Published in J Neurosci on September 19, 2012
Distinct extended amygdala circuits for divergent motivational states. Nature (2013) 2.88
The reinstatement model of drug relapse: recent neurobiological findings, emerging research topics, and translational research. Psychopharmacology (Berl) (2013) 2.01
Designer receptors show role for ventral pallidum input to ventral tegmental area in cocaine seeking. Nat Neurosci (2014) 1.40
Optogenetic evidence that pallidal projections, not nigral projections, from the nucleus accumbens core are necessary for reinstating cocaine seeking. J Neurosci (2013) 1.12
Ghrelin acts as an interface between physiological state and phasic dopamine signaling. J Neurosci (2014) 1.07
The ventral pallidum: Subregion-specific functional anatomy and roles in motivated behaviors. Prog Neurobiol (2015) 1.06
Differential roles of medial prefrontal subregions in the regulation of drug seeking. Brain Res (2014) 0.97
Emerging role for corticotropin releasing factor signaling in the bed nucleus of the stria terminalis at the intersection of stress and reward. Front Psychiatry (2013) 0.97
Optogenetic strategies to investigate neural circuitry engaged by stress. Behav Brain Res (2013) 0.91
Using c-fos to study neuronal ensembles in corticostriatal circuitry of addiction. Brain Res (2014) 0.86
Dopamine D4 receptor excitation of lateral habenula neurons via multiple cellular mechanisms. J Neurosci (2013) 0.86
The Nucleus Accumbens: Mechanisms of Addiction across Drug Classes Reflect the Importance of Glutamate Homeostasis. Pharmacol Rev (2016) 0.86
A critical role of lateral hypothalamus in context-induced relapse to alcohol seeking after punishment-imposed abstinence. J Neurosci (2014) 0.85
Dorsal and ventral streams: the distinct role of striatal subregions in the acquisition and performance of goal-directed actions. Neurobiol Learn Mem (2013) 0.85
Reacquisition of cocaine conditioned place preference and its inhibition by previous social interaction preferentially affect D1-medium spiny neurons in the accumbens corridor. Front Behav Neurosci (2014) 0.83
The Ergogenic Effect of Amphetamine. Temperature (Austin) (2014) 0.83
Cocaine dysregulates opioid gating of GABA neurotransmission in the ventral pallidum. J Neurosci (2014) 0.83
Attenuation of saccharin-seeking in rats by orexin/hypocretin receptor 1 antagonist. Psychopharmacology (Berl) (2013) 0.82
Increased conditioned place preference for cocaine in high anxiety related behavior (HAB) mice is associated with an increased activation in the accumbens corridor. Front Behav Neurosci (2014) 0.82
DREADDS: Use and application in behavioral neuroscience. Behav Neurosci (2016) 0.80
Binge-like consumption of ethanol and other salient reinforcers is blocked by orexin-1 receptor inhibition and leads to a reduction of hypothalamic orexin immunoreactivity. Alcohol Clin Exp Res (2015) 0.80
The bed nucleus of the stria terminalis regulates ethanol-seeking behavior in mice. Neuropharmacology (2015) 0.80
Maternally responsive neurons in the bed nucleus of the stria terminalis and medial preoptic area: Putative circuits for regulating anxiety and reward. Front Neuroendocrinol (2015) 0.79
Effects of social defeat on dopamine neurons in the ventral tegmental area in male and female California mice. Eur J Neurosci (2015) 0.78
Cocaine self-administration and extinction alter medullary noradrenergic and limbic forebrain cFos responses to acute, noncontingent cocaine injections in adult rats. Neuroscience (2014) 0.78
Orexin/hypocretin neuron activation is correlated with alcohol seeking and preference in a topographically specific manner. Eur J Neurosci (2016) 0.77
