Published in J Immunol on May 01, 1974
Infectious diseases associated with complement deficiencies. Clin Microbiol Rev (1991) 4.01
The role of specific antibody in alternative complement pathway-mediated opsonophagocytosis of type III, group B Streptococcus. J Exp Med (1980) 3.48
Opsonic requirements for staphylococcal phagocytosis. Heterogeneity among strains. Immunology (1977) 2.73
A quantitative analysis of the interactions of antipneumococcal antibody and complement in experimental pneumococcal bacteremia. J Clin Invest (1982) 2.33
Pneumococcal type-associated variability in alternate complement pathway activation. Infect Immun (1975) 2.32
Minimization of bacterial size allows for complement evasion and is overcome by the agglutinating effect of antibody. Cell Host Microbe (2011) 2.03
Classical and alternative complement pathway activation by pneumococci. Infect Immun (1977) 1.54
Complement system in pneumococcal infections. Infect Immun (1976) 1.50
Consumptive opsoninopathy: possible pathogenesis in lethal and opportunistic infections. Ann Surg (1976) 1.27
Changes in humoral components of host defense following burn trauma. Ann Surg (1977) 1.20
Molecular and functional characteristics of a protective human monoclonal antibody to serotype 8 Streptococcus pneumoniae capsular polysaccharide. Infect Immun (1999) 1.13
Facilitation of complement-dependent killing of the Lyme disease spirochete, Borrelia burgdorferi, by specific immunoglobulin G Fab antibody fragments. Infect Immun (1993) 1.08
Influence of surface modulations by enzymes and monoclonal antibodies on alternative complement pathway activation by Yersinia enterocolitica. Infect Immun (1989) 1.03
Modulation of polymorphonuclear cell interleukin-8 secretion by human monoclonal antibodies to type 8 pneumococcal capsular polysaccharide. Infect Immun (2003) 0.99
Direct evidence that decreased serum opsonization of Streptococcus pneumoniae via the alternative complement pathway in sickle cell disease is related to antibody deficiency. J Clin Invest (1987) 0.92
Evaluation of Streptococcus pneumoniae type XIV opsonins by phagocytosis-associated chemiluminescence and a bactericidal assay. Infect Immun (1982) 0.84
Effect of intravenously injected killed pneumococci on leukocytes, complement, and phagocytosis in rabbits. Infect Immun (1980) 0.83
Alterations in serum opsonic activity and complement levels in pneumococcal disease. Infect Immun (1980) 0.79
Restoration by normal human immunoglobulin G of deficient serum opsonization for Streptococcus pneumoniae in sickle cell disease. Infect Immun (1981) 0.78
Relationships between alternative complement pathway activation, C-reactive protein, and pneumococcal infection. J Clin Microbiol (1986) 0.76
A genetic map of the mouse suitable for typing intraspecific crosses. Genetics (1992) 8.53
Interactions of the complement system with endotoxic lipopolysaccharide: consumption of each of the six terminal complement components. J Exp Med (1968) 4.19
Chemotactic and anaphylatoxic fragment cleaved from the fifth component of guinea pig complement. Science (1968) 3.69
Lack of the burst firing of thalamocortical relay neurons and resistance to absence seizures in mice lacking alpha(1G) T-type Ca(2+) channels. Neuron (2001) 3.37
Heat labile opsonins to Pneumococcus. 3. The participation of immunoglobulin and of the alternate pathway of C3 activation. J Immunol (1972) 2.89
Reaction of a cobra venom factor with guinea pig complement and generation of an activity chemotactic for polymorphonuclear leukocytes. Proc Soc Exp Biol Med (1969) 2.76
The biologic activities of guinea pig antibodies. II. Modes of complement interaction with gamma 1 and gamma 2-immunoglobulins. J Immunol (1970) 2.70
