IDECG Working Group on effects of IUGR on infants, children and adolescents: immunocompetence, mortality, morbidity, body size, body composition, and physical performance. Eur J Clin Nutr 1998 0.84
134 Weaning in southern Brazil: is there a "weanling's dilemma"? J Nutr 1994 0.83
135 A member of the MAP kinase phosphatase gene family in mouse containing a complex trinucleotide repeat in the coding region. Hum Mol Genet 1996 0.83
136 Differential effect of phenobarbital and beta-naphthoflavone on the mRNAs coding for cytochrome P450 and NADPH cytochrome P450 reductase. FEBS Lett 1982 0.82
137 International differences in child mortality and the impact of malnutrition. Hum Nutr Clin Nutr 1982 0.82
138 Infant feeding practices in Kenya, Mexico and Malaysia. The rarity of the exclusively breast-fed infant. Hum Nutr Appl Nutr 1987 0.82
139 sox30: a novel zebrafish sox gene expressed in a restricted manner at the midbrain-hindbrain boundary during neurogenesis. Dev Genes Evol 1999 0.82
140 The influence of malnutrition on the postprandial metabolic rate and respiratory quotient. Br J Nutr 1972 0.81
141 Cytosine-based nucleoside analogs are selectively lethal to DNA mismatch repair-deficient tumour cells by enhancing levels of intracellular oxidative stress. Br J Cancer 2013 0.81
142 Ten steps to recovery. Child Health Dialogue 1996 0.81
143 Factors controlling the expression of genes coding for drug-metabolizing enzymes. Biochem Soc Trans 1983 0.81
144 Isolation of a human cytochrome P-450 reductase cDNA clone and localization of the corresponding gene to chromosome 7q11.2. Ann Hum Genet 1989 0.81
145 Control of aromatase in breast cancer cells and its importance for tumor growth. J Steroid Biochem Mol Biol 1993 0.81
146 Methodological approaches in a baseline study of diarrhoeal morbidity in weaning-age children in rural Zaire. Int J Epidemiol 1994 0.81
147 The pathology of familial breast cancer: How do the functions of BRCA1 and BRCA2 relate to breast tumour pathology? Breast Cancer Res 1999 0.80
148 A member of the caudal family of homeobox genes maps to the X-inactivation centre region of the mouse and human X chromosomes. Hum Mol Genet 1995 0.80
149 Near-patient platelet function testing in patients undergoing coronary artery surgery: a pilot study. Anaesthesia 2011 0.80
150 Cancer predisposition: where's the phosphate? Curr Biol 1998 0.80
151 Chromosomal localization of three human dual specificity phosphatase genes (DUSP4, DUSP6, and DUSP7). Genomics 1997 0.79
152 Zfyl encodes a nuclear sequence-specific DNA binding protein. FEBS Lett 1995 0.79
153 Effectiveness of nutrition centers in Ceará state, northeastern Brazil. Rev Panam Salud Publica 1998 0.79
154 Structure and expression of the gene encoding mouse t-complex polypeptide (Tcp-1). Gene 1992 0.79
155 Profiling familial breast cancer. Nat Med 2001 0.78
156 Biological effects of stable overexpression of aromatase in human hormone-dependent breast cancer cells. Br J Cancer 1994 0.78
157 Alternative splicing of the Drosophila PTEN gene. Biochim Biophys Acta 1999 0.78
158 Structure and chromosomal mapping of the TNF-alpha inducible endothelial protein 1 (Edp1) gene in the mouse. Biochim Biophys Acta 1998 0.77
159 International differences in infant mortality and the impact of malnutrition: a review. Hum Nutr Clin Nutr 1982 0.77
160 Infective complications of thoracic epidural. Br J Anaesth 2004 0.77
161 The mouse Ftzf1 gene required for gonadal and adrenal development maps to mouse chromosome 2. Genomics 1995 0.77
162 Patchy fur, a mouse coat mutation associated with X-Y nondisjunction, maps to the pseudoautosomal boundary region. Genomics 1998 0.77