Integration of reward signalling and appetite regulating peptide systems in the control of food-cue responses. Br J Pharmacol (2015) 0.77
Ventral Tegmental Area Afferents and Drug-Dependent Behaviors. Front Psychiatry (2016) 0.77
Dynamic changes in extracellular release of GABA and glutamate in the lateral septum during social play behavior in juvenile rats: Implications for sex-specific regulation of social play behavior. Neuroscience (2015) 0.76
Cocaine Seeking During Initial Abstinence Is Driven by Noradrenergic and Serotonergic Signaling in Hippocampus in a Sex-Dependent Manner. Neuropsychopharmacology (2016) 0.76
Recruitment of multiple pathways to ventral tegmental area during cocaine-seeking behavior. J Neurosci (2013) 0.75
Prelimbic to Accumbens Core Pathway Is Recruited in a Dopamine-Dependent Manner to Drive Cued Reinstatement of Cocaine Seeking. J Neurosci (2016) 0.75
Oxytocin Acts in Nucleus Accumbens to Attenuate Methamphetamine Seeking and Demand. Biol Psychiatry (2016) 0.75
Pharmacological modulation of lateral habenular dopamine D2 receptors alters the anxiogenic response to cocaine in a runway model of drug self-administration. Behav Brain Res (2016) 0.75
Ethanol-seeking behavior is expressed directly through an extended amygdala to midbrain neural circuit. Neurobiol Learn Mem (2016) 0.75
Frontostriatal Circuit Dynamics Correlate with Cocaine Cue-Evoked Behavioral Arousal during Early Abstinence. eNeuro (2016) 0.75
The bed nucleus of the stria terminalis in drug-associated behavior and affect: A circuit-based perspective. Neuropharmacology (2017) 0.75
Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell (1998) 12.66
The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity. Proc Natl Acad Sci U S A (1998) 9.32
The debate over dopamine's role in reward: the case for incentive salience. Psychopharmacology (Berl) (2006) 9.18
Positive reinforcement produced by electrical stimulation of septal area and other regions of rat brain. J Comp Physiol Psychol (1954) 6.65
Dopamine reward circuitry: two projection systems from the ventral midbrain to the nucleus accumbens-olfactory tubercle complex. Brain Res Rev (2007) 6.36
Lateral habenula as a source of negative reward signals in dopamine neurons. Nature (2007) 6.32
A role for lateral hypothalamic orexin neurons in reward seeking. Nature (2005) 5.41
Behavioral dopamine signals. Trends Neurosci (2007) 4.79
The role of nucleus accumbens dopamine in motivated behavior: a unifying interpretation with special reference to reward-seeking. Brain Res Brain Res Rev (1999) 4.77
Effort-related functions of nucleus accumbens dopamine and associated forebrain circuits. Psychopharmacology (Berl) (2007) 4.73
The rostromedial tegmental nucleus (RMTg), a GABAergic afferent to midbrain dopamine neurons, encodes aversive stimuli and inhibits motor responses. Neuron (2009) 4.12
Two types of neurone in the rat ventral tegmental area and their synaptic inputs. J Physiol (1992) 3.98
Cortico-Basal Ganglia reward network: microcircuitry. Neuropsychopharmacology (2010) 3.81
Dopamine operates as a subsecond modulator of food seeking. J Neurosci (2004) 3.79
Dopamine signals for reward value and risk: basic and recent data. Behav Brain Funct (2010) 3.42
Brain circuitry and the reinstatement of cocaine-seeking behavior. Psychopharmacology (Berl) (2003) 3.24
Hedonic hot spot in nucleus accumbens shell: where do mu-opioids cause increased hedonic impact of sweetness? J Neurosci (2005) 3.10
Role for hypocretin in mediating stress-induced reinstatement of cocaine-seeking behavior. Proc Natl Acad Sci U S A (2005) 3.05
Projections from the rat prefrontal cortex to the ventral tegmental area: target specificity in the synaptic associations with mesoaccumbens and mesocortical neurons. J Neurosci (2000) 2.91