Deficiency of pneumococcal serum opsonizing activity in sickle-cell disease. N Engl J Med (1968) 2.61
Production of tumor necrosis factor and other cytokines by astrocytes stimulated with lipopolysaccharide or a neurotropic virus. Proc Natl Acad Sci U S A (1989) 2.56
A neutrophil chemotatic factor derived from C'5 upon interaction of guinea pig serum with endotoxin. J Immunol (1969) 2.54
Activation of the alternative complement pathway by pneumococcal cell wall teichoic acid. J Immunol (1978) 2.40
A multiinstitutional survey of the Wiskott-Aldrich syndrome. J Pediatr (1994) 2.39
Heat labile opsonins to pneumococcus. II. Involvement of C3 and C5. J Exp Med (1969) 2.38
An unusual coding sequence from a Drosophila clock gene is conserved in vertebrates. Nature (1985) 2.25
Myasthenia gravis. Study of humoral immune mechanisms by passive transfer to mice. N Engl J Med (1977) 2.23
Ablation of P/Q-type Ca(2+) channel currents, altered synaptic transmission, and progressive ataxia in mice lacking the alpha(1A)-subunit. Proc Natl Acad Sci U S A (1999) 2.23
Production of cytotoxic factor for oligodendrocytes by stimulated astrocytes. J Immunol (1987) 2.22
A chemotactic factor for mononuclear leukocytes. Proc Soc Exp Biol Med (1971) 2.18
Significance of complement to the mechanism of action of endotoxin. Curr Top Microbiol Immunol (1969) 2.18
Nonvenereal transmission of gonococcal infections to children. J Pediatr (1971) 2.06
Surface determinants of Haemophilus influenzae pathogenicity: comparative virulence of capsular transformants in normal and complement-depleted rats. J Infect Dis (1983) 2.06
The role of complement in the host's defense against Streptococcus pneumoniae. Rev Infect Dis (1981) 2.06
The antifungal drug clotrimazole. Acta Crystallogr C (1998) 1.98
Thrombin-induced gap formation in confluent endothelial cell monolayers in vitro. Blood (1983) 1.95
An alternate complement pathway: C-3 cleaving activity, not due to C4,2a, on endotoxic lipopolysaccharide after treatment with guinea pig serum; relation to properdin. Proc Natl Acad Sci U S A (1971) 1.89
Activation of the alternative pathway by pneumococcal cell walls. J Immunol (1977) 1.89
Francisella philomiragia sepsis in chronic granulomatous disease. Pediatr Infect Dis J (1997) 1.88
X-linked agammaglobulinemia: an analysis of 96 patients. Medicine (Baltimore) (1985) 1.85
Kinetic studies of the formation of the properdin system enzymes on zymosan: evidence that nascent C3b controls the rate of assembly. J Immunol (1974) 1.82
The role of the capsular polysaccharide in the activation of the alternative pathway by the pneumococcus. J Immunol (1976) 1.80
Pseudomonas cepacia: an emerging pathogen in chronic granulomatous disease. J Pediatr (1986) 1.79
Hyaluronan fragments activate an NF-kappa B/I-kappa B alpha autoregulatory loop in murine macrophages. J Exp Med (1996) 1.75
Gene mapping within the T/t complex of the mouse. II. Anomalous position of the H-2 complex in t haplotypes. Cell (1982) 1.73
Studies of complement complex C5b,6 eluted from--EAC-6: reaction of C5b,6 with EAC4b,3b and evidence on the role of C2a and C3b in the activation of C5. J Immunol (1974) 1.73
Chronic rotavirus infection in immunodeficiency. J Pediatr (1980) 1.66
Phospholipase C isozymes selectively couple to specific neurotransmitter receptors. Nature (1997) 1.66
Kinetic analysis of 1,2-diacylglycerol mass levels in cultured fibroblasts. Comparison of stimulation by alpha-thrombin and epidermal growth factor. J Biol Chem (1988) 1.66
Carrier detection in X-linked agammaglobulinemia by analysis of X-chromosome inactivation. N Engl J Med (1987) 1.63
