Published in Mutat Res on July 01, 1985
Biological monitoring and surveillance results of Gulf War I veterans exposed to depleted uranium. Int Arch Occup Environ Health (2005) 0.87
Levels of seven urinary phthalate metabolites in a human reference population. Environ Health Perspect (2000) 5.63
Genomic instability in Gadd45a-deficient mice. Nat Genet (1999) 3.01
Genetic risk and carcinogen exposure: a common inherited defect of the carcinogen-metabolism gene glutathione S-transferase M1 (GSTM1) that increases susceptibility to bladder cancer. J Natl Cancer Inst (1993) 2.76
The 1.7 A crystal structure of human cell cycle checkpoint kinase Chk1: implications for Chk1 regulation. Cell (2000) 2.11
Why not use it all? Environ Health Perspect (1999) 2.04
Risk from low-dose exposures. Science (1994) 1.99
Steroid and non-steroid UDP glucuronyltransferase: glucuronidation of synthetic estrogens as steroids. J Steroid Biochem (1977) 1.62
Genotype/phenotype discordance for human arylamine N-acetyltransferase (NAT2) reveals a new slow-acetylator allele common in African-Americans. Carcinogenesis (1993) 1.62
Characterization of the dose-response of CYP1B1, CYP1A1, and CYP1A2 in the liver of female Sprague-Dawley rats following chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol Appl Pharmacol (1999) 1.43
Curvature of mouse satellite DNA and condensation of heterochromatin. Cell (1987) 1.41
The aetiology of acute otitis media in children. Occurrence of bacteria, L forms of bacteria and mycoplasma in the middle ear exudate. Relationship between bacterial findings in the middle ear exudate, nasopharynx and throat. Scand J Infect Dis (1971) 1.37
Association between CYP1A1 genotype, mRNA expression and enzymatic activity in humans. Pharmacogenetics (1994) 1.31
TCDD-induced changes in rat liver microsomal enzymes. Environ Health Perspect (1973) 1.24
Multiple DNA adducts in lymphocytes of smokers and nonsmokers determined by 32P-postlabeling analysis. Carcinogenesis (1990) 1.22
Ethnic variation in the CYP2E1 gene: polymorphism analysis of 695 African-Americans, European-Americans and Taiwanese. Pharmacogenetics (1994) 1.19
A model of acute methyl mercury intoxication in rats. Arch Pathol (1972) 1.15
The effect of dose, dose rate, route of administration, and species on tissue and blood levels of benzene metabolites. Environ Health Perspect (1989) 1.15
Epidemiology of acute otitis media in children. Acta Otolaryngol Suppl (1982) 1.14
Microbiology in serous otitis media. Ann Otol Rhinol Laryngol (1976) 1.14
Human monoclonal antibodies to Pf 155, a major antigen of malaria parasite Plasmodium falciparum. Science (1986) 1.11
The concentration of penicillin V in serum and middle ear exudate in acute otitis media in children. Scand J Infect Dis (1969) 1.11
Medicinal herbs in the United States: research needs. Environ Health Perspect (1999) 1.11
Serum levels of TCDD and dioxin-like chemicals in Rhesus monkeys chronically exposed to dioxin: correlation of increased serum PCB levels with endometriosis. Toxicol Sci (2001) 1.10
Dioxin-responsive genes: examination of dose-response relationships using quantitative reverse transcriptase-polymerase chain reaction. Cancer Res (1994) 1.08
Tumor necrosis factor involvement in 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated endotoxin hypersensitivity in C57BL/6J mice congenic at the Ah locus. Toxicol Appl Pharmacol (1991) 1.06
Monoclonal anti-parasite and anti-RBC antibodies produced by stable EBV-transformed B cell lines from malaria patients. J Immunol (1983) 1.05
CYP1A1 mRNA levels as a human exposure biomarker: use of quantitative polymerase chain reaction to measure CYP1A1 expression in human peripheral blood lymphocytes. Carcinogenesis (1993) 1.05
Mercury uptake by renal lysosomes of rats ingesting methyl mercury hydroxide. Ultrastructural observations and energy dispersive x-ray analysis. Arch Pathol (1974) 1.05
Animal models of human response to dioxins. Environ Health Perspect (1998) 1.05
Decreased human birth weights after in utero exposure to PCBs and PCDFs are associated with decreased placental EGF-stimulated receptor autophosphorylation capacity. Mol Pharmacol (1987) 1.02
Inhibition of glycogenolysis in primary rat hepatocytes by 1, 4-dideoxy-1,4-imino-D-arabinitol. Biochem J (1999) 1.02
Levels of methyleugenol in a subset of adults in the general U.S. population as determined by high resolution mass spectrometry. Environ Health Perspect (2000) 1.02
Dose-response relationships for chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in a rat tumor promotion model: quantification and immunolocalization of CYP1A1 and CYP1A2 in the liver. Cancer Res (1992) 1.02
