M G Sarngadharan

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Detection, isolation, and continuous production of cytopathic retroviruses (HTLV-III) from patients with AIDS and pre-AIDS. Science 1984 33.32
2 Antibodies reactive with human T-lymphotropic retroviruses (HTLV-III) in the serum of patients with AIDS. Science 1984 11.30
3 Characterization of highly immunogenic p66/p51 as the reverse transcriptase of HTLV-III/LAV. Science 1986 6.53
4 Characterization of gp41 as the transmembrane protein coded by the HTLV-III/LAV envelope gene. Science 1985 6.48
5 Serological analysis of a subgroup of human T-lymphotropic retroviruses (HTLV-III) associated with AIDS. Science 1984 5.43
6 A new subtype of human T-cell leukemia virus (HTLV-II) associated with a T-cell variant of hairy cell leukemia. Science 1982 5.30
7 Human immunodeficiency virus neutralizing antibodies recognize several conserved domains on the envelope glycoproteins. J Virol 1987 5.03
8 Determinants of retrovirus (HTLV-III) antibody and immunodeficiency conditions in homosexual men. Lancet 1984 4.68
9 Seroepidemiology of HTLV-III antibody in Danish homosexual men: prevalence, transmission, and disease outcome. Br Med J (Clin Res Ed) 1984 4.39
10 Screening test for HTLV-III (AIDS agent) antibodies. Specificity, sensitivity, and applications. JAMA 1985 4.26
11 Biochemical and immunological analysis of human immunodeficiency virus gag gene products p17 and p24. J Virol 1988 4.06
12 Seroepidemiological studies of human T-lymphotropic retrovirus type III in acquired immunodeficiency syndrome. Lancet 1984 3.77
13 Natural antibodies to the structural core protein (p24) of the human T-cell leukemia (lymphoma) retrovirus found in sera of leukemia patients in Japan. Proc Natl Acad Sci U S A 1982 3.75
14 HTLV-III in saliva of people with AIDS-related complex and healthy homosexual men at risk for AIDS. Science 1984 3.50
15 HTLV-III in cells cultured from semen of two patients with AIDS. Science 1984 3.47
16 Immunological and chemical analysis of P6, the carboxyl-terminal fragment of HIV P15. AIDS Res Hum Retroviruses 1987 3.03
17 Antibodies to HTLV-III in Swiss patients with AIDS and pre-AIDS and in groups at risk for AIDS. N Engl J Med 1985 2.95
18 The virus of Japanese adult T-cell leukaemia is a member of the human T-cell leukaemia virus group. Nature 1982 2.75
19 Immunological properties of a type C retrovirus isolated from cultured human T-lymphoma cells and comparison to other mammalian retroviruses. J Virol 1981 2.72
20 HTLV-III in symptom-free seronegative persons. Lancet 1984 2.71
21 Primary structure analysis of the major internal protein p24 of human type C T-cell leukemia virus. Proc Natl Acad Sci U S A 1982 2.57
22 Detection of human anti-HTLV-III antibodies by indirect immunofluorescence using fixed cells. Transfusion 1985 2.45
23 Primary human T-lymphotropic virus type III infection. Ann Intern Med 1985 2.40
24 Epidemiology of human T-cell leukemia/lymphoma virus. J Infect Dis 1983 2.26
25 Isolation of infectious human T-cell leukemia/lymphotropic virus type III (HTLV-III) from patients with acquired immunodeficiency syndrome (AIDS) or AIDS-related complex (ARC) and from healthy carriers: a study of risk groups and tissue sources. Proc Natl Acad Sci U S A 1985 2.26
26 Reverse transcriptase activity of human acute leukaemic cells: purification of the enzyme, response to AMV 70S RNA, and characterization of the DNA product. Nat New Biol 1972 2.25
27 Myristoylation of gag proteins of HIV-1 plays an important role in virus assembly. AIDS Res Hum Retroviruses 1990 2.15
28 Monoclonal antibodies specific for p24, the major core protein of human T-cell leukemia virus type III. Proc Natl Acad Sci U S A 1985 2.00
29 Risk of nosocomial infection with human T-cell lymphotropic virus III (HTLV-III). N Engl J Med 1985 1.99
30 Long-term inhibition of human T-lymphotropic virus type III/lymphadenopathy-associated virus (human immunodeficiency virus) DNA synthesis and RNA expression in T cells protected by 2',3'-dideoxynucleosides in vitro. Proc Natl Acad Sci U S A 1987 1.96
