Published in J Exp Biol on August 01, 1979
Design principles of biochemical oscillators. Nat Rev Mol Cell Biol (2008) 4.55
Subcellular metabolic transients and mitochondrial redox waves in heart cells. Proc Natl Acad Sci U S A (1998) 2.42
Fluctuations in membrane current driven by intracellular calcium in cardiac Purkinje fibers. Biophys J (1982) 2.20
A Model Based on Receptor Desensitization for Cyclic AMP Signaling in Dictyostelium Cells. Biophys J (1987) 1.79
Voltage-clamp studies of transient inward current and mechanical oscillations induced by ouabain in ferret papillary muscle. J Physiol (1982) 1.64
Mitochondrial oscillations in physiology and pathophysiology. Adv Exp Med Biol (2008) 1.31
Vasomotion: cellular background for the oscillator and for the synchronization of smooth muscle cells. Br J Pharmacol (2005) 1.22
Birhythmicity, chaos, and other patterns of temporal self-organization in a multiply regulated biochemical system. Proc Natl Acad Sci U S A (1982) 1.21
Developmental decisions in Dictyostelium discoideum. Microbiol Rev (1994) 1.13
Current recording from sensory cilia of olfactory receptor cells in situ. I. The neuronal response to cyclic nucleotides. J Gen Physiol (1991) 1.12
Reversible Ca gradients between the subplasmalemma and cytosol differentially activate Ca-dependent Cl currents. J Gen Physiol (1999) 1.08
Impulse responses of automaticity in the Purkinje fiber. Biophys J (1984) 0.93
Control of glycolytic oscillations by temperature. Biophys J (2004) 0.93
Model for receptor-controlled cytosolic calcium oscillations and for external influences on the signal pathway. Biophys J (1993) 0.92
In vivo tissue-wide synchronization of mitochondrial metabolic oscillations. Cell Rep (2014) 0.90
The role of cyclic nucleotides in modulation of the membrane potential of the Schwann cell of squid giant nerve fibre. J Physiol (1985) 0.89
Stimulation of repetitive calcium transients in mouse eggs. J Physiol (1995) 0.88
Effects of theophylline and dibutyryl cyclic adenosine monophosphate on the membrane potential of mouse pancreatic beta-cells. J Physiol (1984) 0.85
Sustained oscillations in extracellular calcium concentrations upon hormonal stimulation of perfused rat liver. Biochem J (1987) 0.85
Single-channel currents trigger action potentials in small cultured hippocampal neurons. Proc Natl Acad Sci U S A (1994) 0.83
Nonlinear current-voltage relationships in cultured macrophages. J Cell Biol (1980) 0.83
Spatial Ca(2+) profiling: decrypting the universal cytosolic Ca(2+) oscillation. J Physiol (2016) 0.83
Traumatic brain injury detection using electrophysiological methods. Front Hum Neurosci (2015) 0.82
Fine tuning of cytosolic Ca (2+) oscillations. F1000Res (2016) 0.78
Ca2+ and cAMP signaling pathways interact to increase the diuretic effect of serotonin in Malpighian tubules of the kissing bug. Focus on "Serotonin triggers cAMP- and PKA-1-mediated intracellular calcium waves in Malpighian tubules of Rhodnius prolixus". Am J Physiol Regul Integr Comp Physiol (2014) 0.76
Making Waves in the Brain: What Are Oscillations, and Why Modulating Them Makes Sense for Brain Injury. Front Syst Neurosci (2016) 0.75
Complex, non-monotonic dose-response curves with multiple maxima: Do we (ever) sample densely enough? Plant Signal Behav (2015) 0.75
Inositol trisphosphate, a novel second messenger in cellular signal transduction. Nature (1984) 25.71
Inositol trisphosphate and diacylglycerol as second messengers. Biochem J (1984) 14.37
Inositol trisphosphate and diacylglycerol: two interacting second messengers. Annu Rev Biochem (1987) 12.04
Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate. Nature (1983) 10.90
Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides. Biochem J (1983) 10.35
Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands. Biochem J (1982) 8.16
Calcium--a life and death signal. Nature (1998) 6.35
Rapid accumulation of inositol trisphosphate reveals that agonists hydrolyse polyphosphoinositides instead of phosphatidylinositol. Biochem J (1983) 6.17