Nature of the enhancement of hepatic uridine diphosphate glucuronyltransferase activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats. Biochem Pharmacol (1975) 1.01
Isolation and characterization of a novel gene induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat liver. Carcinogenesis (1996) 1.01
Kinetic and functional characterization of 1,4-dideoxy-1, 4-imino-d-arabinitol: a potent inhibitor of glycogen phosphorylase with anti-hyperglyceamic effect in ob/ob mice. Arch Biochem Biophys (2000) 1.01
High-affinity lead binding proteins in rat kidney cytosol mediate cell-free nuclear translocation of lead. J Pharmacol Exp Ther (1985) 0.99
Microsomal rat liver UDP glucuronyltransferase: effects of piperonyl butoxide and other factors on enzyme activity. Arch Biochem Biophys (1971) 0.99
Glutathione S-transferase mu in human lymphocyte and liver: role in modulating formation of carcinogen-derived DNA adducts. Carcinogenesis (1991) 0.99
Epidemiology of acute otitis media in children. Scand J Infect Dis Suppl (1983) 0.99
Glucuronidation and deglucuronidation reactions in hepatic and extrahepatic tissues during perinatal development. Drug Metab Dispos (1977) 0.97
Contribution of genetic and nutritional factors to DNA damage in heavy smokers. Carcinogenesis (1997) 0.97
Toxicological assessment of hexachlorobiphenyl isomers and 2,3,7,8,-tetrachlorodibenzofuran in chicks. II. Effects on drug metabolism and porphyrin accumulation. Toxicol Appl Pharmacol (1976) 0.96
Inhibition of acute TCDD toxicity by treatment with anti-tumor necrosis factor antibody or dexamethasone. Toxicol Appl Pharmacol (1992) 0.96
The effects of chronic oral methyl mercury exposure on the lysosome system of rat kidney. Morphometric and biochemical studies. Lab Invest (1975) 0.95
A mechanistic model of effects of dioxin on gene expression in the rat liver. Toxicol Appl Pharmacol (1993) 0.95
Effects of prenatal exposure to cocaine and associated risk factors on language development. J Speech Hear Res (1995) 0.95
The potentiation of barbiturate-induced narcosis by procarbazine. J Pharmacol Exp Ther (1976) 0.95
Acute otitis media in Sweden. Role of Branhamella catarrhalis and the rationale for choice of antimicrobial therapy. Drugs (1986) 0.94
Postnatal stimulation of hepatic microsomal enzymes following administration of TCDD to pregnant rats. Chem Biol Interact (1975) 0.94
Genetic monitoring of human polymorphic cancer susceptibility genes by polymerase chain reaction: application to glutathione transferase mu. Environ Health Perspect (1992) 0.93
Workshop overview. National Toxicology Program Studies: principles of dose selection and applications to mechanistic based risk assessment. Fundam Appl Toxicol (1996) 0.93
Ovarian tumors in rats induced by chronic 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment. Cancer Res (2000) 0.93
The effects of polychlorinated biphenyls given prenatally on the neurobehavioral development of mice. Environ Res (1979) 0.93
Induction and suppression of hepatic and extrahepatic microsomal foreign-compound-metabolizing enzyme systems by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Chem Biol Interact (1975) 0.93
Photocarcinogenesis in hairless mice induced by ultraviolet A tanning devices with or without subsequent solar-simulated ultraviolet irradiation. Photodermatol Photoimmunol Photomed (1991) 0.92
Altered sexual differentiation of hepatic uridine diphosphate glucuronyltransferase by neonatal hormone treatment in rats. Biochem J (1979) 0.92
Penicillin treatment of acute otitis media in children. A study of the duration of treatment. Acta Otolaryngol (1983) 0.91
Rat CYP1B1: an adrenal cytochrome P450 that exhibits sex-dependent expression in livers and kidneys of TCDD-treated animals. Carcinogenesis (1995) 0.91
Frequency of typable and non-typable Haemophilus influenzae strains in children with acute otitis media and results of penicillin V treatment. Scand J Infect Dis (1971) 0.90
[The motion center in the lumbar spine during flexion and extension]. Z Anat Entwicklungsgesch (1972) 0.90
Sex differences in estrogen binding by cytosolic and nuclear components of rat liver. J Steroid Biochem (1980) 0.89
A mechanistic model of effects of dioxin on thyroid hormones in the rat. Toxicol Appl Pharmacol (1996) 0.89
Induction of hepatic 8-oxo-deoxyguanosine adducts by 2,3,7,8-tetrachlorodibenzo-p-dioxin in Sprague-Dawley rats is female-specific and estrogen-dependent. Chem Res Toxicol (2001) 0.89
Alterations in rat liver microsomal and lysosomal -glucuronidase by compounds which induce hepatic drug metabolizing enzymes. Biochim Biophys Acta (1972) 0.89
