1
|
Requirement of MIP-1 alpha for an inflammatory response to viral infection.
|
Science
|
1995
|
4.55
|
2
|
Regulation of blood pressure by the type 1A angiotensin II receptor gene.
|
Proc Natl Acad Sci U S A
|
1995
|
3.54
|
3
|
Genetic control of blood pressure and the angiotensinogen locus.
|
Proc Natl Acad Sci U S A
|
1995
|
3.46
|
4
|
Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes.
|
J Clin Invest
|
2001
|
2.86
|
5
|
The prostaglandin receptor EP4 triggers remodelling of the cardiovascular system at birth.
|
Nature
|
1997
|
2.56
|
6
|
Decreased platelet aggregation, increased bleeding time and resistance to thromboembolism in P2Y1-deficient mice.
|
Nat Med
|
1999
|
2.25
|
7
|
Reduced growth, abnormal kidney structure, and type 2 (AT2) angiotensin receptor-mediated blood pressure regulation in mice lacking both AT1A and AT1B receptors for angiotensin II.
|
Proc Natl Acad Sci U S A
|
1998
|
2.17
|
8
|
Receptors for prostaglandin E(2) that regulate cellular immune responses in the mouse.
|
J Clin Invest
|
2001
|
1.99
|
9
|
Angiotensin II regulates cellular immune responses through a calcineurin-dependent pathway.
|
J Clin Invest
|
1999
|
1.80
|
10
|
Nephropathy in human immunodeficiency virus-1 transgenic mice is due to renal transgene expression.
|
J Clin Invest
|
1997
|
1.77
|
11
|
Reproductive failure and reduced blood pressure in mice lacking the EP2 prostaglandin E2 receptor.
|
J Clin Invest
|
1999
|
1.66
|
12
|
Angiotensin II responses in AT1A receptor-deficient mice: a role for AT1B receptors in blood pressure regulation.
|
Am J Physiol
|
1997
|
1.64
|
13
|
The prostaglandin E2 EP1 receptor mediates pain perception and regulates blood pressure.
|
J Clin Invest
|
2001
|
1.60
|
14
|
Divergent functions of angiotensin II receptor isoforms in the brain.
|
J Clin Invest
|
2000
|
1.59
|
15
|
Altered inflammatory responses in leukotriene-deficient mice.
|
Proc Natl Acad Sci U S A
|
1994
|
1.59
|
16
|
In vivo transfer of GPI-linked complement restriction factors from erythrocytes to the endothelium.
|
Science
|
1995
|
1.56
|
17
|
A role for fractalkine and its receptor (CX3CR1) in cardiac allograft rejection.
|
J Immunol
|
2000
|
1.49
|
18
|
Coagulation defects and altered hemodynamic responses in mice lacking receptors for thromboxane A2.
|
J Clin Invest
|
1998
|
1.46
|
19
|
Crosstransplantation of kidneys in normal and Hyp mice. Evidence that the Hyp mouse phenotype is unrelated to an intrinsic renal defect.
|
J Clin Invest
|
1992
|
1.45
|
20
|
Identification of specific EP receptors responsible for the hemodynamic effects of PGE2.
|
Am J Physiol
|
1999
|
1.33
|
21
|
Activation of the murine EP3 receptor for PGE2 inhibits cAMP production and promotes platelet aggregation.
|
J Clin Invest
|
2001
|
1.29
|
22
|
Regulation of sodium balance and blood pressure by the AT(1A) receptor for angiotensin II.
|
Hypertension
|
2000
|
1.26
|
23
|
Renal growth and development in mice lacking AT1A receptors for angiotensin II.
|
Am J Physiol
|
1998
|
1.25
|
24
|
Cardiovascular responses to the isoprostanes iPF(2alpha)-III and iPE(2)-III are mediated via the thromboxane A(2) receptor in vivo.
|
Circulation
|
2000
|
1.21
|
25
|
Failure of spermatogenesis in mouse lines deficient in the Na(+)-K(+)-2Cl(-) cotransporter.
|
J Clin Invest
|
2000
|
1.17
|
26
|
Urinary concentrating function in mice lacking EP3 receptors for prostaglandin E2.
|
Am J Physiol
|
1998
|
1.16
|
27
|
Abnormal water metabolism in mice lacking the type 1A receptor for ANG II.
|
Am J Physiol Renal Physiol
|
2000
|
1.15
|
28
|
Transport of phosphorothioate oligonucleotides in kidney: implications for molecular therapy.
|
Kidney Int
|
1995
|
1.11
|
29
|
Renal function in the AT1A receptor knockout mouse during normal and volume-expanded conditions.
|
Kidney Int
|
1999
|
1.06
|
30
|
Diabetes insipidus in uricase-deficient mice: a model for evaluating therapy with poly(ethylene glycol)-modified uricase.
|
J Am Soc Nephrol
|
2001
|
1.04
|
31
|
Chronic rejection of mouse kidney allografts.
|
Kidney Int
|
1999
|
1.02
|
32
|
Exploring type I angiotensin (AT1) receptor functions through gene targeting.
