Published in J Pharm Pharmacol on December 01, 1972
Central alpha- and beta-adrenoceptors modifying arterial blood pressure and heart rate in conscious cats. Br J Pharmacol (1974) 1.62
Cardiovascular effects of dopamine after central administration into conscious cats. Br J Pharmacol (1976) 0.78
An investigation of the tachycardia produced by intracerebro-ventricular injections of isoprenaline in mice. Br J Pharmacol (1975) 0.75
Proceedings: Comparison of some haemodynamic changes between central and intravenous administration of (plus or minus)-propranolol in anaesthetized dogs. Br J Pharmacol (1974) 0.75
Studies on RX 781094: a selective, potent and specific antagonist of alpha 2-adrenoceptors. Br J Pharmacol (1983) 2.21
Central alpha- and beta-adrenoceptors modifying arterial blood pressure and heart rate in conscious cats. Br J Pharmacol (1974) 1.62
A pharmacological analysis of the responses to transmural stimulation in isolated intestinal preparations. Br J Pharmacol Chemother (1968) 1.46
The effect of reserpine on the pressor responses to angiotensin in the conscious cat. Br J Pharmacol (1970) 1.28
Zebrafish: an emerging technology for in vivo pharmacological assessment to identify potential safety liabilities in early drug discovery. Br J Pharmacol (2008) 1.28
Tissue levels of several radiolabelled beta-adrenoceptor antagonists after intravenous administration in rats. Arch Int Pharmacodyn Ther (1979) 1.25
Comparison of the alpha-adrenoceptor antagonist profiles of idazoxan (RX 781094), yohimbine, rauwolscine and corynanthine. Naunyn Schmiedebergs Arch Pharmacol (1984) 1.21
Differential effects of prazosin on the pre- and postsynaptic alpha-adrenoceptors in the rat and dog [proceedings]. Br J Pharmacol (1977) 1.15
Effects of prazosin and phentolamine on cardiac presynaptic alpha-adrenoceptors in the cat, dog and rat. Clin Exp Hypertens (1978) 1.15
An improved valve device for the continuous measurement of arterial blood pressure in the conscious unrestrained cat. J Pharm Pharmacol (1972) 1.14
Studies on the mechanism of the vasodilator effects of prazosin in dogs and rabbits. Eur J Pharmacol (1978) 1.13
Cardiovascular dopamine receptor stimulation antagonized by metoclopramide. J Pharm Pharmacol (1975) 1.12
alpha 2-Adrenoceptor agonists induced mydriasis in the rat by an action within the central nervous system. Br J Pharmacol (1983) 1.11
Cardiovascular effects of beta-adrenoreceptor blocking agents after intracerebroventricular administration in conscious normotensive cats. Clin Exp Pharmacol Physiol (1975) 1.10
Human vascular smooth muscle cells express receptors for CC chemokines. Arterioscler Thromb Vasc Biol (1998) 1.09
Preliminary studies on SL 75212, a new potent cardioselective beta-adrenoceptor antagonist [proceedings]. Br J Pharmacol (1979) 1.06
Influence of the length of the stimulus period and frequency of sympathetic stimulation on the response of the guinea-pig isolated vas deferens to bretylium, guanethidine and amphetamine. J Pharm Pharmacol (1965) 1.03
The pharmacology of prazosin, a novel antihypertensive agent. Life Sci (1980) 1.03
An improved technique for the continuous measurement of arterial blood pressure in the conscious unrestrained cat. Br J Pharmacol (1972) 1.00
Central adrenoreceptors and the control of arterial blood pressure. Clin Exp Pharmacol Physiol (1975) 1.00
Chemokine production by human vascular smooth muscle cells: modulation by IL-13. Br J Pharmacol (1997) 0.99
-Adrenergic receptors in the central nervous system of the cat concerned with control of arterial blood pressure and heart rate. Nat New Biol (1973) 0.98
Potentiation by angiotensin of responses to endogenously released noradrenaline in the pithed rat. Arch Int Pharmacodyn Ther (1969) 0.96
Presynaptic alpha-adrenoreceptors; in vitro methods and preparations utilised in the evaluation of agonists and antagonists. J Auton Pharmacol (1980) 0.96
Characterization of alpha-adrenoceptors in the vasculature of the canine nasal mucosa. Br J Pharmacol (1986) 0.95
An adrenergic neuron blocking action of propranolol in isolated tissues. J Pharm Pharmacol (1968) 0.95
The effects of prazosin on the clonidine induced hypotension and bradycardia in rats and sedation in chicks [proceedings]. Br J Pharmacol (1978) 0.92
Reversal of clonidine induced miosis by the alpha 2-adrenoreceptor antagonist RX 781094. Br J Clin Pharmacol (1982) 0.92
