Published in Circulation on October 01, 1985
Direct measurement of free radical generation following reperfusion of ischemic myocardium. Proc Natl Acad Sci U S A (1987) 4.87
Demonstration of free radical generation in "stunned" myocardium of intact dogs with the use of the spin trap alpha-phenyl N-tert-butyl nitrone. J Clin Invest (1988) 2.02
Direct evidence that oxygen-derived free radicals contribute to postischemic myocardial dysfunction in the intact dog. Proc Natl Acad Sci U S A (1989) 1.90
Oxygen-derived free radicals and myocardial reperfusion injury: an overview. Cardiovasc Drugs Ther (1991) 1.23
Oxygen radicals generated at reflow induce peroxidation of membrane lipids in reperfused hearts. J Clin Invest (1991) 1.20
Myocardial ischemia and reperfusion: direct evidence for free radical generation by electron spin resonance spectroscopy. Proc Natl Acad Sci U S A (1988) 1.00
Role of nitric oxide and peroxynitrite in the cytokine-induced sustained myocardial dysfunction in dogs in vivo. J Clin Invest (1998) 0.92
Reactive oxygen metabolites and the human myocardium. Br Heart J (1989) 0.92
Reperfusion-induced injury: a possible role for oxidant stress and its manipulation. Cardiovasc Drugs Ther (1991) 0.90
Relationships between structure and effects of ACE inhibitors: comparative effects in myocardial ischaemic/reperfusion injury. Br J Clin Pharmacol (1989) 0.89
Novel mechanisms mediating stunned myocardium. Heart Fail Rev (2003) 0.89
Reduction of oxidative stress does not affect recovery of myocardial function: warm continuous versus cold intermittent blood cardioplegia. Heart (1997) 0.86
Reperfusion Injury: Basic Concepts and Protection Strategies. J Thromb Thrombolysis (1997) 0.84
Glutathione alters calcium responsiveness of cardiac skinned fibers. Basic Res Cardiol (1990) 0.84
Ischemia, reperfusion, and the determinants of tissue injury. Cardiovasc Drugs Ther (1990) 0.83
Catecholamine cardiomyopathy: review and analysis of pathogenetic mechanisms. Yale J Biol Med (1991) 0.82
Cardioprotective actions of human superoxide dismutase in two reperfusion models of myocardial ischaemia in the rat. Br J Pharmacol (1988) 0.80
Effect of oxygen-derived free radical scavengers on infarct size following six hours of permanent coronary artery occlusion: salvage or delay of myocyte necrosis? Basic Res Cardiol (1987) 0.79
Failure of allopurinol and a spin trapping agent N-t-butyl-alpha-phenyl nitrone to modify significantly ischaemia and reperfusion-induced arrhythmias. Br J Pharmacol (1987) 0.76
Effect of vitamin E administration on blood pressure following reperfusion of patients with myocardial infarction. Exp Clin Cardiol (2007) 0.75
Cardiac protein changes in rats after soybean oil treatment: a proteomic study. Lipids Health Dis (2015) 0.75
Hydrogen peroxide generation by mitochondria isolated from regionally ischemic and nonischemic dog myocardium. Basic Res Cardiol (1990) 0.75
A new hydroxyl radical scavenger "EPC" on cadaver heart transplantation in a canine model. Surg Today (1997) 0.75
The Effects of Experimental Sleep Apnea on Cardiac and Respiratory Functions in 6 and 18 Month Old Dystrophic (mdx) Mice. PLoS One (2016) 0.75
A controlled trial of teaching critical appraisal of the clinical literature to medical students. JAMA (1987) 14.20
Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells. J Clin Invest (2001) 7.20
Thrombolysis in Myocardial Infarction (TIMI) Trial, Phase I: A comparison between intravenous tissue plasminogen activator and intravenous streptokinase. Clinical findings through hospital discharge. Circulation (1987) 5.73
Circadian variation in the frequency of onset of acute myocardial infarction. N Engl J Med (1985) 5.09
Identification of a (CUG)n triplet repeat RNA-binding protein and its expression in myotonic dystrophy. Nucleic Acids Res (1996) 4.75
Identification of a genetic locus for familial atrial fibrillation. N Engl J Med (1997) 4.66
