Published in Cell on December 01, 1985
Specific antiviral activity of a poly(L-lysine)-conjugated oligodeoxyribonucleotide sequence complementary to vesicular stomatitis virus N protein mRNA initiation site. Proc Natl Acad Sci U S A (1987) 3.00
Antisense RNA of proto-oncogene c-fos blocks renewed growth of quiescent 3T3 cells. Mol Cell Biol (1987) 2.97
A semi-dominant allele, niv-525, acts in trans to inhibit expression of its wild-type homologue in Antirrhinum majus. EMBO J (1988) 2.89
Inhibition of gene expression in plant cells by expression of antisense RNA. Proc Natl Acad Sci U S A (1986) 2.43
Enzymatic amplification of translation inhibition of rabbit beta-globin mRNA mediated by anti-messenger oligodeoxynucleotides covalently linked to intercalating agents. Nucleic Acids Res (1987) 2.41
Establishment of a transient expression system for Dictyostelium discoideum. Nucleic Acids Res (1988) 2.30
RNAi in Dictyostelium: the role of RNA-directed RNA polymerases and double-stranded RNase. Mol Biol Cell (2002) 1.92
Cell cycle expression of RNA duplex unwindase activity in mammalian cells. Mol Cell Biol (1988) 1.86
Molecular complementation of a genetic marker in Dictyostelium using a genomic DNA library. Proc Natl Acad Sci U S A (1989) 1.84
Homologous recombination in the Dictyostelium alpha-actinin gene leads to an altered mRNA and lack of the protein. EMBO J (1987) 1.79
Antisense oligonucleotide-directed cleavage of mRNA in Xenopus oocytes and eggs. EMBO J (1988) 1.75
Silencing of retrotransposons in Dictyostelium by DNA methylation and RNAi. Nucleic Acids Res (2005) 1.63
Retracted Loss of (2'-5')oligoadenylate synthetase activity by production of antisense RNA results in lack of protection by interferon from viral infections. Proc Natl Acad Sci U S A (1987) 1.57
Stable and heritable inhibition of the expression of nopaline synthase in tobacco expressing antisense RNA. Proc Natl Acad Sci U S A (1987) 1.41
Novel non-coding RNAs in Dictyostelium discoideum and their expression during development. Nucleic Acids Res (2004) 1.35
Expression of chimeric tRNA-driven antisense transcripts renders NIH 3T3 cells highly resistant to Moloney murine leukemia virus replication. Mol Cell Biol (1990) 1.34
Inhibition of Rous sarcoma virus replication by antisense RNA. J Virol (1987) 1.26
Inhibition of SV40 replicon function by engineered antisense RNA transcribed by RNA polymerase III. EMBO J (1987) 1.23
Surface cAMP receptors mediate multiple responses during development in Dictyostelium: evidenced by antisense mutagenesis. J Cell Biol (1990) 1.16
A stable bifunctional antisense transcript inhibiting gene expression in transgenic plants. Proc Natl Acad Sci U S A (1988) 1.16
Regulatory sequences in the promoter of the Dictyostelium Actin 6 gene. EMBO J (1986) 1.15
Inducible expression of calmodulin antisense RNA in Dictyostelium cells inhibits the completion of cytokinesis. Mol Biol Cell (1992) 1.15
Inhibition of retroviral replication by anti-sense RNA. Mol Cell Biol (1986) 1.13
Conserved pattern of antisense overlapping transcription in the homologous human ERCC-1 and yeast RAD10 DNA repair gene regions. Mol Cell Biol (1989) 1.10
Molecular cloning of casein kinase II alpha subunit from Dictyostelium discoideum and its expression in the life cycle. Mol Cell Biol (1992) 1.08
Transcriptional regulation by folate: inducible gene expression in Dictyostelium transformants during growth and early development. Nucleic Acids Res (1992) 1.06
The alpha protein ICP0 does not appear to play a major role in the regulation of herpes simplex virus gene expression during infection in tissue culture. Nucleic Acids Res (1987) 1.06
Stable repression of ribosomal protein L1 synthesis in Xenopus oocytes by microinjection of antisense RNA. Proc Natl Acad Sci U S A (1986) 1.05
Identification of regions essential for extrachromosomal replication and maintenance of an endogenous plasmid in Dictyostelium. Nucleic Acids Res (1988) 1.05
Genetics of early Dictyostelium discoideum development. Microbiol Rev (1988) 1.04
Mutagenesis and gene identification in Dictyostelium by shotgun antisense. Proc Natl Acad Sci U S A (1996) 1.03
