Published in Lab Pract on August 01, 1974
Cardiovascular effects of dopamine after central administration into conscious cats. Br J Pharmacol (1976) 0.78
Studies on RX 781094: a selective, potent and specific antagonist of alpha 2-adrenoceptors. Br J Pharmacol (1983) 2.21
Central alpha- and beta-adrenoceptors modifying arterial blood pressure and heart rate in conscious cats. Br J Pharmacol (1974) 1.62
A pharmacological analysis of the responses to transmural stimulation in isolated intestinal preparations. Br J Pharmacol Chemother (1968) 1.46
The effect of reserpine on the pressor responses to angiotensin in the conscious cat. Br J Pharmacol (1970) 1.28
Zebrafish: an emerging technology for in vivo pharmacological assessment to identify potential safety liabilities in early drug discovery. Br J Pharmacol (2008) 1.28
Tissue levels of several radiolabelled beta-adrenoceptor antagonists after intravenous administration in rats. Arch Int Pharmacodyn Ther (1979) 1.25
Comparison of the alpha-adrenoceptor antagonist profiles of idazoxan (RX 781094), yohimbine, rauwolscine and corynanthine. Naunyn Schmiedebergs Arch Pharmacol (1984) 1.21
Differential effects of prazosin on the pre- and postsynaptic alpha-adrenoceptors in the rat and dog [proceedings]. Br J Pharmacol (1977) 1.15
Effects of prazosin and phentolamine on cardiac presynaptic alpha-adrenoceptors in the cat, dog and rat. Clin Exp Hypertens (1978) 1.15
An improved valve device for the continuous measurement of arterial blood pressure in the conscious unrestrained cat. J Pharm Pharmacol (1972) 1.14
Studies on the mechanism of the vasodilator effects of prazosin in dogs and rabbits. Eur J Pharmacol (1978) 1.13
Cardiovascular dopamine receptor stimulation antagonized by metoclopramide. J Pharm Pharmacol (1975) 1.12
alpha 2-Adrenoceptor agonists induced mydriasis in the rat by an action within the central nervous system. Br J Pharmacol (1983) 1.11
Cardiovascular effects of beta-adrenoreceptor blocking agents after intracerebroventricular administration in conscious normotensive cats. Clin Exp Pharmacol Physiol (1975) 1.10
Human vascular smooth muscle cells express receptors for CC chemokines. Arterioscler Thromb Vasc Biol (1998) 1.09
Preliminary studies on SL 75212, a new potent cardioselective beta-adrenoceptor antagonist [proceedings]. Br J Pharmacol (1979) 1.06
Influence of the length of the stimulus period and frequency of sympathetic stimulation on the response of the guinea-pig isolated vas deferens to bretylium, guanethidine and amphetamine. J Pharm Pharmacol (1965) 1.03
The pharmacology of prazosin, a novel antihypertensive agent. Life Sci (1980) 1.03
An improved technique for the continuous measurement of arterial blood pressure in the conscious unrestrained cat. Br J Pharmacol (1972) 1.00
Central adrenoreceptors and the control of arterial blood pressure. Clin Exp Pharmacol Physiol (1975) 1.00
Adrenoceptors in the central nervous system concerned with cardiovascular control. J Pharm Pharmacol (1972) 0.99
Chemokine production by human vascular smooth muscle cells: modulation by IL-13. Br J Pharmacol (1997) 0.99
-Adrenergic receptors in the central nervous system of the cat concerned with control of arterial blood pressure and heart rate. Nat New Biol (1973) 0.98
Potentiation by angiotensin of responses to endogenously released noradrenaline in the pithed rat. Arch Int Pharmacodyn Ther (1969) 0.96
Presynaptic alpha-adrenoreceptors; in vitro methods and preparations utilised in the evaluation of agonists and antagonists. J Auton Pharmacol (1980) 0.96
Characterization of alpha-adrenoceptors in the vasculature of the canine nasal mucosa. Br J Pharmacol (1986) 0.95
Cardiovascular effects of the novel arteriovenous dilator agent, flosequinan in conscious dogs and cats. Br J Pharmacol (1988) 0.95
An adrenergic neuron blocking action of propranolol in isolated tissues. J Pharm Pharmacol (1968) 0.95
The effects of prazosin on the clonidine induced hypotension and bradycardia in rats and sedation in chicks [proceedings]. Br J Pharmacol (1978) 0.92
Reversal of clonidine induced miosis by the alpha 2-adrenoreceptor antagonist RX 781094. Br J Clin Pharmacol (1982) 0.92
