Published in N Engl J Med on July 27, 1967
Failure of cytotoxic drugs to suppress immune responses of patients with rheumatoid arthritis. Ann Rheum Dis (1970) 2.42
The human primary immune response to keyhole limpet haemocyanin: interrelationships of delayed hypersensitivity, antibody response and in vitro blast transformation. Clin Exp Immunol (1970) 2.40
Measurement of antibody-producing capacity in man. I. The normal response to flagellin from Salmonella adelaide. Clin Exp Immunol (1969) 1.76
Clinically evident, non-terminal infections with herpesviruses and the wart virus in immunosuppressed renal allograft recipients. Br Med J (1970) 1.74
Anti-lymphocytic antibody and autoimmune disease: a review. Clin Exp Immunol (1969) 1.53
The human secondary immune response to Keyhole limpet haemocyanin. Clin Exp Immunol (1972) 1.15
Immunoglobulin classes of antibodies produced in the primary and secondary responses in man. Clin Exp Immunol (1969) 1.12
A comparison of immunosuppressive and anti-inflammatory agents in the rat. Clin Exp Immunol (1971) 1.09
Studies on the anti-inflammatory action of 6-mercaptopurine. J Exp Med (1968) 1.06
Asymptomatic primary biliary cirrhosis. Gut (1973) 1.05
Azathioprine: an adjunct to surgical therapy of granulomatous enteritis. Ann Surg (1970) 1.04
Measurement of antibody-producing capacity in man. V. Immunoglobulin classes of antibodies to flagellin. Immunology (1972) 1.01
Azathioprine metabolism in kidney transplant recipients. Br J Clin Pharmacol (1984) 0.98
Immunosuppression in the treatment of inflammatory bowel disease. II. The effects of azathioprine on lymphoid cell populations in a double blind trial in ulcerative colitis. Clin Exp Immunol (1976) 0.96
Prolonged thoracic-duct drainage in rheumatoid arthritis and systemic lupus erythematosus. West J Med (1979) 0.93
The primary immune response to haemocyanin in patients with primary biliary cirrhosis. Clin Exp Immunol (1973) 0.92
Humoral anti-KLH responses in cancer patients treated with dendritic cell-based immunotherapy are dictated by different vaccination parameters. Cancer Immunol Immunother (2012) 0.92
A comparative study of the action of cyclophosphamide and procarbazine on the antibody production in mice. Clin Exp Immunol (1973) 0.90
Measurement of antibody-producing capacity to flagellin in man. IV. Studies in autoimmune disease, allergy and after azathioprine treatment. Clin Exp Immunol (1971) 0.90
Wound infections in renal transplant wounds: pathogenetic and prognostic factors. Ann Surg (1975) 0.88
A comparative study of the effects of anti-tumour and immunosuppressive drugs on antibody-forming and erythropoietic cells. Clin Exp Immunol (1970) 0.87
Immune function in multiple myeloma: impaired responsiveness to keyhole limpet hemocyanin. Can Med Assoc J (1971) 0.86
The effect of azathioprine on gammaglobulin synthesis in man. J Clin Invest (1972) 0.85
Basophils in tuberculin and "Jones-Mote" delayed reactions of humans. J Clin Invest (1976) 0.85
Monomorphic post-transplant lymphoproliferative disorder of the tongue: case report and review of literature. Diagn Pathol (2007) 0.84
Cyclophosphamide in the nephrotic syndrome of childhood: its use in two groups of patients defined by clinical, light microscopic and immunopathologic findings. Can Med Assoc J (1968) 0.81
Normal human IgG with antibody activity for keyhole limpet haemocyanin. Immunology (1973) 0.80
Immunosuppressive therapy in polymyositis. J Neurol Neurosurg Psychiatry (1971) 0.80
Serum IgG and renal transplantation. Br Med J (1973) 0.79
Keyhole limpet haemocyanin - a model antigen for human immunotoxicological studies. Br J Clin Pharmacol (2014) 0.78
Relative importance of cellular and humoral immunity in human renal transplantation. Ann Surg (1971) 0.78
The effect of azathioprine on cell-mediated immunity (CMI) to Candida albicans in Crohn's disease. Clin Exp Immunol (1977) 0.77
[Immunosuppressive therapy of pemphigus vulgaris. Preliminary results of azathioprine (Imuran) treatment)]. Arch Klin Exp Dermatol (1969) 0.77
Suppression of the immune response. J Med Genet (1971) 0.75
Response to cutaneous immunization with low-molecular-weight subunit keyhole limpet hemocyanin. Int Arch Allergy Immunol (2011) 0.75
Hodgkin's disease complicated by infection with Mycobacterium kansasii. Can Med Assoc J (1969) 0.75