Second dose of measles, mumps, and rubella vaccine: questionnaire survey of health professionals. BMJ (2001) 4.50
Determining optimal therapy--randomized trials in individual patients. N Engl J Med (1986) 4.49
Identification of a gene responsible for familial Wolff-Parkinson-White syndrome. N Engl J Med (2001) 4.46
Mutations in the gene for cardiac myosin-binding protein C and late-onset familial hypertrophic cardiomyopathy. N Engl J Med (1998) 4.29
Synthesis of the yeast cell wall and its regulation. Annu Rev Biochem (1982) 4.26
Do sick newborn infants benefit from participation in a randomized clinical trial? J Pediatr (1999) 3.98
Comparison of percutaneous and surgical tracheostomies. Chest (1996) 3.56
Myocardial ischemia and reperfusion: a murine model. Am J Physiol (1995) 3.38
WD-repeat proteins: structure characteristics, biological function, and their involvement in human diseases. Cell Mol Life Sci (2001) 3.38
A clinician's guide for conducting randomized trials in individual patients. CMAJ (1988) 3.35
Tissue Doppler imaging consistently detects myocardial abnormalities in patients with hypertrophic cardiomyopathy and provides a novel means for an early diagnosis before and independently of hypertrophy. Circulation (2001) 3.33
The late phase of ischemic preconditioning is abrogated by targeted disruption of the inducible NO synthase gene. Proc Natl Acad Sci U S A (1999) 3.32
Verifying quality and safety in health informatics services. BMJ (2001) 3.31
Opposing cardioprotective actions and parallel hypertrophic effects of delta PKC and epsilon PKC. Proc Natl Acad Sci U S A (2001) 3.28
Angiotensin II blockade reverses myocardial fibrosis in a transgenic mouse model of human hypertrophic cardiomyopathy. Circulation (2001) 3.21
Mutations in the lactose operon caused by bacteriophage Mu. J Mol Biol (1972) 3.17
Demonstration of an early and a late phase of ischemic preconditioning in mice. Am J Physiol (1998) 3.11
Quantitative effects of dietary fat on serum cholesterol in man. Am J Clin Nutr (1965) 3.00
The impact of blinding on the results of a randomized, placebo-controlled multiple sclerosis clinical trial. Neurology (1994) 2.95
Ipsilateral breast tumor recurrence postlumpectomy is predictive of subsequent mortality: results from a randomized trial. Investigators of the Ontario Clinical Oncology Group. Int J Radiat Oncol Biol Phys (1994) 2.86
Allergen-induced increase in bronchial responsiveness to histamine: relationship to the late asthmatic response and change in airway caliber. J Allergy Clin Immunol (1982) 2.84
The molecular genetic basis for hypertrophic cardiomyopathy. J Mol Cell Cardiol (2001) 2.83
A comparison between heparin and low-dose aspirin as adjunctive therapy with tissue plasminogen activator for acute myocardial infarction. Heparin-Aspirin Reperfusion Trial (HART) Investigators. N Engl J Med (1990) 2.73
A standard heparin nomogram for the management of heparin therapy. Arch Intern Med (1991) 2.69
It's time for a change to a troponin standard. Circulation (2000) 2.69
The impact of socioeconomic status on health functioning as assessed by the SF-36 questionnaire: the Whitehall II Study. Am J Public Health (1997) 2.65
Reliability of a Standardized Mini-Mental State Examination compared with the traditional Mini-Mental State Examination. Am J Psychiatry (1991) 2.61
Preconditioning of human myocardium with adenosine during coronary angioplasty. Circulation (1997) 2.60
Desmin mutation responsible for idiopathic dilated cardiomyopathy. Circulation (1999) 2.59
Impairment of endothelium-dependent arterial relaxation by lysolecithin in modified low-density lipoproteins. Nature (1990) 2.46
Angiotensin-converting enzyme polymorphism in hypertrophic cardiomyopathy and sudden cardiac death. Lancet (1993) 2.38
