Published in J Immunol on January 01, 1969
Ro small cytoplasmic ribonucleoproteins are a subclass of La ribonucleoproteins: further characterization of the Ro and La small ribonucleoproteins from uninfected mammalian cells. Mol Cell Biol (1981) 4.41
The Ro small cytoplasmic ribonucleoproteins: identification of the antigenic protein and its binding site on the Ro RNAs. Proc Natl Acad Sci U S A (1984) 3.51
A 52-kD protein is a novel component of the SS-A/Ro antigenic particle. J Exp Med (1988) 2.98
Characterization of a high molecular weight acidic nuclear protein recognized by autoantibodies in sera from patients with polymyositis-scleroderma overlap. J Clin Invest (1981) 2.68
Comparison of the American-European Consensus Group Sjogren's syndrome classification criteria to newly proposed American College of Rheumatology criteria in a large, carefully characterised sicca cohort. Ann Rheum Dis (2013) 2.21
Molecular analysis of the 60-kDa human Ro ribonucleoprotein. Proc Natl Acad Sci U S A (1988) 2.11
Ultraviolet light induces binding of antibodies to selected nuclear antigens on cultured human keratinocytes. J Clin Invest (1984) 2.10
Molecular properties of the Ro/SSA antigen and enzyme-linked immunosorbent assay for quantitation of antibody. J Clin Invest (1984) 1.90
A soluble acidic protein of the cell nucleus which reacts with serum from patients with systemic lupus erythermatosus and Sjögren's syndrome. J Clin Invest (1977) 1.82
Purification and characterization of the Sjögren's syndrome A and B antigens. Clin Exp Immunol (1983) 1.73
Antibodies from patients with connective tissue diseases bind specific subsets of cellular RNA-protein particles. J Clin Invest (1982) 1.66
Molecular cloning, expression, and chromosome 19 localization of a human Ro/SS-A autoantigen. J Clin Invest (1990) 1.64
Identification of antibodies to acidic antigens by counterimmunoelectrophoresis. Ann Rheum Dis (1982) 1.64
Anti-Ro(SSA) positive rheumatoid arthritis (RA): a clinicoserological group of patients with high incidence of D-penicillamine side effects. Ann Rheum Dis (1985) 1.56
Routine immunofluorescence detection of Ro/SS-A autoantibody using HEp-2 cells transfected with human 60 kDa Ro/SS-A. J Clin Pathol (1999) 1.48
Characterisation of anticytoplasmic antibodies and their clinical associations. Ann Rheum Dis (1995) 1.46
Heterogeneity of the Ro/SSA antigen. Different molecular forms in lymphocytes and red blood cells. J Clin Invest (1989) 1.41
TRIM68 negatively regulates IFN-β production by degrading TRK fused gene, a novel driver of IFN-β downstream of anti-viral detection systems. PLoS One (2014) 1.39
Protein heterogeneity in the human Ro/SSA ribonucleoproteins. The 52- and 60-kD Ro/SSA autoantigens are encoded by separate genes. J Clin Invest (1991) 1.38
A subset of hY RNAs is associated with erythrocyte Ro ribonucleoproteins. EMBO J (1990) 1.34
Molecular characterization of human Ro/SS-A antigen. Amino terminal sequence of the protein moiety of human Ro/SS-A antigen and immunological activity of a corresponding synthetic peptide. J Clin Invest (1988) 1.32
Current perspectives on serological reactions in SLE patients. Clin Exp Immunol (1981) 1.28
Early disease onset is predicted by a higher genetic risk for lupus and is associated with a more severe phenotype in lupus patients. Ann Rheum Dis (2010) 1.26
The mapping of the human 52-kD Ro/SSA autoantigen gene to human chromosome 11, and its polymorphisms. Am J Hum Genet (1993) 1.24
A human Ro/SS-A autoantigen is the homologue of calreticulin and is highly homologous with onchocercal RAL-1 antigen and an aplysia "memory molecule". J Clin Invest (1990) 1.17
Antinuclear antibodies and their detection methods in diagnosis of connective tissue diseases: a journey revisited. Diagn Pathol (2009) 1.14