Regulation of the Discoidin I gamma gene in Dictyostelium discoideum: identification of individual promoter elements mediating induction of transcription and repression by cyclic AMP. Mol Cell Biol (1990) 1.02
Antisense ribosomal protein gene expression specifically disrupts oogenesis in Drosophila melanogaster. Proc Natl Acad Sci U S A (1988) 1.00
Amino acid substitutions in the Dictyostelium G alpha subunit G alpha 2 produce dominant negative phenotypes and inhibit the activation of adenylyl cyclase, guanylyl cyclase, and phospholipase C. Mol Biol Cell (1992) 0.99
Both RNA level and translation efficiency are reduced by anti-sense RNA in transgenic tobacco. Nucleic Acids Res (1989) 0.97
Effect of protein synthesis inhibition on gene expression during early development of Dictyostelium discoideum. Mol Cell Biol (1988) 0.97
Antisense RNA complementary to 3' coding and noncoding sequences of creatine kinase is a potent inhibitor of translation in vivo. Proc Natl Acad Sci U S A (1989) 0.95
Extrachromosomal, homologous expression of trypanothione reductase and its complementary mRNA in Trypanosoma cruzi. Nucleic Acids Res (1996) 0.94
Suppression of endo B cytokeratin by its antisense RNA inhibits the normal coexpression of endo A cytokeratin. Proc Natl Acad Sci U S A (1987) 0.94
A developmentally regulated membrane protein gene in Dictyostelium discoideum is also induced by heat shock and cold shock. Mol Cell Biol (1988) 0.93
Dictyostelium discoideum myosin: isolation and characterization of cDNAs encoding the essential light chain. Mol Cell Biol (1988) 0.91
The conditional inhibition of gene expression in cultured Drosophila cells by antisense RNA. Nucleic Acids Res (1989) 0.90
Genetic and physiologic modulation of the prestarvation response in Dictyostelium discoideum. Mol Biol Cell (1995) 0.90
The effects of transcription on the nucleosome structure of four Dictyostelium genes. Nucleic Acids Res (1989) 0.89
Nuclear and cytoplasmic sites for anti-sense control. Nucleic Acids Res (1989) 0.88
Inhibition of human T-cell leukemia virus type I replication in primary human T cells that express antisense RNA. J Virol (1989) 0.88
Multiple regulatory genes control expression of a gene family during development of Dictyostelium discoideum. Mol Cell Biol (1986) 0.85
gdt1, a new signal transduction component for negative regulation of the growth-differentiation transition in Dictyostelium discoideum. Mol Biol Cell (2000) 0.85
Antagonistic effects of signal transduction by intracellular and extracellular cAMP on gene regulation in Dictyostelium. Mol Biol Cell (1996) 0.85
HelF, a putative RNA helicase acts as a nuclear suppressor of RNAi but not antisense mediated gene silencing. Nucleic Acids Res (2006) 0.84
A cell number-counting factor regulates levels of a novel protein, SslA, as part of a group size regulation mechanism in Dictyostelium. Eukaryot Cell (2007) 0.84
Treasure hunt in an amoeba: non-coding RNAs in Dictyostelium discoideum. Curr Genet (2007) 0.83
motA1552, a mutation of Dictyostelium discoideum having pleiotropic effects on motility and discoidin I regulation. Genetics (1988) 0.82
Concentration-affinity equivalence in gene regulation: convergence of genetic and environmental effects. Proc Natl Acad Sci U S A (1988) 0.82
Cell adhesion molecule DdCAD-1 is imported into contractile vacuoles by membrane invagination in a Ca2+- and conformation-dependent manner. J Biol Chem (2009) 0.82
The discoidin I gene family of Dictyostelium discoideum is linked to genes regulating its expression. Genetics (1988) 0.80
Discoidin I from Dictyostelium discoideum and Interactions with oligosaccharides: specificity, affinity, crystal structures, and comparison with discoidin II. J Mol Biol (2010) 0.80
Translational control of discoidin lectin expression in drsA suppressor mutants of Dictyostelium discoideum. Mol Cell Biol (1991) 0.78
Cooperative cell motility during tandem locomotion of amoeboid cells. Mol Biol Cell (2016) 0.78
Use of a transactive regulatory mutant of Dictyostelium discoideum in a eucaryotic expression system. Nucleic Acids Res (1993) 0.78
