Published in Lancet on March 20, 1971
Altered calcium metabolism in epileptic children on anticonvulsants. Br Med J (1971) 2.86
Folate deficiency after anticonvulsant drugs: an effect of hepatic enzyme induction? Br Med J (1972) 1.95
Osteomalacia after prolonged glutethimide administration. Br Med J (1973) 1.67
Identification of an inducible form of cytochrome P-450 in human liver. Proc Natl Acad Sci U S A (1985) 1.62
Assessment of the drug metabolism capacity of the liver. Br J Clin Pharmacol (1982) 1.51
A comparative study of the relative enzyme inducing properties of anticonvulsant drugs in epileptic patients. Br J Clin Pharmacol (1984) 1.24
Effect of phenobarbitone on hepatic drug-metabolizing enzymes and urinary D-glucaric acid excretion in man. Br J Clin Pharmacol (1975) 1.23
Early identification of alcohol abuse: 2: Clinical and laboratory indicators. Can Med Assoc J (1981) 1.21
Effect of low-dose phenobarbitone on five indirect indices of hepatic microsomal enzyme induction and plasma lipoproteins in normal subjects. Br J Clin Pharmacol (1981) 1.05
The features of hepatic enzyme induction with glutethimide in man. Br J Clin Pharmacol (1978) 1.02
Anticonvulsant osteomalacia. Br Med J (1971) 0.95
Hepatic drug-oxidizing enzyme systems and urinary D-glucaric acid excretion in patients with congestive heart failure. Br J Clin Pharmacol (1975) 0.92
Serum bilirubin and hepatic enzyme induction. Br Med J (1979) 0.92
Pheneturide, a more potent liver enzyme inducer in man than phenobarbitone? Br J Pharmacol (1973) 0.90
Urinary D-glucaric acid excretion in the Seveso area, polluted by tetrachloro-dibenzo-p-dioxin (TCDD): five years of experience. Environ Health Perspect (1985) 0.85
Guide to drug porphyrogenicity prediction and drug prescription in the acute porphyrias. Br J Clin Pharmacol (2007) 0.85
Overnight urine specimens for the determination of D-glucaric acid excretion in man. Br J Clin Pharmacol (1979) 0.79
Exposure to toluene increases the urinary excretion of D-glucaric acid. Br J Ind Med (1990) 0.77
Effect of ticlopidine treatment on liver metabolizing enzymes in man. Br J Clin Pharmacol (1980) 0.75
Urinary D-glucaric acid excretion and plasma antipyrine kinetics during enzyme induction. Br J Clin Pharmacol (1974) 0.75
Ethosuximide: liver enzyme induction and D-glucaric acid excretion. Br J Clin Pharmacol (1974) 0.75
Individual variation in daily dosage requirements for phenytoin sodium in patients with epilepsy. Br J Clin Pharmacol (1978) 0.75
The clinical consequences of chronic hepatic enzyme induction by anticonvulsant drugs. Br J Clin Pharmacol (1974) 0.75
The influence of elevated plasma hydrocortisone concentrations on antipyrine metabolism in man. Br J Clin Pharmacol (1974) 0.75
Teratogenic effects of anticonvulsants. Br Med J (1971) 0.75
Letter: Vitamin D deficiency in rheumatoid arthritis. Br Med J (1975) 0.75
Drug metabolism and hepatotoxicity. Gut (1991) 0.75
Urinary D-glucaric acid and oral contraceptives. Br J Clin Pharmacol (1978) 0.75
The effect of fluphenazine decanoate (modecate) on hepatic microsomal enzyme activity in man. Br J Clin Pharmacol (1974) 0.75
Urinary glucaric acid excretion in rheumatoid arthritis: influence of disease activity and disease modifying drugs. Ann Rheum Dis (1996) 0.75
Steady-state plasma nortriptyline concentrations in epileptic patients. Br J Clin Pharmacol (1975) 0.75
Enhanced drug metabolism and renal dysfunction. Br J Clin Pharmacol (1981) 0.75
A simple technique for the rapid estimation of ethosuximide by gas liquid chromatography. Br J Clin Pharmacol (1974) 0.75
