Published in J Exp Med on June 01, 1970
Immunoregulatory circuits among T-cell sets. II. Physiologic role of feedback inhibition in vivo: absence in NZB mice. J Exp Med (1978) 5.48
Strain differences in the immune responses of mice. 3. A raised tolerance threshold in NZB thymus cells. Immunology (1971) 1.57
Interleukin 6 promotes murine lupus in NZB/NZW F1 mice. J Clin Invest (1994) 1.56
Loss of suppressor T cells in adult NZB/NZW mice. J Exp Med (1976) 1.52
A defect of B-lymphocyte transport of aggregated HGG into germinal centres in NZB and NZB x NZW F 1 hybrid mice. Clin Exp Immunol (1972) 1.38
CBA/N X-linked B-cell defect prevents NZB B-cell hyperactivity in F1 mice. J Exp Med (1979) 1.12
T and B lymphocytes in New Zealand black mice. An analysis of the theta, TL and MBLA markers. Clin Exp Immunol (1972) 1.03
Monoclonal macroglobulinemia in NZB-NZW F1 mice. J Exp Med (1973) 1.02
Studies of defective tolerance induction in NZB mice. Evidence for a marrow pre-T cell defect. J Exp Med (1982) 0.91
The long-term antibody response of New Zealand Black mice to sheep red blood cells. Immunology (1974) 0.90
Defective B cell tolerance in adult (NZB X MZW)F1 mice. J Exp Med (1980) 0.89
Age-related decline in the antibody response to E. coli lipopolysaccharide in New Zealand Black mice. Immunology (1975) 0.88
Alteration in DNA synthetic response of thymocytes from NZB mice of different ages. Proc Natl Acad Sci U S A (1973) 0.85
The immune response in NZB mice of different ages to thymus-dependent and thymus-independent phosphorylcholine antigens. Immunology (1978) 0.85
Normal tolerance characteristics of the antibody-forming cell precursors of the NZB mouse. Clin Exp Immunol (1973) 0.82
In vitro studies on the phagocytosis of Staphylococcus aureus by peritoneal macrophages of New Zealand mice. Immunology (1973) 0.79
T-cell tolerance induction is normal in the (NZB x NZW)F1 murine model of systemic lupus erythematosus. Immunology (2000) 0.79
Immunosuppression by immunoglobulin deaggregation is not effective in reducing the anti-xenogeneic immunoglobulin response: experimental and clinical studies. Br J Cancer (1989) 0.75
Thymus-marrow cell combinations. Synergism in antibody production. Proc Soc Exp Biol Med (1966) 10.03
Cell to cell interaction in the immune response. I. Hemolysin-forming cells in neonatally thymectomized mice reconstituted with thymus or thoracic duct lymphocytes. J Exp Med (1968) 9.67
Preparation of formalinized erythrocytes. Proc Soc Exp Biol Med (1960) 4.13
Further implication of murine leukemia-like virs in the disorders of NZB mice. J Exp Med (1969) 3.87
Strain differences in the immune response of mice. I. The neonatal response to sheep red cells. Immunology (1968) 2.98
Studies of proteins and antibodies by specific hemagglutination and hemolysis of proteinconjugated erythrocytes. Int Arch Allergy Appl Immunol (1958) 2.98
Relative inability to induce tolerance in adult NZB and NZB-NZW F1 mice. J Exp Med (1969) 2.78
Bone marrow as a source of cells in reactions of cellular hypersensitivity. I. Passive transfer of tuberculin sensitivity in syngeneic systems. J Exp Med (1968) 2.77
The appearance of immunological competence at an early age in New Zealand black mice. Clin Exp Immunol (1968) 2.73
The pathogenesis of autoimmunity in New Zealand mice, I. Induction of antinucleic acid antibodies by polyinosinic-polycytidylic acid. Proc Natl Acad Sci U S A (1969) 2.31
Role of the thymus in tolerance. I. Tolerance to bovine gamma globulin in thymectomized, irradiated rats grafted with thymus from tolerant donors. J Exp Med (1965) 2.29
Immune paralysis of thymus cells by bovine serum albumin. Nature (1968) 2.20
Genetic investigations of autoimmune disease in mice. Nature (1965) 2.18
THE THYMUS AND AUTOIMMUNE DISEASE. Lancet (1963) 2.14
THYMECTOMY: PROLONGATION OF IMMUNOLOGICAL TOLERANCE IN THE ADULT MOUSE. Science (1963) 2.06
Comparison of the immune responsiveness of NZB and NZB X NZW F1 hybrid mice with that of other strains of mice. J Exp Med (1969) 1.87
Response of NZB mice to foreign antigen and development of autoimmune disease. J Reticuloendothel Soc (1969) 1.75
Immune response to a soluble protein antigen in NZB mice. Nature (1968) 1.51
Strain differences in the immune response of mice. II. Responses by neonatal cells in irradiated adult hosts. Immunology (1968) 1.45
