Published in Blood on December 01, 1981
Platelets have more than one binding site for von Willebrand factor. J Clin Invest (1983) 2.89
Diagnosis of Bernard-Soulier syndrome and Glanzmann's thrombasthenia with a monoclonal assay on whole blood. J Clin Invest (1983) 1.40
Platelet glycoproteins Ia, Ic, and IIa are physicochemically indistinguishable from the very late activation antigens adhesion-related proteins of lymphocytes and other cell types. J Clin Invest (1988) 1.31
Glycoprotein Ic-IIa functions as an activation-independent fibronectin receptor on human platelets. J Cell Biol (1988) 1.13
A variant of Glanzmann's thrombasthenia with abnormal glycoprotein IIb-IIIa complexes in the platelet membrane. J Clin Invest (1987) 0.94
Endothelial cell synthesis of von Willebrand antigen II, von Willebrand factor, and von Willebrand factor/von Willebrand antigen II complex. J Clin Invest (1985) 0.94
Surface modifications in the platelets of a patient with alpha-N-acetyl-D-galactosamine residues, the Tn-syndrome. J Clin Invest (1982) 0.86
The phosphoprotein that regulates platelet Ca2+ transport is located on the plasma membrane, controls membrane-associated Ca2(+)-ATPase and is not glycoprotein Ib beta-subunit. Biochem J (1991) 0.78
Glanzmann's thrombasthenia: the spectrum of clinical disease. Blood (1990) 3.02
Bleeding in renal failure: a possible cause. Br Med J (1976) 2.82
Analysis of platelet membrane glycoprotein polymorphisms in Glanzmann thrombasthenia showed the French gypsy mutation in the alphaIIb gene to be strongly linked to the HPA-1b polymorphism in beta3. J Thromb Haemost (2003) 2.20
Interaction of AP-2, a monoclonal antibody specific for the human platelet glycoprotein IIb-IIIa complex, with intact platelets. J Biol Chem (1983) 2.09
An abnormal platelet glycoprotein pattern in three cases of Glanzmann's thrombasthenia. Br J Haematol (1974) 2.01
Ser-752-->Pro mutation in the cytoplasmic domain of integrin beta 3 subunit and defective activation of platelet integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) in a variant of Glanzmann thrombasthenia. Proc Natl Acad Sci U S A (1992) 1.95
The formation of Ca++-dependent complexes of platelet membrane glycoproteins IIb and IIIa in solution as determined by crossed immunoelectrophoresis. Blood (1981) 1.86
Aspirin resistance: position paper of the Working Group on Aspirin Resistance. J Thromb Haemost (2005) 1.83
Expression of platelet membrane glycoproteins and alpha-granule proteins by a human erythroleukemia cell line (HEL). EMBO J (1984) 1.82
On the association of glycoprotein Ib and actin-binding protein in human platelets. J Cell Biol (1985) 1.80
Molecular defects in interactions of platelets with the vessel wall. N Engl J Med (1984) 1.78
Specific roles for platelet surface glycoproteins in platelet function. Nature (1975) 1.77
Induction of megakaryocytes to synthesize and store a releasable pool of human factor VIII. J Thromb Haemost (2003) 1.74
The different glycoprotein abnormalities in thrombasthenic and Bernard-Soulier platelets. Semin Hematol (1979) 1.71
Platelet surface glycoproteins. Studies on resting and activated platelets and platelet membrane microparticles in normal subjects, and observations in patients during adult respiratory distress syndrome and cardiac surgery. J Clin Invest (1986) 1.71
Topography of ligand-induced binding sites, including a novel cation-sensitive epitope (AP5) at the amino terminus, of the human integrin beta 3 subunit. J Biol Chem (1995) 1.70
Analysis of the glycoprotein and protein composition of Bernard-Soulier platelets by single and two-dimensional sodium dodecyl sulfate-polyacrylamide gel electrophoresis. J Clin Invest (1981) 1.62
Bernard-Soulier syndrome: a new platelet glycoprotein abnormality. Its relationship with platelet adhesion to subendothelium and with the factor VIII von Willebrand protein. J Lab Clin Med (1976) 1.58