Time-course analysis of the cardiovascular effects of clonidine resulting from the activation of cardiac pre- and vascular postsynaptic alpha-adrenoceptors in the pithed rat [proceedings]. Br J Pharmacol (1978) 0.92
The mechanism of the antihypertensive action of -methyldopa in hypertensive rats. Eur J Pharmacol (1973) 0.91
Selectivity and potency of 2-alkyl analogues of the alpha 2-adrenoceptor antagonist idazoxan (RX 781094) in peripheral systems. Br J Pharmacol (1984) 0.91
Effects of mianserin, desipramine and maprotiline on blood pressure responses evoked by acetylcholine, histamine and 5-hydroxytryptamine in rats. Br J Pharmacol (1981) 0.89
Pressor responses to noradrenaline administered into the third cerebral ventricle of anaesthetized and conscious cats [proceedings]. Br J Pharmacol (1976) 0.88
Indoline analogues of idazoxan: potent alpha 2-antagonists and alpha 1-agonists. J Med Chem (1988) 0.85
Functional and biochemical evidence for the lack of cardiac presynaptic alpha-2 adrenoceptor stimulant properties of cirazoline (LD 3098), a potent alpha-1 adrenoceptor agonist in dogs and rats. J Pharmacol Exp Ther (1982) 0.84
The action of isoprenaline on the perfused vessels of the rabbit ear. J Pharm Pharmacol (1971) 0.84
Interaction of angiotensin II with noradrenaline and other spasmogens on rabbit isolated aortic strips. Arch Int Pharmacodyn Ther (1976) 0.83
alpha-adrenoreceptor reagents. 1. Synthesis of some 1,4-benzodioxans as selective presynaptic alpha 2-adrenoreceptor antagonists and potential antidepressants. J Med Chem (1983) 0.83
Effects of clonidine, prazosin and phentolamine on heart rate and coronary sinus catecholamine concentration during cardioaccelerator nerve stimulation in spinal dogs. Br J Pharmacol (1979) 0.83
Mode of action of methyldopa. J Pharm Pharmacol (1967) 0.82
Alpha-adrenoreceptor reagents. 2. Effects of modification of the 1,4-benzodioxan ring system on alpha-adrenoreceptor activity. J Med Chem (1984) 0.82
The blood pressure lowering effects of intravenous versus intracerebroventricular prazosin in anaesthetised cats. Eur J Pharmacol (1978) 0.82
Comparison of mianserin with desipramine, maprotiline and phentolamine on cardiac presynaptic and vascular postsynaptic alpha-adrenoceptors and noradrenaline reuptake in pithed normotensive rats. Br J Pharmacol (1980) 0.81
Inhibitory responses to transmural stimulation in isolated intestinal preparations. J Pharm Pharmacol (1967) 0.81
Potentiation by angiotensin II of noradrenaline-induced contractions of a rabbit isolated thoracic aorta. Br J Pharmacol (1973) 0.80
BTS 39542, a dihydrophthalazin-1-ylacetic acid with high efficacy diuretic activity. Br J Pharmacol (1981) 0.80
Inhibition of angiotensin pressor responses with diethyl-dithiocarbamate (DDC). Br J Pharmacol (1969) 0.80
Role of noradrenaline in the acute pressor response to angiotensin in conscious cats. Br J Pharmacol (1970) 0.80
Monocyte chemoattractant protein-2 is a potent agonist of CCR2B. J Leukoc Biol (1997) 0.80
The mode of action of -methyldopa. Br J Pharmacol (1972) 0.80
Comparison of cardiovascular actions of dihydralazine, phentolamine, and prazosin in spontaneously hypertensive rats. J Cardiovasc Pharmacol (1980) 0.80
The interaction between angiotensin and sympathetic vasoconstriction in the isolated artery of the rabbit ear. Br J Pharmacol (1968) 0.79
Sleeping times evoked by alpha adrenoceptor agonists in two-day-old chicks: an experimental model to evaluate full and partial agonists at central alpha-2 adrenoceptors. J Pharmacol Exp Ther (1983) 0.79
The effect of NG-nitro-L-arginine methyl ester upon basal blood flow and endothelium-dependent vasodilatation in the dog hindlimb. Br J Pharmacol (1993) 0.79
Selective endothelin A receptor antagonists. 4. Discovery and structure-activity relationships of stilbene acid and alcohol derivatives. J Med Chem (1998) 0.79
Effects of clonidine on canine cardiac neuroeffector structures controlling heart rate. Br J Pharmacol (1980) 0.79
Preclinical in vitro cardiac electrophysiology: a method of predicting arrhythmogenic potential of antihistamines in humans? Drug Saf (1999) 0.78
Comparison of the effects of efaroxan and glibenclamide on plasma glucose and insulin levels in rats. Eur J Pharmacol (1992) 0.78
