Published in Clin Cardiol on January 01, 1985
Initial sequencing and analysis of the human genome. Nature (2001) 212.86
A physical map of the human genome. Nature (2001) 12.39
The DNA sequence of human chromosome 21. Nature (2000) 10.66
The genome of the social amoeba Dictyostelium discoideum. Nature (2005) 9.18
A metabolism experiment with special reference to the origin of uric acid. J Physiol (1909) 8.93
Activating Smoothened mutations in sporadic basal-cell carcinoma. Nature (1998) 7.43
Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system. Neuron (2000) 6.92
Molecular basis of symbiosis between Rhizobium and legumes. Nature (1997) 6.66
Bisulfite genomic sequencing: systematic investigation of critical experimental parameters. Nucleic Acids Res (2001) 5.89
The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog. Nature (1996) 5.69
Pseudoautosomal deletions encompassing a novel homeobox gene cause growth failure in idiopathic short stature and Turner syndrome. Nat Genet (1997) 4.95
Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome. Cell (1998) 4.72
DNA sequences required for regulated expression of beta-globin genes in murine erythroleukemia cells. Cell (1984) 4.42
Renal and neuronal abnormalities in mice lacking GDNF. Nature (1996) 4.06
Positional cloning of the gene for X-linked retinitis pigmentosa 2. Nat Genet (1998) 4.01
GDNF: a potent survival factor for motoneurons present in peripheral nerve and muscle. Science (1994) 3.63
FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate. Cell (1998) 3.33
Sequence requirements for the transcription of the rabbit beta-globin gene in vivo: the -80 region. Nucleic Acids Res (1982) 3.11
Topical ketorolac tromethamine 0.5% ophthalmic solution in ocular inflammation after cataract surgery. Ophthalmology (2001) 3.01
Characterization of a multicomponent receptor for GDNF. Nature (1996) 2.92
Drinks like a fish: zebra fish (Danio rerio) as a behavior genetic model to study alcohol effects. Pharmacol Biochem Behav (2000) 2.83
Use of barium sulphate as a continuous marker for faeces. J Clin Pathol (1967) 2.79
THE FILTRATION RATE, EFFECTIVE RENAL BLOOD FLOW, TUBULAR EXCRETORY MASS AND PHENOL RED CLEARANCE IN SPECIFIC TOXEMIA OF PREGANANCY. J Clin Invest (1942) 2.65
X-linked spastic paraplegia (SPG1), MASA syndrome and X-linked hydrocephalus result from mutations in the L1 gene. Nat Genet (1994) 2.53
An L-type calcium-channel gene mutated in incomplete X-linked congenital stationary night blindness. Nat Genet (1998) 2.48
N-myc downstream-regulated gene 1 is mutated in hereditary motor and sensory neuropathy-Lom. Am J Hum Genet (2000) 2.47
Expression in rat fibroblasts of a human transforming growth factor-alpha cDNA results in transformation. Cell (1986) 2.41
Noninvasive tests in the initial evaluation of heart murmurs in children. N Engl J Med (1983) 2.39
GFRalpha1 is an essential receptor component for GDNF in the developing nervous system and kidney. Neuron (1998) 2.34
Continuous subcutaenous administration of deferoxamine in patients with iron overload. N Engl J Med (1977) 2.31
The long QT syndrome in children. An international study of 287 patients. Circulation (1993) 2.31
Simian immunodeficiency virus disease course is predicted by the extent of virus replication during primary infection. J Virol (1999) 2.29
Interrupted aortic arch: surgical treatment. Am J Cardiol (1971) 2.24
Mutations in a new gene, encoding a zinc-finger protein, cause tricho-rhino-phalangeal syndrome type I. Nat Genet (2000) 2.23
Molecular characterization of a common fragile site (FRA7H) on human chromosome 7 by the cloning of a simian virus 40 integration site. Proc Natl Acad Sci U S A (1998) 2.16
