Published in N Engl J Med on March 30, 1972
C2 deficiency. Development of lupus erythematosus. J Clin Invest (1973) 2.52
Complete absence of the third component of complement in man. J Clin Invest (1975) 1.75
Hereditary deficiency of the sixth component of complement in man. I. Immunochemical, biologic, and family studies. J Clin Invest (1974) 1.65
Plasma C3 and C4 concentrations in management of glomerulonephritis. Br Med J (1973) 1.53
The association of respiratory infection, recurrent hematuria, and focal glomerulonephritis with activation of the complement system in the cold. J Clin Invest (1973) 1.13
Familial C1q deficiency associated with renal and cutaneous disease. Clin Exp Immunol (1981) 0.97
Early Components of the Complement Classical Activation Pathway in Human Systemic Autoimmune Diseases. Front Immunol (2016) 0.88
Clinical and immunological studies in a case of selective complete C1q deficiency. Clin Exp Immunol (1979) 0.88
Spectrum and management of complement immunodeficiencies (excluding hereditary angioedema) across Europe. J Clin Immunol (2015) 0.85
Hereditary angio-oedema with mesangiocapillary glomerulonephritis. Postgrad Med J (1977) 0.84
The autosomal recessive mode of inheritance of C1r deficiency in a large Puerto Rican family. Clin Exp Immunol (1974) 0.81
C3 metabolism in a patient with deficiency of the second component of complement (C2) and discoid lupus erythematosus. Clin Exp Immunol (1976) 0.81
Heat production in different populations of human blood cells exposed to immune complexes in vitro: the importance of the Fc parts of immunoglobulins and the influence of active complement. Immunology (1982) 0.78
Familial cutaneous lupus erythematosus (CLE) in the German shorthaired pointer maps to CFA18, a canine orthologue to human CLE. Immunogenetics (2010) 0.77
Genetics of the complement system. J Med Genet (1975) 0.77
The immunological basis of glomerulonephritis. Proc R Soc Med (1974) 0.75
In vitro bactericidal capacity of human polymorphonuclear leukocytes: diminished activity in chronic granulomatous disease of childhood. J Clin Invest (1967) 10.26
Studies of the metabolic activity of leukocytes from patients with a genetic abnormality of phagocytic function. J Clin Invest (1967) 9.01
Evolutionary conservation of surface molecules that distinguish T lymphocyte helper/inducer and cytotoxic/suppressor subpopulations in mouse and man. J Exp Med (1981) 6.82
Suppressor cell activity after concanavalin A treatment of lymphocytes from normal donors. J Exp Med (1976) 5.50
Acute poststreptococcal glomerulonephritis: immune deposit disease. J Clin Invest (1966) 4.64
Immunological reconstitution of sex-linked lymphopenic immunological deficiency. Lancet (1968) 4.41
Thymus-dependent membrane antigens in man: inhibition of cell-mediated lympholysis by monoclonal antibodies to TH2 antigen. Proc Natl Acad Sci U S A (1981) 4.38
The functions of the thymus system and the bursa system in the chicken. J Exp Med (1966) 4.07
Fatal granulomatous disease of childhood. An inborn abnormality of phagocytic function. Lancet (1966) 3.97
The IgA system. I. Studies of the transport and immunochemistry of IgA in the saliva. J Exp Med (1966) 3.97
Primary immunodeficiencies. Report of a World Health Organization Committee. Pediatrics (1971) 3.69
Wiskott-Aldrich syndrome. An immunologic deficiency disease involving the afferent limb of immunity. Am J Med (1968) 3.54
Protection of phagocytized bacteria from the killing action of antibiotics. Nature (1966) 3.12
Identification of a p69,71 complex expressed on human T cells sharing determinants with B-type chronic lymphatic leukemic cells. J Exp Med (1980) 2.89
Complement activity and inflammatory neutrophil exudation in man. Studies in patients with glomerulonephritis, essential hypocomplementemia and agammaglobulinemia. Int Arch Allergy Appl Immunol (1967) 2.64
The cellular immune defect in chronic mucocutaneous candidiasis. Lancet (1969) 2.53
C2 deficiency. Development of lupus erythematosus. J Clin Invest (1973) 2.52
A newly defined X-linked trait in man with demonstration of the Lyon effect in carrier females. Lancet (1967) 2.47
Influence of diet on survival of mice. Proc Natl Acad Sci U S A (1976) 2.45
