Published in Br J Haematol on November 01, 1979
Deoxygenation permeabilizes sickle cell anaemia red cells to magnesium and reverses its gradient in the dense cells. J Physiol (1990) 1.21
Kinetics of increased deformability of deoxygenated sickle cells upon oxygenation. Biophys J (2003) 0.96
Potential use of biaromatic L-phenylalanyl derivatives as therapeutic agents in the treatment of sickle cell disease. Proc Natl Acad Sci U S A (1984) 0.78
Strain energy function of red blood cell membranes. Biophys J (1973) 6.05
Theoretical and experimental studies on viscoelastic properties of erythrocyte membrane. Biophys J (1978) 4.27
Dietary methods research in the third National Health and Nutrition Examination Survey: underreporting of energy intake. Am J Clin Nutr (1997) 3.75
Passive mechanical properties of human leukocytes. Biophys J (1981) 3.63
Regulation of cardiac gene expression during myocardial growth and hypertrophy: molecular studies of an adaptive physiologic response. FASEB J (1991) 3.29
Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment. EMBO J (2001) 3.22
Morphometry of human leukocytes. Blood (1980) 3.07
Canagliflozin, a novel inhibitor of sodium glucose co-transporter 2, dose dependently reduces calculated renal threshold for glucose excretion and increases urinary glucose excretion in healthy subjects. Diabetes Obes Metab (2011) 3.00
A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster. Genome Res (2001) 2.73
Flow Characteristics of Human Erythrocytes through Polycarbonate Sieves. Science (1967) 2.61
Design and construction of a linear shear stress flow chamber. Ann Biomed Eng (1993) 2.57
Blood viscosity: influence of erythrocyte deformation. Science (1967) 2.55
Mechanotransduction in response to shear stress. Roles of receptor tyrosine kinases, integrins, and Shc. J Biol Chem (1999) 2.51
The interaction of leukocytes and erythrocytes in capillary and postcapillary vessels. Microvasc Res (1980) 2.49
Effects of hematocrit and plasma proteins on human blood rheology at low shear rates. J Appl Physiol (1966) 2.45
Abnormal rheology of oxygenated blood in sickle cell anemia. J Clin Invest (1970) 2.42
Integrin-mediated mechanotransduction requires its dynamic interaction with specific extracellular matrix (ECM) ligands. Proc Natl Acad Sci U S A (2001) 2.40
Elastic deformations of red blood cells. J Biomech (1977) 2.34
Fluid shear stress activation of focal adhesion kinase. Linking to mitogen-activated protein kinases. J Biol Chem (1997) 2.34
Role of surface electric charge in red blood cell interactions. J Gen Physiol (1973) 2.33
Structure of sickled erythrocytes and of sickle-cell hemoglobin fibers. Proc Natl Acad Sci U S A (1973) 2.32
Shear stress induces spatial reorganization of the endothelial cell cytoskeleton. Cell Motil Cytoskeleton (1998) 2.29
Leukocyte relaxation properties. Biophys J (1988) 2.27
Estimation of oxygen delivery in newborns with a univentricular circulation. Circulation (1998) 2.26
The role of phospholipase D and phosphatidic acid in the mechanical activation of mTOR signaling in skeletal muscle. Proc Natl Acad Sci U S A (2006) 2.19
In vivo measurements of "apparent viscosity" and microvessel hematocrit in the mesentery of the cat. Microvasc Res (1980) 2.16
Red cell deformability and its relevance to blood flow. Annu Rev Physiol (1987) 2.15
Irreversibly sickled erythrocytes: a consequence of the heterogeneous distribution of hemoglobin types in sickle-cell anemia. J Clin Invest (1968) 2.06
Passive deformation analysis of human leukocytes. J Biomech Eng (1988) 2.03
Alteration in the rheologic properties of Plasmodium knowlesi--infected red cells. A possible mechanism for capillary obstruction. J Clin Invest (1971) 2.01