The protein domains of the Dictyostelium microprocessor that are required for correct subcellular localization and for microRNA maturation. RNA Biol (2016) 0.76
A Simple Retroelement Based Knock-Down System in Dictyostelium: Further Insights into RNA Interference Mechanisms. PLoS One (2015) 0.76
Evidence for a feedback regulated back-up promoter which controls permanent expression of a Dictyostelium gene. Nucleic Acids Res (1990) 0.75
Inhibition of SV40 gene expression by microinjected small antisense RNA and DNA molecules. Nucleic Acids Res (1991) 0.75
Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium. EMBO J (1999) 4.34
Differential expression and 5' end mapping of actin genes in Dictyostelium. Cell (1981) 3.60
DNA-mediated transformation in Dictyostelium discoideum: regulated expression of an actin gene fusion. Mol Cell Biol (1984) 3.37
Induction and modulation of cell-type-specific gene expression in Dictyostelium. Cell (1983) 3.16
Developmental regulation of a Dictyostelium gene encoding a protein homologous to mammalian ras protein. Cell (1984) 3.14
Role of phosphatidylinositol 3' kinase and a downstream pleckstrin homology domain-containing protein in controlling chemotaxis in dictyostelium. J Cell Biol (2001) 3.03
Molecular biology in Dictyostelium: tools and applications. Methods Cell Biol (1987) 2.80
Identification and analysis of Dictyostelium actin genes, a family of moderately repeated genes. Cell (1978) 2.79
Heat shock proteins are methylated in avian and mammalian cells. Proc Natl Acad Sci U S A (1981) 2.68
Unusual nucleotide sequences at the 5' end of actin genes in Dictyostelium discoideum. Proc Natl Acad Sci U S A (1979) 2.64
Signaling pathways controlling cell polarity and chemotaxis. Trends Biochem Sci (2001) 2.58
Sequence organization in Dictyostelium: unique structure at the 5'-ends of protein coding genes. Nucleic Acids Res (1983) 2.32
Establishment of a transient expression system for Dictyostelium discoideum. Nucleic Acids Res (1988) 2.30
Isolation of developmentally regulated genes from Dictyostelium. Dev Biol (1980) 2.17
Sequence and expression of the discoidin I gene family in Dictyostelium discoideum. J Mol Biol (1981) 2.16
High-copy-number transformants and co-transformation in Dictyostelium. Gene (1985) 2.16
Characterization of the genome of the cellular slime mold Dictyostelium discoideum. J Mol Biol (1972) 2.10
Control of cell polarity and chemotaxis by Akt/PKB and PI3 kinase through the regulation of PAKa. Mol Cell (2001) 2.07
Regulation and function of G alpha protein subunits in Dictyostelium. Cell (1989) 2.03
Optimization and in situ detection of Escherichia coli beta-galactosidase gene expression in Dictyostelium discoideum. Gene (1989) 2.02
A small nuclear precursor of messenger RNA in the cellular slime mold Dictyostelium discoideum. J Mol Biol (1973) 2.01
Differential antisense transcription from the Dictyostelium EB4 gene locus: implications on antisense-mediated regulation of mRNA stability. Cell (1992) 1.98
Multigene families encoding actin and tubulin. Cell (1981) 1.96
Changes in the expression of single-copy DNA during development of the cellular slime mold Dictyostelium discoideum. J Mol Biol (1972) 1.93
PAKa, a putative PAK family member, is required for cytokinesis and the regulation of the cytoskeleton in Dictyostelium discoideum cells during chemotaxis. J Cell Biol (1999) 1.89
Actin genes and actin messenger RNA in Acanthamoeba castellanii. Nucleotide sequence of the split actin gene I. J Mol Biol (1982) 1.89
Multiple, heterogeneous actin genes in Dictyostelium. Cell (1978) 1.87
Evidence for sub-families of actin genes in Dictyostelium as determined by comparisons of 3' end sequences. J Mol Biol (1981) 1.85
Molecular complementation of a genetic marker in Dictyostelium using a genomic DNA library. Proc Natl Acad Sci U S A (1989) 1.84
Intervening sequences in a Dictyostelium gene that encodes a low abundance class mRNA. Nucleic Acids Res (1980) 1.82
The degradation of ribonucleic acids injected into Xenopus laevis oocytes. Cell (1974) 1.80
