Published in J Neurosci on March 01, 1986
Dopamine in motivational control: rewarding, aversive, and alerting. Neuron (2010) 6.26
Input-specific control of reward and aversion in the ventral tegmental area. Nature (2012) 4.60
The rostromedial tegmental nucleus (RMTg), a GABAergic afferent to midbrain dopamine neurons, encodes aversive stimuli and inhibits motor responses. Neuron (2009) 4.12
The habenula: from stress evasion to value-based decision-making. Nat Rev Neurosci (2010) 3.31
Representation of negative motivational value in the primate lateral habenula. Nat Neurosci (2008) 3.29
The mesopontine rostromedial tegmental nucleus: A structure targeted by the lateral habenula that projects to the ventral tegmental area of Tsai and substantia nigra compacta. J Comp Neurol (2009) 2.83
The globus pallidus sends reward-related signals to the lateral habenula. Neuron (2008) 2.81
A neural signature of hierarchical reinforcement learning. Neuron (2011) 2.49
The neurobiology and genetics of impulse control disorders: relationships to drug addictions. Biochem Pharmacol (2007) 2.22
Negative reward signals from the lateral habenula to dopamine neurons are mediated by rostromedial tegmental nucleus in primates. J Neurosci (2011) 2.19
Habenula: crossroad between the basal ganglia and the limbic system. J Neurosci (2008) 2.07
Obesity and addiction: neurobiological overlaps. Obes Rev (2012) 1.99
Mapping of olfactory memory circuits: region-specific c-fos activation after odor-reward associative learning or after its retrieval. Learn Mem (2002) 1.85
Basal Ganglia disorders associated with imbalances in the striatal striosome and matrix compartments. Front Neuroanat (2011) 1.85
Reward, addiction, withdrawal to nicotine. Annu Rev Neurosci (2011) 1.83
Fos activation of selective afferents to ventral tegmental area during cue-induced reinstatement of cocaine seeking in rats. J Neurosci (2012) 1.79
Mesolimbic dopamine neurons in the brain reward circuit mediate susceptibility to social defeat and antidepressant action. J Neurosci (2010) 1.75
Cocaine drives aversive conditioning via delayed activation of dopamine-responsive habenular and midbrain pathways. J Neurosci (2013) 1.73
The habenular nuclei: a conserved asymmetric relay station in the vertebrate brain. Philos Trans R Soc Lond B Biol Sci (2009) 1.72
Reward and aversion in a heterogeneous midbrain dopamine system. Neuropharmacology (2013) 1.67
A unique population of ventral tegmental area neurons inhibits the lateral habenula to promote reward. Neuron (2013) 1.66
A pallidus-habenula-dopamine pathway signals inferred stimulus values. J Neurophysiol (2010) 1.60
The inhibitory influence of the lateral habenula on midbrain dopamine cells: ultrastructural evidence for indirect mediation via the rostromedial mesopontine tegmental nucleus. J Comp Neurol (2011) 1.59
Lateral habenula projections to dopamine and GABA neurons in the rat ventral tegmental area. Eur J Neurosci (2009) 1.53
The effects of tryptophan depletion on neural responses to emotional words in remitted depression. Biol Psychiatry (2009) 1.50
Addiction science: Uncovering neurobiological complexity. Neuropharmacology (2013) 1.50
Lateral habenula neurons signal errors in the prediction of reward information. Nat Neurosci (2011) 1.48
Distinct tonic and phasic anticipatory activity in lateral habenula and dopamine neurons. Neuron (2010) 1.44
Braking dopamine systems: a new GABA master structure for mesolimbic and nigrostriatal functions. J Neurosci (2012) 1.42
A food predictive cue must be attributed with incentive salience for it to induce c-fos mRNA expression in cortico-striatal-thalamic brain regions. Neuroscience (2011) 1.41
Differential tonic influence of lateral habenula on prefrontal cortex and nucleus accumbens dopamine release. Eur J Neurosci (2008) 1.36