31 Human immunodeficiency virus reverse transcriptase. General properties and its interactions with nucleoside triphosphate analogs. J Biol Chem 1987 1.94
32 Human T-cell lymphotropic virus type III infection in a cohort of homosexual men in New York City. JAMA 1986 1.90
33 Seroepidemiology of human T-lymphotropic virus type III among homosexual men with the acquired immunodeficiency syndrome or generalized lymphadenopathy and among asymptomatic controls in Boston. Ann Intern Med 1985 1.89
34 Spectrum of human T-cell lymphotropic virus type III infection in children. Recognition of symptomatic, asymptomatic, and seronegative patients. JAMA 1986 1.87
35 Identification of a major growth factor for AIDS-Kaposi's sarcoma cells as oncostatin M. Science 1992 1.85
36 Antibodies in human sera reactive against an internal structural protein of human T-cell lymphoma virus. Nature 1981 1.79
37 Frequent transmission of HTLV-III among spouses of patients with AIDS-related complex and AIDS. JAMA 1985 1.76
38 Immunological properties of the Gag protein p24 of the acquired immunodeficiency syndrome retrovirus (human T-cell leukemia virus type III). Proc Natl Acad Sci U S A 1985 1.67
39 Heterosexually acquired HTLV-III/LAV disease (AIDS-related complex and AIDS). Epidemiologic evidence for female-to-male transmission. JAMA 1985 1.65
40 Role of oligosaccharides in the processing and maturation of envelope glycoproteins of human immunodeficiency virus type 1. Proc Natl Acad Sci U S A 1989 1.57
41 Development and early natural history of HTLV-III antibodies in persons with hemophilia. JAMA 1985 1.50
42 Complete amino acid sequence of human T-cell leukemia virus structural protein p15. FEBS Lett 1983 1.48
43 Processing of the structural proteins of human immunodeficiency virus type 1 in the presence of monensin and cerulenin. Proc Natl Acad Sci U S A 1988 1.38
44 Factors determining the activity of 2',3'-dideoxynucleosides in suppressing human immunodeficiency virus in vitro. Mol Pharmacol 1988 1.38
45 Characterization of the secreted, native gp120 and gp160 of the human immunodeficiency virus type 1. AIDS Res Hum Retroviruses 1990 1.30
46 Antibodies against three purified proteins of the human type C retrovirus, human T-cell leukemia-lymphoma virus, in adult T-cell leukemia-lymphoma patients and healthy Blacks from the Caribbean. Cancer Res 1983 1.30
47 Brefeldin A inhibits the processing and secretion of envelope glycoproteins of human immunodeficiency virus type 1. AIDS Res Hum Retroviruses 1991 1.27
48 An HTLV-III peptide produced by recombinant DNA is immunoreactive with sera from patients with AIDS. Nature 1985 1.26
49 Association of the human type C retrovirus with a subset of adult T-cell cancers. Cancer Res 1983 1.25
50 HTLV-I--associated B-cell CLL: indirect role for retrovirus in leukemogenesis. Science 1987 1.25
51 Antigens on HTLV-infected cells recognized by leukemia and AIDS sera are related to HTLV viral glycoprotein. Science 1984 1.21
52 Antibodies reactive with human T cell leukemia viruses in the serum of hemophiliacs receiving factor VIII concentrate. Blood 1985 1.21
53 Antibodies to human T-lymphotropic virus type III and development of the acquired immunodeficiency syndrome in homosexual men presenting with immune thrombocytopenia. Ann Intern Med 1986 1.19
54 Evidence for exposure to HTLV-III in Uganda before 1973. Science 1985 1.18
55 DNA polymerases of normal and neoplastic mammalian cells. Biochim Biophys Acta 1978 1.18
56 Dermatologic findings and manifestations of acquired immunodeficiency syndrome (AIDS). J Am Acad Dermatol 1987 1.17
57 Identification of simian immunodeficiency virus SIVMAC env gene products. J Virol 1989 1.16
58 Detection of human T-cell lymphotropic virus type III-related antigens and anti-human T-cell lymphotropic virus type III antibodies by anticomplementary immunofluorescence. J Clin Microbiol 1986 1.16
59 A unique human immunodeficiency virus culture secreting soluble gp160. AIDS Res Hum Retroviruses 1988 1.15
60 Mode of action of 5'-linked cholesteryl phosphorothioate oligodeoxynucleotides in inhibiting syncytia formation and infection by HIV-1 and HIV-2 in vitro. Biochemistry 1991 1.14
