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The function of multiple extracellular matrix receptors in mediating cell adhesion to extracellular matrix: preparation of monoclonal antibodies to the fibronectin receptor that specifically inhibit cell adhesion to fibronectin and react with platelet glycoproteins Ic-IIa. J Cell Biol (1988) 3.67

Uptake of plasma fibrinogen into the alpha granules of human megakaryocytes and platelets. J Clin Invest (1989) 1.30

Incorporation of intravenously injected albumin, immunoglobulin G, and fibrinogen in guinea pig megakaryocyte granules. J Clin Invest (1989) 1.06

Plasminogen interacts with human platelets through two distinct mechanisms. J Clin Invest (1986) 1.00

Lateral diffusion of lipid probes in the surface membrane of human platelets. An electron-electron double resonance (ELDOR) study. Biophys J (1986) 0.97

Platelet alpha-granule fibrinogen, albumin, and immunoglobulin G are not synthesized by rat and mouse megakaryocytes. J Clin Invest (1990) 0.89

Kistrin, an integrin antagonist, blocks endocytosis of fibrinogen into guinea pig megakaryocyte and platelet alpha-granules. J Clin Invest (1993) 0.89

Localization of human platelet autoantigens to the cysteine-rich region of glycoprotein IIIa. J Clin Invest (1991) 0.87

The cold-insoluble globulin of human plasma. I. Purification, primary characterization, and relationship to fibrinogen and other cold-insoluble fraction components. J Biol Chem (1970) 4.49

Receptors for cold-insoluble globulin (plasma fibronectin) on human monocytes. J Exp Med (1981) 3.93

Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion molecule. J Cell Biol (1991) 3.91

The function of multiple extracellular matrix receptors in mediating cell adhesion to extracellular matrix: preparation of monoclonal antibodies to the fibronectin receptor that specifically inhibit cell adhesion to fibronectin and react with platelet glycoproteins Ic-IIa. J Cell Biol (1988) 3.67

Interactions among heparin, cold-insoluble globulin, and fibrinogen in formation of the heparin-precipitable fraction of plasma. J Clin Invest (1977) 2.96

The structure and biologic activities of plasma fibronectin. Blood (1980) 2.94

Base excess and lactate as prognostic indicators for patients admitted to intensive care. Intensive Care Med (2001) 2.86

Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development. Development (1994) 2.71

The cold-insoluble globulin of human plasma: studies of its essential structural features. Biochim Biophys Acta (1975) 2.51

CD31 expressed on distinctive T cell subsets is a preferential amplifier of beta 1 integrin-mediated adhesion. J Exp Med (1992) 2.38

Analysis of platelet membrane glycoprotein polymorphisms in Glanzmann thrombasthenia showed the French gypsy mutation in the alphaIIb gene to be strongly linked to the HPA-1b polymorphism in beta3. J Thromb Haemost (2003) 2.20

Interaction of AP-2, a monoclonal antibody specific for the human platelet glycoprotein IIb-IIIa complex, with intact platelets. J Biol Chem (1983) 2.09

Molecular and functional aspects of PECAM-1/CD31. Immunol Today (1994) 2.04

Identification and mass analysis of human fibrinogen molecules and their domains by scanning transmission electron microscopy. J Mol Biol (1981) 2.01

The formation of Ca++-dependent complexes of platelet membrane glycoproteins IIb and IIIa in solution as determined by crossed immunoelectrophoresis. Blood (1981) 1.86

Aspirin resistance: position paper of the Working Group on Aspirin Resistance. J Thromb Haemost (2005) 1.83

Isolation and characterization of photosystem I and II membrane particles from the blue-green alga, Synechococcus cedrorum. Biochim Biophys Acta (1978) 1.80

On the association of glycoprotein Ib and actin-binding protein in human platelets. J Cell Biol (1985) 1.80

Characterization of a mouse model for thrombomodulin deficiency. Arterioscler Thromb Vasc Biol (2001) 1.76

Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery. J Clin Invest (1986) 1.71

A prospective study of the use of a dobutamine stress test to identify outcome in patients with sepsis, severe sepsis, or septic shock. Crit Care Med (1999) 1.70

Topography of ligand-induced binding sites, including a novel cation-sensitive epitope (AP5) at the amino terminus, of the human integrin beta 3 subunit. J Biol Chem (1995) 1.70

Analysis of the glycoprotein and protein composition of Bernard-Soulier platelets by single and two-dimensional sodium dodecyl sulfate-polyacrylamide gel electrophoresis. J Clin Invest (1981) 1.62

A new role for platelet-endothelial cell adhesion molecule-1 (CD31): inhibition of TCR-mediated signal transduction. J Immunol (1999) 1.61

Platelet/endothelial cell adhesion molecule-1 (CD31)-mediated cellular aggregation involves cell surface glycosaminoglycans. J Biol Chem (1993) 1.55

A heterophilic adhesion mechanism for platelet/endothelial cell adhesion molecule 1 (CD31). J Exp Med (1992) 1.55