Host defense molecule polymorphisms influence the risk for immune-mediated complications in chronic granulomatous disease. J Clin Invest (1998) 1.58
Activation of C3 via the alternative complement pathway results in fixation of C3b to the pneumococcal cell wall. J Immunol (1980) 1.54
Sarcoidosis and common variable immunodeficiency. Report of 8 cases and review of the literature. Medicine (Baltimore) (1996) 1.53
The fixation of guinea pig complement by gamma 1 and gamma 2 immunoglobulins. J Immunol (1969) 1.52
Activation of the alternative complement pathway by Haemophilus influenzae type B. Infect Immun (1977) 1.46
Frequency dependence of impedances at the acupuncture point Quze (PC3). IEEE Eng Med Biol Mag (2002) 1.46
Requirement for the L-type Ca(2+) channel alpha(1D) subunit in postnatal pancreatic beta cell generation. J Clin Invest (2001) 1.46
Construction of a bifunctional mRNA in the mouse by using the internal ribosomal entry site of the encephalomyocarditis virus. Mol Cell Biol (1992) 1.46
Consequences of the delayed diagnosis of ataxia-telangiectasia. Pediatrics (1998) 1.44
Opsonins: their function, identity, and clinical significance. J Pediatr (1973) 1.42
Tyrosine phosphorylation of phospholipase C-gamma 1 induced by cross-linking of the high-affinity or low-affinity Fc receptor for IgG in U937 cells. Proc Natl Acad Sci U S A (1992) 1.42
Platelet activating factor inhibition reduces lung injury after cardiopulmonary bypass. Ann Thorac Surg (1995) 1.42
Neutrophil depletion limited to reperfusion reduces myocardial infarct size after 90 minutes of ischemia. Evidence for neutrophil-mediated reperfusion injury. Circulation (1989) 1.40
The effect of complement depletion on the course of Sindbis virus infection in mice. J Immunol (1978) 1.38
The role of C3 as an opsonin in the early stages of infection. Proc Soc Exp Biol Med (1975) 1.38
Reconstitution of B and T lymphocyte function in severe combined immunodeficiency disease after transplantation with thymic epithelium. Lancet (1976) 1.35
Regulation of phospholipase C-beta 3 activity by Na+/H+ exchanger regulatory factor 2. J Biol Chem (2000) 1.35
The fifth component of the guinea pig complement system. II. Mechanism of SAC1,4,2,3,5b formation and C5 consumption by EAC1,4,2,3. J Immunol (1971) 1.34
Characterization and virulence analysis of catalase mutants of Haemophilus influenzae. Infect Immun (1994) 1.34
Evidence for the involvement of the Ss protein of the mouse in the hemolytic complement system. J Exp Med (1975) 1.34
Direct evidence for the existence of nominal antigen binding sites on T cell surface Ti alpha-beta heterodimers of MHC-restricted T cell clones. Cell (1986) 1.32
Carrier detection in the Wiskott Aldrich syndrome. Blood (1988) 1.32
Oral administration of human serum immunoglobulin in immunodeficient patients with viral gastroenteritis. A pharmacokinetic and functional analysis. J Clin Invest (1985) 1.31
Participation of complement in the nonimmune host defense against experimental Haemophilus influenzae type b septicemia and meningitis. Infect Immun (1976) 1.29
Antibody-mediated suppression of grafted lymphoma cells. I. Participation of a host factor(s) other than complement. Proc Soc Exp Biol Med (1972) 1.29
Safety and immunogenicity of heptavalent pneumococcal vaccine conjugated to CRM(197) among infants with sickle cell disease. Pneumococcal Conjugate Vaccine Study Group. Pediatrics (2000) 1.26
Oropharyngeal dysphagia and aspiration in patients with ataxia-telangiectasia. J Pediatr (2000) 1.25
Tumor necrosis factor-mediated cytotoxicity involves ADP-ribosylation. J Immunol (1988) 1.24
