Published in Schweiz Med Wochenschr on January 18, 1986
Actions of insulin-like growth factors. Annu Rev Physiol (1985) 3.80
Insulin-like growth factor I stimulates growth in hypophysectomized rats. Nature (1982) 2.79
Radioimmunological determination of insulinlike growth factors I and II in normal subjects and in patients with growth disorders and extrapancreatic tumor hypoglycemia. J Clin Invest (1981) 2.52
Short-term metabolic effects of recombinant human insulin-like growth factor I in healthy adults. N Engl J Med (1987) 2.00
Insulin-like growth factors I and II: some biological actions and receptor binding characteristics of two purified constituents of nonsuppressible insulin-like activity of human serum. Eur J Biochem (1978) 1.88
Insulin-like growth factors I and II in healthy man. Estimations of half-lives and production rates. Acta Endocrinol (Copenh) (1989) 1.83
Synthesis and secretion of insulin-like growth factor and its binding protein by the perfused rat liver: dependence on growth hormone status. Endocrinology (1983) 1.72
The insulin-like growth factors (IGF) of human serum: chemical and biological characterization and aspects of their possible physiological role. Curr Top Cell Regul (1981) 1.63
Can "big" insulin-like growth factor II in serum of tumor patients account for the development of extrapancreatic tumor hypoglycemia? J Clin Invest (1992) 1.58
Recombinant human insulin-like growth factor I stimulates growth and has distinct effects on organ size in hypophysectomized rats. Proc Natl Acad Sci U S A (1988) 1.55
Insulin-like growth factors in pygmies. The role of puberty in determining final stature. N Engl J Med (1987) 1.55
Binding of nonsuppressible insulinlike activity to human serum. Evidence for a carrier protein. Arch Biochem Biophys (1975) 1.52
Interactions of insulin-like growth factors I and II and multiplication-stimulating activity with receptors and serum carrier proteins. Endocrinology (1980) 1.48
Insulin-like growth factor II in human adrenal pheochromocytomas and Wilms tumors: expression at the mRNA and protein level. Proc Natl Acad Sci U S A (1987) 1.47
Nonsuppressible insulin-like activity and thyroid hormones: major pituitary-dependent sulfation factors for chick embryo cartilage. Proc Natl Acad Sci U S A (1976) 1.45
Improvement of lipid profile in type 2 (non-insulin-dependent) diabetes mellitus by insulin-like growth factor I. Diabetologia (1993) 1.45
Body size parallels insulin-like growth factor I levels but not growth hormone secretory capacity. Acta Endocrinol (Copenh) (1984) 1.43
Nonsuppressible insulin-like activity (NSILA) from human serum: recent accomplishments and their physiologic implications. Metabolism (1978) 1.40
Insulin-like growth factors. Studies in diabetics with and without retinopathy. N Engl J Med (1983) 1.38
Growth restoration of insulin-deficient diabetic rats by recombinant human insulin-like growth factor I. Nature (1986) 1.37
Biological and immunological properties of insulin-like growth factors (IGF) I and II. Clin Endocrinol Metab (1984) 1.35
Acute metabolic effects and half-lives of intravenously administered insulinlike growth factors I and II in normal and hypophysectomized rats. J Clin Invest (1986) 1.35
Effects of recombinant insulin-like growth factor I on insulin secretion and renal function in normal human subjects. Proc Natl Acad Sci U S A (1989) 1.33
Effects and binding of insulin-like growth factor I in the isolated soleus muscle of lean and obese mice: comparison with insulin. Endocrinology (1979) 1.32
Fibroblasts as an experimental tool in metabolic and hormone studies. II. Effects of insulin and nonsuppressible insulin-like activity (NSILA-S) on fibroblasts in culture. Eur J Clin Invest (1973) 1.29
Inhibition of the action of nonsuppressible insulin-like activity on isolated rat fat cells by binding to its carrier protein. J Clin Invest (1979) 1.28
Direct effects of leptin on brown and white adipose tissue. J Clin Invest (1997) 1.22
Non-suppressible insulin-like activity of human serum. I. Physicochemical properties, extraction and partial purification. Biochim Biophys Acta (1966) 1.20
Insulin-like growth factors and insulin: comparative aspects. Diabetologia (1985) 1.20
Effect of trypsin treatment of rat adipocytes on biological effects and binding of insulin and insulin-like growth factors: further evidence for the action of insulin-like growth factors through the insulin receptor. Eur J Biochem (1981) 1.18
Comparison of in vivo effects of insulin-like growth factors I and II and of growth hormone in hypophysectomized rats. Acta Endocrinol (Copenh) (1985) 1.16
Effects of insulin-like growth factor-I on glucose tolerance, insulin levels, and insulin secretion. J Clin Invest (1992) 1.15
Dwarfism in the pygmy. An isolated deficiency of insulin-like growth factor I. N Engl J Med (1981) 1.13