Monitoring of dynamic changes in Keyhole Limpet Hemocyanin (KLH)-specific B cells in KLH-vaccinated cancer patients. Sci Rep (2017) 0.75
Proceedings: Controlled trial of azathioprine in rheumatoid vasculitis. Ann Rheum Dis (1973) 0.75
Problems with immunosuppressive agents in renal disease. J Clin Pathol Suppl (R Coll Pathol) (1975) 0.75
Antimyelin antibody in multiple sclerosis: no change during immunosuppression. J Neurol Neurosurg Psychiatry (1977) 0.75
Mercaptopurine-dependent remission of nephrotic syndrome. Br Med J (1970) 0.75
Canine early immunohistological responses to cardiac transplants. J Natl Med Assoc (1970) 0.75
Abnormal lymphocyte function is secondary to drug-induced autoimmunity. Ann Rheum Dis (1976) 0.75
Characterization of the impaired antipneumococcal polysacharide antibody production in immunosuppressed pediatric patients following cardiac transplantation. J Clin Immunol (2001) 0.75
Coronary artery calcium area by electron-beam computed tomography and coronary atherosclerotic plaque area. A histopathologic correlative study. Circulation (1995) 5.90
Polyspecific monoclonal lupus autoantibodies reactive with both polynucleotides and phospholipids. J Exp Med (1981) 5.48
Polyspecificity of monoclonal lupus autoantibodies produced by human-human hybridomas. N Engl J Med (1983) 4.43
Marked inflammatory sequelae to implantation of biodegradable and nonbiodegradable polymers in porcine coronary arteries. Circulation (1996) 3.82
Arterial calcification and not lumen stenosis is highly correlated with atherosclerotic plaque burden in humans: a histologic study of 723 coronary artery segments using nondecalcifying methodology. J Am Coll Cardiol (1998) 3.67
Racial profiling in medical research. N Engl J Med (2001) 3.25
Vulnerable plaque: pathobiology and clinical implications. Ann Intern Med (1998) 3.04
Idiotypic cross-reactions of monoclonal human lupus autoantibodies. J Exp Med (1983) 2.96
Antigen-binding diversity and idiotypic cross-reactions among hybridoma autoantibodies to DNA. J Immunol (1981) 2.83
Pathology of acute and chronic coronary stenting in humans. Circulation (1999) 2.78
Hybridoma autoantibodies to DNA. J Immunol (1980) 2.76
Jumping genes. N Engl J Med (1995) 2.69
Pregnancy-associated plasma protein A as a marker of acute coronary syndromes. N Engl J Med (2001) 2.52
Expression of leukemogenic recombinant viruses associated with a recessive gene in HRS/J mice. J Exp Med (1980) 2.38
Origins of anti-DNA autoantibodies. J Clin Invest (1985) 2.26
Long-term prognostic value of coronary calcification detected by electron-beam computed tomography in patients undergoing coronary angiography. Circulation (2001) 2.26
Production of autoantibodies by human-human hybridomas. J Clin Invest (1982) 2.22
The immunoglobulin sequence. I. Arrest by 6-mercaptopurine and restitution by antibody, antigen or splenectomy. J Immunol (1965) 2.18
Carcinoembryonic antigen-antibody complexes in a patient with colonic carcinoma and nephrotic syndrome. N Engl J Med (1973) 2.15
Adventitial vasa vasorum in balloon-injured coronary arteries: visualization and quantitation by a microscopic three-dimensional computed tomography technique. J Am Coll Cardiol (1998) 2.12
Recombinant factor VIII for the treatment of previously untreated patients with hemophilia A. Safety, efficacy, and development of inhibitors. Kogenate Previously Untreated Patient Study Group. N Engl J Med (1993) 2.09
Anti-DNA antibody idiotypes in systemic lupus erythematosus. Lancet (1984) 2.08
A high frequency idiotypic marker of anti-DNA autoantibodies in MRL-Ipr/Ipr mice. J Immunol (1982) 2.05
Noninvasive evaluation of a novel swine model of renal artery stenosis. J Am Soc Nephrol (1999) 1.96
Malignant lymphomas following allogenic disease: transition from an immunological to a neoplastic disorder. Science (1965) 1.92
Immunoregulation, oncogenic viruses, and malignant lymphomas. Lancet (1972) 1.90
A single germline VH gene segment of normal A/J mice encodes autoantibodies characteristic of systemic lupus erythematosus. J Exp Med (1986) 1.87
Familial abnormalities of suppressor-cell function in systemic lupus erythematosus. N Engl J Med (1979) 1.87
Responsiveness of autoimmune and normal mice to nucleic acid antigens. J Immunol (1984) 1.85
Activation of leukemia viruses by graft-versus-host and mixed lymphocyte reactions in vitro. Proc Natl Acad Sci U S A (1972) 1.85