Altered ontogeny of hepatic steroid-metabolizing enzymes by pure polychlorinated biphenyl congeners. Biochem Pharmacol (1979) 0.89
Regulation of glucagon receptor mRNA in cultured primary rat hepatocytes by glucose and cAMP. J Biol Chem (1995) 0.88
Concentration of penicillin V in serum and middle ear exudate during treatment of acute otitis media. Ann Otol Rhinol Laryngol Suppl (1981) 0.87
Mechanism of action of toxic halogenated aromatics. Environ Health Perspect (1985) 0.87
Patients with dementia in group living: experiences 4 years after admission. Int Psychogeriatr (1995) 0.87
The concentration of penicillin-V in middle ear exudate. Int J Pediatr Otorhinolaryngol (1979) 0.86
Induction of lung lesions in female rats following chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol Pathol (2000) 0.85
A toxic equivalency factor scale for polychlorinated dibenzofurans. Fundam Appl Toxicol (1994) 0.85
Metabolic activation/deactivation reactions during perinatal development. Environ Health Perspect (1979) 0.85
Dose-dependent localization of TCDD in isolated centrilobular and periportal hepatocytes. Toxicol Sci (1999) 0.85
Structural requirements for the accumulation of chlorinated biphenyl metabolites in the fetal rat intestine. Drug Metab Dispos (1979) 0.85
Biomonitoring of genotoxic exposure among stainless steel welders. Mutat Res (1992) 0.85
DNA, RNA, and protein synthesis in brain, liver, and kidneys of asymptomatic methylmercury treated rats. Exp Mol Pathol (1973) 0.85
The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the hepatic estrogen and glucocorticoid receptors in congenic strains of Ah responsive and Ah nonresponsive C57BL/6J mice. Toxicol Appl Pharmacol (1991) 0.84
Induction and localization of cytochrome P450 1B1 (CYP1B1) protein in the livers of TCDD-treated rats: detection using polyclonal antibodies raised to histidine-tagged fusion proteins produced and purified from bacteria. Carcinogenesis (1998) 0.84
Influence of the Ah locus on the effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the hepatic epidermal growth factor receptor. Mol Pharmacol (1991) 0.84
Involvement of cytochrome P-450c in alpha-naphthoflavone metabolism by rat liver microsomes. Mol Pharmacol (1990) 0.84
Epidemiology of acute otitis media in children in an urban population. Auris Nasus Larynx (1985) 0.83
The right to know is for everyone. Environ Health Perspect (2000) 0.83
Overproduction of MDM2 in vivo disrupts S phase independent of E2F1. Cell Growth Differ (1999) 0.83
Accumulation of polychlorinated dibenzo-p-dioxins and dibenzofurans in liver of control laboratory rats. Fundam Appl Toxicol (1994) 0.83
Translocation of 4S and 5S forms of estrogen-receptors into rat liver nuclei in vitro. Biochem Biophys Res Commun (1978) 0.83
Increased tumor necrosis factor-alpha production by peripheral blood leukocytes from TCDD-exposed rhesus monkeys. Toxicol Sci (2001) 0.83
Synthesis and deconvolution of the first combinatorial library of glycosidase inhibitors. Bioorg Med Chem (1999) 0.82
Risk assessment: good science for good decisions. Environ Health Perspect (1993) 0.82
Iminosugars: potential inhibitors of liver glycogen phosphorylase. Bioorg Med Chem (2001) 0.82
Relationships among benzo(a)pyrene metabolism, benzo(a)pyrene-diol-epoxide:DNA adduct formation, and sister chromatid exchanges in human lymphocytes from smokers and nonsmokers. Cancer Res (1989) 0.82
Comparison of DNA adduct levels in human placenta from polychlorinated biphenyl exposed women and smokers in which CYP 1A1 levels are similarly elevated. Teratog Carcinog Mutagen (1994) 0.82
Ultrastructural changes in rat liver cells following a single oral dose of TCDD. Environ Health Perspect (1973) 0.82
Effects of methylmercury on microsomal mixed-function oxidase components of rodents. Mol Pharmacol (1973) 0.82
Increased oxidative DNA damage in livers of 2,3,7,8-tetrachlorodibenzo-p-dioxin treated intact but not ovariectomized rats. Cancer Lett (1996) 0.81
Alterations in thyroid function in female Sprague-Dawley rats following chronic treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol Appl Pharmacol (1995) 0.81
Persistence of TCDD-induced hepatic cell proliferation and growth of enzyme altered foci after chronic exposure followed by cessation of treatment in DEN initiated female rats. Carcinogenesis (1995) 0.81
Nondetectable concentrations of human placental Ah receptors are associated with potent induction of microsomal benzo[a]pyrene hydroxylase in individuals exposed to polychlorinated biphenyls, quaterphenyls, and dibenzofurans. Toxicol Appl Pharmacol (1986) 0.81