Transection of the oesophagus for bleeding oesophageal varices. Br J Surg (1973) 26.26
Early indicators of prognosis in fulminant hepatic failure. Gastroenterology (1989) 7.43
Cost analysis of early discharge after hip fracture. BMJ (1993) 6.64
Deaths from low dose paracetamol poisoning. BMJ (1998) 6.63
Anti-tuberculous therapy and acute liver failure. Lancet (1995) 6.27
Causes and outcomes of the acute chest syndrome in sickle cell disease. National Acute Chest Syndrome Study Group. N Engl J Med (2000) 6.07
Global trends in resistance to antituberculosis drugs. World Health Organization-International Union against Tuberculosis and Lung Disease Working Group on Anti-Tuberculosis Drug Resistance Surveillance. N Engl J Med (2001) 6.05
The effect of group psychosocial support on survival in metastatic breast cancer. N Engl J Med (2001) 5.95
Prospective screening of dyspeptic patients by Helicobacter pylori serology. Lancet (1995) 5.02
Acute liver failure: redefining the syndromes. Lancet (1993) 4.99
Vulnerability genes or plasticity genes? Mol Psychiatry (2009) 4.96
Hepatitis C virus antibodies in chronic active hepatitis: pathogenetic factor or false-positive result? Lancet (1990) 4.57
Liver transplantation in man. I. Observations on technique and organization in five cases. Br Med J (1968) 4.38
Improved outcome of paracetamol-induced fulminant hepatic failure by late administration of acetylcysteine. Lancet (1990) 4.27
Long-term outcome of hepatitis C infection after liver transplantation. N Engl J Med (1996) 4.10
Daily variation of particulate air pollution and poor cardiac autonomic control in the elderly. Environ Health Perspect (1999) 4.07
Ultrasound scanning in the detection of hepatic fibrosis and steatosis. Br Med J (Clin Res Ed) (1986) 3.94
Cell-mediated immunity to a human liver-specific antigen in patients with active chronic hepatitis and primary biliary cirrhosis. Lancet (1972) 3.90
The role of virus-specific CD8(+) cells in liver damage and viral control during persistent hepatitis B virus infection. J Exp Med (2000) 3.78
A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. Nat Genet (2000) 3.63
Inadequate antibody response to hBAg or suppressor T-cell defect in development of active chronic hepatitis. Lancet (1974) 3.61
Dissociable deficits in the decision-making cognition of chronic amphetamine abusers, opiate abusers, patients with focal damage to prefrontal cortex, and tryptophan-depleted normal volunteers: evidence for monoaminergic mechanisms. Neuropsychopharmacology (1999) 3.60
Salivary antibodies to Helicobacter pylori: screening dyspeptic patients before endoscopy. Lancet (1994) 3.45
Screening for type 2 diabetes: literature review and economic modelling. Health Technol Assess (2007) 3.40
Structured patient education: the diabetes X-PERT Programme makes a difference. Diabet Med (2006) 3.36
Detection of antibodies directed against a liver-specific membrane lipoprotein in patients with acute and chronic active hepatitis. N Engl J Med (1978) 3.28
Plasma endothelin immunoreactivity in liver disease and the hepatorenal syndrome. N Engl J Med (1992) 3.24
NHLBI Family Heart Study: objectives and design. Am J Epidemiol (1996) 3.21
Lymphocyte cytotoxicity to isolated hepatocytes in chronic active hepatitis. Nature (1974) 3.17
Purification and characterization of human liver-specific membrane lipoprotein (LSP). Clin Exp Immunol (1977) 3.13
Improved survival after orthotopic liver grafting. Br Med J (Clin Res Ed) (1981) 3.09