Selective ET(A) antagonists. 5. Discovery and structure-activity relationships of phenoxyphenylacetic acid derivatives. J Med Chem (2000) 0.78
Potentiation by metoclopramide of responses to cholinergic nerve stimulation in the isolated gastric fundus preparation of the rat [proceedings]. J Pharm Pharmacol (1977) 0.78
Effects of mianserin on noradrenaline uptake, cardiac presynaptic and vascular postsynaptic alpha-adrenoceptors in rats [proceedings]. Br J Pharmacol (1979) 0.78
In vivo demonstration of alpha-adrenoceptor-mediated positive inotropy in pithed rats: evidence that noradrenaline does not stimulate myocardial alpha-adrenoceptors. J Auton Pharmacol (1999) 0.78
Proceedings: Drinking in the cat induced by centrally administered angiotensin. Br J Pharmacol (1973) 0.78
Alpha-adrenoreceptor reagents. 4. Resolution of some potent selective prejunctional alpha 2-adrenoreceptor antagonists. J Med Chem (1986) 0.78
The lack of crossed tachyphylaxis between tyramine and some other indirectly acting sympathomimetic amines. Br J Pharmacol Chemother (1967) 0.78
Mechanism of antihypertensive activity of orally administered prazosin in spontaneously hypertensive rats. J Cardiovasc Pharmacol (1980) 0.78
Cardiovascular effects of dopamine after central administration into conscious cats. Br J Pharmacol (1976) 0.78
Effects of desipramine on stimulation-induced contractions of the vas deferens of rats pretreated either chronically with desipramine or acutely with idazoxan. Clin Sci (Lond) (1985) 0.77
Atypical antagonism observed with BQ-123 in human saphenous vein. J Cardiovasc Pharmacol (1998) 0.77
Selectivity profile of the alpha 2-adrenoceptor antagonist efaroxan in relation to plasma glucose and insulin levels in the rat. Eur J Pharmacol (1992) 0.77
Effects on blood pressure of noradrenaline and isoprenaline administered into the third ventricle of the brain of anaesthetized and conscious cats. J Auton Pharmacol (1980) 0.77
Cromakalim does not protect against skeletal muscle fatigue in an anaesthetized rat model of acute hindlimb ischaemia. Eur J Pharmacol (1993) 0.77
Selective endothelin A receptor antagonists. 3. Discovery and structure-activity relationships of a series of 4-phenoxybutanoic acid derivatives. J Med Chem (1998) 0.77
Heteroaromatic analogues of the alpha 2-adrenoreceptor partial agonist clonidine. J Med Chem (1989) 0.76
Effect of endothelin antagonists with or without BQ 788 on ET-1 responses in pithed rats. J Cardiovasc Pharmacol (1995) 0.76
Cardiovascular effects of carbachol and other cholinomimetics administered into the cerebral ventricles of conscious cats. Clin Exp Pharmacol Physiol (1977) 0.76
Sarafotoxin S6c elicits a non-ETA or non-ETB-mediated pressor response in the pithed rat. J Cardiovasc Pharmacol (1995) 0.76
Proceedings: Effect of propranolol treatment on the development of DOCA/saline hypertension in rats. Br J Pharmacol (1975) 0.75
An investigation of the sex difference in the diuretic response to ethacrynic acid in mice. Br J Pharmacol (1977) 0.75
Changes in plasma renin levels of normotensive and spontaneously hypertensive rats with increasing age [proceedings]. Br J Pharmacol (1978) 0.75
Effects of prostaglandin synthetase inhibition on natriuresis induced by diuretics and sodium loading in the rat [proceedings]. Br J Pharmacol (1978) 0.75
Drinking behaviour in the cat induced by renin, angiotensin I, II and isoprenaline. J Physiol (1975) 0.75
Selective inhibition of angiotensin pressor responses in the pithed rat by tetraethylthiuram disulphide (disulfiram) and sodium diethyldithiocarbamate (DDC). Br J Pharmacol (1972) 0.75
Enhancement by angiotensin of pressor responses to endogenous noradrenaline in the pithed rat. Br J Pharmacol (1969) 0.75
The effects of some gastrointestinal hormones and metoclopramide on cardiovascular dopamine receptors [proceedings]. Br J Pharmacol (1977) 0.75
Evidence against beta-adrenoceptor blocking activity of diltiazem, a drug with calcium antagonist properties. Br J Pharmacol (1980) 0.75
Cardiovascular effects of diltiazem, a calcium antagonist, on isolated heart muscle preparations and in anaesthetized and pitched rats [proceedings]. Br J Pharmacol (1978) 0.75