Heterogeneity of the cold-insoluble globulin of human plasma (CIg), a circulating cell surface protein. Biochim Biophys Acta (1977) 1.54

Quantitation of membrane glycoprotein IIIa on intact human platelets using the monoclonal antibody, AP-3. Blood (1985) 1.54

Degradation of human fibrinogen by plasms alpha2-macroglobulin-enzyme complexes. J Clin Invest (1973) 1.54

The protein-tyrosine phosphatase SHP-2 binds platelet/endothelial cell adhesion molecule-1 (PECAM-1) and forms a distinct signaling complex during platelet aggregation. Evidence for a mechanistic link between PECAM-1- and integrin-mediated cellular signaling. J Biol Chem (1997) 1.53

A study of variables affecting the quality of platelets stored at "room temperature". Transfusion (1976) 1.52

Nucleotide polymorphisms in the alpha2 gene define multiple alleles that are associated with differences in platelet alpha2 beta1 density. Blood (1998) 1.51

Individually distinct Ig homology domains in PECAM-1 regulate homophilic binding and modulate receptor affinity. J Biol Chem (1996) 1.50

Protransglutaminase (factor XIII) mediated crosslinking of fibrinogen and fibrin. Thromb Haemost (2001) 1.48

Platelet endothelial cell adhesion molecule-1 serves as an inhibitory receptor that modulates platelet responses to collagen. Blood (2001) 1.42

Diagnosis of Bernard-Soulier syndrome and Glanzmann's thrombasthenia with a monoclonal assay on whole blood. J Clin Invest (1983) 1.40

Sevoflurane anaesthesia for major intra-abdominal surgery. Anaesthesia (1994) 1.40

Clinical significance of the growth of micro-organisms in propofol. Anaesthesia (1993) 1.39

Detection and quantitation of fibronectin in synovial fluid from patients with rheumatic disease. Arthritis Rheum (1981) 1.38

Treating hyperhidrosis. Complications of endoscopic sympathectomy. BMJ (1993) 1.38

Release of platelet fibronectin (cold-insoluble globulin) from alpha granules induced by thrombin or collagen; lack of requirement for plasma fibronectin in ADP-induced platelet aggregation. Blood (1979) 1.37

Human fibrinogen heterogeneities. I. Structural and related studies of plasma fibrinogens which are high solubility catabolic intermediates. J Biol Chem (1972) 1.37

Characterization of phosphotyrosine binding motifs in the cytoplasmic domain of platelet/endothelial cell adhesion molecule-1 (PECAM-1) that are required for the cellular association and activation of the protein-tyrosine phosphatase, SHP-2. J Biol Chem (1997) 1.36

Divalent cation regulation of the surface orientation of platelet membrane glycoprotein IIb. Correlation with fibrinogen binding function and definition of a novel variant of Glanzmann's thrombasthenia. J Clin Invest (1986) 1.35

Production of fibronectin by human epithelial cells in culture. Cancer Res (1979) 1.34

Rapid determination of platelet alloantigen genotypes by polymerase chain reaction using allele-specific primers. Transfusion (1994) 1.33

Enzymatic amplification of specific cDNA inserts from lambda gt11 libraries. Nucleic Acids Res (1988) 1.31

Effect of calcium on the stability of the platelet membrane glycoprotein IIb-IIIa complex. J Biol Chem (1985) 1.31

The preparation and properties of human fibrinogen of relatively high solubility. Biochemistry (1966) 1.31

Antibodies against the first Ig-like domain of human platelet endothelial cell adhesion molecule-1 (PECAM-1) that inhibit PECAM-1-dependent homophilic adhesion block in vivo neutrophil recruitment. J Immunol (2000) 1.29

Detection and characterization of monoclonal antibodies to platelet membrane proteins. J Cell Biol (1981) 1.29

Structure of the human gene encoding granule membrane protein-140, a member of the selectin family of adhesion receptors for leukocytes. J Biol Chem (1990) 1.28

Inhibition of antigen-receptor signaling by Platelet Endothelial Cell Adhesion Molecule-1 (CD31) requires functional ITIMs, SHP-2, and p56(lck). Blood (2001) 1.26

Truncation of the cytoplasmic domain of beta3 in a variant form of Glanzmann thrombasthenia abrogates signaling through the integrin alpha(IIb)beta3 complex. J Clin Invest (1997) 1.26

Independent modulation of von Willebrand factor and fibrinogen binding to the platelet membrane glycoprotein IIb/IIIa complex as demonstrated by monoclonal antibody. J Clin Invest (1985) 1.23

Delayed-type hypersensitivity skin reactions in congenital afibrinogenemia lack fibrin deposition and induration. J Clin Invest (1979) 1.22

Isolation and immunologic characterization of the human platelet alloantigen, P1A1. Mol Immunol (1979) 1.21

Interaction of integrins alpha v beta 3 and glycoprotein IIb-IIIa with fibrinogen. Differential peptide recognition accounts for distinct binding sites. J Biol Chem (1990) 1.21

Control of a cell surface major glycoprotein by epidermal growth factor. Science (1977) 1.21