Discovery of new human beta-defensins using a genomics-based approach. Gene (2001) 2.08
Induction of midbrain dopaminergic neurons by Sonic hedgehog. Neuron (1995) 2.08
A genome-wide survey of RAS transformation targets. Nat Genet (2000) 2.06
Neurotrophin-5: a novel neurotrophic factor that activates trk and trkB. Neuron (1991) 2.03
Large-scale methylation analysis of human genomic DNA reveals tissue-specific differences between the methylation profiles of genes and pseudogenes. Hum Mol Genet (2000) 2.02
Inactivating mutations and overexpression of BCL10, a caspase recruitment domain-containing gene, in MALT lymphoma with t(1;14)(p22;q32). Nat Genet (1999) 1.96
Sepsis and congenital asplenia. J Pediatr (1977) 1.93
Developmental regulation of expression and activity of multiple forms of the Drosophila RAC protein kinase. J Biol Chem (1995) 1.91
Sequence, structure, and evolution of a complete human olfactory receptor gene cluster. Genomics (2000) 1.88
A regulator of transcriptional elongation controls vertebrate neuronal development. Nature (2000) 1.87
Interrupted aortic arch in infancy. J Pediatr (1976) 1.83
Cardiotrophin-1. Biological activities and binding to the leukemia inhibitory factor receptor/gp130 signaling complex. J Biol Chem (1995) 1.83
Sonic hedgehog signaling by the patched-smoothened receptor complex. Curr Biol (1999) 1.79
Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain. Nature (1995) 1.79
Sudden cardiac death and the use of implantable cardioverter-defibrillators in pediatric patients. The Pediatric Electrophysiology Society. Circulation (1993) 1.78
Activation of expression of hedgehog target genes in basal cell carcinomas. J Invest Dermatol (2001) 1.77
Lorist6, a cosmid vector with BamHI, NotI, ScaI and HindIII cloning sites and altered neomycin phosphotransferase gene expression. Gene (1987) 1.75
MethTools--a toolbox to visualize and analyze DNA methylation data. Nucleic Acids Res (2000) 1.74
Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli. J Cell Sci (1999) 1.74
Extracardiac abnormalities in infants with congenital heart disease. Pediatrics (1975) 1.73
Widespread expression of BDNF but not NT3 by target areas of basal forebrain cholinergic neurons. Science (1990) 1.71
Ketorolac tromethamine 0.5% ophthalmic solution in the treatment of moderate to severe ocular inflammation after cataract surgery: a randomized, vehicle-controlled clinical trial. Am J Ophthalmol (1999) 1.70
Characterization of ATM gene mutations in 66 ataxia telangiectasia families. Hum Mol Genet (1999) 1.66
Development of noradrenergic neurons in the zebrafish hindbrain requires BMP, FGF8, and the homeodomain protein soulless/Phox2a. Neuron (1999) 1.65
Control of cell pattern in the neural tube by the zinc finger transcription factor and oncogene Gli-1. Neuron (1997) 1.65
Behavioral changes in developing mice after prenatal exposure to paroxetine (Paxil) Am J Obstet Gynecol (1999) 1.63
The rat trkC locus encodes multiple neurogenic receptors that exhibit differential response to neurotrophin-3 in PC12 cells. Neuron (1993) 1.61
A forty-year review of bacterial endocarditis in infancy and childhood. Circulation (1975) 1.60
Variations in DNA methylation during mouse cell differentiation in vivo and in vitro. Proc Natl Acad Sci U S A (1984) 1.59
Use of cuprous thiocyanate as a short-term continuous marker for faeces. Gut (1969) 1.59
Peritoneal migration of an abdominally implanted epicardial pacemaker: a cause of intestinal obstruction. Pacing Clin Electrophysiol (1995) 1.58
Selection for genes encoding secreted proteins and receptors. Proc Natl Acad Sci U S A (1996) 1.58