Schizophrenia in translation: the presence of absence: habenular regulation of dopamine neurons and the encoding of negative outcomes. Schizophr Bull (2006) 1.33
Effects of drugs of abuse on putative rostromedial tegmental neurons, inhibitory afferents to midbrain dopamine cells. Neuropsychopharmacology (2010) 1.29
Neuronal Reward and Decision Signals: From Theories to Data. Physiol Rev (2015) 1.24
Electrical stimulation of the lateral habenula produces enduring inhibitory effect on cocaine seeking behavior. Neuropharmacology (2010) 1.19
Distinct patterns of neuronal inputs and outputs of the juxtaparaventricular and suprafornical regions of the lateral hypothalamic area in the male rat. Brain Res Rev (2010) 1.18
Multiple timescales of memory in lateral habenula and dopamine neurons. Neuron (2010) 1.17
Inhibitory inputs from rostromedial tegmental neurons regulate spontaneous activity of midbrain dopamine cells and their responses to drugs of abuse. Neuropsychopharmacology (2011) 1.14
Functional implications of glutamatergic projections to the ventral tegmental area. Rev Neurosci (2008) 1.11
DREADDing the lateral habenula: a review of methodological approaches for studying lateral habenula function. Brain Res (2012) 1.10
Optogenetic modulation of neural circuits that underlie reward seeking. Biol Psychiatry (2011) 1.09
Phylogeny and ontogeny of the habenular structure. Front Neurosci (2011) 1.08
Electrical stimulation of the lateral habenula produces an inhibitory effect on sucrose self-administration. Neuropharmacology (2010) 1.06
The place of dopamine in the cortico-basal ganglia circuit. Neuroscience (2014) 1.05
An excitatory synapse hypothesis of depression. Trends Neurosci (2015) 1.05
Silencing the critics: understanding the effects of cocaine sensitization on dorsolateral and ventral striatum in the context of an actor/critic model. Front Neurosci (2008) 1.03
Evolutionary conservation of the habenular nuclei and their circuitry controlling the dopamine and 5-hydroxytryptophan (5-HT) systems. Proc Natl Acad Sci U S A (2011) 1.02
α3β4 nicotinic acetylcholine receptors in the medial habenula modulate the mesolimbic dopaminergic response to acute nicotine in vivo. Neuropharmacology (2012) 1.01
Dopamine reward prediction-error signalling: a two-component response. Nat Rev Neurosci (2016) 1.01
Brain regions mediating alpha3beta4 nicotinic antagonist effects of 18-MC on methamphetamine and sucrose self-administration. Eur J Pharmacol (2008) 0.99
Brain regions mediating α3β4 nicotinic antagonist effects of 18-MC on nicotine self-administration. Eur J Pharmacol (2011) 0.98
Mechanistic insights into nicotine withdrawal. Biochem Pharmacol (2011) 0.98
The role of dopamine in the context of aversive stimuli with particular reference to acoustically signaled avoidance learning. Front Neurosci (2012) 0.97
Independent circuits in the basal ganglia for the evaluation and selection of actions. Proc Natl Acad Sci U S A (2013) 0.96
Distinct midbrain and habenula pathways are involved in processing aversive events in humans. J Neurosci (2015) 0.94
Stimulus-response and response-outcome learning mechanisms in the striatum. Behav Brain Res (2008) 0.93
Medial prefrontal cortex inversely regulates toluene-induced changes in markers of synaptic plasticity of mesolimbic dopamine neurons. J Neurosci (2013) 0.92
Synaptic and cellular profile of neurons in the lateral habenula. Front Hum Neurosci (2013) 0.92
Lesions of the fasciculus retroflexus alter footshock-induced cFos expression in the mesopontine rostromedial tegmental area of rats. PLoS One (2013) 0.90
Norepinephrine activates dopamine D4 receptors in the rat lateral habenula. J Neurosci (2015) 0.90
Mesopontine rostromedial tegmental nucleus neurons projecting to the dorsal raphe and pedunculopontine tegmental nucleus: psychostimulant-elicited Fos expression and collateralization. Brain Struct Funct (2011) 0.90