Exercise: effects on physical functional performance in independent older adults. J Gerontol A Biol Sci Med Sci (1999) 1.83
The restenosis paradigm revisited: an alternative proposal for cellular mechanisms. J Am Coll Cardiol (1992) 1.79
Lower-body adiposity and metabolic protection in postmenopausal women. J Clin Endocrinol Metab (2005) 1.78
Binding of cytoskeletal proteins by monoclonal anti-DNA lupus autoantibodies. Clin Immunol Immunopathol (1984) 1.76
The insulin-like growth factor axis: A review of atherosclerosis and restenosis. Circ Res (2000) 1.75
Blood pressure changes in acute cerebral infarction and hemorrhage. Stroke (1997) 1.74
Effects of a positron-emitting vanadium-48 nitinol stent on experimental restenosis in porcine coronary arteries: an injury-response study. Cardiovasc Radiat Med (2001) 1.72
Enhanced coronary vasa vasorum neovascularization in experimental hypercholesterolemia. J Clin Invest (1998) 1.68
Coronary calcium, as determined by electron beam computed tomography, and coronary disease on arteriogram. Effect of patient's sex on diagnosis. Circulation (1995) 1.67
Relationship of human variable region heavy chain germ-line genes to genes encoding anti-DNA autoantibodies. J Immunol (1987) 1.67
A new method for measurement of blood pressure, heart rate, and activity in the mouse by radiotelemetry. J Appl Physiol (1985) (2000) 1.65
Involuntary weight loss in older outpatients: incidence and clinical significance. J Am Geriatr Soc (1995) 1.63
Polymorphisms in human H chain V region genes from the VHIII gene family. J Immunol (1989) 1.62
Synthesis of IgM by cells of NZB and SWR mice and their crosses. J Immunol (1979) 1.62
D-Dimer is an early diagnostic marker of coronary ischemia in patients with chest pain. Am Heart J (2000) 1.57
Detection of heart calcification with electron beam CT: interobserver and intraobserver reliability for scoring quantification. Radiology (1994) 1.55
Leukemia virus activation in chronic allogeneic disease. Proc Natl Acad Sci U S A (1970) 1.55
Genetic studies of autoimmunity and retrovirus expression in crosses of New Zealand black mice I. Xenotropic virus. J Exp Med (1978) 1.55
Utility of magnetic resonance imaging in diagnosing ulnar neuropathy at the elbow. Clin Neurophysiol (2006) 1.54
Multiple serologic reactions and their relationship to clinical activity in systemic lupus erythematosus. Arthritis Rheum (1984) 1.53
Long-term vessel response to a self-expanding coronary stent: a serial volumetric intravascular ultrasound analysis from the ASSURE Trial.A Stent vs. Stent Ultrasound Remodeling Evaluation. J Am Coll Cardiol (2001) 1.52
Coronary artery calcification detected with ultrafast CT as an indication of coronary artery disease. Radiology (1992) 1.51
The adhesive sickle erythrocyte: cause and consequence of abnormal interactions with endothelium, monocytes/macrophages and model membranes. Clin Haematol (1985) 1.51
Normal mice express idiotypes related to autoantibody idiotypes of lupus mice. Proc Natl Acad Sci U S A (1983) 1.50
Immunologic and genetic factors in autoimmune diseases. N Engl J Med (1984) 1.50
Immunochemical similarities between monoclonal antibacterial Waldenstrom's macroglobulins and monoclonal anti-DNA lupus autoantibodies. J Exp Med (1985) 1.49
Murine monoclonal anti-DNA autoantibodies bind to endogenous bacteria. J Immunol (1985) 1.49
Multivariate analysis of factors associated with invasive fungal disease during remission induction therapy for acute myelogenous leukemia. Cancer (1984) 1.49
An algorithm for noninvasive identification of angiographic three-vessel and/or left main coronary artery disease in symptomatic patients on the basis of cardiac risk and electron-beam computed tomographic calcium scores. J Am Coll Cardiol (1999) 1.48
Continuous-scale physical functional performance in healthy older adults: a validation study. Arch Phys Med Rehabil (1996) 1.47
Monoclonal anti-cardiolipin antibodies bind to DNA. Eur J Immunol (1984) 1.47
Chronic allogeneic disease. II. Development of lymphomas. J Exp Med (1970) 1.46
Immunoglobulin heavy chain gene expression in peripheral blood B lymphocytes. J Clin Invest (1992) 1.46
Mendelian segregation of loci controlling xenotropic virus production in NZB crosses. Virology (1977) 1.46