A DNA-mediated transformation system for Dictyostelium discoideum. Proc Natl Acad Sci U S A (1982) 1.80
Homologous recombination in the Dictyostelium alpha-actinin gene leads to an altered mRNA and lack of the protein. EMBO J (1987) 1.79
Identification of the sequences controlling cyclic AMP regulation and cell-type-specific expression of a prestalk-specific gene in Dictyostelium discoideum. Mol Cell Biol (1987) 1.78
A MAP kinase necessary for receptor-mediated activation of adenylyl cyclase in Dictyostelium. J Cell Biol (1995) 1.77
LagC is required for cell-cell interactions that are essential for cell-type differentiation in Dictyostelium. Genes Dev (1994) 1.76
Molecular genetic analysis of two G alpha protein subunits in Dictyostelium. J Biol Chem (1991) 1.72
A secreted factor and cyclic AMP jointly regulate cell-type-specific gene expression in Dictyostelium discoideum. Mol Cell Biol (1985) 1.72
A novel Ras-interacting protein required for chemotaxis and cyclic adenosine monophosphate signal relay in Dictyostelium. Mol Biol Cell (1999) 1.72
Yeast is unable to excise foreign intervening sequences from hybrid gene transcripts. Proc Natl Acad Sci U S A (1983) 1.67
Analysis of G alpha 4, a G-protein subunit required for multicellular development in Dictyostelium. Genes Dev (1992) 1.66
A phosphatidylinositol (PI) kinase gene family in Dictyostelium discoideum: biological roles of putative mammalian p110 and yeast Vps34p PI 3-kinase homologs during growth and development. Mol Cell Biol (1995) 1.64
Isolation and hybridization kinetics of messenger RNA from Dictyostelium discoideum. Nat New Biol (1972) 1.63
A developmentally regulated, putative serine/threonine protein kinase is essential for development in Dictyostelium. Mech Dev (1991) 1.61
Analysis of the multigene family coding the developmentally regulated carbohydrate-binding protein discoidin-I in D. discoideum. Cell (1980) 1.60
A cell-counting factor regulating structure size in Dictyostelium. Genes Dev (1999) 1.59
Cyclic AMP regulation of early gene expression in Dictyostelium discoideum: mediation via the cell surface cyclic AMP receptor. Mol Cell Biol (1987) 1.58
A novel Akt/PKB-related kinase is essential for morphogenesis in Dictyostelium. Curr Biol (2000) 1.58
Developmentally regulated proteins of the plasma membrane of Dictyostelium discoideum. The carbohydrate-binding protein. J Mol Biol (1976) 1.53
Signal transduction pathways leading to spore differentiation in Dictyostelium discoideum. Dev Biol (1998) 1.50
Cloning and characterization of the G-box binding factor, an essential component of the developmental switch between early and late development in Dictyostelium. Genes Dev (1994) 1.49
A family of short, interspersed repeat sequences at the 5' end of a set of Dictyostelium single-copy mRNAs. Cell (1979) 1.48
Role of Rac in controlling the actin cytoskeleton and chemotaxis in motile cells. Proc Natl Acad Sci U S A (2000) 1.46
Structural organization of the genome of Dictyostelium discoideum: analysis by EcoR1 restriction endonuclease. J Mol Biol (1976) 1.45
Determination of preferential binding sites for anti-dsRNA antibodies on double-stranded RNA by scanning force microscopy. RNA (2000) 1.43
A density-sensing factor controls development in Dictyostelium. Genes Dev (1992) 1.39
Cell-autonomous determination of cell-type choice in Dictyostelium development by cell-cycle phase. Science (1987) 1.37
Transcription of polydeoxythymidylate sequences in the genome of the cellular slime mold, Dictyostelium discoideum. Proc Natl Acad Sci U S A (1974) 1.35
Seven helix chemoattractant receptors transiently stimulate mitogen-activated protein kinase in Dictyostelium. Role of heterotrimeric G proteins. J Biol Chem (1996) 1.34
Phenotypic changes induced by a mutated ras gene during the development of Dictyostelium transformants. Nature (1986) 1.33
The structure of M6, a recombinant plasmid containing Dictyostelium DNA homologous to actin messenger RNA. Cell (1978) 1.33
Multiple alpha subunits of guanine nucleotide-binding proteins in Dictyostelium. Proc Natl Acad Sci U S A (1989) 1.32