Antibodies to nRNP, Sm, Ro(SSA) and La(SSB) detected by ELISA: their specificity and inter-relations in connective tissue disease sera. Clin Exp Immunol (1985) 1.13
Implications of anti-Ro/Sjögren's syndrome A antigen autoantibody in normal sera for autoimmunity. J Clin Invest (1987) 1.10
Autoimmune response to the Ro/SSA particle is directed to the human antigen. Clin Exp Immunol (1989) 1.09
Lupus autoantibodies to native DNA cross-react with the A and D SnRNP polypeptides. J Clin Invest (1994) 1.07
IgG antibodies from patients with primary Sjögren's syndrome and systemic lupus erythematosus recognize different epitopes in 60-kD SSA/Ro protein. Clin Exp Immunol (1992) 1.07
Autoantibodies to RNA polymerase II are common in systemic lupus erythematosus and overlap syndrome. Specific recognition of the phosphorylated (IIO) form by a subset of human sera. J Clin Invest (1994) 1.07
Circulating immune complexes in systemic lupus erythematosus. Clin Exp Immunol (1977) 1.07
Renal involvement in primary antiphospholipid syndrome: retrospective analysis of 160 patients. Clin J Am Soc Nephrol (2010) 1.05
Autoimmunity to the M(r) 32,000 subunit of replication protein A in breast cancer. Clin Cancer Res (2002) 1.05
ER Stress Proteins in Autoimmune and Inflammatory Diseases. Front Immunol (2012) 1.04
Emerging roles for the Ro 60-kDa autoantigen in noncoding RNA metabolism. Wiley Interdiscip Rev RNA (2011) 1.02
Immune responses to Ro60 and its peptides in mice. I. The nature of the immunogen and endogenous autoantigen determine the specificities of the induced autoantibodies. J Exp Med (1999) 1.02
The Ro/SSA autoantigen as an immunogen. Some anti-Ro/SSA antibody binds IgG. J Exp Med (1986) 1.02
Clinical and autoantibody correlations in Orientals with systemic lupus erythematosus. Ann Rheum Dis (1988) 1.01
Differential isotype recognition of two centromere associated polypeptides by immunoblotting in connective tissue disease. Clin Exp Immunol (1988) 1.01
Genetic deficiency of C4, C2 or C1q and lupus syndromes. Association with anti-Ro (SS-A) antibodies. Clin Exp Immunol (1985) 1.00
Fetal complete heart block. Br Heart J (1988) 1.00
ROP-1, an RNA quality-control pathway component, affects Caenorhabditis elegans dauer formation. Proc Natl Acad Sci U S A (2000) 0.98
Antibody penetration of viable human cells. I. Increased penetration of human lymphocytes by anti-RNP IgG. Clin Exp Immunol (1991) 0.97
Anti-Ro(SSA) autoantibodies are associated with T cell receptor beta genes in systemic lupus erythematosus patients. J Clin Invest (1990) 0.96
Characterisation of centromere (kinetochore) antigen reactive with sera of patients with a scleroderma variant (CREST syndrome). Ann Rheum Dis (1984) 0.96
Sera from patients with rheumatic diseases recognize different epitope regions on the 52-kD Ro/SS-A protein. Clin Exp Immunol (1993) 0.96
Anti-Ro antibody and cutaneous vasculitis in systemic lupus erythematosus. Clin Rheumatol (2008) 0.95
Nuclear deposits of immunoglobulins in skin of patients with systemic lupus erythematosus. Clin Exp Immunol (1977) 0.95
HLA-DQ gene complementation and other histocompatibility relationships in man with the anti-Ro/SSA autoantibody response of systemic lupus erythematosus. J Clin Invest (1990) 0.93
The Ro60 autoantigen binds endogenous retroelements and regulates inflammatory gene expression. Science (2015) 0.92
HLA-DR antigens in systemic lupus erythematosus: association with specificity of autoantibody responses to nuclear antigens. Ann Rheum Dis (1987) 0.90
Practical evaluation of methods for detection and specificity of autoantibodies to extractable nuclear antigens. Clin Diagn Lab Immunol (2004) 0.88
Calreticulin synthetic peptide analogues: anti-peptide antibodies in autoimmune rheumatic diseases. Clin Exp Immunol (1993) 0.87
Autoantibodies to mitochondrial and centromere antigens in primary biliary cirrhosis and systemic sclerosis. Clin Exp Immunol (1990) 0.87