|
Acta Physiol Scand
|
2004
|
1.01
|
33
|
Insights into the functions of type 1 (AT1) angiotensin II receptors provided by gene targeting.
|
Trends Endocrinol Metab
|
2000
|
0.99
|
34
|
Leukotrienes in renal transplant rejection in rats. Distinct roles for leukotriene B4 and peptidoleukotrienes in the pathogenesis of allograft injury.
|
J Immunol
|
1994
|
0.98
|
35
|
Enhanced renal leukotriene production in murine lupus: role of lipoxygenase metabolites.
|
Kidney Int
|
1991
|
0.97
|
36
|
Immune cells in a mouse airway model of obliterative bronchiolitis.
|
Am J Respir Cell Mol Biol
|
1998
|
0.97
|
37
|
Neuroendocrine effects of dehydration in mice lacking the angiotensin AT1a receptor.
|
Hypertension
|
1999
|
0.96
|
38
|
Effect of anti-CD4 antibody treatment on inflammatory arthritis in MRL-lpr/lpr mice.
|
Clin Immunol Immunopathol
|
1992
|
0.92
|
39
|
Modulation of eicosanoid metabolism in endothelial cells in a xenograft model. Role of cyclooxygenase-2.
|
J Clin Invest
|
1997
|
0.91
|
40
|
Renal vascular reactivity in mice: AngII-induced vasoconstriction in AT1A receptor null mice.
|
J Am Soc Nephrol
|
1999
|
0.90
|
41
|
Systemic autoimmune nephritogenic components induce CSF-1 and TNF-alpha in MRL kidneys.
|
Kidney Int
|
1997
|
0.90
|
42
|
Angiotensin-II-receptors: new targets for antihypertensive therapy.
|
Clin Cardiol
|
1997
|
0.90
|
43
|
Pressure-overload hypertrophy is unabated in mice devoid of AT1A receptors.
|
Am J Physiol
|
1998
|
0.90
|
44
|
Role of EP(2) and EP(3) PGE(2) receptors in control of murine renal hemodynamics.
|
Am J Physiol Heart Circ Physiol
|
2001
|
0.89
|
45
|
Thromboxane receptor blockade reduces renal injury in murine lupus nephritis.
|
Kidney Int
|
1992
|
0.88
|
46
|
Downregulation of T cell receptor expression by CD8(+) lymphocytes in kidney allografts.
|
J Clin Invest
|
1998
|
0.86
|
47
|
Effects of two nonsteroidal anti-inflammatory drugs, indomethacin and oxaprozin, on the kidney.
|
Clin Pharmacol Ther
|
1980
|
0.86
|
48
|
Deficiency of 5-lipoxygenase abolishes sex-related survival differences in MRL-lpr/lpr mice.
|
J Immunol
|
1999
|
0.86
|
49
|
The intragraft CD8+ T cell response in renal allograft rejection in the mouse.
|
Transplantation
|
1996
|
0.84
|
50
|
Deficiency of COX-1 causes natriuresis and enhanced sensitivity to ACE inhibition.
|
Kidney Int
|
2001
|
0.84
|
51
|
Prevention of experimental cyclosporin-induced interstitial fibrosis by losartan and enalapril.
|
Am J Physiol
|
1995
|
0.84
|
52
|
Evidence that renal prostaglandin and thromboxane production is stimulated in chronic cyclosporine nephrotoxicity.
|
Transplantation
|
1987
|
0.83
|
53
|
Enhanced central response to dehydration in mice lacking angiotensin AT(1a) receptors.
|
Am J Physiol Regul Integr Comp Physiol
|
2001
|
0.82
|
54
|
Thromboxane binding and signal transduction in rat glomerular mesangial cells.
|
Am J Physiol
|
1993
|
0.82
|
55
|
A genetic approach for studying the role of thromboxane A2 in the kidney.
|
Kidney Int Suppl
|
1998
|
0.82
|
56
|
A role for leukotrienes in cyclosporine nephrotoxicity.
|
Kidney Int
|
2000
|
0.81
|
57
|
Distribution of binding sites for thromboxane A2 in the mouse kidney.
|
Am J Physiol
|
1996
|
0.81
|
58
|
Transgenic mice as a tool to study the renin-angiotensin system.
|
Contrib Nephrol
|
2001
|
0.81
|
59
|
Thromboxane synthetase inhibition improves function of hydronephrotic rat kidneys.
|
Am J Physiol
|
1986
|
0.81
|
60
|
Altered intragraft immune responses and improved renal function in MHC class II-deficient mouse kidney allografts.
|
Transplantation
|
2000
|
0.81
|
61
|
Characterization of glomerular thromboxane receptors in murine lupus nephritis.
|
J Pharmacol Exp Ther
|
1993
|
0.80
|
62
|
The azaspirane SKF 105685 ameliorates renal allograft rejection in rats.
|
J Am Soc Nephrol
|
1993
|
0.80
|
63
|
Effects of low-dose aspirin therapy on plasma levels of polyunsaturated fatty acids: a preliminary investigation.
|
Am J Perinatol
|
1995
|
0.80
|
64
|
Physiologic role for enhanced renal thromboxane production in murine lupus nephritis.
