Published in Cold Spring Harb Symp Quant Biol on January 01, 1977
Organization of immunoglobulin heavy chain genes and allelic deletion model. Proc Natl Acad Sci U S A (1978) 3.95
Multiple related immunoglobulin variable-region genes identified by cloning and sequence analysis. Proc Natl Acad Sci U S A (1978) 3.88
Transcription of mouse kappa chain genes: implications for allelic exclusion. Proc Natl Acad Sci U S A (1980) 3.38
Cloning of an immunoglobulin variable region gene from mouse embryo. Proc Natl Acad Sci U S A (1977) 3.21
Phase variation in Salmonella: genetic analysis of a recombinational switch. Proc Natl Acad Sci U S A (1979) 3.02
Variable and constant parts of the immunoglobulin light chain gene of a mouse myeloma cell are 1250 nontranslated bases apart. Proc Natl Acad Sci U S A (1977) 2.93
Exon shuffling generates an immunoglobulin heavy chain gene. Proc Natl Acad Sci U S A (1980) 2.80
DNA clones containing mouse immunoglobulin kappa chain genes isolated by in vitro packaging into phage lambda coats. Proc Natl Acad Sci U S A (1978) 2.60
DNA between variable and joining gene segments of immunoglobulin kappa light chain is frequently retained in cells that rearrange the kappa locus. Proc Natl Acad Sci U S A (1982) 2.36
A rearranged DNA sequence possibly related to the translocation of immunoglobulin gene segments. Nucleic Acids Res (1980) 2.31
Rearrangement of T-cell receptor beta-chain genes during T-cell development. Proc Natl Acad Sci U S A (1985) 2.13
Structural evidence for independent joining region gene in immunoglobulin heavy chains from anti-galactan myeloma proteins and its potential role in generating diversity in complementarity-determining regions. Proc Natl Acad Sci U S A (1979) 1.89
Organization of four mouse lambda light chain immunoglobulin genes. Proc Natl Acad Sci U S A (1981) 1.73
The diversity of the influenza-specific primary B-cell repertoire in BALB/c mice. J Exp Med (1978) 1.69
On a regulatory gene controlling the expression of the murine lambda1 light chain. J Exp Med (1978) 1.32
Comparison of mRNA precursors in plasmacytomas producing closely related kappa chains. Proc Natl Acad Sci U S A (1979) 1.26
cDNA sequence of a new chicken embryonic rho-globin. Proc Natl Acad Sci U S A (1981) 1.26
Expression of phosphorylcholine-specific B cells during murine development. J Exp Med (1977) 1.19
Change in quantity and size distribution of small circular DNAs during development of chicken bursa. Proc Natl Acad Sci U S A (1978) 1.11
Variable and constant regions are separated in the 10-kbase transcription unit coding for immunoglobulin kappa light chains. Proc Natl Acad Sci U S A (1978) 1.10
Sequence variation among heavy chains from inulin-binding myeloma proteins. Proc Natl Acad Sci U S A (1978) 1.06
Lambda2 light chains in normal mouse immunoglobulins. Proc Natl Acad Sci U S A (1978) 1.03
Characterization of a mouse DNA clone containing an immunoglobulin variable region gene. Nucleic Acids Res (1978) 0.99
Sequence variability of immunoglobulins considered from the standpoint of population genetics. Proc Natl Acad Sci U S A (1978) 0.94
Origin of transcription of a mouse immunoglobulin light chain gene. EMBO J (1982) 0.89
Cell-cycle-associated rearrangement of inverted repeat DNA sequences. Proc Natl Acad Sci U S A (1979) 0.86
Clustering and methylation of repeated DNA: persistence in avian development and evolution. Nucleic Acids Res (1981) 0.83
Organization of the sequences flanking immunoglobulin heavy chain genes and their role in class switching. Nucleic Acids Res (1980) 0.83
From the structure of antibodies to the diversification of the immune response. EMBO J (1985) 0.76
Roy Cameron lecture. Control of antibody formation: certain uncertainties. J Clin Pathol Suppl (R Coll Pathol) (1979) 0.75
Somatic generation of antibody diversity. Nature (1983) 28.06
RAG-1-deficient mice have no mature B and T lymphocytes. Cell (1992) 20.97
A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene. Cell (1983) 18.86
Sequences at the somatic recombination sites of immunoglobulin light-chain genes. Nature (1979) 11.83
Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes. Nature (1980) 10.19
B lineage--specific interactions of an immunoglobulin enhancer with cellular factors in vivo. Science (1985) 9.73
A complete immunoglobulin gene is created by somatic recombination. Cell (1978) 8.53
Subregion- and cell type-restricted gene knockout in mouse brain. Cell (1996) 8.02
Sequences of mouse immunoglobulin light chain genes before and after somatic changes. Cell (1978) 7.53
The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory. Cell (1996) 6.96
Sequence of a mouse germ-line gene for a variable region of an immunoglobulin light chain. Proc Natl Acad Sci U S A (1978) 6.80
Ordered rearrangement of immunoglobulin heavy chain variable region segments. EMBO J (1984) 6.67
Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice. Cell (1993) 5.99
Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions. Proc Natl Acad Sci U S A (1976) 5.81
BDNF regulates the maturation of inhibition and the critical period of plasticity in mouse visual cortex. Cell (1999) 5.63
Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase II mutant mice. Science (1992) 5.46
Organization, structure, and assembly of immunoglobulin heavy chain diversity DNA segments. J Exp Med (1982) 5.37
Domains and the hinge region of an immunoglobulin heavy chain are encoded in separate DNA segments. Nature (1979) 5.35
Evidence for a differential avidity model of T cell selection in the thymus. Cell (1994) 5.24
Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences. Nature (1984) 5.19
Impaired spatial learning in alpha-calcium-calmodulin kinase II mutant mice. Science (1992) 5.03
TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4-8+ T cells. Cell (1992) 4.76
Reduced stress defense in heme oxygenase 1-deficient cells. Proc Natl Acad Sci U S A (1997) 4.74
Junctional sequences of T cell receptor gamma delta genes: implications for gamma delta T cell lineages and for a novel intermediate of V-(D)-J joining. Cell (1989) 4.65
Heme oxygenase 1 is required for mammalian iron reutilization. Proc Natl Acad Sci U S A (1997) 4.63
Developmental regulation of T-cell receptor gene expression. Nature (1985) 4.53
Skeletal and CNS defects in Presenilin-1-deficient mice. Cell (1997) 4.50
Gamma/delta cells. Annu Rev Immunol (1993) 4.35
High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice. Cell (1994) 4.34
Identification of D segments of immunoglobulin heavy-chain genes and their rearrangement in T lymphocytes. Nature (1981) 4.26
Identification and nucleotide sequence of a diversity DNA segment (D) of immunoglobulin heavy-chain genes. Nature (1981) 4.19
T cell receptor delta gene mutant mice: independent generation of alpha beta T cells and programmed rearrangements of gamma delta TCR genes. Cell (1993) 4.18
Cell-type-specific contacts to immunoglobulin enhancers in nuclei. Nature (1985) 3.94
Structure and multiplicity of genes for the human immunoglobulin heavy chain variable region. Proc Natl Acad Sci U S A (1980) 3.82
Forebrain-specific calcineurin knockout selectively impairs bidirectional synaptic plasticity and working/episodic-like memory. Cell (2001) 3.55
Homing of a gamma delta thymocyte subset with homogeneous T-cell receptors to mucosal epithelia. Nature (1990) 3.55
Structure, organization, and somatic rearrangement of T cell gamma genes. Cell (1985) 3.49
Different roles of alpha beta and gamma delta T cells in immunity against an intracellular bacterial pathogen. Nature (1993) 3.47
A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes. Nature (1984) 3.46
Transcription of mouse kappa chain genes: implications for allelic exclusion. Proc Natl Acad Sci U S A (1980) 3.38
Activation of the c-myc gene by translocation: a model for translational control. Proc Natl Acad Sci U S A (1983) 3.36
Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice. Cell (1994) 3.35
Cloning of an immunoglobulin variable region gene from mouse embryo. Proc Natl Acad Sci U S A (1977) 3.21
Cell type-specific enhancer element associated with a mouse MHC gene, E beta. Nature (1984) 3.16
Complete primary structures of the E beta chain and gene of the mouse major histocompatibility complex. Proc Natl Acad Sci U S A (1983) 3.09
Preserved acute pain and reduced neuropathic pain in mice lacking PKCgamma. Science (1997) 2.98
Variable and constant parts of the immunoglobulin light chain gene of a mouse myeloma cell are 1250 nontranslated bases apart. Proc Natl Acad Sci U S A (1977) 2.93
Activation of a translocated human c-myc gene by an enhancer in the immunoglobulin heavy-chain locus. Nature (1984) 2.93
Diversity of murine gamma genes and expression in fetal and adult T lymphocytes. Nature (1986) 2.89
Intestinal intraepithelial lymphocytes are a distinct set of gamma delta T cells. Nature (1988) 2.89
The role of DNA rearrangement and alternative RNA processing in the expression of immunoglobulin delta genes. Cell (1981) 2.85
Exon shuffling generates an immunoglobulin heavy chain gene. Proc Natl Acad Sci U S A (1980) 2.80
Monoclonal antibodies specific to native murine T-cell receptor gamma delta: analysis of gamma delta T cells during thymic ontogeny and in peripheral lymphoid organs. Proc Natl Acad Sci U S A (1989) 2.79
Intracisternal A-particle genes as movable elements in the mouse genome. Proc Natl Acad Sci U S A (1983) 2.76
Impaired hippocampal representation of space in CA1-specific NMDAR1 knockout mice. Cell (1996) 2.62
DNA clones containing mouse immunoglobulin kappa chain genes isolated by in vitro packaging into phage lambda coats. Proc Natl Acad Sci U S A (1978) 2.60