Clinical and pathological roles of Ro/SSA autoantibody system. Clin Dev Immunol (2012) 0.86
Autoantibodies to human nuclear antigen(s)-HNA-in connective tissue diseases and other disorders. Clin Exp Immunol (1986) 0.86
Male-only systemic lupus. J Rheumatol (2010) 0.86
Autoantibodies in the sicca syndrome (primary Sjögren's syndrome). Ann Rheum Dis (1984) 0.85
Basis for defective proliferation of peripheral blood T cells to anti-CD2 antibodies in primary Sjögren's syndrome. J Clin Invest (1990) 0.85
Autoantigen TRIM21/Ro52 as a Possible Target for Treatment of Systemic Lupus Erythematosus. Int J Rheumatol (2012) 0.85
Relation of sensory peripheral neuropathy in Sjögren syndrome to anti-Ro/SSA. J Clin Rheumatol (2012) 0.85
Type C RNA virus-specific antibody in human systemic lupus erythematosus demonstrated by enzymoimmunoassay. Proc Natl Acad Sci U S A (1978) 0.85
Diversity of autoantibodies in avian scleroderma. An inherited fibrotic disease of White Leghorn chickens. J Clin Invest (1984) 0.84
Hashimoto's thyroiditis and polyarthritis: a possible subset of seronegative polyarthritis. Ann Rheum Dis (1984) 0.83
Epitope mapping of the 52-kD Ro/SSA autoantigen. Clin Exp Immunol (1994) 0.83
Non-coding Y RNAs as tethers and gates: Insights from bacteria. RNA Biol (2013) 0.82
Relationship of precipitating antibodies to soluble cellular antigens and histologically defined renal lesions in systemic lupus erythematosus. Ann Rheum Dis (1983) 0.81
Characterization of a distinct nuclear acidic protein antigen (MA) and clinical findings in systemic lupus erythematosus patients with MA antibodies. J Clin Invest (1979) 0.81
A human monoclonal autoantibody to a nucleolar structure. Clin Exp Immunol (1992) 0.80
Expression and DNA binding of the human 52 kDa Ro/SSA autoantigen. Biochem J (1995) 0.79
Prolidase deficiency breaks tolerance to lupus-associated antigens. Int J Rheum Dis (2013) 0.79
Serum immune complexes in systemic sclerosis: relationship with precipitating nuclear antibodies. Ann Rheum Dis (1985) 0.79
Further characterization of the autoantibody response of Palmerston North mice. J Clin Immunol (1999) 0.78
Anti-Ro (SSA)/La (SSB) antibodies and Sjögren's syndrome. Clin Rheumatol (1990) 0.78
Gold nephropathy: serologic data suggesting an immune complex disease. Clin Exp Immunol (1976) 0.77
Systemic diseases and the detection of antinuclear and anticytoplasmic antibodies. An historical review. Clin Rheumatol (1987) 0.77
Higher incidences of anti-SS-A/Ro and anti-SS-B/La autoantibodies in Japanese patients with autoimmune disorders--studies of antigens and antibodies using the immunoblotting method. Arch Dermatol Res (1989) 0.76
Autoantibodies to the RoRNP particles. Clin Exp Immunol (1995) 0.76
Recent advances in the immunopathogenesis of systemic lupus erythematosus. West J Med (1975) 0.75
Studies with human leukocyte lysosomes. Evidence for antilysosome antibodies in lupus erythematosus and for the presence of lysosomal antigen in inflammatory diseases. J Clin Invest (1975) 0.75
HLA antigens in Italian patients with primary Sjögren's syndrome. Ann Rheum Dis (1986) 0.75
Association between Secondary and Primary Sjögren's Syndrome in a Large Collection of Lupus Families. Autoimmune Dis (2015) 0.75
Antibodies to Mi-1 in SLE: relationship to other precipitins and reaction with bovine immunoglobulin. Clin Exp Immunol (1983) 0.75
More than one way to TRIM a capsid. Proc Natl Acad Sci U S A (2012) 0.75
Next-Generation Autoantibody Testing by Combination of Screening and Confirmation-the CytoBead® Technology. Clin Rev Allergy Immunol (2017) 0.75
The DNA sequence and comparative analysis of human chromosome 20. Nature (2002) 7.40
Secretory immunoglobulins. Adv Immunol (1968) 7.00
STUDIES IN CONGESTIVE HEART FAILURE. XXIIII. A CRITICAL STUDY OF METHODS FOR DETERMINING THE CARDIAC OUTPUT IN PATIENTS WITH CARDIAC DISEASE. J Clin Invest (1933) 6.31