Specificity of T lymphocyte cytotoxicity to autologous hepatocytes in chronic hepatitis B virus infection: evidence that T cells are directed against HBV core antigen expressed on hepatocytes. J Immunol (1982) 3.09
Mutations that alter the ability of the Escherichia coli cyclic AMP receptor protein to activate transcription. Nucleic Acids Res (1990) 3.08
Adrenergic innervation of sphincteric and nonsphincteric smooth muscle in the rat intestine. J Histochem Cytochem (1971) 3.07
Presence of a newly described human DNA virus (TTV) in patients with liver disease. Lancet (1998) 3.06
Liver transplantation for malignant disease. Results in 93 consecutive patients. Ann Surg (1988) 3.04
Controlled trial of prednisone and azathioprine in active chronic hepatitis. Lancet (1973) 2.98
Use of partial cardiopulmonary bypass during the anhepatic phase of orthotopic liver grafting. Lancet (1979) 2.98
Intravenous acetylcysteine in paracetamol induced fulminant hepatic failure: a prospective controlled trial. BMJ (1991) 2.94
More donor organs for transplantation. Elective ventilation proposals. J R Coll Physicians Lond (1993) 2.91
Multisystem involvement in chronic liver disease. Studies on the incidence and pathogenesis. Am J Med (1973) 2.88
Altered calcium metabolism in epileptic children on anticonvulsants. Br Med J (1971) 2.86
The arthropathy of idiopathic haemochromatosis. Q J Med (1968) 2.85
Hepatitis B virus infection in medical and health care personnel. Br Med J (Clin Res Ed) (1982) 2.85
Seasonality of tuberculosis: the reverse of other respiratory diseases in the UK. Thorax (1996) 2.82
Liver transplantation after paracetamol overdose. BMJ (1991) 2.81
New hepatitis C virus (HCV) genotyping system that allows for identification of HCV genotypes 1a, 1b, 2a, 2b, 3a, 3b, 4, 5a, and 6a. J Clin Microbiol (1997) 2.78
Comparison of liver histology with ultrasonography in assessing diffuse parenchymal liver disease. Clin Radiol (1991) 2.76
Liver disease and bile duct abnormalities in adults with cystic fibrosis. Lancet (1989) 2.76
Vitamin D supplements in pregnant Asian women: effects on calcium status and fetal growth. Br Med J (1980) 2.75
Liver in Felty's syndrome. Br Med J (1970) 2.75
Hepatic damage and death from overdose of paracetamol. Lancet (1973) 2.70
Overexpressing endothelial cell protein C receptor alters the hemostatic balance and protects mice from endotoxin. J Thromb Haemost (2005) 2.70
Extrahepatic biliary atresia versus neonatal hepatitis. Review of 137 prospectively investigated infants. Arch Dis Child (1976) 2.67
Cyclosporin A in cadaveric organ transplantation. Br Med J (Clin Res Ed) (1981) 2.67
Improvement by acetylcysteine of hemodynamics and oxygen transport in fulminant hepatic failure. N Engl J Med (1991) 2.65
Direct ex vivo analysis of hepatitis B virus-specific CD8(+) T cells associated with the control of infection. Gastroenterology (1999) 2.62
Controlled trials of charcoal hemoperfusion and prognostic factors in fulminant hepatic failure. Gastroenterology (1988) 2.60
Treatment of hepatic encephalopathy. N Engl J Med (1997) 2.60
Liver transplantation. Curr Probl Surg (1979) 2.57
Treatment of fulminant hepatic failure by polyacrylonitrile-membrane haemodialysis. Lancet (1977) 2.53
Acute liver failure secondary to hepatic infiltration: a single centre experience of 18 cases. Gut (1998) 2.51
Orthotopic liver transplantation: the first 60 patients. Br Med J (1977) 2.50
A habitable fluvio-lacustrine environment at Yellowknife Bay, Gale crater, Mars. Science (2013) 2.50