The antimorphic nature of the Tc allele at the mouse T locus. Genetics (1988) 1.24
The role of complement in viral infections. II. the clearance of Sindbis virus from the bloodstream and central nervous system of mice depleted of complement. J Infect Dis (1980) 1.23
A novel Bcl-2 related gene, Bfl-1, is overexpressed in stomach cancer and preferentially expressed in bone marrow. Oncogene (1995) 1.23
PLC-beta1, activated via mGluRs, mediates activity-dependent differentiation in cerebral cortex. Nat Neurosci (2001) 1.22
A specific method for purification of the second component of guinea pig complement and a chemical evaluation of the one-hit theory. J Immunol (1970) 1.21
The role of complement in viral infections. III. Activation of the classical and alternative complement pathways by Sindbis virus. J Immunol (1980) 1.20
Inversion in the H-2 complex of t-haplotypes in mice. Nature (1984) 1.19
Host modification of Sindbis virus sialic acid content influences alternative complement pathway activation and virus clearance. J Immunol (1981) 1.19
The fifth component of the guinea pig complement system. 3. Dissociation and transfer of C5b, and the probable site of C5b fixation. J Immunol (1971) 1.18
The interaction of nominal antigen with T cell antigen receptors. I. Specific binding of multivalent nominal antigen to cytolytic T cell clones. J Immunol (1985) 1.17
The third component of the guinea pig complement system. I. Purification and characterization. Biochemistry (1968) 1.16
Enzyme-linked immunosorbent assay for detection and quantitation of capsular antigen of Haemophilus influenzae type b. Infect Immun (1978) 1.15
Complement and the host's defense against the pneumococcus. Crit Rev Microbiol (1984) 1.15
Adenosine deaminase deficiency in adults. Blood (1997) 1.15
Defective antigen-induced lymphocyte proliferation in the X-linked hyper-IgM syndrome. J Pediatr (1997) 1.14
Lack of protective effect of autotransplanted splenic tissue to pneumococcal challenge. Blood (1978) 1.12
Lymphocyte-activating factor. I. Generation and physicochemical characterization. J Immunol (1978) 1.12
A novel function of IL-12p40 as a chemotactic molecule for macrophages. J Immunol (1999) 1.12
Association of homozygous C4B deficiency with bacterial meningitis. J Infect Dis (1989) 1.10
Natural immunity to bacterial infections: the relation of complement to heat-labile opsonins. Proc Natl Acad Sci U S A (1969) 1.10
Foregut duplication cyst of the stomach. Pathol Int (2000) 1.10
Targeted disruption of the Ca2+ channel beta3 subunit reduces N- and L-type Ca2+ channel activity and alters the voltage-dependent activation of P/Q-type Ca2+ channels in neurons. Proc Natl Acad Sci U S A (1998) 1.09
Enhanced hippocampal CA1 LTP but normal spatial learning in inositol 1,4,5-trisphosphate 3-kinase(A)-deficient mice. Learn Mem (1999) 1.09
Single amino acid substitutions of alpha 1-antitrypsin that confer enhancement in thermal stability. J Biol Chem (1994) 1.09
Participation of complement in host defense against encapsulated Haemophilus influenzae types a, c, and d. Infect Immun (1982) 1.08
Altered nociceptive response in mice deficient in the alpha(1B) subunit of the voltage-dependent calcium channel. Mol Cell Neurosci (2001) 1.08
Mechanism of macrophage-mediated cytotoxicity: production of a soluble cytotoxic factor. J Immunol (1983) 1.07
Selective attraction of eosinophils and synergism between eosinophil chemotactic factor of anaphylaxis (ECF-A) and a fragment cleaved from the fifth component of complement (C5a). Immunology (1973) 1.07
Role of C3 in humoral immunity. Defective antibody production in C3-deficient dogs. J Immunol (1988) 1.07