Quantitation of membrane glycoprotein IIIa on intact human platelets using the monoclonal antibody, AP-3. Blood (1985) 1.54
A study of variables affecting the quality of platelets stored at "room temperature". Transfusion (1976) 1.52
Nucleotide polymorphisms in the alpha2 gene define multiple alleles that are associated with differences in platelet alpha2 beta1 density. Blood (1998) 1.51
Annexin V as a probe of aminophospholipid exposure and platelet membrane vesiculation: a flow cytometry study showing a role for free sulfhydryl groups. Blood (1993) 1.48
Acquired IgG antibody occurring in a thrombasthenic patient: its effect on human platelet function. Blood (1978) 1.47
Platelet-released growth factors enhance the secretion of hyaluronic acid and induce hepatocyte growth factor production by synovial fibroblasts from arthritic patients. Rheumatology (Oxford) (2007) 1.41
Diagnosis of Bernard-Soulier syndrome and Glanzmann's thrombasthenia with a monoclonal assay on whole blood. J Clin Invest (1983) 1.40
Carboxyterminal peptides with the dimeric form of PF4 retain the inhibitory effect on the growth of human megakaryoblastic cell lines. J Lab Clin Med (1996) 1.39
European Working Group on Clinical Cell Analysis: Consensus protocol for the flow cytometric characterisation of platelet function. Thromb Haemost (1998) 1.37
A molecular defect in thrombasthenic platelets. J Clin Invest (1975) 1.36
Divalent cation regulation of the surface orientation of platelet membrane glycoprotein IIb. Correlation with fibrinogen binding function and definition of a novel variant of Glanzmann's thrombasthenia. J Clin Invest (1986) 1.35
Effect of calcium on the stability of the platelet membrane glycoprotein IIb-IIIa complex. J Biol Chem (1985) 1.31
Increased adhesion of erythrocytes to endothelial cells in diabetes mellitus and its relation to vascular complications. N Engl J Med (1981) 1.24
Independent modulation of von Willebrand factor and fibrinogen binding to the platelet membrane glycoprotein IIb/IIIa complex as demonstrated by monoclonal antibody. J Clin Invest (1985) 1.23
Isolation and immunologic characterization of the human platelet alloantigen, P1A1. Mol Immunol (1979) 1.21
Interaction of integrins alpha v beta 3 and glycoprotein IIb-IIIa with fibrinogen. Differential peptide recognition accounts for distinct binding sites. J Biol Chem (1990) 1.21
Monoclonal antibody to human platelet glycoprotein I. II. Effects on human platelet function. Br J Haematol (1981) 1.15
Absence of the platelet receptor for drug-dependent antibodies in the Bernard-Soulier syndrome. J Clin Invest (1978) 1.14
Glycoprotein Ic-IIa functions as an activation-independent fibronectin receptor on human platelets. J Cell Biol (1988) 1.13
Effect of prostacyclin (PGI2) on platelet adhesion to rabbit arterial subendothelium. Prostaglandins (1978) 1.11
A molecular model of RGD ligands. Antibody D gene segments that direct specificity for the integrin alpha IIb beta 3. J Biol Chem (1992) 1.11
Induction of acetylcholinesterase expression during apoptosis in various cell types. Cell Death Differ (2002) 1.10
Synthesis by cultured human umbilical vein endothelial cells of two proteins structurally and immunologically related to platelet membrane glycoproteins IIb and IIIa. J Cell Biol (1986) 1.10
Specific protein and glycoprotein deficiencies in platelets isolated from two patients with the gray platelet syndrome. Blood (1982) 1.10
Platelet aggregation in mammalians (human, rat, rabbit, guinea-pig, horse, dog). A comparative study. Thromb Diath Haemorrh (1967) 1.10
Cleavage of human von Willebrand factor by platelet calcium-activated protease. Blood (1985) 1.09
Inhibition of in vitro angiogenesis by platelet factor-4-derived peptides and mechanism of action. Blood (1999) 1.09
Differential distribution of von Willebrand factor in endothelial cells. Comparison between normal pigs and pigs with von Willebrand disease. Arteriosclerosis (1987) 1.09