The inositol tris/tetrakisphosphate pathway--demonstration of Ins(1,4,5)P3 3-kinase activity in animal tissues. Nature (1986) 5.41
The second messenger linking receptor activation to internal Ca release in liver. Nature (1984) 3.73
The interaction of cyclic nucleotides and calcium in the control of cellular activity. Adv Cyclic Nucleotide Res (1975) 3.38
Rapid mobilization of Ca2+ from rat insulinoma microsomes by inositol-1,4,5-trisphosphate. Nature (1984) 3.35
The elemental principles of calcium signaling. Cell (1995) 3.18
Inositol trisphosphate formation and calcium mobilization in Swiss 3T3 cells in response to platelet-derived growth factor. Biochem J (1984) 3.07
Minimal model for signal-induced Ca2+ oscillations and for their frequency encoding through protein phosphorylation. Proc Natl Acad Sci U S A (1990) 2.97
Cooking with calcium: the recipes for composing global signals from elementary events. Cell (1997) 2.89
Phosphatidylinositol hydrolysis: a multifunctional transducing mechanism. Mol Cell Endocrinol (1981) 2.81
Relationship between hormonal activation of phosphatidylinositol hydrolysis, fluid secretion and calcium flux in the blowfly salivary gland. Biochem J (1979) 2.70
The organisation and functions of local Ca(2+) signals. J Cell Sci (2001) 2.38
Specificity of inositol phosphate-stimulated Ca2+ mobilization from Swiss-mouse 3T3 cells. Biochem J (1986) 2.30
The AM and FM of calcium signalling. Nature (1997) 2.26
Localization and heterogeneity of agonist-induced changes in cytosolic calcium concentration in single bovine adrenal chromaffin cells from video imaging of fura-2. EMBO J (1989) 2.24
A comparison of fluorescent Ca2+ indicator properties and their use in measuring elementary and global Ca2+ signals. Cell Calcium (2000) 2.21
Specificity of inositol trisphosphate-induced calcium release from permeabilized Swiss-mouse 3T3 cells. Biochem J (1984) 2.18
Spontaneous calcium release from inositol trisphosphate-sensitive calcium stores. Nature (1991) 2.16
Photoreceptor excitation and adaptation by inositol 1,4,5-trisphosphate. Nature (1984) 2.11
Calcium signalling--an overview. Semin Cell Dev Biol (2001) 2.06
Inositol tetrakis- and pentakisphosphates in GH4 cells. J Exp Biol (1985) 2.02
Actions of inositol phosphates on Ca2+ pools in guinea-pig hepatocytes. Biochem J (1984) 2.01
myo-Inositol polyphosphate may be a messenger for visual excitation in Limulus photoreceptors. Nature (1984) 1.96
Cell signalling. A tale of two messengers. Nature (1993) 1.88
Inositol lipids and cell proliferation. Biochim Biophys Acta (1987) 1.84
Reduction of epidermal growth factor receptor affinity by heterologous ligands: evidence for a mechanism involving the breakdown of phosphoinositides and the activation of protein kinase C. Biochem Biophys Res Commun (1984) 1.83
Distribution of two distinct Ca2+-ATPase-like proteins and their relationships to the agonist-sensitive calcium store in adrenal chromaffin cells. Nature (1989) 1.81
Subcellular Ca2+ signals underlying waves and graded responses in HeLa cells. Curr Biol (1996) 1.70
Re-examination of the evidence for low-dimensional, nonlinear structure in the human electroencephalogram. Electroencephalogr Clin Neurophysiol (1996) 1.70
Functional InsP3 receptors that may modulate excitation-contraction coupling in the heart. Curr Biol (2000) 1.68
Inositol 1,4,5-trisphosphate mobilizes intracellular Ca2+ from permeabilized insulin-secreting cells. Biochem J (1984) 1.67
Mitochondrial Ca(2+) uptake depends on the spatial and temporal profile of cytosolic Ca(2+) signals. J Biol Chem (2001) 1.64
Nuclear calcium signalling by individual cytoplasmic calcium puffs. EMBO J (1997) 1.63
Predetermined recruitment of calcium release sites underlies excitation-contraction coupling in rat atrial myocytes. J Physiol (2001) 1.62
Hormone-evoked elementary Ca2+ signals are not stereotypic, but reflect activation of different size channel clusters and variable recruitment of channels within a cluster. J Biol Chem (1998) 1.59