Fluid shear stress induces a biphasic response of human monocyte chemotactic protein 1 gene expression in vascular endothelium. Proc Natl Acad Sci U S A (1994) 1.96
Cell distribution in capillary networks. Microvasc Res (1980) 1.91
Erythrocyte Hb-S concentration. An important factor in the low oxygen affinity of blood in sickle cell anemia. J Clin Invest (1973) 1.91
Determination of junction avidity of cytolytic T cell and target cell. Science (1986) 1.88
DNA microarray analysis of gene expression in endothelial cells in response to 24-h shear stress. Physiol Genomics (2001) 1.85
Molecular mechanism of endothelial growth arrest by laminar shear stress. Proc Natl Acad Sci U S A (2000) 1.83
Blood viscosity: influence of erythrocyte aggregation. Science (1967) 1.80
Influence of physicochemical factors on rheology of human neutrophils. Biophys J (1982) 1.80
Impaired expansion of mouse B cell progenitors lacking Btk. Immunity (1995) 1.79
Direct relationship between blood pressure and blood viscosity in normal and hypertensive subjects. Role of fibrinogen and concentration. Am J Med (1981) 1.75
Control of B cell production by the adaptor protein lnk. Definition Of a conserved family of signal-modulating proteins. Immunity (2000) 1.74
Intermolecular organization of deoxygenated sickle haemoglobin determined by x-ray diffraction. Nature (1972) 1.74
Ultrastructural basis of the mechanism of rouleaux formation. Microvasc Res (1973) 1.72
Endothelial cellular response to altered shear stress. Am J Physiol Lung Cell Mol Physiol (2001) 1.68
Measurement of orientation and distribution of cellular alignment and cytoskeletal organization. Ann Biomed Eng (2000) 1.67
Hemoglobin interaction: modification of solid phase composition in the sickling phenomenon. Science (1970) 1.64
Distinct roles for the small GTPases Cdc42 and Rho in endothelial responses to shear stress. J Clin Invest (1999) 1.62
Dynamic contact forces on leukocyte microvilli and their penetration of the endothelial glycocalyx. Biophys J (2001) 1.58
Possible role of increased blood viscosity in the hemodynamics of systemic hypertension. Am J Cardiol (2000) 1.58
Role of the sympathetic nervous system in hemorrhage. Physiol Rev (1967) 1.55
An elastic network model based on the structure of the red blood cell membrane skeleton. Biophys J (1996) 1.49
Shear stress induces a time- and position-dependent increase in endothelial cell membrane fluidity. Am J Physiol Cell Physiol (2001) 1.49
Identifying characteristics of the haematopoietic precursor cell. J Cell Sci (1971) 1.49
The Ras-JNK pathway is involved in shear-induced gene expression. Mol Cell Biol (1996) 1.47
The cis-acting phorbol ester "12-O-tetradecanoylphorbol 13-acetate"-responsive element is involved in shear stress-induced monocyte chemotactic protein 1 gene expression. Proc Natl Acad Sci U S A (1995) 1.47
Role of integrins in cellular responses to mechanical stress and adhesion. Curr Opin Cell Biol (1997) 1.46
Shear stress activates p60src-Ras-MAPK signaling pathways in vascular endothelial cells. Arterioscler Thromb Vasc Biol (1998) 1.46
Viscoelastic properties of leukocytes. Kroc Found Ser (1984) 1.45
Effects of disturbed flow on endothelial cells. J Biomech Eng (1998) 1.44
Reversible and irreversible sickling: a distinction by electron microscopy. Blood (1969) 1.42
Quantitative relationship between Heinz body formation and red blood cell deformability. Blood (1986) 1.39
Relation of blood viscosity to demographic and physiologic variables and to cardiovascular risk factors in apparently normal adults. Circulation (1990) 1.39
Observations on blood viscosity changes after acute myocardial infarction. Circulation (1975) 1.38