The DNA sequence and analysis of human chromosome 6. Nature (2003) 4.75
STUDIES IN CONGESTIVE HEART FAILURE: III. The Buffering Power of the Blood and Tissues. J Clin Invest (1930) 4.52
Systemic tolerance and secretory immunity after oral immunization. J Exp Med (1980) 3.79
Autoimmune-associated congenital heart block: demographics, mortality, morbidity and recurrence rates obtained from a national neonatal lupus registry. J Am Coll Cardiol (1998) 3.68
Purification and partial characterization of a nucleolar scleroderma antigen (Mr = 34,000; pI, 8.5) rich in NG,NG-dimethylarginine. J Biol Chem (1985) 3.60
Characterization of a soluble nuclear ribonucleoprotein antigen reactive with SLE sera. J Immunol (1971) 3.59
Structure and function of immunoglobulin A. Prog Allergy (1972) 3.14
The human secretory immunoglobulin system: immunohistoligical localization of gamma A, secretory "piece," and lactoferrin in normal human tissues. J Exp Med (1969) 3.08
Physical association of two nuclear antigens and mutual occurrence of their antibodies: the relationship of the SM and RNAprotein (MO) systems in SLE sera. J Immunol (1973) 3.07
Heterogeneity of RNA protein antigens reactive with sera of patients with systemic lupus erythematosus. Description of a cytoplasmic nonribosomal antigen. Arthritis Rheum (1974) 2.99
Use of glutaraldehyde as a coupling agent for proteins and peptides. Methods Enzymol (1980) 2.73
Anti-Ro (SS-A) and anti-La (SS-B) in patients with Sjögren's syndrome. Arthritis Rheum (1986) 2.39
The Hillsborough tragedy. BMJ (1991) 2.36
Amino acid substitution and the antigenicity of globular proteins. Adv Immunol (1975) 2.32
A Low Molecular Weight Immunoglobulin Antigenically Related to 19 S IgM. J Clin Invest (1967) 2.31
Serological findings in patients with "ANA-negative" systemic lupus erythematosus. Medicine (Baltimore) (1981) 2.27
Serologic and HLA associations in subacute cutaneous lupus erythematosus, a clinical subset of lupus erythematosus. Ann Intern Med (1982) 2.26
Heterogeneity of precipitating antibodies in polymyositis and dermatomyositis. Characterization of the Jo-1 antibody system. Arthritis Rheum (1980) 2.23
Immunoglobulin M: pentameric Fcmu fragments released by trypsin at higher temperatures. Proc Natl Acad Sci U S A (1970) 2.18
Oral tolerance. Transplantation (1980) 2.17
Correlation of a precipitin reaction to an RNAprotein antigen and a low prevalence of nephritis in patients with systemic lupus erythematosus. N Engl J Med (1972) 2.12
Anti-DNA antibody idiotypes in systemic lupus erythematosus. Lancet (1984) 2.08
Activation of MHC class I, II, and CD40 gene expression by histone deacetylase inhibitors. J Immunol (2000) 2.07
Suppression of the immune response by alpha-fetoprotein on the primary and secondary antibody response. J Exp Med (1975) 2.03
HIV gp120 receptors on human dendritic cells. Blood (2001) 2.03
Meticillin-resistant Staphylococcus aureus carriage among district nurse patients and medical admissions in a UK district. J Hosp Infect (2007) 1.98
Molecular properties of the Ro/SSA antigen and enzyme-linked immunosorbent assay for quantitation of antibody. J Clin Invest (1984) 1.90
In vitro studies of inflammatory bowel disease. Surface receptors of the mononuclear cell required to lyse allogeneic colonic epithelial cells. Gastroenterology (1976) 1.83
Secretory gamma-A in normal urine. J Clin Invest (1968) 1.74
Evidence for complement activation via the alternate pathway in skin diseases, I. Herpes gestationis, systemic lupus erythematosus, and bullous pemphigoid. J Clin Invest (1973) 1.73
The life span of IgA plasma cells from the mouse intestine. J Exp Med (1973) 1.69
Molecular cloning, expression, and chromosome 19 localization of a human Ro/SS-A autoantigen. J Clin Invest (1990) 1.64
The association between Mi-2 antibodies and dermatomyositis. Arthritis Rheum (1985) 1.62
