Published in Proc Natl Acad Sci U S A on May 01, 1985
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Lysosomes, pH and the anti-malarial action of chloroquine. Nature (1972) 2.18
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Lysis of Plasmodium falciparum by ferriprotoporphyrin IX and a chloroquine-ferriprotoporphyrin IX complex. Antimicrob Agents Chemother (1982) 1.32
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Mechanism of hemolysis induced by ferriprotoporphyrin IX. J Clin Invest (1981) 1.27
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Characterization of chloroquine plasma protein binding in man. Br J Clin Pharmacol (1983) 1.21
Inhibition of lysosomal phospholipase A and phospholipase C by chloroquine and 4,4'-bis(diethylaminoethoxy) alpha, beta-diethyldiphenylethane. J Biol Chem (1980) 1.14
Lack of cross-resistance to 4-aminoquinolines in chloroquine-resistant Plasmodium falciparum in vitro. J Parasitol (1983) 1.13
Localization of acid phosphatase activity in Plasmodium berghei and P. gallinaceum: an electron microscopic observation. J Parasitol (1971) 0.95
Chloroquine inhibits the degradation of endocytic vesicles in human malaria parasites. Cell Biol Int Rep (1983) 0.92
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A method for the measurement of chloroquine uptake in erythrocytes. Anal Biochem (1980) 0.79
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Matrix metalloproteinase 2 releases active soluble ectodomain of fibroblast growth factor receptor 1. Proc Natl Acad Sci U S A (1996) 2.12
Identification of the acidic compartment of Plasmodium falciparum-infected human erythrocytes as the target of the antimalarial drug chloroquine. EMBO J (1984) 2.11
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Complexity of FGF receptors: genetic basis for structural diversity and functional specificity. FASEB J (1992) 2.00
Characterization of permeation pathways appearing in the host membrane of Plasmodium falciparum infected red blood cells. Mol Biochem Parasitol (1985) 1.94
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Characterization of permeation pathways in the plasma membrane of human erythrocytes infected with early stages of Plasmodium falciparum: association with parasite development. J Cell Physiol (1985) 1.91
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The permeation of organic acids through lecithin bilayers. Resemblance to diffusion in polymers. Biochim Biophys Acta (1975) 1.76
A mouse model for achondroplasia produced by targeting fibroblast growth factor receptor 3. Proc Natl Acad Sci U S A (1999) 1.75
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Stage-dependent effects of chloroquine on Plasmodium falciparum in vitro. J Protozool (1983) 1.70
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An assay of malaria parasite invasion into human erythrocytes. The effects of chemical and enzymatic modification of erythrocyte membrane components. Biochim Biophys Acta (1983) 1.63
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Optimisation of flow cytometric measurement of parasitaemia in plasmodium-infected mice. Int J Parasitol (2000) 1.61
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Extensive transformation of lymphocytes by a mycoplasma organism. Nat New Biol (1973) 1.58
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Iron acquired from transferrin by K562 cells is delivered into a cytoplasmic pool of chelatable iron(II). J Biol Chem (1995) 1.56
Uptake of [3H]chloroquine by drug-sensitive and -resistant strains of the human malaria parasite Plasmodium falciparum. Biochem Pharmacol (1986) 1.53
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Mathematical modelling of the chemotherapy of Plasmodium falciparum malaria with artesunate: postulation of 'dormancy', a partial cytostatic effect of the drug, and its implication for treatment regimens. Parasitology (2000) 1.50
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New permeability pathways induced in membranes of Plasmodium falciparum infected erythrocytes. Mol Biochem Parasitol (1983) 1.45
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Cellular uptake of chloroquine is dependent on binding to ferriprotoporphyrin IX and is independent of NHE activity in Plasmodium falciparum. J Cell Biol (1999) 1.44
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Metabolic interconnection between the human malarial parasite Plasmodium falciparum and its host erythrocyte. Regulation of ATP levels by means of an adenylate translocator and adenylate kinase. J Biol Chem (1989) 1.34
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Mathematical modelling of the within-host dynamics of Plasmodium falciparum. Parasitology (2000) 1.33
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The mitochondrion of Plasmodium falciparum visualized by rhodamine 123 fluorescence. J Protozool (1985) 1.27
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The malaria parasite supplies glutathione to its host cell--investigation of glutathione transport and metabolism in human erythrocytes infected with Plasmodium falciparum. Eur J Biochem (1997) 1.26
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Regional suppression of tumor growth by in vivo transfer of a cDNA encoding a secreted form of the extracellular domain of the flt-1 vascular endothelial growth factor receptor. Hum Gene Ther (1998) 1.19
Alterations in membrane permeability of malaria-infected human erythrocytes are related to the growth stage of the parasite. Biochim Biophys Acta (1982) 1.18
On the mode of action of phlorizin as an antimalarial agent in in vitro cultures of Plasmodium falciparum. Biochem Pharmacol (1987) 1.18
The cellular labile iron pool and intracellular ferritin in K562 cells. Blood (1999) 1.18
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Role of ferritin in the control of the labile iron pool in murine erythroleukemia cells. J Biol Chem (1998) 1.16
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Modelling the chloroquine chemotherapy of falciparum malaria: the value of spacing a split dose. Parasitology (1998) 1.15
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Mathematical modelling of malaria chemotherapy: combining artesunate and mefloquine. Parasitology (2002) 1.13
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Heparin-dependent binding and autophosphorylation of epidermal growth factor (EGF) receptor by heparin-binding EGF-like growth factor but not by EGF. Proc Natl Acad Sci U S A (1994) 1.09
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