Posttranslational regulation of insulin-like growth factor binding protein-4 in normal and transformed human fibroblasts. Insulin-like growth factor dependence and biological studies. J Clin Invest (1993) 1.13
Crystal structure of a phosphatase-resistant mutant of sporulation response regulator Spo0F from Bacillus subtilis. Structure (1996) 1.13
Activity in fetal bovine serum that stimulates erythroid colony formation in fetal mouse livers is insulinlike growth factor I. J Clin Invest (1985) 1.12
Non-suppressible insulin-like activity and sulphaton activity in serum extracts of normal subjects, acromegalics and pituitary dwarfs. Acta Endocrinol (Copenh) (1976) 1.12
The NSILA-s receptor in liver plasma membranes. Characterization and comparison with the insulin receptor. J Biol Chem (1975) 1.11
Enhanced osteoblast proliferation and collagen gene expression by estradiol. Proc Natl Acad Sci U S A (1988) 1.11
Insulin-like growth factors I and II, prolactin, and insulin in 19 growth hormone-deficient children with excessive, normal, or decreased longitudinal growth after operation for craniopharyngioma. N Engl J Med (1983) 1.10
Insulin and non-suppressible insulin-like activity (NSILA-s): evidence for separate plasma membrane receptor sites. Biochem Biophys Res Commun (1974) 1.09
Regulation of binding proteins for insulin-like growth factors (IGF) in humans. Increased expression of IGF binding protein 2 during IGF I treatment of healthy adults and in patients with extrapancreatic tumor hypoglycemia. J Clin Invest (1990) 1.09
Serum levels of insulin-like growth factor (IGF) and its carrier protein in various metabolic disorders. Acta Endocrinol (Copenh) (1980) 1.09
Insulin-like growth factors in the fed and fasted states. J Clin Endocrinol Metab (1982) 1.08
Differential effects of insulin-like growth factor I and growth hormone on developmental stages of rat growth plate chondrocytes in vivo. J Clin Invest (1994) 1.08
Nonsuppressible insulin-like activity in human serum. 3. Differentiation of two distinct molecules with nonsuppressible ILA. J Clin Invest (1968) 1.07
Insulin-like growth factors (IGF) 1 and 2 in human foetal plasma and relationship to gestational age and foetal size during midpregnancy. Acta Endocrinol (Copenh) (1985) 1.07
Role of muscle insulin-like growth factors in nerve sprouting: suppression of terminal sprouting in paralyzed muscle by IGF-binding protein 4. J Cell Biol (1994) 1.07
Insulin-like growth factor-I improves glucose and lipid metabolism in type 2 diabetes mellitus. J Clin Invest (1992) 1.04
Is extrapancreatic tumor hypoglycemia associated with elevated levels of insulin-like growth factor II? J Clin Endocrinol Metab (1982) 1.03
NSILA-carrier protein abolishes the action of nonsuppressible insulin-like activity (NSILA-S) on perfused rat heart. Diabetologia (1978) 1.03
Repopulation of the atrophied thymus in diabetic rats by insulin-like growth factor I. Proc Natl Acad Sci U S A (1990) 1.03
Preferential enhancement of myoblast differentiation by insulin-like growth factors (IGF I and IGF II) in primary cultures of chicken embryonic cells. FEBS Lett (1983) 1.03
A response regulatory protein with the site of phosphorylation blocked by an arginine interaction: crystal structure of Spo0F from Bacillus subtilis. Biochemistry (1997) 1.02
Stabilizing insulin-like growth factor-I in poly(D,L-lactide-co-glycolide) microspheres. J Control Release (2001) 1.02
Proteolysis of insulin-like growth factors (IGF) and IGF binding proteins by cathepsin D. Endocrinology (1997) 1.01
Insulin regulates insulin-like growth factor I mRNA in rat hepatocytes. Am J Physiol (1991) 1.00
Recombinant human insulin-like growth factor I (rhIGF I) reduces hyperglycaemia in patients with extreme insulin resistance. Diabetologia (1991) 0.99
Nonsuppressible insulinlike activity of human serum: purification, physiochemical and biological properties and its relation to total serum ILA. Recent Prog Horm Res (1967) 0.99
Recombinant human insulin-like growth factor I induces its own specific carrier protein in hypophysectomized and diabetic rats. Proc Natl Acad Sci U S A (1989) 0.99
Molecular cloning of a new human insulin-like growth factor binding protein. Biochem Biophys Res Commun (1991) 0.98
Human fetal and adult chondrocytes. Effect of insulinlike growth factors I and II, insulin, and growth hormone on clonal growth. J Clin Invest (1986) 0.98
Hepatic and pulmonary metastases from a meningeal hemangiopericytoma and severe hypoglycemia due to abnormal secretion of insulin-like growth factor: a case report. Cancer (1999) 0.97
Specific binding of nonsupressible insulinlike activity to chicken embryo fibroblasts and to a solubilized fibroblast receptor. Arch Biochem Biophys (1975) 0.97
Insulin-like growth factor I stimulates myofibril development and decreases smooth muscle alpha-actin of adult cardiomyocytes. Proc Natl Acad Sci U S A (1994) 0.97