61 Delineation of immunoreactive, conserved regions in the external glycoprotein of the human immunodeficiency virus type 1. AIDS Res Hum Retroviruses 1992 1.12
62 Characterization of Rauscher murine leukemia virus envelope glycoprotein receptor in membranes from murine fibroblasts. J Virol 1978 1.08
63 Antibody seronegative human T-lymphotropic virus type III (HTLV-III)-infected patients with acquired immunodeficiency syndrome or related disorders. Blood 1985 1.07
64 Infection with HTLV-III/LAV and transfusion-associated acquired immunodeficiency syndrome. Serologic evidence of an association. JAMA 1985 1.06
65 Covalently crosslinked complexes of human immunodeficiency virus type 1 (HIV-1) gp120 and CD4 receptor elicit a neutralizing immune response that includes antibodies selective for primary virus isolates. Virology 1996 1.05
66 Separation of ribonuclease H and RNA directed DNA polymerase (reverse transcriptase) of murine type-C RNA tumor viruses. Proc Natl Acad Sci U S A 1974 1.05
67 Isolation and characterization of a T lymphocyte-derived differentiation inducing factor for the myeloid leukemic cell line HL-60. Blood 1984 1.05
68 Monoclonal antibodies raised against covalently crosslinked complexes of human immunodeficiency virus type 1 gp120 and CD4 receptor identify a novel complex-dependent epitope on gp 120. Virology 1995 1.04
69 Isolation and characterization of a ribonuclease from human leukemic blood cells specific for ribonucleic acid of ribonucleic acid-deoxyribonucleic acid hybrid molecules. J Biol Chem 1975 1.01
70 Safety of the hepatitis B vaccine. N Engl J Med 1985 1.01
71 Processing and secretion of envelope glycoproteins of human immunodeficiency virus type 1 in the presence of trimming glucosidase inhibitor deoxynojirimycin. Intervirology 1989 1.01
72 Neoplastic complications of HTLV-III infection. Lymphomas and solid tumors. Am J Med 1987 0.97
73 Prospective study of cytotoxic T lymphocyte responses to influenza and antibodies to human T lymphotropic virus-III in homosexual men. Selective loss of an influenza-specific, human leukocyte antigen-restricted cytotoxic T lymphocyte response in human T lymphotropic virus-III positive individuals with symptoms of acquired immunodeficiency syndrome and in a patient with acquired immunodeficiency syndrome. J Clin Invest 1985 0.95
74 Immunological properties of HTLV-III antigens recognized by sera of patients with AIDS and AIDS-related complex and of asymptomatic carriers of HTLV-III infection. Cancer Res 1985 0.95
75 Virologic studies in a case of transfusion-associated AIDS. N Engl J Med 1984 0.95
76 Reversible, pH-dependent formation of a conformer of rabbit liver fructose 1,6-diphosphatase with low catalytic activity. Biochemistry 1971 0.94
77 Reversible inactivation of rabbit liver fructose 1,6-diphosphatase by adenosine triphosphate and adenosine diphosphate. J Biol Chem 1971 0.94
78 HTLV-III and the etiology of AIDS. Prog Allergy 1986 0.93
79 Identification of the RPMI 8226 retrovirus and its dissemination as a significant contaminant of some widely used human and marmoset cell lines. Int J Cancer 1982 0.93
80 Evidence for human T cell lymphoma-leukemia virus infection of family members of human T cell lymphoma-leukemia virus positive T cell leukemia-lymphoma patients. J Exp Med 1983 0.92
81 IgM and IgG antibodies to human T cell lymphotropic retrovirus (HTLV-III) in lymphadenopathy syndrome and subjects at risk for AIDS in Italy. Br Med J (Clin Res Ed) 1985 0.92
82 Purification of rabbit liver fructose 1,6-diphosphatase by substrate elution. J Biol Chem 1970 0.91
83 Lateral diffusion of CD4 on the surface of a human neoplastic T-cell line probed with a fluorescent derivative of the envelope glycoprotein (gp120) of human immunodeficiency virus type 1 (HIV-1). J Cell Physiol 1991 0.90
84 High prevalence of serum antibodies to reverse transcriptase in HIV-1-infected individuals. AIDS Res Hum Retroviruses 1988 0.89
85 Kaposi's sarcoma in Zaire is not associated with HTLV-III infection. N Engl J Med 1984 0.88