Limbic and motor circuitry underlying footshock-induced reinstatement of cocaine-seeking behavior. J Neurosci (2004) 2.87
The mesopontine rostromedial tegmental nucleus: A structure targeted by the lateral habenula that projects to the ventral tegmental area of Tsai and substantia nigra compacta. J Comp Neurol (2009) 2.83
Glutamatergic afferents of the ventral tegmental area in the rat. J Neurosci (2007) 2.80
Efferent connections of the habenular nuclei in the rat. J Comp Neurol (1979) 2.65
Stimulation of the lateral habenula inhibits dopamine-containing neurons in the substantia nigra and ventral tegmental area of the rat. J Neurosci (1986) 2.63
Specificity in the projection patterns of accumbal core and shell in the rat. Neuroscience (1991) 2.58
New perspectives in basal forebrain organization of special relevance for neuropsychiatric disorders: the striatopallidal, amygdaloid, and corticopetal components of substantia innominata. Neuroscience (1988) 2.50
Linking context with reward: a functional circuit from hippocampal CA3 to ventral tegmental area. Science (2011) 2.48
Drug addiction and the memory systems of the brain. Ann N Y Acad Sci (2008) 2.36
Positive and negative motivation in nucleus accumbens shell: bivalent rostrocaudal gradients for GABA-elicited eating, taste "liking"/"disliking" reactions, place preference/avoidance, and fear. J Neurosci (2002) 2.30
Anatomical substrates of orexin-dopamine interactions: lateral hypothalamic projections to the ventral tegmental area. Neuroscience (2002) 2.26
Afferents of the ventral tegmental area in the rat-anatomical substratum for integrative functions. J Comp Neurol (2005) 2.22
Dissociation in conditioned dopamine release in the nucleus accumbens core and shell in response to cocaine cues and during cocaine-seeking behavior in rats. J Neurosci (2000) 2.19
Negative reward signals from the lateral habenula to dopamine neurons are mediated by rostromedial tegmental nucleus in primates. J Neurosci (2011) 2.19
A role for the bed nucleus of the stria terminalis, but not the amygdala, in the effects of corticotropin-releasing factor on stress-induced reinstatement of cocaine seeking. J Neurosci (1999) 2.16
Disentangling pleasure from incentive salience and learning signals in brain reward circuitry. Proc Natl Acad Sci U S A (2011) 2.09
Prelude to passion: limbic activation by "unseen" drug and sexual cues. PLoS One (2008) 2.07
A PHA-L analysis of ascending projections of the dorsal raphe nucleus in the rat. J Comp Neurol (1991) 2.01
Connections of the rat lateral septal complex. Brain Res Brain Res Rev (1997) 2.00
Activation of ventral tegmental area cells by the bed nucleus of the stria terminalis: a novel excitatory amino acid input to midbrain dopamine neurons. J Neurosci (2002) 2.00
The ventral tegmental area is required for the behavioral and nucleus accumbens neuronal firing responses to incentive cues. J Neurosci (2004) 1.97
General and outcome-specific forms of Pavlovian-instrumental transfer: the effect of shifts in motivational state and inactivation of the ventral tegmental area. Eur J Neurosci (2007) 1.89
The connections of the septal region in the rat. J Comp Neurol (1979) 1.85
Limbic-striatal memory systems and drug addiction. Neurobiol Learn Mem (2002) 1.82
Distribution of pontomesencephalic cholinergic neurons projecting to substantia nigra differs significantly from those projecting to ventral tegmental area. J Neurosci (1995) 1.81
Extended amygdala and basal forebrain. Ann N Y Acad Sci (2003) 1.80
Fear and feeding in the nucleus accumbens shell: rostrocaudal segregation of GABA-elicited defensive behavior versus eating behavior. J Neurosci (2001) 1.75