An NK1.1+ CD4+8- single-positive thymocyte subpopulation that expresses a highly skewed T-cell antigen receptor V beta family. Proc Natl Acad Sci U S A (1992) 2.43
Deficient immunologic functions of NZB mice. Proc Soc Exp Biol Med (1968) 2.41
The complement profile in acute glomerulonephritis systemic lupus erythematosus and hypocomplementemic chronic glomerulonephritis. Contrasts and experimental correlations. Int Arch Allergy Appl Immunol (1968) 2.38
Effects of protein insufficiency on immune responsiveness. Am J Clin Nutr (1974) 2.37
Localization of immunological complexes fixing beta1C (C3) in germinal centers of lymph nodes. J Exp Med (1969) 2.36
Chemical suppression of adaptive immunity. Adv Immunol (1967) 2.35
Growth of a pure population of mouse mast cells in vitro with conditioned medium derived from concanavalin A-stimulated splenocytes. Proc Natl Acad Sci U S A (1981) 2.33
NK1.1+ CD4+ CD8- thymocytes with specific lymphokine secretion. Eur J Immunol (1993) 2.32
Effect of antibiotics on the bactericidal activity of human leukocytes. J Lab Clin Med (1968) 2.31
Occurrence of malignancy in immunodeficiency diseases. A literature review. Cancer (1971) 2.31
T-cell depletion of HLA-identical transplants in leukemia. Blood (1991) 2.25
Monoclonal antibody analysis of human T lymphocyte subpopulations exhibiting autologous mixed lymphocyte reaction. Proc Natl Acad Sci U S A (1981) 2.16
Suppression of B-cell differentiation by leukocytes from hypogammaglobulinemic patients. J Clin Invest (1976) 2.15
A mammalian equivalent of the avian bursa of Fabricius. Lancet (1966) 2.11
Improved tests for the evaluation of neutrophil function in human disease. J Lab Clin Med (1968) 2.11
Development and function of the immunoglobulin producing system. I. Effect of bursectomy at different stages of development on germinal centers, plasma cells, immunoglobulins and antibody production. Int Arch Allergy Appl Immunol (1969) 2.06
Kaposi's sarcoma: a review and recent developments. CA Cancer J Clin (1981) 2.05
Ubiquitin-dependent degradation of IkappaBalpha is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1. Proc Natl Acad Sci U S A (1999) 2.04
Development of "autoimmune processes" in rabbits after neonatal removal of central lymphoid tissue. Lancet (1965) 2.04
Influence of the human T-lymphotropic virus/lymphadenopathy-associated virus on functions of human lymphocytes: evidence for immunosuppressive effects and polyclonal B-cell activation by banded viral preparations. Proc Natl Acad Sci U S A (1985) 2.04
Prevention of type I diabetes in nonobese diabetic mice by allogenic bone marrow transplantation. Proc Natl Acad Sci U S A (1985) 2.03
Phytohaemagglutinin unresponsiveness of lymphocytes from babies with congenital rubella. Nature (1967) 1.99
Mechanism of action of migration inhibitory factor (MIF). I. Evidence for a receptor for MIF present on the peritoneal macrophage but not on the alveolar macrophage. J Exp Med (1972) 1.99
Risk factors for chronic graft-versus-host disease after HLA-identical sibling bone marrow transplantation. Blood (1990) 1.98
Rationale for bone marrow transplantation in the treatment of autoimmune diseases. Proc Natl Acad Sci U S A (1985) 1.97
The nephrotic syndrome of childhood: immunologic, clinical, and pathologic correlations. J Clin Invest (1966) 1.96
Humoral and cell-mediated immune responses in fully allogeneic bone marrow chimera in mice. J Exp Med (1980) 1.94
Chronic glomerulonephritis associated with low serum complement activity (chronic hypocomplementemic glomerulonephritis). Medicine (Baltimore) (1970) 1.94
Glomerular localization and transport of aggregated proteins in mice. Lab Invest (1967) 1.94
Passive hemolysis by serum and cobra venom factor: a new mechanism inducing membrane damage by complement. Proc Natl Acad Sci U S A (1969) 1.92
Phorbol myristate acetate: a mitogen selective for a T-lymphocyte subpopulation. J Exp Med (1977) 1.91
Rosette-formation with mouse erythrocytes. II. A marker for human B and non-T lymphocytes. Clin Exp Immunol (1976) 1.87
A proposed classification of primary immunologic deficiencies. Am J Med (1968) 1.83
Association of renal allograft rejection with virus infections. Am J Med (1974) 1.83