Rapid loss of tolerance induced in weanling NZB and B-W F1 mice. Science (1969) 1.16
Adjuvanticity of lactic dehydrogenase virus: influence virus infection on the establishment of immunologic tolerance to a protein antigen in adult mice. J Immunol (1967) 1.10
Regeneration of thymus grafts. II. Effects on immunological capacity. Clin Exp Immunol (1966) 1.08
Tolerance to polyinosinic-polycytidylic acid in NZB-NZW mice. Science (1970) 1.03
THYMUS AND X-RADIATION IN THE TERMINATION OF ACQUIRED IMMUNOLOGICAL TOLERANCE IN THE ADULT MOUSE. Nature (1964) 0.99
Normal induction and maintenance of tolerance in (NZBxNZW) F1 mice. Clin Exp Immunol (1969) 0.89
The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum (1982) 67.54
Classification criteria for Sjögren's syndrome: a revised version of the European criteria proposed by the American-European Consensus Group. Ann Rheum Dis (2002) 20.48
The fatigue severity scale. Application to patients with multiple sclerosis and systemic lupus erythematosus. Arch Neurol (1989) 13.32
Measurement of serum DNA-binding activity in systemic lupus erythematosus. N Engl J Med (1969) 6.16
Ly-1 B cells: functionally distinct lymphocytes that secrete IgM autoantibodies. Proc Natl Acad Sci U S A (1984) 5.15
Effect of castration and sex hormone treatment on survival, anti-nucleic acid antibodies, and glomerulonephritis in NZB/NZW F1 mice. J Exp Med (1978) 4.28
Differentiation and characterization of autoantibodies and their antigens in Sjögren's syndrome. Arthritis Rheum (1976) 4.02
Therapy of lupus nephritis. Controlled trial of prednisone and cytotoxic drugs. N Engl J Med (1986) 4.01
The pathogenesis of autoimmunity in New Zealand black mice. Curr Top Microbiol Immunol (1974) 3.98
The histopathology of Sjögren's syndrome in labial salivary gland biopsies. Oral Surg Oral Med Oral Pathol (1974) 3.82
Assignment of direct and facilitated hemolytic plaques in mice to specific immunoglobulin classes. J Immunol (1968) 3.81
X-linked B-lymphocyte immune defect in CBA/HN mice. I. Studies of the function and composition of spleen cells. J Exp Med (1975) 3.70
Sex hormones, immune responses, and autoimmune diseases. Mechanisms of sex hormone action. Am J Pathol (1985) 3.31
Immunoregulatory aberrations in systemic lupus erythematosus. J Immunol (1978) 3.07
Cytokine gene expression after in vivo primary immunization with goat antibody to mouse IgD antibody. J Immunol (1991) 3.04
X-linked B-lymphocyte immune defect in CBA/N mice. II. Studies of the mechanisms underlying the immune defect. J Exp Med (1975) 3.03
The genetics of the immune response to a synthetic double-stranded RNA in a mutant CBA mouse strain. J Immunol (1973) 3.00
Failure of autologous mixed lymphocyte reactions between T and non-T cells in patients with systemic lupus erythematosus. Proc Natl Acad Sci U S A (1978) 2.94
Extrasalivary lymphoid abnormalities in Sjögren's syndrome (reticulum cell sarcoma, "pseudolymphoma," macroglobulinemia). Am J Med (1967) 2.92
Xerostomia in Sjögren's syndrome. Evaluation by sequential salivary scintigraphy. JAMA (1971) 2.89
Effects of thymectomy or androgen administration upon the autoimmune disease of MRL/Mp-lpr/lpr mice. J Immunol (1980) 2.89
Decline in suppressor T cell function with age in female NZB mice. J Immunol (1974) 2.79
Relative inability to induce tolerance in adult NZB and NZB-NZW F1 mice. J Exp Med (1969) 2.78
Combination therapy with pulse cyclophosphamide plus pulse methylprednisolone improves long-term renal outcome without adding toxicity in patients with lupus nephritis. Ann Intern Med (2001) 2.77
Impaired Lymphocyte Transformation and Delayed Hypersensitivity in Sjögren's Syndrome. J Clin Invest (1967) 2.77
Detection of tumor necrosis factor alpha but not tumor necrosis factor beta in rheumatoid arthritis synovial fluid and serum. Arthritis Rheum (1988) 2.77
Systemic autoimmune disease arises from polyclonal B cell activation. J Exp Med (1987) 2.71
Immunologic and viral factors in the pathogenesis of systemic lupus erythematosus. Arthritis Rheum (1971) 2.66
Disordered immunologic regulation and autoimmunity. Transplant Rev (1976) 2.62
Deficient interleukin 2 activity in MRL/Mp and C57BL/6J mice bearing the lpr gene. J Exp Med (1981) 2.46
Loss with age in NZB-W mice of thymic suppressor cells in the graft-vs-host reaction. J Immunol (1974) 2.45