Self-stimulation of the brain; its use to study local effects of hunger, sex, and drugs. Science (1958) 1.72
Intrinsic GABAergic neurons in the rat central extended amygdala. J Comp Neurol (1993) 1.68
Orexin/hypocretin signaling at the orexin 1 receptor regulates cue-elicited cocaine-seeking. Eur J Neurosci (2009) 1.67
Hypothesis-driven structural connectivity analysis supports network over hierarchical model of brain architecture. Proc Natl Acad Sci U S A (2010) 1.66
A role for conditioned ventral tegmental glutamate release in cocaine seeking. J Neurosci (2007) 1.65
Common biology of craving across legal and illegal drugs - a quantitative meta-analysis of cue-reactivity brain response. Eur J Neurosci (2011) 1.62
Glutamate motivational ensembles in nucleus accumbens: rostrocaudal shell gradients of fear and feeding. Eur J Neurosci (2003) 1.62
The inhibitory influence of the lateral habenula on midbrain dopamine cells: ultrastructural evidence for indirect mediation via the rostromedial mesopontine tegmental nucleus. J Comp Neurol (2011) 1.59
Efferent connections and nigral afferents of the nucleus accumbens septi in the rat. Neuroscience (1978) 1.57
Afferent projections to the ventral tegmental area of Tsai and interfascicular nucleus: a horseradish peroxidase study in the rat. J Comp Neurol (1979) 1.55
Dynamic computation of incentive salience: "wanting" what was never "liked". J Neurosci (2009) 1.55
Self-infusion of GABA(A) antagonists directly into the ventral tegmental area and adjacent regions. Behav Neurosci (1997) 1.54
Lateral habenula projections to dopamine and GABA neurons in the rat ventral tegmental area. Eur J Neurosci (2009) 1.53
Glutamatergic inputs from the pedunculopontine nucleus to midbrain dopaminergic neurons in primates: Phaseolus vulgaris-leucoagglutinin anterograde labeling combined with postembedding glutamate and GABA immunohistochemistry. J Comp Neurol (1996) 1.51
GABA and enkephalin projection from the nucleus accumbens and ventral pallidum to the ventral tegmental area. Neuroscience (1993) 1.50
Organization of the output of the ventral striatopallidal system in the rat: ventral pallidal efferents. Neuroscience (1993) 1.47
Cocaine-induced reinstatement requires endogenous stimulation of mu-opioid receptors in the ventral pallidum. J Neurosci (2005) 1.41
Potent regulation of midbrain dopamine neurons by the bed nucleus of the stria terminalis. J Neurosci (2001) 1.40
Nucleus accumbens medium spiny neurons target non-dopaminergic neurons in the ventral tegmental area. J Neurosci (2011) 1.34
Efferent projections of the nucleus accumbens in the rat with special reference to subdivision of the nucleus: biotinylated dextran amine study. Brain Res (1998) 1.33
Glutamatergic axons from the lateral habenula mainly terminate on GABAergic neurons of the ventral midbrain. Neuroscience (2010) 1.32
Specificity in the efferent projections of the nucleus accumbens in the rat: comparison of the rostral pole projection patterns with those of the core and shell. J Comp Neurol (1993) 1.32
Phasic dopamine release in appetitive behaviors and drug addiction. Curr Drug Abuse Rev (2009) 1.30
The melanin-concentrating hormone system modulates cocaine reward. Proc Natl Acad Sci U S A (2009) 1.30
Orexin/hypocretin is necessary for context-driven cocaine-seeking. Neuropharmacology (2009) 1.29
Distinct sites of opiate reward and aversion within the midbrain identified using a herpes simplex virus vector expressing GluR1. J Neurosci (2000) 1.28
Chemoarchitecture of the rat lateral septal nucleus. Brain Res Brain Res Rev (1997) 1.26
Multiple roles for orexin/hypocretin in addiction. Prog Brain Res (2012) 1.26
A top-down perspective on dopamine, motivation and memory. Pharmacol Biochem Behav (2007) 1.25