Obesity, body fat distribution, insulin sensitivity and Islet beta-cell function as explanations for metabolic diversity. J Nutr (2001) 1.45
Increased oxidative stress in experimental renovascular hypertension. Hypertension (2001) 1.44
High-frequency representation of a single VH gene in the expressed human B cell repertoire. J Exp Med (1993) 1.44
Coronary angioplasty and intracoronary thrombolysis are of limited efficacy in resolving early intracoronary stent thrombosis. J Am Coll Cardiol (1996) 1.43
Malignant lymphoproliferative diseases: interactions between immunological abnormalities and oncogenic viruses. Annu Rev Med (1968) 1.43
Transmyocardial and percutaneous myocardial revascularization: current and future role in the treatment of coronary artery disease. Mayo Clin Proc (1999) 1.40
Immunodeficiency and the pathogenesis of lymphoma and leukemia. Semin Hematol (1978) 1.40
Effect of endurance exercise training on heart rate variability at rest in healthy young and older men. Am J Cardiol (1998) 1.39
Impact of stent size and indication for stent placement on immediate outcome. Cathet Cardiovasc Diagn (1996) 1.39
Genetic studies of autoimmunity and retrovirus expression in crosses of New Zealand black mice. II. The viral envelope glycoprotein gp70. J Exp Med (1978) 1.39
Disproportionately elevated proinsulin levels reflect the degree of impaired B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab (1998) 1.38
Splenocyte plaque assay for the detection of murine leukemia virus. Proc Soc Exp Biol Med (1975) 1.37
Effect of ischemia on ventricular contractility in patients with coronary artery disease. Angiology (1990) 1.37
Lupus prone (SWR x NZB)F1 mice produce potentially nephritogenic autoantibodies inherited from the normal SWR parent. J Immunol (1985) 1.37
Probabilistic model for prediction of angiographically defined obstructive coronary artery disease using electron beam computed tomography calcium score strata. Circulation (2000) 1.36
Noninvasive definition of anatomic coronary artery disease by ultrafast computed tomographic scanning: a quantitative pathologic comparison study. J Am Coll Cardiol (1992) 1.36
Cardiovascular responses to exercise. Effects of aging and exercise training in healthy men. Circulation (1994) 1.35
Determinants of infarct size in reperfusion therapy for acute myocardial infarction. Circulation (1992) 1.33
Noninvasive measurement of rate of left ventricular relaxation by Doppler echocardiography. Validation with simultaneous cardiac catheterization. Circulation (1993) 1.33
Genetics of expression of xenotropic virus and autoimmunity in NZB mice. Nature (1976) 1.33
Relation of coronary calcium determined by electron beam computed tomography and lumen narrowing determined by autopsy. Am J Cardiol (1994) 1.32
Selective expression of xenotropic virus in congenic HRS/J (hairless) mice. Nature (1977) 1.31
Chronic allogeneic disease. I. Development of glomerulonephritis. J Exp Med (1968) 1.28
Histologic correlates of angiographic chronic total coronary artery occlusions: influence of occlusion duration on neovascular channel patterns and intimal plaque composition. J Am Coll Cardiol (1997) 1.28
Homology of the NH2-terminal amino acid sequences of the heavy and light chains of human monoclonal lupus autoantibodies containing the dominant 16/6 idiotype. J Clin Invest (1985) 1.26
Another look at immunologic surveillance. N Engl J Med (1975) 1.26
Immunohemolytic anemia due to antipenicillin antibodies. Report of a case. N Engl J Med (1966) 1.26
In vitro lymphocyte stimulation by a soluble antigen from malignant melanoma. N Engl J Med (1970) 1.25
Immunosuppression by antibody: localization of site of action. J Immunol (1969) 1.25
Coronary embolization after balloon angioplasty or thrombolytic therapy: an autopsy study of 32 cases. J Am Coll Cardiol (1993) 1.25
Increase of adipose tissue lipoprotein lipase activity with weight loss. J Clin Invest (1981) 1.23
Effect of exercise on insulin action, glucose tolerance, and insulin secretion in aging. Am J Physiol (1990) 1.22
Enhancement of antibody synthesis by 6-mercaptopurine. J Exp Med (1966) 1.22
Role of recombinant ecotropic and polytropic viruses in the development of spontaneous thymic lymphomas in HRS/J mice. J Virol (1984) 1.22
Electron beam computed tomographic coronary calcium score cutpoints and severity of associated angiographic lumen stenosis. J Am Coll Cardiol (1997) 1.21