86 Unusual features of scabies complicating human T-lymphotropic virus type III infection. J Am Acad Dermatol 1986 0.88
87 Analysis of the interaction between Rauscher murine leukemia virus and murine cell membrane receptor by in vitro binding assay. Cancer Lett 1983 0.88
88 Unexplained persistent lymphadenopathy in homosexual men and the acquired immune deficiency syndrome. Medicine (Baltimore) 1985 0.87
89 Sequential changes in antibody levels to the env and gag antigens in human immunodeficiency virus infected subjects. Eur J Epidemiol 1987 0.87
90 Low circulating thymulin-like activity in children with AIDS and AIDS-related complex. AIDS Res 1986 0.86
91 Demonstration of viral antigen p24 in circulating immune complexes of two patients with human T-cell leukaemia/lymphoma virus (HTLV) positive lymphoma. Lancet 1984 0.85
92 Human T-cell leukemia/lymphoma virus: the retrovirus of adult T-cell leukemia/lymphoma. J Infect Dis 1983 0.85
93 Inhibition by RNA of RNase H activity associated with reverse transcriptase in Rauscher murine leukemia virus cores. J Virol 1978 0.84
94 Antibodies against three purified structural proteins of the human type-C retrovirus, HTLV, in Japanese adult T-cell leukemia patients, healthy family members, and unrelated normals. Int J Cancer 1983 0.83
95 Concomitant infection with HTLV-I and HTLV-III in a patient with T8 lymphoproliferative disease. N Engl J Med 1986 0.83
96 Detection of HIV-1 infection in vitro using NASBA: an isothermal RNA amplification technique. J Virol Methods 1995 0.82
97 A papular eruption associated with human T cell lymphotropic virus type III disease. J Am Acad Dermatol 1985 0.82
98 Lymphokine production by human T cell hybridomas. J Immunol 1983 0.82
99 A comparative evaluation of methods for isolation of RNA-directed DNA polymerase from cells in a reconstituted system. Biochim Biophys Acta 1976 0.81
100 Immunological abnormalities in asymptomatic homosexual men: correlation with antibody to HTLV-III and sequential changes over two years. Q J Med 1986 0.81
101 Enzyme immunoassay using native envelope glycoprotein (gp160) for detection of human immunodeficiency virus type 1 antibodies. J Clin Microbiol 1994 0.80
102 Variability in the catalytic and allosteric properties of rabbit liver fructose 1,6-diphosphatase. The prescence of tryptophan in homogeneous enzyme. Biochem Biophys Res Commun 1972 0.79
103 Characterization of a neutralizing monoclonal antibody to the external glycoprotein of HIV-1. Intervirology 1992 0.79
104 The evidence for involvement of type C RNA tumor viruses in human acute leukemia. Cancer 1974 0.79
105 Binding of adenosine 5'-monophosphate and substrate by rabbit liver fructose 1,6-diphosphatase. Biochemistry 1969 0.79
106 Purification of envelope glycoproteins of human T cell lymphotropic virus type I (HTLV-I) by affinity chromatography. J Virol Methods 1987 0.79
107 Purification and partial characterization of human immunodeficiency virus type 2 reverse transcriptase. AIDS Res Hum Retroviruses 1989 0.79
108 Monoclonal antibodies to HTLV-III451 gp41: delineation of an immunoreactive conserved epitope in the transmembrane region of divergent isolates of HIV-1. AIDS Res Hum Retroviruses 1989 0.78
109 Effect of Evans blue and trypan blue on syncytia formation and infectivity of human immunodeficiency virus type I and type II in vitro. AIDS Res Hum Retroviruses 1991 0.78
110 Purification and partial characterization of equine infectious anemia virus reverse transcriptase. Virology 1991 0.78
111 Reversal of the adenosine triphosphate and adenosine diphosphate inactivation of liver fructose 1,6-diphosphatase by 3-phosphoglycerate. J Biol Chem 1971 0.78
112 Immunological characterization of the low molecular weight gag gene proteins p19 and p15 of human T-cell leukemia-lymphoma virus (HTLV) and demonstration of human natural antibodies to them. Virology 1984 0.78
113 Mechanism of enzyme inhibition mediated by anti-reverse transcriptase antibodies from HIV type 1-infected individuals. AIDS Res Hum Retroviruses 1994 0.78
114 Conformational perturbation of the envelope glycoprotein gp120 of human immunodeficiency virus type 1 by soluble CD4 and the lectin succinyl Con A. Virology 1993 0.78