Echocardiography-guided ethanol septal reduction for hypertrophic obstructive cardiomyopathy. Circulation (1998) 2.37
APOE modifies the association between Aβ load and cognition in cognitively normal older adults. Neurology (2011) 2.35
Influence of coronary collateral vessels on myocardial infarct size in humans. Results of phase I thrombolysis in myocardial infarction (TIMI) trial. The TIMI Investigators. Circulation (1991) 2.33
Cyclooxygenase-2 mediates the cardioprotective effects of the late phase of ischemic preconditioning in conscious rabbits. Proc Natl Acad Sci U S A (2000) 2.28
Novel PRKAG2 mutation responsible for the genetic syndrome of ventricular preexcitation and conduction system disease with childhood onset and absence of cardiac hypertrophy. Circulation (2001) 2.25
Simvastatin induces regression of cardiac hypertrophy and fibrosis and improves cardiac function in a transgenic rabbit model of human hypertrophic cardiomyopathy. Circulation (2001) 2.23
Adenosine as an adjunct to thrombolytic therapy for acute myocardial infarction: results of a multicenter, randomized, placebo-controlled trial: the Acute Myocardial Infarction STudy of ADenosine (AMISTAD) trial. J Am Coll Cardiol (1999) 2.23
Novel proteins with binding specificity for DNA CTG repeats and RNA CUG repeats: implications for myotonic dystrophy. Hum Mol Genet (1996) 2.23
A transgenic rabbit model for human hypertrophic cardiomyopathy. J Clin Invest (1999) 2.19
The nitric oxide hypothesis of late preconditioning. Basic Res Cardiol (1998) 2.19
Electrocardiographic and clinical criteria for recognition of acute myocardial infarction based on analysis of 3,697 patients. Am J Cardiol (1983) 2.18
Allergic Rhinitis and its Impact on Asthma (ARIA): achievements in 10 years and future needs. J Allergy Clin Immunol (2012) 2.17
Development and implementation of guidelines for family practice: lessons from The Netherlands. J Fam Pract (1995) 2.11
Diagnostic marker cooperative study for the diagnosis of myocardial infarction. Circulation (1999) 2.09
Identification of patients most likely to benefit from implantable cardioverter-defibrillator therapy: the Canadian Implantable Defibrillator Study. Circulation (2000) 2.05
Short and long term prognosis of acute myocardial infarction since introduction of thrombolysis. BMJ (1993) 2.03
Comparison of immediate invasive, delayed invasive, and conservative strategies after tissue-type plasminogen activator. Results of the Thrombolysis in Myocardial Infarction (TIMI) Phase II-A trial. Circulation (1990) 2.01
Isolation and sequence analysis of a full-length cDNA for human M creatine kinase. Biochem Biophys Res Commun (1986) 1.96
Medical and cellular implications of stunning, hibernation, and preconditioning: an NHLBI workshop. Circulation (1998) 1.96
Delayed preconditioning-mimetic action of nitroglycerin in patients undergoing coronary angioplasty. Circulation (2001) 1.91
Direct evidence that oxygen-derived free radicals contribute to postischemic myocardial dysfunction in the intact dog. Proc Natl Acad Sci U S A (1989) 1.90
Nitric oxide synthase is the mediator of late preconditioning against myocardial infarction in conscious rabbits. Circulation (1998) 1.90
Integrated patient records: another move towards quality for patients? Qual Health Care (1993) 1.88
Does breastfeeding at six months predict cognitive development? Aust N Z J Public Health (1998) 1.87
Randomized clinical trial of breast irradiation following lumpectomy and axillary dissection for node-negative breast cancer: an update. Ontario Clinical Oncology Group. J Natl Cancer Inst (1996) 1.86
Depression and risk of sudden cardiac death after acute myocardial infarction: testing for the confounding effects of fatigue. Psychosom Med (2000) 1.80
Familial colloid cyst of the third ventricle: case report and review of associated conditions. Neurosurgery (1996) 1.79
An improved basis for enzymatic estimation of infarct size. Circulation (1975) 1.77