Reinstatement of cocaine seeking by hypocretin (orexin) in the ventral tegmental area: independence from the local corticotropin-releasing factor network. Biol Psychiatry (2009) 1.25
Prominent activation of brainstem and pallidal afferents of the ventral tegmental area by cocaine. Neuropsychopharmacology (2007) 1.23
Presynaptic opioid and nicotinic receptor modulation of dopamine overflow in the nucleus accumbens. J Neurosci (2008) 1.22
Ethanol-induced conditioned place preference is expressed through a ventral tegmental area dependent mechanism. Behav Neurosci (2005) 1.22
c-Fos expression associated with reinstatement of cocaine-seeking behavior by response-contingent conditioned cues. Synapse (2009) 1.18
Orexin-1 receptor signalling within the ventral tegmental area, but not the paraventricular thalamus, is critical to regulating cue-induced reinstatement of cocaine-seeking. Int J Neuropsychopharmacol (2011) 1.17
Inactivation of the bed nucleus of the stria terminalis in an animal model of relapse: effects on conditioned cue-induced reinstatement and its enhancement by yohimbine. Psychopharmacology (Berl) (2010) 1.16
Adrenergic and noradrenergic innervation of the midbrain ventral tegmental area and retrorubral field: prominent inputs from medullary homeostatic centers. J Neurosci (2009) 1.15
Interactions between VTA orexin and glutamate in cue-induced reinstatement of cocaine seeking in rats. Psychopharmacology (Berl) (2012) 1.15
Stimulation of the prefrontal cortex in the rat induces patterns of activity in midbrain dopaminergic neurons which resemble natural burst events. Synapse (1996) 1.14
Neurobiological substrates of cue-elicited craving and anhedonia in recently abstinent opioid-dependent males. Drug Alcohol Depend (2008) 1.14
Connections of the median and dorsal raphe nuclei in the rat: an autoradiographic and degeneration study. J Comp Neurol (1974) 1.14
A septal-hypothalamic pathway drives orexin neurons, which is necessary for conditioned cocaine preference. J Neurosci (2012) 1.13
Enkephalin co-expression with classic neurotransmitters in the amygdaloid complex of the rat. J Comp Neurol (2008) 1.12
Nucleus accumbens dopamine/glutamate interaction switches modes to generate desire versus dread: D(1) alone for appetitive eating but D(1) and D(2) together for fear. J Neurosci (2011) 1.10
Activation of afferents to the ventral tegmental area in response to acute amphetamine: a double-labelling study. Eur J Neurosci (2007) 1.08
Orexin/hypocretin modulates response of ventral tegmental dopamine neurons to prefrontal activation: diurnal influences. J Neurosci (2010) 1.07
A ventral tegmental CRF-glutamate-dopamine interaction in addiction. Brain Res (2009) 1.07
Ventral tegmental afferents in stress-induced reinstatement: the role of cAMP response element-binding protein. J Neurosci (2010) 1.06
Upregulation of Arc mRNA expression in the prefrontal cortex following cue-induced reinstatement of extinguished cocaine-seeking behavior. Synapse (2008) 1.05
Cocaine reward and hyperactivity in the rat: sites of mu opioid receptor modulation. Neuroscience (2008) 1.04
gamma-Aminobutyric acid cells with cocaine-induced DeltaFosB in the ventral tegmental area innervate mesolimbic neurons. Biol Psychiatry (2010) 1.04
Differential projections from the lateral habenula to the rostromedial tegmental nucleus and ventral tegmental area in the rat. J Comp Neurol (2012) 1.04
Efferents from medial basal forebrain and hypothalamus in the rat. I. An autoradiographic study of the medial preoptic area. J Comp Neurol (1976) 1.03
Glutamate and GABA in lateral hypothalamic mechanisms controlling food intake. Physiol Behav (2011) 1.01