Time-course analysis of the cardiovascular effects of clonidine resulting from the activation of cardiac pre- and vascular postsynaptic alpha-adrenoceptors in the pithed rat [proceedings]. Br J Pharmacol (1978) 0.92
The mechanism of the antihypertensive action of -methyldopa in hypertensive rats. Eur J Pharmacol (1973) 0.91
Selectivity and potency of 2-alkyl analogues of the alpha 2-adrenoceptor antagonist idazoxan (RX 781094) in peripheral systems. Br J Pharmacol (1984) 0.91
Effects of mianserin, desipramine and maprotiline on blood pressure responses evoked by acetylcholine, histamine and 5-hydroxytryptamine in rats. Br J Pharmacol (1981) 0.89
Pressor responses to noradrenaline administered into the third cerebral ventricle of anaesthetized and conscious cats [proceedings]. Br J Pharmacol (1976) 0.88
Indoline analogues of idazoxan: potent alpha 2-antagonists and alpha 1-agonists. J Med Chem (1988) 0.85
Functional and biochemical evidence for the lack of cardiac presynaptic alpha-2 adrenoceptor stimulant properties of cirazoline (LD 3098), a potent alpha-1 adrenoceptor agonist in dogs and rats. J Pharmacol Exp Ther (1982) 0.84
The action of isoprenaline on the perfused vessels of the rabbit ear. J Pharm Pharmacol (1971) 0.84
Interaction of angiotensin II with noradrenaline and other spasmogens on rabbit isolated aortic strips. Arch Int Pharmacodyn Ther (1976) 0.83
alpha-adrenoreceptor reagents. 1. Synthesis of some 1,4-benzodioxans as selective presynaptic alpha 2-adrenoreceptor antagonists and potential antidepressants. J Med Chem (1983) 0.83
Effects of clonidine, prazosin and phentolamine on heart rate and coronary sinus catecholamine concentration during cardioaccelerator nerve stimulation in spinal dogs. Br J Pharmacol (1979) 0.83
Alpha-adrenoreceptor reagents. 2. Effects of modification of the 1,4-benzodioxan ring system on alpha-adrenoreceptor activity. J Med Chem (1984) 0.82
Mode of action of methyldopa. J Pharm Pharmacol (1967) 0.82
The blood pressure lowering effects of intravenous versus intracerebroventricular prazosin in anaesthetised cats. Eur J Pharmacol (1978) 0.82
Comparison of mianserin with desipramine, maprotiline and phentolamine on cardiac presynaptic and vascular postsynaptic alpha-adrenoceptors and noradrenaline reuptake in pithed normotensive rats. Br J Pharmacol (1980) 0.81
Inhibitory responses to transmural stimulation in isolated intestinal preparations. J Pharm Pharmacol (1967) 0.81
Role of noradrenaline in the acute pressor response to angiotensin in conscious cats. Br J Pharmacol (1970) 0.80
Potentiation by angiotensin II of noradrenaline-induced contractions of a rabbit isolated thoracic aorta. Br J Pharmacol (1973) 0.80
Monocyte chemoattractant protein-2 is a potent agonist of CCR2B. J Leukoc Biol (1997) 0.80
The mode of action of -methyldopa. Br J Pharmacol (1972) 0.80
Comparison of cardiovascular actions of dihydralazine, phentolamine, and prazosin in spontaneously hypertensive rats. J Cardiovasc Pharmacol (1980) 0.80
Inhibition of angiotensin pressor responses with diethyl-dithiocarbamate (DDC). Br J Pharmacol (1969) 0.80
Effects of clonidine on canine cardiac neuroeffector structures controlling heart rate. Br J Pharmacol (1980) 0.79
Selective endothelin A receptor antagonists. 4. Discovery and structure-activity relationships of stilbene acid and alcohol derivatives. J Med Chem (1998) 0.79
The effect of NG-nitro-L-arginine methyl ester upon basal blood flow and endothelium-dependent vasodilatation in the dog hindlimb. Br J Pharmacol (1993) 0.79
The interaction between angiotensin and sympathetic vasoconstriction in the isolated artery of the rabbit ear. Br J Pharmacol (1968) 0.79
Sleeping times evoked by alpha adrenoceptor agonists in two-day-old chicks: an experimental model to evaluate full and partial agonists at central alpha-2 adrenoceptors. J Pharmacol Exp Ther (1983) 0.79
Proceedings: Drinking in the cat induced by centrally administered angiotensin. Br J Pharmacol (1973) 0.78
Preclinical in vitro cardiac electrophysiology: a method of predicting arrhythmogenic potential of antihistamines in humans? Drug Saf (1999) 0.78
Potentiation by metoclopramide of responses to cholinergic nerve stimulation in the isolated gastric fundus preparation of the rat [proceedings]. J Pharm Pharmacol (1977) 0.78
Selective ET(A) antagonists. 5. Discovery and structure-activity relationships of phenoxyphenylacetic acid derivatives. J Med Chem (2000) 0.78