Vaccine protection of rhesus macaques against simian immunodeficiency virus infection. AIDS Res Hum Retroviruses (1990) 1.56
Comparison of the ocular hypotensive lipid AGN 192024 with timolol: dosing, efficacy, and safety evaluation of a novel compound for glaucoma management. Arch Ophthalmol (2001) 1.56
Mechanism of Theiler's virus-induced demyelination in nude mice. Lab Invest (1986) 1.53
Promotion of central cholinergic and dopaminergic neuron differentiation by brain-derived neurotrophic factor but not neurotrophin 3. Proc Natl Acad Sci U S A (1991) 1.52
Percutaneous balloon valvuloplasty for treatment of congenital pulmonary valvular stenosis in children. J Am Coll Cardiol (1984) 1.52
Architecture and anatomy of the genomic locus encoding the human leukemia-associated transcription factor RUNX1/AML1. Gene (2001) 1.51
THE FILTRATION RATE, EFFECTIVE RENAL BLOOD FLOW, TUBULAR EXCRETORY MASS AND PHENOL RED CLEARANCE IN NORMAL PREGNANCY. J Clin Invest (1942) 1.50
Optimum treatment of discrete subaortic stenosis. Ann Thorac Surg (1992) 1.48
Acute hemodynamic effects of captopril in children with a congestive or restrictive cardiomyopathy. Circulation (1991) 1.47
Solid-phase methods for sequencing of nucleic acids I. Simultaneous sequencing of different oligodeoxyribonucleotides using a new, mechanically stable anion-exchange paper. Nucleic Acids Res (1985) 1.44
Genome sequence of bovine herpesvirus 4, a bovine Rhadinovirus, and identification of an origin of DNA replication. J Virol (2001) 1.44
Specification of dopaminergic and serotonergic neurons in the vertebrate CNS. Curr Opin Neurobiol (1999) 1.43
Tricuspid atresia: clinical course in 101 patients. Am J Cardiol (1975) 1.42
Projections of population-based twinning rates through the year 2100. J Reprod Med (1999) 1.42
Increased MHC H-2K gene transcription in cultured mouse embryo cells after adenovirus infection. Nature (1985) 1.41
Gli regulation by the opposing activities of fused and suppressor of fused. Nat Cell Biol (2000) 1.41
Deletions of fetal and adult muscle cDNA in Duchenne and Becker muscular dystrophy patients. EMBO J (1987) 1.40
Interaction of EcoRII restriction and modification enzymes with synthetic DNA fragments. VI. The binding and cleavage of substrates containing nucleotide analogs. Nucleic Acids Res (1985) 1.40
Isolation of Plasmodium berghei (malaria) parasites by ammonium chloride lysis of infected erythrocytes. Nat New Biol (1971) 1.38
Characterization of two patched receptors for the vertebrate hedgehog protein family. Proc Natl Acad Sci U S A (1998) 1.38
Transient atrioventricular block resulting from left ventricular angiography in infants with ventricular septal defect. Am J Cardiol (1989) 1.37
Exhaustive mining of EST libraries for genes differentially expressed in normal and tumour tissues. Nucleic Acids Res (1999) 1.37
Usefulness of the bidirectional Glenn procedure as staged reconstruction for the functional single ventricle. Am J Cardiol (1993) 1.36
Mutations in the zebrafish unmask shared regulatory pathways controlling the development of catecholaminergic neurons. Dev Biol (1999) 1.36
High-resolution transcriptional analysis of the symbiotic plasmid of Rhizobium sp. NGR234. Mol Microbiol (1999) 1.35
Pulmonary artery sling. J Thorac Cardiovasc Surg (1975) 1.35
Survival of athymic (nu/nu) mice after Theiler's murine encephalomyelitis virus infection by passive administration of neutralizing monoclonal antibody. J Virol (1989) 1.35
Shone's anomaly: operative results and late outcome. Ann Thorac Surg (1990) 1.35
GDNF is an age-specific survival factor for sensory and autonomic neurons. Neuron (1995) 1.34