163 Absorption of iron from maize (Zea mays L.) and soya beans (Glycine hispida Max.) in Jamaican infants. Br J Nutr 1973 0.77
164 A missense mutation in the BRCA2 gene in three siblings with ovarian cancer. Br J Cancer 1998 0.76
165 An in vivo model of intratumoural aromatase using aromatase-transfected MCF7 human breast cancer cells. Int J Cancer 1995 0.76
166 A survey of post-sternotomy chronic pain following cardiac surgery. Anaesthesia 2009 0.76
167 Effect of breastfeeding and morbidity on the development of low birthweight term babies in Brazil. Acta Paediatr 1999 0.76
168 Historical review of the changing pattern of infant feeding in developing countries: the case of Malaysia, the Caribbean, Nigeria and Zaire. Soc Sci Med 1987 0.76
169 Safety of cardiac surgery without blood transfusion: a retrospective study in Jehovah's Witness patients. Anaesthesia 2010 0.75
170 Construction of specific cosmids from YACs by homologous recombination in yeast. Nucleic Acids Res 1995 0.75
171 Influences on computer use in general practice. Report of a one-year study on behalf of the Royal College of General Practitioners. Occas Pap R Coll Gen Pract 1995 0.75
172 Is cell salvage safe in transnasal surgery? Anaesthesia 2010 0.75
173 Sequence of cDNA for Xenopus XZFY-1. Nucleic Acids Res 1992 0.75
174 Hydronephrosis. Practitioner 1966 0.75
175 Mapping of two zinc finger protein genes to mouse chromosomes 4 and 7. Mamm Genome 1995 0.75
176 Calorie and protein intakes and growth. Lancet 1969 0.75
177 Protein and 'malnutrition'. J Trop Pediatr 1985 0.75
178 Energy balance and growth: experience in treating children with malnutrition. Kidney Int 1978 0.75
179 Structure and expression of genes coding for components of the cytochrome P-450-mediated mono-oxygenase. Biochem Soc Trans 1987 0.75
180 Fighting malnutrition from hospital to home. Child Health Dialogue 1996 0.75
181 Progress in the treatment of protein-energy malnutrition. Proc Nutr Soc 1979 0.75
182 Infant and young child feeding. An annotated bibliography. Early Hum Dev 1982 0.75
183 Disease-gene relationship seen. Nature 1986 0.75
184 Should all patients be placed head down for internal jugular vein catheter insertion? Br J Hosp Med (Lond) 2010 0.75
185 Hydronephrosis. 2. Diagnostic investigations. Nurs Times 1968 0.75
186 Preface. Occas Pap R Coll Gen Pract 1995 0.75
187 Dietary manipulation of serum triglycerides. Arch Latinoam Nutr 1979 0.75
188 BRCA1 and BRCA2. Curr Biol 2000 0.75
189 A simple method for measuring calorie expenditures during sleep. Pflugers Arch 1969 0.75
190 Some effects of thiamine deficiency on food selection in the rat. Nutr Metab 1970 0.75
191 Zfp30, a KRAB domain containing zinc finger protein gene, maps to mouse chromosome 7. Mamm Genome 1994 0.75
192 Iron fortification of dried skim milk and maize-soy-bean-milk mixture (CSM): availability of iron in Jamaican infant. Br J Nutr 1973 0.75
193 Linkage mapping of murine homolog of the yeast SPT6 gene to MMU11B1. Mamm Genome 1996 0.75
194 Cystic fibrosis linkage exclusion data. Cytogenet Cell Genet 1986 0.75
195 Relationship between total body and muscle respiratory rates in infants with malnutrition. Nature 1968 0.75
196 Manchester exchange 1966/67. Univ Newcastle Tyne Med Gaz 1967 0.75
197 Cloning of cDNA coding for a rat liver protein whose expression is subject to gender-specific regulation by xenobiotics. Biochem Soc Trans 1984 0.75
198 Nutritional status in Jamaica (1968-74). West Indian Med J 1976 0.75
199 Hydronephrosis. 1. Nurs Times 1968 0.75
200 The upstream region of the mouse xist gene contains two ribosomal protein pseudogenes. Mamm Genome 2000 0.75
201 Latest developments in the treatment of severe malnutrition in children. Nutrition 1998 0.75