115 Radioimmunoassay for infectious primate retrovirus reverse transcriptase: characterization, comparison with conventional immunologic assays and applicability to cellular extracts. Int J Cancer 1980 0.77
116 HTLV-III: the etiologic agent of AIDS. Princess Takamatsu Symp 1984 0.76
117 Differential viral gene expression and its effect on the biological properties of the cell clones of an HIV-1-infected cell line. Virology 1990 0.76
118 A classification of HTLV-III infection based on 75 cases seen in a suburban community. Cancer Res 1985 0.76
119 Simple affinity procedure for the purification of mammalian viral reverse transcriptases. J Virol 1980 0.75
120 Occurrence of new metabolites containing N 6 ,N 6 -dimethyladenine in spores of Streptomyces alboniger. Biochim Biophys Acta 1972 0.75
121 Screening test for HTLV-III (AIDS agent) antibodies: specificity, sensitivity, and applications. JAMA 2014 0.75
122 Correlation between exposure to human T-cell leukemia-lymphoma virus-III and the development of AIDS. Ann N Y Acad Sci 1984 0.75
123 Antibody to human T cell leukaemia virus type III in Australian homosexual men with lymphadenopathy. Med J Aust 1984 0.75
124 Prevalence of antibody to HTLV-III in homosexual men in Melbourne. Med J Aust 1986 0.75
125 Glycoprotein of human immunodeficiency virus type 1 synthesized in chronically infected Molt3 cells acquires heterogeneous oligosaccharide structures. Biochem Biophys Res Commun 1993 0.75
126 Human T-cell leukemia-lymphoma virus (HTLV): a progress report. Haematol Blood Transfus 1983 0.75
127 Mechanisms for induction of differentiation in the human promyelocytic cell line HL-60. Haematol Blood Transfus 1983 0.75
128 Interaction of C-terminal sequences of human immunodeficiency virus reverse transcriptase with template primer. J Biol Chem 1991 0.75
129 Substrate-induced conformational changes of liver fructose 1,6-diphosphatase studied with the hydrophobic probe, 1-anilinonaphthalene-8-sulfonate. J Biol Chem 1970 0.75
130 Screening tests for blood donors presumed to have transmitted the acquired immunodeficiency syndrome. Blood 1985 0.75
131 Requirement of substrate for adenosine 5'-monophosphate binding to liver fructose 1,6-diphosphatase. Biochem Biophys Res Commun 1968 0.75
132 Biochemical properties of reverse transcriptase activities from human cells and RNA tumor viruses. Johns Hopkins Med J Suppl 1973 0.75
133 Apparent transmission of human T-cell leukemia virus type III to a heterosexual woman with the acquired immunodeficiency syndrome. Ann Intern Med 1985 0.75
134 HTLV-III legend correction. Science 1986 0.75
135 High prevalence of serum antibodies to equine infectious anemia virus reverse transcriptase. AIDS Res Hum Retroviruses 1993 0.75
136 Severe molluscum contagiosum infection in a patient with human T cell lymphotrophic (HTLV-III) disease. J Am Acad Dermatol 1985 0.75
137 The human T-cell leukemia virus family, adult T cell leukemia, and AIDS. Haematol Blood Transfus 1985 0.75
138 Cell surface receptors for ecotropic murine viruses are different from those for xenotropic and amphotropic viruses. Intervirology 1983 0.75
139 T lymphocyte-derived differentiation-inducing factor inhibits proliferation of leukemic and normal hemopoietic cells. Blood 1986 0.75
140 A T lymphocyte-derived differentiation-inducing factor for myeloid leukemia cells: purification and characterization. Haematol Blood Transfus 1985 0.75
141 Purification of normal human T-cell growth factor to molecular homogeneity. Haematol Blood Transfus 1985 0.75
142 Spectrum of Kaposi's sarcoma in the epidemic of AIDS. Cancer Res 1985 0.75
143 Reverse transcriptase--a general discussion. J Enzyme Inhib 1992 0.75
144 Seroepidemiological evidence for HTLV-III infection as the primary etiologic factor for acquired immunodeficiency syndrome. Prog Clin Biol Res 1985 0.75
145 Etiology of AIDS: biological and biochemical characteristics of HTLV-III. Adv Exp Med Biol 1985 0.75
146 Immunological characterization of the natural antibodies to human T-cell leukemia virus in human sera. Haematol Blood Transfus 1983 0.75