Comparison of the effects of efaroxan and glibenclamide on plasma glucose and insulin levels in rats. Eur J Pharmacol (1992) 0.78
Mechanism of antihypertensive activity of orally administered prazosin in spontaneously hypertensive rats. J Cardiovasc Pharmacol (1980) 0.78
Effects of mianserin on noradrenaline uptake, cardiac presynaptic and vascular postsynaptic alpha-adrenoceptors in rats [proceedings]. Br J Pharmacol (1979) 0.78
The lack of crossed tachyphylaxis between tyramine and some other indirectly acting sympathomimetic amines. Br J Pharmacol Chemother (1967) 0.78
In vivo demonstration of alpha-adrenoceptor-mediated positive inotropy in pithed rats: evidence that noradrenaline does not stimulate myocardial alpha-adrenoceptors. J Auton Pharmacol (1999) 0.78
Cardiovascular effects of dopamine after central administration into conscious cats. Br J Pharmacol (1976) 0.78
Alpha-adrenoreceptor reagents. 4. Resolution of some potent selective prejunctional alpha 2-adrenoreceptor antagonists. J Med Chem (1986) 0.78
Selective endothelin A receptor antagonists. 3. Discovery and structure-activity relationships of a series of 4-phenoxybutanoic acid derivatives. J Med Chem (1998) 0.77
Effects on blood pressure of noradrenaline and isoprenaline administered into the third ventricle of the brain of anaesthetized and conscious cats. J Auton Pharmacol (1980) 0.77
Atypical antagonism observed with BQ-123 in human saphenous vein. J Cardiovasc Pharmacol (1998) 0.77
Modified cannula for intracerebroventricular injections in conscious cats. Lab Pract (1974) 0.77
Cromakalim does not protect against skeletal muscle fatigue in an anaesthetized rat model of acute hindlimb ischaemia. Eur J Pharmacol (1993) 0.77
Effects of desipramine on stimulation-induced contractions of the vas deferens of rats pretreated either chronically with desipramine or acutely with idazoxan. Clin Sci (Lond) (1985) 0.77
Selectivity profile of the alpha 2-adrenoceptor antagonist efaroxan in relation to plasma glucose and insulin levels in the rat. Eur J Pharmacol (1992) 0.77
Effect of endothelin antagonists with or without BQ 788 on ET-1 responses in pithed rats. J Cardiovasc Pharmacol (1995) 0.76
Heteroaromatic analogues of the alpha 2-adrenoreceptor partial agonist clonidine. J Med Chem (1989) 0.76
Cardiovascular effects of carbachol and other cholinomimetics administered into the cerebral ventricles of conscious cats. Clin Exp Pharmacol Physiol (1977) 0.76
Sarafotoxin S6c elicits a non-ETA or non-ETB-mediated pressor response in the pithed rat. J Cardiovasc Pharmacol (1995) 0.76
Evidence against beta-adrenoceptor blocking activity of diltiazem, a drug with calcium antagonist properties. Br J Pharmacol (1980) 0.75
Selective inhibition of angiotensin pressor responses in the pithed rat by tetraethylthiuram disulphide (disulfiram) and sodium diethyldithiocarbamate (DDC). Br J Pharmacol (1972) 0.75
Effect of centrally administered noradrenaline and isoprenaline on splanchnic nerve activity in anaesthetised and conscious cats [proceedings]. Br J Pharmacol (1978) 0.75
The effects of some gastrointestinal hormones and metoclopramide on cardiovascular dopamine receptors [proceedings]. Br J Pharmacol (1977) 0.75
Proceedings: Effect of propranolol treatment on the development of DOCA/saline hypertension in rats. Br J Pharmacol (1975) 0.75
Enhancement by angiotensin of pressor responses to endogenous noradrenaline in the pithed rat. Br J Pharmacol (1969) 0.75
Drinking behaviour in the cat induced by renin, angiotensin I, II and isoprenaline. J Physiol (1975) 0.75
Changes in plasma renin levels of normotensive and spontaneously hypertensive rats with increasing age [proceedings]. Br J Pharmacol (1978) 0.75
Cardiovascular effects of diltiazem, a calcium antagonist, on isolated heart muscle preparations and in anaesthetized and pitched rats [proceedings]. Br J Pharmacol (1978) 0.75
Comparison of methods for the determination of available lysine value in animal and vegetable protein sources. J Sci Food Agric (1967) 0.75
Determination of trace amounts of copper, zinc and magnesium in aminal feeds by atomic-absorption spectrophotometry. Analyst (1968) 0.75
Alpha 2-adrenoceptor antisecretory responses in the rat jejunum. J Auton Pharmacol (1990) 0.75
Characterisation of constrictor endothelin receptors in the human internal thoracic artery and saphenous vein. J Cardiovasc Pharmacol (1999) 0.75