Inhibition of phosphatidylinositol synthesis and the inactivation of calcium entry after prolonged exposure of the blowfly salivary gland to 5-hydroxytryptamine. Biochem J (1979) 1.57
Effects of bombesin and insulin on inositol (1,4,5)trisphosphate and inositol (1,3,4)trisphosphate formation in Swiss 3T3 cells. Cell (1986) 1.55
The regulation of capacitative calcium entry by calcium and protein kinase C in Xenopus oocytes. J Biol Chem (1994) 1.54
Role of calcium and adenosine-3':5'-cyclic monophosphate in controlling fly salivary gland secretion. Proc Natl Acad Sci U S A (1972) 1.51
All-or-nothing Ca2+ mobilization from the intracellular stores of single histamine-stimulated HeLa cells. J Physiol (1992) 1.49
Relationship between secretagogue-induced Ca2+ release and inositol polyphosphate production in permeabilized pancreatic acinar cells. J Biol Chem (1985) 1.45
The thiol reagent, thimerosal, evokes Ca2+ spikes in HeLa cells by sensitizing the inositol 1,4,5-trisphosphate receptor. J Biol Chem (1992) 1.44
Smoothly graded Ca2+ release from inositol 1,4,5-trisphosphate-sensitive Ca2+ stores. J Biol Chem (1994) 1.44
Microscopic properties of elementary Ca2+ release sites in non-excitable cells. Curr Biol (2000) 1.42
Calcium puffs are generic InsP(3)-activated elementary calcium signals and are downregulated by prolonged hormonal stimulation to inhibit cellular calcium responses. J Cell Sci (2001) 1.42
Characterization of elementary Ca2+ release signals in NGF-differentiated PC12 cells and hippocampal neurons. Neuron (1999) 1.39
Expression and function of ryanodine receptors in nonexcitable cells. J Biol Chem (1996) 1.38
The role of 5-hydroxytryptamine and cyclic AMP in the control of fluid secretion by isolated salivary glands. J Exp Biol (1970) 1.36
Luminal Ca2+ promoting spontaneous Ca2+ release from inositol trisphosphate-sensitive stores in rat hepatocytes. J Physiol (1992) 1.35
Relationship between phosphatidylinositol synthesis and recovery of 5-hydroxytryptamine-responsive Ca2+ flux in blowfly salivary glands. Biochem J (1979) 1.34
Excitation and adaptation of Limulus ventral photoreceptors by inositol 1,4,5 triphosphate result from a rise in intracellular calcium. J Gen Physiol (1986) 1.34
Relationship of polyphosphoinositide metabolism to the hormonal activation of the inset salivary gland by 5-hydroxytryptamine. Mol Cell Endocrinol (1984) 1.31
Why are so many biological systems periodic? Prog Neurobiol (1987) 1.30
The role of calcium in fly salivary gland secretion analyzed with the ionophore A-23187. Biochim Biophys Acta (1973) 1.30
Signal-induced Ca2+ oscillations: properties of a model based on Ca(2+)-induced Ca2+ release. Cell Calcium (1991) 1.29
The role of endoplasmic reticulum calcium pumps during cytosolic calcium spiking in pancreatic acinar cells. J Biol Chem (1993) 1.28
Simultaneous measurements of cytosolic calcium and secretion in single bovine adrenal chromaffin cells by fluorescent imaging of fura-2 in cocultured cells. J Cell Biol (1989) 1.27
Fine-structural changes in relation to ion and water transport in the rectal papillae of the blowfly, Calliphora. J Cell Sci (1967) 1.27
Membrane permeability changes during stimulation of isolated salivary glands of Calliphora by 5-hydroxytryptamine. J Physiol (1975) 1.26
Inositol(3,4)bisphosphate and inositol(1,3)bisphosphate in GH4 cells--evidence for complex breakdown of inositol(1,3,4)trisphosphate. Biochem Biophys Res Commun (1987) 1.26
Spatial localization of the stimulus-induced rise in cytosolic Ca2+ in bovine adrenal chromaffin cells. Distinct nicotinic and muscarinic patterns. FEBS Lett (1989) 1.25
Putative capacitative calcium entry channels: expression of Drosophila trp and evidence for the existence of vertebrate homologues. Biochem J (1995) 1.21
Insect salivary glands: stimulation of fluid secretion by 5-hydroxytryptamine and adenosine-3',5'-monophosphate. Science (1968) 1.20