|
Prostaglandins
|
1991
|
0.80
|
65
|
Functional role of thromboxane production by acutely rejecting renal allografts in rats.
|
J Clin Invest
|
1985
|
0.80
|
66
|
Gene-targeting studies of the renin-angiotensin system: mechanisms of hypertension and cardiovascular disease.
|
Cold Spring Harb Symp Quant Biol
|
2002
|
0.79
|
67
|
Fish oil feeding modulates leukotriene production in murine lupus nephritis.
|
Prostaglandins
|
1994
|
0.79
|
68
|
The allocation of cadaver kidneys for transplantation in the United States: consensus and controversy. ASN Transplant Advisory Group. American Society of Nephrology.
|
J Am Soc Nephrol
|
1999
|
0.79
|
69
|
Rejection of kidney allografts by MHC class I-deficient mice.
|
Transplantation
|
1995
|
0.79
|
70
|
Transplant approach establishes that kidneys are responsible for serum CSF-1 but require a stimulus in MRL-lpr mice.
|
Kidney Int
|
1996
|
0.79
|
71
|
Vasoconstrictor responses in thromboxane receptor knockout mice: tubuloglomerular feedback and ureteral obstruction.
|
Acta Physiol Scand
|
2000
|
0.78
|
72
|
Effects of thromboxane synthase inhibition with CGS 13080 in human cyclosporine nephrotoxicity.
|
Kidney Int
|
1992
|
0.78
|
73
|
Atrial natriuretic peptide-induced changes in renal prostacyclin production in ureteral obstruction.
|
Am J Physiol
|
1990
|
0.78
|
74
|
Deficiency of 5-lipoxygenase accelerates renal allograft rejection in mice.
|
J Immunol
|
2001
|
0.78
|
75
|
Role of platelet activating factor in kidney transplant rejection in the rat.
|
Kidney Int
|
1995
|
0.77
|
76
|
The effects of surgery and acute rejection on glomerular hemodynamics in the transplanted rat kidney.
|
Transplantation
|
1993
|
0.77
|
77
|
Effects of candesartan on angiotensin II-induced renal vasoconstriction in rats and mice.
|
J Am Soc Nephrol
|
1999
|
0.77
|
78
|
Gene targeting: applications in transplantation research.
|
Kidney Int
|
1999
|
0.77
|
79
|
Fas on renal parenchymal cells does not promote autoimmune nephritis in MRL mice.
|
Kidney Int
|
1999
|
0.76
|
80
|
Alterations in renal interleukin-1 production during kidney transplant rejection in the rat. The effects of high-dose methylprednisolone.
|
Transplantation
|
1993
|
0.76
|
81
|
The C-terminus of the thromboxane receptor contributes to coupling and desensitization in a mouse mesangial cell line.
|
J Pharmacol Exp Ther
|
1997
|
0.76
|
82
|
Inducible nitric oxide synthase promotes cytokine expression in cardiac allografts but is not required for efficient rejection.
|
J Heart Lung Transplant
|
1999
|
0.76
|
83
|
A role for T cell co-stimulation in ischemic acute renal failure?
|
Kidney Int
|
1997
|
0.75
|
84
|
Association of chronic thromboxane inhibition with reduced in situ cytotoxic T cell activity in rejecting rat renal allografts.
|
Transplantation
|
1989
|
0.75
|
85
|
Comparison of intravenous digital subtraction angiography and conventional arteriography in defining renal anatomy.
|
Transplantation
|
1988
|
0.75
|
86
|
Late withdrawal of cyclosporine in stable renal transplant recipients.
|
Am J Kidney Dis
|
1995
|
0.75
|
87
|
Circadian rhythms of activity and drinking in mice lacking angiotensin II 1A receptors.
|
Physiol Behav
|
2002
|
0.75
|
88
|
High-protein feeding stimulates renal thromboxane production in rats with streptozocin-induced diabetes.
|
J Lab Clin Med
|
1989
|
0.75
|
89
|
Bilateral native nephrectomy improves renal isograft function in rats.
|
Kidney Int
|
1986
|
0.75
|
90
|
What can knockout mice contribute to an understanding of hypertension?
|
Curr Hypertens Rep
|
2000
|
0.75
|
91
|
Immunologic mechanisms of transplant rejection.
|
Curr Opin Nephrol Hypertens
|
1992
|
0.75
|
92
|
Associations between rat renal allograft function, inflammation, and host immunity.
|
Transplant Proc
|
1987
|
0.75
|
93
|
Effect of low-dose aspirin on thromboxane production and the antihypertensive effect of captopril.
|
J Am Soc Nephrol
|
1993
|
0.75
|
94
|
Genetic manipulation of the renin-angiotensin system.
|
Curr Opin Nephrol Hypertens
|
1999
|
0.75
|
95
|
Evidence that pretransplant donor blood transfusion prevents rat renal allograft dysfunction but not the in situ cellular alloimmune or morphologic manifestations of rejection.
|
Transplantation
|
1988
|
0.75
|
96
|
Modulation of thromboxane receptor activation in rat glomerular mesangial cells.
|
Am J Physiol
|
1994
|
0.75
|