Studies on human intestinal immunoglobulin A. Gastroenterology (1971) 1.62
Human immunoglobulin A: production of an Fc fragment by an enteric microbial proteolytic enzyme. J Immunol (1973) 1.60
Clinical and serological differences between systemic lupus erythematosus patients with antibodies to Ro versus patients with antibodies to Ro and La. J Clin Invest (1982) 1.58
Anti-threonyl-tRNA synthetase, a second myositis-related autoantibody. J Exp Med (1984) 1.54
Autoantibodies of neonatal lupus erythematosus. J Invest Dermatol (1994) 1.53
The autoantibody response to Ro/SSA in cutaneous lupus erythematosus. Arch Dermatol (1994) 1.53
Significance of histologic patterns of glomerular injury upon long-term prognosis in severe lupus glomerulonephritis. Kidney Int (2001) 1.52
The clinical significance of autoantibodies to a soluble cytoplasmic antigen in systemic lupus erythematosus and other connective tissue diseases. J Rheumatol (1979) 1.51
The presence of masked antiribosomal P autoantibodies in healthy children. Arthritis Rheum (1998) 1.51
Factors predictive of outcome in severe lupus nephritis. Lupus Nephritis Collaborative Study Group. Am J Kidney Dis (2000) 1.50
A distinctive autoantibody profile in black female patients with lupus nephritis. Arthritis Rheum (1993) 1.50
Gene interaction at HLA-DQ enhances autoantibody production in primary Sjögren's syndrome. Science (1986) 1.50
Twenty percent of biopsy specimens from sun-exposed skin of normal young adults demonstrate positive immunofluorescence. Arch Dermatol (1991) 1.47
Two Ro (SS-A) autoantibody responses in systemic lupus erythematosus. Correlation of HLA-DR/DQ specificities with quantitative expression of Ro (SS-A) autoantibody. Arthritis Rheum (1988) 1.47
Structure and function of mucosal antibodies. Annu Rev Med (1970) 1.46
Male ritual circumcision resulting in acute renal failure. BMJ (1994) 1.45
Human immunoglobulin A. N Engl J Med (1968) 1.44
Lymphocyte cytotoxicity and inhibition studied with autologous liver cells: observations in chronic active liver disease and the primary biliary cirrhosis syndrome. Gastroenterology (1976) 1.43
Lung bioavailability of generic and innovator salbutamol metered dose inhalers. Thorax (1996) 1.43
Host defense mechanisms at mucosal surfaces. Annu Rev Microbiol (1981) 1.42
Heterogeneity of the Ro/SSA antigen. Different molecular forms in lymphocytes and red blood cells. J Clin Invest (1989) 1.41
The importance of being K-Ras. Cell Signal (2000) 1.40
Familial aggregation and linkage analysis of autoantibody traits in pedigrees multiplex for systemic lupus erythematosus. Genes Immun (2006) 1.39
Deficiency of immunoglobulin A in intestinal disease. Gastroenterology (1968) 1.37
Autoantibodies to the ribosomal P proteins react with a plasma membrane-related target on human cells. J Clin Invest (1992) 1.37
A model for disease heterogeneity in systemic lupus erythematosus. Relationships between histocompatibility antigens, autoantibodies, and lymphopenia or renal disease. Arthritis Rheum (1989) 1.37
Mutation of putative branchpoint consensus sequences in plant introns reduces splicing efficiency. Plant J (1996) 1.36
Problems in differentiating SLE and mixed connective-tissue disease. N Engl J Med (1976) 1.36
Reference sera for antinuclear antibodies. I. Antibodies to native DNA, Sm, nuclear RNP, and SS-B/La. Arthritis Rheum (1982) 1.33
Characterization of the serum and secretory immune systems of the cow and sheep. J Immunol (1969) 1.33
Antibodies to human albumin in cirrhotic sera. J Clin Invest (1974) 1.32
Salivary gland immunoglobulin and rheumatoid factor synthesis in Sjögren's syndrome. Natural history and response to treatment. Am J Med (1972) 1.32
Association between CYP1A1 genotype, mRNA expression and enzymatic activity in humans. Pharmacogenetics (1994) 1.31