The mesopontine rostromedial tegmental nucleus: an integrative modulator of the reward system. Basal Ganglia (2011) 0.90
Unmasking the mysteries of the habenula in pain and analgesia. Prog Neurobiol (2012) 0.88
Inactivation of the lateral habenula reduces anxiogenic behavior and cocaine seeking under conditions of heightened stress. Pharmacol Biochem Behav (2013) 0.88
Electrical stimulation of the primate lateral habenula suppresses saccadic eye movement through a learning mechanism. PLoS One (2011) 0.88
Lateral Hypothalamic Area Glutamatergic Neurons and Their Projections to the Lateral Habenula Regulate Feeding and Reward. J Neurosci (2016) 0.87
Stimulation of midbrain dopaminergic structures modifies firing rates of rat lateral habenula neurons. PLoS One (2012) 0.87
Dopamine D4 receptor excitation of lateral habenula neurons via multiple cellular mechanisms. J Neurosci (2013) 0.86
Habenula Lesions Reveal that Multiple Mechanisms Underlie Dopamine Prediction Errors. Neuron (2015) 0.86
Multiplexed neurochemical signaling by neurons of the ventral tegmental area. J Chem Neuroanat (2016) 0.85
Hyperactivation of the habenula as a link between depression and sleep disturbance. Front Hum Neurosci (2013) 0.85
Electrical stimulation of lateral habenula during learning: frequency-dependent effects on acquisition but not retrieval of a two-way active avoidance response. PLoS One (2013) 0.84
Lesion of the rostromedial tegmental nucleus increases voluntary ethanol consumption and accelerates extinction of ethanol-induced conditioned taste aversion. Psychopharmacology (Berl) (2016) 0.84
Sex-specific Esr2 mRNA expression in the rat hypothalamus and amygdala is altered by neonatal bisphenol A exposure. Reproduction (2014) 0.84
The neural basis of deception in strategic interactions. Front Behav Neurosci (2015) 0.82
Diverse sources of reward value signals in the basal ganglia nuclei transmitted to the lateral habenula in the monkey. Front Hum Neurosci (2013) 0.82
Volatile solvents as drugs of abuse: focus on the cortico-mesolimbic circuitry. Neuropsychopharmacology (2013) 0.82
Building an asymmetric brain: development of the zebrafish epithalamus. Semin Cell Dev Biol (2008) 0.82
Lateral Habenula determines long-term storage of aversive memories. Front Behav Neurosci (2014) 0.81
Response of striosomal opioid signaling to dopamine depletion in 6-hydroxydopamine-lesioned rat model of Parkinson's disease: a potential compensatory role. Front Cell Neurosci (2013) 0.81
Negative motivational control of saccadic eye movement by the lateral habenula. Prog Brain Res (2008) 0.81
Habenula functional resting-state connectivity in pediatric CRPS. J Neurophysiol (2013) 0.81
Increased excitability of lateral habenula neurons in adolescent rats following cocaine self-administration. Int J Neuropsychopharmacol (2014) 0.80
Dopaminergic circuitry and risk/reward decision making: implications for schizophrenia. Schizophr Bull (2014) 0.79
Ongoing behavioral state information signaled in the lateral habenula guides choice flexibility in freely moving rats. Front Behav Neurosci (2015) 0.79
Metabotropic glutamate 7 (mGlu7) receptor: a target for medication development for the treatment of cocaine dependence. Neuropharmacology (2012) 0.79
A sensitizing D-amphetamine dose regimen induces long-lasting spinophilin and VGLUT1 protein upregulation in the rat diencephalon. Neurosci Lett (2009) 0.78
Resting-state functional connectivity of the human habenula in healthy individuals: Associations with subclinical depression. Hum Brain Mapp (2016) 0.77
Role of nicotinic receptors in the lateral habenula in the attenuation of amphetamine-induced prepulse inhibition deficits of the acoustic startle response in rats. Psychopharmacology (Berl) (2015) 0.77
Affective and cognitive prefrontal cortex projections to the lateral habenula in humans. Front Hum Neurosci (2014) 0.76