G-protein regulation of capacitative calcium entry may be mediated by protein kinases A and C in Xenopus oocytes. Biochem J (1995) 1.18
Ca2+ entry into PC12 cells initiated by ryanodine receptors or inositol 1,4,5-trisphosphate receptors. Biochem J (1998) 1.18
Inositol 1,4,5-trisphosphorothioate, a stable analogue of inositol trisphosphate which mobilizes intracellular calcium. Biochem J (1989) 1.17
Frequency encoded biochemical regulation is more accurate than amplitude dependent control. J Theor Biol (1981) 1.15
Bovine adrenal chromaffin cells contain an inositol 1,4,5-trisphosphate-insensitive but caffeine-sensitive Ca2+ store that can be regulated by intraluminal free Ca2+. Biochem J (1991) 1.15
Transepithelial potential changes during stimulation of isolated salivary glands with 5-hydroxytryptamine and cyclic AMP. J Exp Biol (1972) 1.15
Extracellular calcium concentration controls the frequency of intracellular calcium spiking independently of inositol 1,4,5-trisphosphate production in HeLa cells. Biochem J (1996) 1.08
The caffeine-sensitive Ca2+ store in bovine adrenal chromaffin cells; an examination of its role in triggering secretion and Ca2+ homeostasis. FEBS Lett (1990) 1.06
The bidirectional flux of cholesterol between cells and lipoproteins. Effects of phospholipid depletion of high density lipoprotein. J Biol Chem (1986) 1.06
DL-myo-inositol 1,4,5-trisphosphorothioate mobilizes intracellular calcium in Swiss 3T3 cells and Xenopus oocytes. Biochem Biophys Res Commun (1988) 1.05
Inositol 1,4,5-trisphosphate may be a signal for f-Met-Leu-Phe-induced intracellular Ca mobilisation in human leucocytes (HL-60 cells). FEBS Lett (1984) 1.03
5-Hydroxytryptamine stimulation of phosphatidylinositol hydrolysis and calcium signalling in the blowfly salivary gland. Cell Calcium (1982) 1.03
Regulation of ion channels by inositol trisphosphate and diacylglycerol. J Exp Biol (1986) 1.02
An atlas of cellular oscillators. J Exp Biol (1979) 1.02
Inositol 1,4,5-trisphosphate-induced Ca2+ release is inhibited by mitochondrial depolarization. Biochem J (2000) 1.02
Quantal Ca2+ release from caffeine-sensitive stores in adrenal chromaffin cells. J Biol Chem (1993) 1.01
Ernst Klenk Lecture, November 1985. Intracellular signalling through inositol trisphosphate and diacylglycerol. Biol Chem Hoppe Seyler (1986) 1.01
Oscillations in calcium-cyclic AMP control loops form the basis of pacemaker activity and other high frequency biological rhythms. J Theor Biol (1977) 1.01
Phosphatidylinositol-hydrolysing enzymes in blowfly salivary glands. Biochem J (1982) 1.01
Capacitative calcium entry is colocalised with calcium release in Xenopus oocytes: evidence against a highly diffusible calcium influx factor. Pflugers Arch (1996) 0.99
The effects of 5-hydroxytryptamine and cyclic AMP on the potential profile across isolated salivary glands. J Exp Biol (1972) 0.98
Regulation of ryanodine receptor opening by lumenal Ca(2+) underlies quantal Ca(2+) release in PC12 cells. J Biol Chem (1999) 0.98
Changes in cyclic AMP and cyclic GMP concentrations during the action of 5-hydroxytryptamine on an insect salivary gland. Biochem J (1980) 0.97
The molecular basis of communication within the cell. Sci Am (1985) 0.97
Separate 5-hydroxytryptamine receptors on the salivary gland of the blowfly are linked to the generation of either cyclic adenosine 3',5'-monophosphate or calcium signals. Br J Pharmacol (1981) 0.96
Cell signalling through phospholipid metabolism. J Cell Sci Suppl (1986) 0.96
Statistical validation of mutual information calculations: comparison of alternative numerical algorithms. Phys Rev E Stat Nonlin Soft Matter Phys (2005) 0.95
Phospholipase C in mouse oocytes: characterization of beta and gamma isoforms and their possible involvement in sperm-induced Ca2+ spiking. Biochem J (1996) 0.95
Subsecond and second changes in inositol polyphosphates in GH4C1 cells induced by thyrotropin-releasing hormone. Biochem J (1987) 0.94