Description of a serological reaction characteristic of polymyositis. Clin Immunol Immunopathol (1976) 1.30
Antibodies to a nuclear/nucleolar antigen in patients with polymyositis overlap syndromes. J Clin Immunol (1984) 1.30
Current perspectives on serological reactions in SLE patients. Clin Exp Immunol (1981) 1.28
The human female reproductive tract: immunohistological localization of gamma A, gamma G, gamma M, secretory "piece," and lactoferrin. Am J Obstet Gynecol (1970) 1.28
Deposition of antibodies to a soluble cytoplasmic antigen in the kidneys of patients with systemic lupus erythematosus. Arthritis Rheum (1979) 1.26
Demonstration of antimyelin antibodies by immunofluorescence in Guillain-Barré syndrome. Clin Exp Immunol (1971) 1.26
Lymphoid interstitial pneumonia with monoclonal gammopathy. Am Rev Respir Dis (1968) 1.25
Idiotypic cross-reactivity between antibodies of different specificities. J Exp Med (1978) 1.24
Mechanisms of immune regulation at mucosal surfaces. Rev Infect Dis (1983) 1.22
Monoclonal antibody to the interferon-inducible protein Leu-13 triggers aggregation and inhibits proliferation of leukemic B cells. Blood (1990) 1.22
Natural antibodies of human serum, saliva, and urine reactive with Escherichia coli. Proc Soc Exp Biol Med (1968) 1.22
Significance of the Ro antigen system. J Clin Immunol (1986) 1.22
Production of a runting syndrome and selective A deficiency in mice by the administration of anti-heavy chain antisera. J Exp Med (1973) 1.22
Immunological activity of cytochrome c. 3. Enhancement of antibody detection and immune response initiation by cytochrome c polymers. J Biol Chem (1970) 1.20
A mammalian tRNAHis-containing antigen is recognized by the polymyositis-specific antibody anti-Jo-1. Nucleic Acids Res (1983) 1.19
Anti-Ro(SS-A) autoantibodies in central nervous system disease associated with Sjögren's syndrome (CNS-SS): clinical, neuroimaging, and angiographic correlates. Neurology (1994) 1.19
Glucose synthesis in tritiated water. Eur J Biochem (1974) 1.19
Quantitation of precipitating antibodies to certain soluble nuclear antigens in SLE. Arthritis Rheum (1977) 1.18
Immune parameters in athletes before and after strenuous exercise. J Clin Immunol (1982) 1.17
The reactions of antibodies with hemeprotein antgens. The measurement of reaction kinetics and stoichiometry by fluorescence quenching. J Biol Chem (1969) 1.16
Methodology for constructing guidance. J Clin Pathol (2005) 1.15
Immunological activity of cytochrome c. I. Precipitating antibodies to monomeric vertebrate cytochromes c. J Biol Chem (1970) 1.14
Studies on extracellular proteases of Streptococcus sanguis. Purification and characterization of a human IgA1 specific protease. Biochim Biophys Acta (1978) 1.14
In vitro antitumor activity of the novel marine agent, ecteinascidin-743 (ET-743, NSC-648766) against human tumors explanted from patients. Ann Oncol (1998) 1.14
Antibodies to cytoplasmic antigens in lupus erythematosus. Serologic marker for systemic disease. Arthritis Rheum (1977) 1.13
hTERT mRNA expression correlates with telomerase activity in human breast cancer. Eur J Surg Oncol (2003) 1.13
The development of speech perception in children using cochlear implants: effects of etiologic factors and delayed milestones. Am J Otol (2000) 1.12
Autoantibodies to the Ro/SSA antigen are conformation dependent. I: Anti-60 kD antibodies are mainly directed to the native protein; anti-52 kD antibodies are mainly directed to the denatured protein. Autoimmunity (1992) 1.12
Heterogeneity of the Ro/SSA antigen and autoanti-Ro/SSA response: evidence of the four antigenically distinct forms. Clin Exp Immunol (1990) 1.11
Antinuclear and anti-single-stranded DNA antibodies in morphea and generalized morphea. Arch Dermatol (1987) 1.11
Studies on the chymotrypsin C and papain fragments of human immunoglobulin M. Biochemistry (1969) 1.11