Habenula-Induced Inhibition of Midbrain Dopamine Neurons Is Diminished by Lesions of the Rostromedial Tegmental Nucleus. J Neurosci (2017) 0.76
Circadian influences on dopamine circuits of the brain: regulation of striatal rhythms of clock gene expression and implications for psychopathology and disease. F1000Res (2016) 0.76
Functional magnetic resonance imaging in awake transgenic fragile X rats: evidence of dysregulation in reward processing in the mesolimbic/habenular neural circuit. Transl Psychiatry (2016) 0.75
Functional evidence for a direct excitatory projection from the lateral habenula to the ventral tegmental area in the rat. J Neurophysiol (2016) 0.75
Reward prediction error signals by reticular formation neurons. Learn Mem (2008) 0.75
Can the Lateral Habenula Crack the Serotonin Code? Front Synaptic Neurosci (2016) 0.75
The Lateral Habenula Circuitry: Reward Processing and Cognitive Control. J Neurosci (2016) 0.75
Lateral Habenula Involvement in Impulsive Cocaine Seeking. Neuropsychopharmacology (2016) 0.75
Excitation of lateral habenula neurons as a neural mechanism underlying ethanol-induced conditioned taste aversion. J Physiol (2016) 0.75
Calcium-dependent paired-pulse facilitation of miniature EPSC frequency accompanies depression of EPSCs at hippocampal synapses in culture. J Neurosci (1996) 1.51
Increased coupling and altered glutamate transport currents in astrocytes following kainic-acid-induced status epilepticus. Neurobiol Dis (2010) 1.00
Electrophysiological properties of neurons in the lateral habenula nucleus: an in vitro study. J Neurophysiol (1988) 0.97
Presence of mRNA for glutamic acid decarboxylase in both excitatory and inhibitory neurons. Proc Natl Acad Sci U S A (1996) 0.92
Assessing the risks of exposures to multiple chemicals with a common mechanism of toxicity: how to cumulate? Regul Toxicol Pharmacol (2000) 0.89
In vitro electrophysiology of neurons in the lateral dorsal tegmental nucleus. Brain Res Bull (1989) 0.87
Contributions of astrocytes to epileptogenesis following status epilepticus: opportunities for preventive therapy? Neurochem Int (2012) 0.85
Kainate and electrolytic lesions of the lateral habenula: effect on avoidance responses. Physiol Behav (1986) 0.84
Differential contribution of kainate receptors to excitatory postsynaptic currents in superficial layer neurons of the rat medial entorhinal cortex. Neuroscience (2007) 0.83
Different patterns of synaptic transmission revealed between hippocampal CA3 stratum oriens and stratum lucidum interneurons and their pyramidal cell targets. Neuroscience (2003) 0.79
Reduction of striatal dopaminergic neurotransmission elevates striatal proenkephalin mRNA. Eur J Pharmacol (1986) 0.79
Characterization of desensitization in recombinant N-methyl-D-aspartate receptors: comparison with native receptors in cultured hippocampal neurons. Brain Res Mol Brain Res (1998) 0.78
Electrophysiological evidence for a dopaminergic action of LSD: depression of unit activity in the substantia nigra of the rat. Life Sci (1977) 0.76
Reduction of dopamine receptor activity differentially alters striatal neuropeptide mRNA levels. Adv Exp Med Biol (1987) 0.75
Comparative effects of hallucinogenic drugs on behavior of the cat. Commun Psychopharmacol (1977) 0.75
A call for help: networking. Nurs Manage (1994) 0.75
"We're the world's highest-paid babysitters". RN (1985) 0.75
Dopamine agonist pretreatment alters LSD's electrophysiological action from dopamine agonists to antagonist. Life Sci (1978) 0.75
Evaluation of a method used to test for potential toxicity of carpet emissions. Food Chem Toxicol (1994) 0.75
Acute and subchronic neurotoxicological evaluation of tetrahydrofuran by inhalation in rats. Drug Chem Toxicol (2001) 0.75
A New Salmonella Type: Salmonella papuana. J Bacteriol (1945) 0.75