A survey of prelicensure pain curricula in health science faculties in Canadian universities. Pain Res Manag (2009) 2.49
The systemic inflammatory response syndrome in acute liver failure. Hepatology (2000) 2.47
Decline in admission rates for acute appendicitis in England. Br J Surg (2003) 2.47
Incubation phase of acute hepatitis B in man: dynamic of cellular immune mechanisms. Hepatology (2000) 2.45
Down-regulation of the novel gene melastatin correlates with potential for melanoma metastasis. Cancer Res (1998) 2.43
Attentional bias in anxiety and depression: the role of awareness. Br J Clin Psychol (1995) 2.43
Developing and deploying a patient safety program in a large health care delivery system: you can't fix what you don't know about. Jt Comm J Qual Improv (2001) 2.42
Antibodies to the surface of halothane-altered rabbit hepatocytes in patients with severe halothane-associated hepatitis. N Engl J Med (1980) 2.41
Azathioprine for long-term maintenance of remission in autoimmune hepatitis. N Engl J Med (1995) 2.41
1 -Antitrypsin deficiency and neonatal hepatitis. Br Med J (1972) 2.40
General practice orthopaedic outpatient referrals in North Staffordshire. Br Med J (Clin Res Ed) (1983) 2.38
Relation of renal impairment and haemorrhagic diathesis to endotoxaemia in fulminant hepatic failure. Lancet (1974) 2.37
Draft guidance for industry extended-release solid oral dosage forms. Development, evaluation and application of in vitro-in vivo correlations. Adv Exp Med Biol (1997) 2.35
Cyclosporin A treatment in primary biliary cirrhosis: results of a long-term placebo controlled trial. Gastroenterology (1993) 2.32
Long-term anticonvulsant therapy worsens outcome in paracetamol-induced fulminant hepatic failure. Hum Exp Toxicol (1992) 2.31
Influence of delta infection on severity of hepatitis B. Lancet (1982) 2.31
Increased long-term survival in variceal haemorrhage using injection sclerotherapy. Results of a controlled trial. Lancet (1982) 2.30
The coming-out process and its adaptational and health-related associations among gay, lesbian, and bisexual youths: stipulation and exploration of a model. Am J Community Psychol (2001) 2.30
Treatment of secondary hepatic tumours by ligation of hepatic artery and infusion of cytotoxic drugs. Lancet (1970) 2.25
Cytomegalovirus hepatitis in the adult. Lancet (1967) 2.20
Serial prothrombin time as prognostic indicator in paracetamol induced fulminant hepatic failure. BMJ (1990) 2.18
Detection of hepatitis-B antigen by radioimmunoassay in chronic liver disease and hepatocellular carcinoma in Great Britain. Lancet (1973) 2.17
Assessment of non-mydriatic fundus photography in detection of diabetic retinopathy. Br Med J (Clin Res Ed) (1986) 2.16
Fasting proinsulin concentrations predict the development of type 2 diabetes. Diabetes Care (1999) 2.16
Portal hypertension in idiopathic tropical splenomegaly. Lancet (1966) 2.16
Treatment of multiple-hormone-producing malignant islet-cell tumour with streptozotocin. Lancet (1968) 2.14
Measurement and characterization of postischemic free radical generation in the isolated perfused heart. J Biol Chem (1989) 2.14
Antibiotic resistant tuberculosis in the United Kingdom: 1993-1999. Thorax (2002) 2.12
A 7-year experience of severe acetaminophen-induced hepatotoxicity (1987-1993). Gastroenterology (1995) 2.11
H2-receptor antagonists and antacids in the prevention of acute gastrointestinal haemorrhage in fulminant hepatic failure. Two controlled trials. Lancet (1977) 2.10
CNS aquaporin-4 autoimmunity in children. Neurology (2008) 2.10