Human fibroblasts bind directly to fibrinogen at RGD sites through integrin alpha(v)beta3. Exp Cell Res (1997) 1.19

Human fibrinogen of relatively high solubility. Comparative biophysical, biochemical, and biological studies with fibrinogen of lower solubility. Biochemistry (1967) 1.17

Plasma factor XIII binds specifically to fibrinogen molecules containing gamma chains. Biochemistry (1996) 1.16

An improved method for purification of the cold-insoluble globulin of human plasma (CLg). Anal Biochem (1977) 1.16

Studies on the ultrastructure of fibrin lacking fibrinopeptide B (beta-fibrin). Blood (1987) 1.16

The molecular immunology of human platelet proteins. Blood (1992) 1.15

Cell surface fibrinogen-fibrin receptors on cultured human fibroblasts. Association with fibronectin (cold insoluble globulin, LETS protein) and loss in SV40 transformed cells. Lab Invest (1979) 1.15

Detection of drug-dependent, platelet-reactive antibodies by antigen-capture ELISA and flow cytometry. Transfusion (1990) 1.14

Absence of the platelet receptor for drug-dependent antibodies in the Bernard-Soulier syndrome. J Clin Invest (1978) 1.14

Glycoprotein Ic-IIa functions as an activation-independent fibronectin receptor on human platelets. J Cell Biol (1988) 1.13

A point mutation in the cysteine-rich domain of glycoprotein (GP) IIIa results in the expression of a GPIIb-IIIa (alphaIIbbeta3) integrin receptor locked in a high-affinity state and a Glanzmann thrombasthenia-like phenotype. Blood (2001) 1.13

Identification and characterization of the thrombin binding sites on fibrin. J Biol Chem (1996) 1.13

A molecular model of RGD ligands. Antibody D gene segments that direct specificity for the integrin alpha IIb beta 3. J Biol Chem (1992) 1.11

Identification of covalently linked trimeric and tetrameric D domains in crosslinked fibrin. Proc Natl Acad Sci U S A (1989) 1.10

Specific protein and glycoprotein deficiencies in platelets isolated from two patients with the gray platelet syndrome. Blood (1982) 1.10

Synthesis by cultured human umbilical vein endothelial cells of two proteins structurally and immunologically related to platelet membrane glycoproteins IIb and IIIa. J Cell Biol (1986) 1.10

Organization of the gene for human platelet/endothelial cell adhesion molecule-1 shows alternatively spliced isoforms and a functionally complex cytoplasmic domain. Blood (1994) 1.10

Cryoprecipitation of fibrin-fibrinogen complexes induced by the cold-insoluble globulin of plasma. Blood (1978) 1.10

Cleavage of human von Willebrand factor by platelet calcium-activated protease. Blood (1985) 1.09

Localization of internal pools of membrane glycoproteins involved in platelet adhesive responses. Am J Pathol (1986) 1.09

Contributions of the extracellular and cytoplasmic domains of platelet-endothelial cell adhesion molecule-1 (PECAM-1/CD31) in regulating cell-cell localization. J Cell Sci (2000) 1.09

Platelet/endothelial cell adhesion molecule-1 serves as a costimulatory agonist receptor that modulates integrin-dependent adhesion and aggregation of human platelets. Blood (1998) 1.09

Human plasma fibrinogen heterogeneity: evidence for an extended carboxyl-terminal sequence in a normal gamma chain variant (gamma'). Proc Natl Acad Sci U S A (1980) 1.08

Platelet endothelial cell adhesion molecule (CD31). Curr Top Microbiol Immunol (1993) 1.07

Characterization of the human platelet/endothelial cell adhesion molecule-1 promoter: identification of a GATA-2 binding element required for optimal transcriptional activity. Blood (1997) 1.07

Thrombospondin-1, a natural inhibitor of angiogenesis, regulates platelet-endothelial cell adhesion molecule-1 expression and endothelial cell morphogenesis. Mol Biol Cell (1997) 1.06

Further characterization of the thrombasthenia-related idiotype OG. Antiidiotype defines a novel epitope(s) shared by fibrinogen B beta chain, vitronectin, and von Willebrand factor and required for binding to beta 3. J Exp Med (1994) 1.06

Chronic intravascular coagulation syndrome. N Engl J Med (1968) 1.06

Deletion of the platelet-specific alloantigen PlA1 from platelets in Glanzmann's thrombasthenia. J Clin Invest (1978) 1.05

Polymorphism of human platelet membrane glycoprotein IIb associated with the Baka/Bakb alloantigen system. Blood (1990) 1.05

Characterization of human platelet glycoprotein antigens giving rise to individual immunoprecipitates in crossed-immunoelectrophoresis. Blood (1981) 1.05

Human fibrinogen heterogeneities. 3. Identification of chain variants. J Biol Chem (1972) 1.04

The human platelet alloantigens Br(a) and Brb are associated with a single amino acid polymorphism on glycoprotein Ia (integrin subunit alpha 2). J Clin Invest (1993) 1.04

Identification and functional characterization of protein kinase C isozymes in platelets and HEL cells. J Biol Chem (1992) 1.03