Nuclear factor-kappaB plays an essential role in the late phase of ischemic preconditioning in conscious rabbits. Circ Res (1999) 1.75
The influence of location and extent of myocardial infarction on long-term ventricular dysrhythmia and mortality. Circulation (1979) 1.75
Can pulsed Doppler technique measure changes in aortic blood flow in conscious rats? Am J Physiol (1990) 1.74
An essential role of the JAK-STAT pathway in ischemic preconditioning. Proc Natl Acad Sci U S A (2001) 1.73
ABC of child abuse. Child sexual abuse--II. BMJ (1989) 1.72
Tissue Doppler imaging consistently detects myocardial contraction and relaxation abnormalities, irrespective of cardiac hypertrophy, in a transgenic rabbit model of human hypertrophic cardiomyopathy. Circulation (2000) 1.72
Severity of coronary artery calcification by electron beam computed tomography predicts silent myocardial ischemia. Circulation (2000) 1.70
Magnetic resonance spectroscopy, β-amyloid load, and cognition in a population-based sample of cognitively normal older adults. Neurology (2011) 1.70
Disability, distress and unemployment in neurology outpatients with symptoms 'unexplained by organic disease'. J Neurol Neurosurg Psychiatry (2011) 1.69
Electrocardiographic diagnosis of myocardial infarction in the presence of complete left bundle branch block. Am Heart J (1988) 1.69
Post-myocardial infarction mortality in patients with ventricular premature depolarizations. Canadian Amiodarone Myocardial Infarction Arrhythmia Trial Pilot Study. Circulation (1991) 1.68
Spontaneous delayed recovery of perfusion and contraction after the first 5 weeks after anterior infarction. Evidence for the presence of hibernating myocardium in the infarcted area. Circulation (1994) 1.68
Postprandial plasma bile acid responses in normal weight and obese subjects. Ann Clin Biochem (2010) 1.67
Effects of nifedipine on myocardial perfusion and ischemic injury in dogs. Circ Res (1978) 1.67
The struggle to diagnose UTI in children under two in primary care. Fam Pract (1997) 1.65
Deleterious effects of methylprednisolone in patients with myocardial infarction. Circulation (1976) 1.65
Myocardial infarction and remodeling in mice: effect of reperfusion. Am J Physiol (1999) 1.62
Early diagnosis of acute myocardial infarction based on assay for subforms of creatine kinase-MB. Circulation (1990) 1.61
Depression and substance use in minority middle-school students. Am J Public Health (2001) 1.61
Reducing tobacco addiction through tobacco product regulation. Tob Control (2004) 1.59
Functional proteomic analysis of protein kinase C epsilon signaling complexes in the normal heart and during cardioprotection. Circ Res (2001) 1.59
Optimal delivery of aerosols from metered dose inhalers. Chest (1981) 1.59
Fibrinolytic variables in patients with recurrent venous thrombosis: a prospective cohort study. Thromb Haemost (2001) 1.58
Unexplained extra visits to general practitioners before the diagnosis of first urinary tract infection: a case-control study. Arch Dis Child (2002) 1.58
Integrated record keeping as an essential aspect of a primary care led health service. BMJ (1998) 1.55
Serial plasma catecholamine response early in the course of clinical acute myocardial infarction: relationship to infarct extent and mortality. Am Heart J (1981) 1.54
Ten down under: implementing ICD-10 in Australia. J AHIMA (2000) 1.54
Paradoxical endogenous synthesis of a coronary dilating substance from arachidonate. Prostaglandins (1976) 1.52
Autonomous expression of c-myc in BC3H1 cells partially inhibits but does not prevent myogenic differentiation. Mol Cell Biol (1987) 1.52
ABC of child abuse. Child sexual abuse--I. BMJ (1989) 1.52
Evidence for an essential role of reactive oxygen species in the genesis of late preconditioning against myocardial stunning in conscious pigs. J Clin Invest (1996) 1.52