A secreted 80 x 10(3) Mr protein mediates sensing of cell density and the onset of development in Dictyostelium. Development (1991) 1.31
Tyrosine phosphorylation of actin in Dictyostelium associated with cell-shape changes. Science (1993) 1.30
The G alpha subunit G alpha 4 couples to pterin receptors and identifies a signaling pathway that is essential for multicellular development in Dictyostelium. Proc Natl Acad Sci U S A (1994) 1.30
A spatial gradient of expression of a cAMP-regulated prespore cell-type-specific gene in Dictyostelium. Genes Dev (1990) 1.30
Gene-specific expression of the actin multigene family of Dictyostelium discoideum. J Mol Biol (1985) 1.30
PSF and CMF, autocrine factors that regulate gene expression during growth and early development of Dictyostelium. Experientia (1995) 1.30
Organization of the actin multigene family of Dictyostelium discoideum and analysis of variability in the protein coding regions. J Mol Biol (1985) 1.28
Organization of the ribosomal RNA genes of Dictyostelium discoideum: mapping of the nontranscribed spacer regions. Cell (1976) 1.28
An unusual transposon encoding heat shock inducible and developmentally regulated transcripts in Dictyostelium. Cell (1983) 1.26
Genomic instability and mobile genetic elements in regions surrounding two discoidin I genes of Dictyostelium discoideum. Mol Cell Biol (1984) 1.26
A density-sensing factor regulates signal transduction in Dictyostelium. J Cell Biol (1995) 1.26
The Dictyostelium MAP kinase kinase DdMEK1 regulates chemotaxis and is essential for chemoattractant-mediated activation of guanylyl cyclase. EMBO J (1997) 1.25
Organization of the Dictyostelium discoideum actin multigene family. Flanking sequences show subfamily homologies and unusual dyad symmetries. J Mol Biol (1985) 1.25
Ribonucleoprotein particles containing heterogeneous nuclear RNA in the cellular slime mold Dictyostelium discoideum. Proc Natl Acad Sci U S A (1975) 1.25
Regulated protein degradation controls PKA function and cell-type differentiation in Dictyostelium. Genes Dev (2001) 1.24
A trans-acting regulatory product necessary for expression of the Drosophila melanogaster 68C glue gene cluster. Cell (1984) 1.23
Spatial and temporal regulation of a foreign gene by a prestalk-specific promoter in transformed Dictyostelium discoideum. Mol Cell Biol (1986) 1.23
Actinomycin D and the regulation of enzyme biosynthesis during development of Dictyostelium discoideum. J Mol Biol (1973) 1.23
Synthesis of messenger and ribosomal RNA precursors in isolated nuclei of the cellular slime mold Dictyostelium discoideum. J Mol Biol (1974) 1.23
The Dictyostelium MAP kinase ERK2 regulates multiple, independent developmental pathways. Genes Dev (1996) 1.22
cAMP and cell sorting control the spatial expression of a developmentally essential cell-type-specific ras gene in Dictyostelium. Genes Dev (1991) 1.22
Sequence organization and developmental expression of an interspersed, repetitive element and associated single-copy DNA sequences in Dictyostelium discoideum. Mol Cell Biol (1985) 1.21
Dictyostelium rDNA consists of non-chromosomal palindromic dimers containing 5S and 36S coding regions. Chromosoma (1978) 1.20
Analysis of a spatially regulated phosphotyrosine phosphatase identifies tyrosine phosphorylation as a key regulatory pathway in Dictyostelium. Cell (1992) 1.20
The membrane glycoprotein gp150 is encoded by the lagC gene and mediates cell-cell adhesion by heterophilic binding during Dictyostelium development. Dev Biol (2000) 1.20
The use of restriction fragment length polymorphisms and DNA duplications to study the organization of the actin multigene family in Dictyostelium discoideum. Genetics (1986) 1.19
Regulation of the synthesis of two carbohydrate-binding proteins in Dictyostelium discoideum. J Biol Chem (1978) 1.19
A precise group size in Dictyostelium is generated by a cell-counting factor modulating cell-cell adhesion. Mol Cell (2000) 1.18
Regulated expression of ras gene constructs in Dictyostelium transformants. Proc Natl Acad Sci U S A (1985) 1.16