Cortex-restricted disruption of NMDAR1 impairs neuronal patterns in the barrel cortex. Nature (2000) 2.60
Limited diversity of the rearranged T-cell gamma gene. Nature (1985) 2.58
Bcl-2 promotes regeneration of severed axons in mammalian CNS. Nature (1997) 2.57
Myelin basic protein-specific T helper 2 (Th2) cells cause experimental autoimmune encephalomyelitis in immunodeficient hosts rather than protect them from the disease. J Exp Med (1997) 2.51
Elimination of cocaine-induced hyperactivity and dopamine-mediated neurophysiological effects in dopamine D1 receptor mutant mice. Cell (1994) 2.46
Extrathymic origin of intestinal intraepithelial lymphocytes bearing T-cell antigen receptor gamma delta. Proc Natl Acad Sci U S A (1991) 2.46
Mutant immunoglobulin genes have repetitive DNA elements inserted into their intervening sequences. Proc Natl Acad Sci U S A (1982) 2.44
Nobel laureates' letter to President Bush. Washington Post (2001) 2.43
TAP1-dependent peptide translocation in vitro is ATP dependent and peptide selective. Cell (1993) 2.43
Electrophoretically homogeneous myeloma light chain mRNA and its translation in vitro. Biochem Biophys Res Commun (1973) 2.42
Altered peptidase and viral-specific T cell response in LMP2 mutant mice. Immunity (1994) 2.39
Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8- thymocyte differentiation. J Immunol (1994) 2.38
Unusual organization and diversity of T-cell receptor alpha-chain genes. Nature (1985) 2.36
Production of functional chimaeric mouse/human antibody. Nature (1985) 2.35
Recognition of the product of a novel MHC TL region gene (27b) by a mouse gamma delta T cell receptor. Cell (1990) 2.33
Somatic mutation creates diversity in the major group of mouse immunoglobulin kappa light chains. J Exp Med (1984) 2.33
Attachment of an anti-receptor antibody to non-target cells renders them susceptible to lysis by a clone of cytotoxic T lymphocytes. Proc Natl Acad Sci U S A (1984) 2.32
Fusarium solani cutinase is a lipolytic enzyme with a catalytic serine accessible to solvent. Nature (1992) 2.28
The reliability of alcohol abusers' self-reports of drinking and life events that occurred in the distant past. J Stud Alcohol (1988) 2.26
Localization of gamma/delta T cells to the intestinal epithelium is independent of normal microbial colonization. J Exp Med (1990) 2.23
Homeostatic regulation of intestinal epithelia by intraepithelial gamma delta T cells. Proc Natl Acad Sci U S A (1995) 2.21
Diversity of gamma delta T-cell receptors on murine intestinal intra-epithelial lymphocytes. Nature (1989) 2.21
Abnormal fear response and aggressive behavior in mutant mice deficient for alpha-calcium-calmodulin kinase II. Science (1994) 2.20
Reiteration frequency of immunoglobulin light chain genes: further evidence for somatic generation of antibody diversity. Proc Natl Acad Sci U S A (1976) 2.20
Immunoglobulin gene rearrangement in immature B cells. Science (1980) 2.14
Modified hippocampal long-term potentiation in PKC gamma-mutant mice. Cell (1993) 2.14
Restoration of early thymocyte differentiation in T-cell receptor beta-chain-deficient mutant mice by transmembrane signaling through CD3 epsilon. Proc Natl Acad Sci U S A (1993) 2.06
Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses. Cell (1994) 2.05
Functional immunoglobulin M production after transfection of cloned immunoglobulin heavy and light chain genes into lymphoid cells. Proc Natl Acad Sci U S A (1983) 2.03
Evidence for somatic generation of antibody diversity. Proc Natl Acad Sci U S A (1974) 2.03
Peptide contributes to the specificity of positive selection of CD8+ T cells in the thymus. Cell (1993) 1.96
Diversity and joining segments of mouse immunoglobulin heavy chain genes are closely linked and in the same orientation: implications for the joining mechanism. Proc Natl Acad Sci U S A (1983) 1.93
Cytokine imbalance and autoantibody production in T cell receptor-alpha mutant mice with inflammatory bowel disease. J Exp Med (1996) 1.91
Different gamma delta T-cell receptors are expressed on thymocytes at different stages of development. Proc Natl Acad Sci U S A (1989) 1.91
PKC gamma mutant mice exhibit mild deficits in spatial and contextual learning. Cell (1993) 1.84
Recognition of a self major histocompatibility complex TL region product by gamma delta T-cell receptors. Proc Natl Acad Sci U S A (1989) 1.84
Brain-derived neurotrophic factor overexpression induces precocious critical period in mouse visual cortex. J Neurosci (1999) 1.82
Whisker-related neuronal patterns fail to develop in the trigeminal brainstem nuclei of NMDAR1 knockout mice. Cell (1994) 1.82
Secondary, tertiary, and quaternary structure of T-cell-specific immunoglobulin-like polypeptide chains. Proc Natl Acad Sci U S A (1986) 1.81