Shear dependence of effective cell volume as a determinant of blood viscosity. Science (1970) 1.38
Thermodynamic studies of polymerization of deoxygenated sickle cell hemoglobin. Proc Natl Acad Sci U S A (1976) 1.37
Mechanics of Rouleau formation. Biophys J (1981) 1.37
Colloidal gold--low density lipoprotein conjugates as membrane receptor probes. Proc Natl Acad Sci U S A (1981) 1.36
Shear stress induction of the tissue factor gene. J Clin Invest (1997) 1.35
Quantitative studies on the influence of leukocytes on the vascular resistance in a skeletal muscle preparation. Microvasc Res (1984) 1.34
Fluid shear stress activation of IkappaB kinase is integrin-dependent. J Biol Chem (1998) 1.33
Heat shock-induced necrosis and apoptosis in osteoblasts. J Orthop Res (1999) 1.30
Hemolysis during filtration through micropores: a scanning electron microscopic and hemorheologic correlation. Microvasc Res (1971) 1.30
Effects of flow patterns on endothelial cell migration into a zone of mechanical denudation. Biochem Biophys Res Commun (2001) 1.30
The physical state of hemoglobin in sickle-cell anemia erythrocytes in vivo. J Exp Med (1968) 1.29
Locomotion forces generated by a polymorphonuclear leukocyte. Biophys J (1992) 1.28
Influence of the ionic composition of fluid medium on red cell aggregation. J Gen Physiol (1973) 1.27
A stochastic model of leukocyte rolling. Biophys J (1995) 1.27
Elevated blood viscosity in patients with borderline essential hypertension. Hypertension (1983) 1.24
Effects of lipoproteins on plasma viscosity. Atherosclerosis (1981) 1.24
Red cell aggregation by macromolecules: roles of surface adsorption and electrostatic repulsion. J Supramol Struct (1973) 1.22
Human fetal hemoglobin: significance in disease. Ann N Y Acad Sci (1974) 1.21
Decreased deformability of Plasmodium coatneyi-infected red cells and its possible relation to cerebral malaria. Am J Trop Med Hyg (1972) 1.21
Intermolecular interactions of oxygenated sickle hemoglobin molecules in cells and cell-free solutions. Biophys J (1976) 1.20
Tissue-blood partition coefficient for xenon: temperature and hematocrit dependence. J Appl Physiol Respir Environ Exerc Physiol (1980) 1.17
Influence of network topology on the elasticity of the red blood cell membrane skeleton. Biophys J (1997) 1.16
Nephrotic syndrome: vasoconstriction and hypervolemic types indicated by renin-sodium profiling. Ann Intern Med (1979) 1.15
Energy balance in red cell interactions. Ann N Y Acad Sci (1983) 1.14
Role of dying endothelial cells in transendothelial macromolecular transport. Arteriosclerosis (1990) 1.14
Effects of hematocrit variations on regional hemodynamics and oxygen transport in the dog. Am J Physiol (1980) 1.14
Density distribution of red cells infected by Plasmodium knowlesi and plasmodium coatneyi. Exp Parasitol (1971) 1.13
Determination of aggregation force in rouleaux by fluid mechanical technique. Microvasc Res (1977) 1.13
Deformability of sickle cells as studied by microsieving. J Lab Clin Med (1975) 1.11
Changes in blood viscosity accompanying the response to prazosin in patients with essential hypertension. J Cardiovasc Pharmacol (1980) 1.11
The hyperlipidemia of the nephrotic syndrome. Relation to plasma albumin concentration, oncotic pressure, and viscosity. N Engl J Med (1985) 1.09
Theoretical and experimental studies on cross-bridge migration during cell disaggregation. Biophys J (1989) 1.09
Influence of cholesterol content on red cell membrane viscoelasticity and fluidity. Biophys J (1983) 1.09
Shear-dependent interaction of plasma proteins with erythrocytes in blood rheology. Am J Physiol (1970) 1.09
Effect of cell turnover and leaky junctions on arterial macromolecular transport. Am J Physiol (1985) 1.09