Decreased properdin activity in acute glomerulonephritis. Int Arch Allergy Appl Immunol (1969) 1.83
Abnormalities of in vitro lymphocyte responses during rubella virus infections. J Exp Med (1968) 1.82
Pneumocystis carinii infection. Medicine (Baltimore) (1973) 1.79
Hypothalamic-pituitary-adrenal axis suppression associated with the use of inhaled fluticasone propionate. J Allergy Clin Immunol (1998) 1.77
Subpopulations of human T lymphocytes. II. Effect of thymopoietin, corticosteroids, and irradiation. Cell Immunol (1977) 1.76
Role of the thymus and other central lymphoid tissues in immunological disease. Annu Rev Med (1967) 1.76
Hereditary C2 deficiency: Genetic studies and association with the HL-A system. J Exp Med (1975) 1.75
Complete absence of the third component of complement in man. J Clin Invest (1975) 1.75
Absence of enhancing antibody in cell mediated immunity to tumour heterografts in protein deficient rats. Nature (1971) 1.74
N.B.T. test stimulated. Lancet (1970) 1.73
B and T lymphocytes in primary immunodeficiency disease in man. J Clin Invest (1973) 1.72
Ontogeny of lymphocyte subpopulations in human fetal liver. Proc Natl Acad Sci U S A (1976) 1.71
Biosynthesis and secretion of immunoglobulins by peripheral-blood lymphocytes in severe hypogammaglobulinaemia. Lancet (1972) 1.71
Transplantation for acute leukaemia with HLA-A and B nonidentical parental marrow cells fractionated with soybean agglutinin and sheep red blood cells. Lancet (1981) 1.70
Lymphoid tissue abnormalities associated with ataxia-telangiectasia. Am J Med (1966) 1.69
Subpopulations of human T lymphocytes. I. Studies in immunodeficient patients. Clin Exp Immunol (1977) 1.69
Autoimmune phenomena and renal disease in mice. Role of thymectomy, aging, and involution of immunologic capacity. Lab Invest (1970) 1.69
Role of helper, suppressor and B-cell defects in the pathogenesis of the hypogammaglobulinemias. N Engl J Med (1978) 1.64
Complement and complement-like activity in lower vertebrates and invertebrates. J Exp Med (1970) 1.61
Identification of mutations in the c-mpl gene in congenital amegakaryocytic thrombocytopenia. Proc Natl Acad Sci U S A (1999) 1.61
Three distinct stages of B-cell defects in common varied immunodeficiency. Proc Natl Acad Sci U S A (1982) 1.60
Lymphocyte studies in congenital thymic dysplasia: The one-way stimulation test. J Pediatr (1968) 1.59
Impairment of cell-mediated immunity functions by dietary zinc deficiency in mice. Proc Natl Acad Sci U S A (1979) 1.59
Fatal (chronic) granulomatous disease of childhood: a hereditary defect of leukocyte function. Semin Hematol (1968) 1.58
Treatment of lymphopenic hypogammaglobulinemia and bone-marrow aplasia by transplantation of allogeneic marrow. Crucial role of histocompatiility matching. N Engl J Med (1969) 1.58
Age, thymic involution, and circulating thymic hormone activity. J Clin Endocrinol Metab (1978) 1.58
Dyschondrosteosis. The most common cause of Madelung's deformity. J Pediatr (1966) 1.57
Complement-dependent biological functions in complement deficiency in man. Lancet (1966) 1.56
Thymus: a direct target tissue in graft-versus-host reaction after allogeneic bone marrow transplantation that results in abrogation of induction of self-tolerance. Proc Natl Acad Sci U S A (1990) 1.56
Complement inactivation by serum from patients with acute and hypocomplementemic chronic glomerulonephritis. J Lab Clin Med (1968) 1.54
Pathogenesis of avian lymphoid leukosis. I. Histogenesis. J Natl Cancer Inst (1968) 1.54
Stimulatory and inhibitory influences of human immunodeficiency virus on normal B lymphocytes. Proc Natl Acad Sci U S A (1986) 1.54
Ontogeny of circulating immunoglobulin in normal, bursectomized and irradiated chickens. J Immunol (1969) 1.54
A model for colostral IgA. Proc Natl Acad Sci U S A (1966) 1.53
C1r deficiency: an inborn error associated with cutaneous and renal disease. J Clin Invest (1972) 1.52
Influence of dietary restriction on immunologic function and renal disease in (NZB x NZW) F1 mice. Proc Natl Acad Sci U S A (1978) 1.52
Suppression of immunoglobulin synthesis and secretion by peripheral blood lymphocytes from normal donors. Proc Natl Acad Sci U S A (1977) 1.50