Localization of internal pools of membrane glycoproteins involved in platelet adhesive responses. Am J Pathol (1986) 1.09
Platelet factor 4 modulates fibroblast growth factor 2 (FGF-2) activity and inhibits FGF-2 dimerization. Blood (1998) 1.08
Association of fibrinogen-bound glycoprotein IIb-IIIa complexes on the activated platelet surface. J Lab Clin Med (1996) 1.07
Involvement of platelet glycoprotein IIb-IIIa (alpha IIb-beta 3 integrin) in thrombin-induced synthesis of phosphatidylinositol 3',4'-bisphosphate. J Biol Chem (1991) 1.06
Human platelet fibrinogen: purification and hemostatic properties. Blood (1985) 1.05
Clopidogrel: a review of its mechanism of action. Platelets (1998) 1.05
Deletion of the platelet-specific alloantigen PlA1 from platelets in Glanzmann's thrombasthenia. J Clin Invest (1978) 1.05
Calcium involvement in aminophospholipid exposure and microparticle formation during platelet activation: a study using Ca2+-ATPase inhibitors. Biochemistry (1995) 1.05
Detection of heterozygotes in both parents of homozygous patients with Von Willebrand's disease. J Clin Pathol (1975) 1.04
Gray platelet syndrome: alpha-granule deficiency. Its influence on platelet function. J Lab Clin Med (1981) 1.03
Evaluation of the inhibition by heparin and hirudin of coagulation activation during r-tPA-induced thrombolysis. Blood (1989) 1.03
Effects of monoclonal antibodies against the platelet glycoprotein IIb/IIIa complex on thrombosis and hemostasis in the baboon. J Clin Invest (1988) 1.03
A glycoprotein I defect in the platelets of three patients with severe cirrhosis of the liver. Thromb Res (1978) 1.02
Calcium influx is a determining factor of calpain activation and microparticle formation in platelets. Eur J Biochem (1996) 1.02
Interaction of blood platelets with a microfibrillar extract from adult bovine aorta: requirement for von Willebrand factor. Proc Natl Acad Sci U S A (1983) 1.02
On the association of the platelet-specific alloantigen, Pena, with glycoprotein IIIa. Evidence for heterogeneity of glycoprotein IIIa. J Clin Invest (1987) 1.02
Synergistic action of two murine monoclonal antibodies that inhibit ADP-induced platelet aggregation without blocking fibrinogen binding. Blood (1987) 1.01
Platelet factor 4 and other CXC chemokines support the survival of normal hematopoietic cells and reduce the chemosensitivity of cells to cytotoxic agents. Blood (1997) 1.00
Gray platelet syndrome. Demonstration of alpha granule membranes that can fuse with the cell surface. J Clin Invest (1987) 1.00
Relationship between fibrinogen binding and the platelet glycoprotein deficiencies in Glanzmann's thrombasthenia type I and type II. Br J Haematol (1981) 1.00
Immunocytochemical study of the binding of fibrinogen and thrombospondin to ADP- and thrombin-stimulated human platelets. Blood (1985) 1.00
Further studies of the human platelet receptor for quinine- and quinine-dependent antibodies. J Immunol (1981) 1.00
A new variant of Glanzmann's thrombasthenia (Strasbourg I). Platelets with functionally defective glycoprotein IIb-IIIa complexes and a glycoprotein IIIa 214Arg----214Trp mutation. J Clin Invest (1992) 1.00
Galactosyltransferase and membrane glycoprotein abnormality in human platelets from Tn-syndrome donors. Nature (1979) 0.99
Molecular defects of platelets in Bernard-Soulier syndrome. Blood Cells (1983) 0.98
Interaction between platelets and von Willebrand factor provides a new scheme for primary haemostasis. Nat New Biol (1973) 0.98
Association of the platelet glycoprotein Ia C807T gene polymorphism with nonfatal myocardial infarction in younger patients. Blood (1999) 0.98
Response of human platelets to activating monoclonal antibodies: importance of Fc gamma RII (CD32) phenotype and level of expression. Blood (1992) 0.98
Fibrinogen Dusart: electron microscopy of molecules, fibers and clots, and viscoelastic properties of clots. Biophys J (1996) 0.97