Fractionation of splenic antibody-forming cells on glass bead columns. J Immunol (1967) 2.41
Controlled trial of pulse methylprednisolone versus two regimens of pulse cyclophosphamide in severe lupus nephritis. Lancet (1992) 2.38
Selective loss of suppressor cell function in New Zealand mice induced by NTA. J Immunol (1977) 2.38
B cells expressing CD5 are increased in Sjögren's syndrome. Arthritis Rheum (1988) 2.37
Androgenic hormones modulate autoantibody responses and improve survival in murine lupus. J Clin Invest (1977) 2.33
The pathogenesis of autoimmunity in New Zealand mice, I. Induction of antinucleic acid antibodies by polyinosinic-polycytidylic acid. Proc Natl Acad Sci U S A (1969) 2.31
Studies of immune functions of patients with systemic lupus erythematosus. I. Dysfunction of suppressor T-cell activity related to impaired generation of, rather than response to, suppressor cells. Arthritis Rheum (1979) 2.28
Methylprednisolone and cyclophosphamide, alone or in combination, in patients with lupus nephritis. A randomized, controlled trial. Ann Intern Med (1996) 2.17
Synergy among lymphoid cells mediating the graft-versus-host response. I. Synergy in graft-versus-host reactions produced by cells from NZB-Bl mice. J Exp Med (1970) 2.15
DNA-binding assay for detection of anti-DNA antibodies in NZB-NZW F1 mice. J Immunol (1969) 2.13
B-lymphocyte alloantigens associated with systemic lupus erythematosus. N Engl J Med (1978) 2.11
Alterations in immunoregulatory T cell subsets in active systemic lupus erythematosus. J Clin Invest (1980) 2.06
Defective EBV-specific suppressor T-cell function in rheumatoid arthritis. N Engl J Med (1981) 2.05
Increased spontaneous activity of antibody-forming cells in the peripheral blood of patients with active SLE. Arthritis Rheum (1977) 2.03
beta-Estradiol reduces natural killer cells in mice. J Immunol (1978) 2.02
The spectrum of benign to malignant lymphoproliferation in Sjögren's syndrome. Clin Exp Immunol (1972) 2.01
Filter radioimmunoassay for antibodies to reovirus RNA in systemic lupus erythematosus. Arthritis Rheum (1974) 1.92
Mapping of a gene causing familial Mediterranean fever to the short arm of chromosome 16. N Engl J Med (1992) 1.90
Incidence of infection in systemic lupus erythematosus. Arthritis Rheum (1974) 1.89
Interleukin 2 deficiency is a common feature of autoimmune mice. J Immunol (1981) 1.89
Establishment and characterization of a murine hybridoma secreting monoclonal anti-DNA autoantibody. J Immunol (1980) 1.88
Studies of immune functions of patients with systemic lupus erythematosus. Complement-dependent immunoglobulin M anti-thymus-derived cell antibodies preferentially inactivate suppressor cells. J Clin Invest (1979) 1.87
Effect of murine cytomegalovirus on the in vitro responses of T and B cells to mitogens. J Immunol (1976) 1.84
Interleukin 2 deficiencies in rheumatoid arthritis and systemic lupus erythematosus. Clin Immunol Immunopathol (1984) 1.81
Immunological regulation of spontaneous antibodies to DNA and RNA. II. Sequential switch from IgM to IgG in NZB/NZW F1 mice. Immunology (1977) 1.80
The neuropathy of Sjögren's syndrome. Trigeminal nerve involvement. Ann Intern Med (1969) 1.79
The cellular and genetic basis of murine lupus. Immunol Rev (1981) 1.75
The clearance and localization of nucleic acids by New Zealand and normal mice. Clin Exp Immunol (1972) 1.74
Renal tubular acidosis, glomerulonephritis and immunologic factors in Sjögren's syndrome. Arthritis Rheum (1968) 1.72
The oral component of Sjögren's syndrome. Oral Surg Oral Med Oral Pathol (1975) 1.70
Cyclophosphamide in lupus nephritis: a controlled trial. Ann Intern Med (1971) 1.70
The pathogenesis of autoimmunity in New Zealand mice. 3. Factors influencing the formation of anti-nucleic acid antibodies. Immunology (1971) 1.68
Hematologic aspects of systemic lupus erythematosus. Current concepts. Ann Intern Med (1977) 1.68
Advances in the diagnosis and concept of Sjögren's syndrome (autoimmune exocrinopathy). Bull Rheum Dis (1980) 1.64
Abnormally elevated frequency of Epstein-Barr virus-infected B cells in the blood of patients with rheumatoid arthritis. J Clin Invest (1984) 1.63
T and B lymphocytes in peripheral blood and tissue lesions in Sjögren's syndrome. J Clin Invest (1974) 1.63
Autoimmunity--a perspective. Annu Rev Immunol (1983) 1.62
Interleukin-2 in rheumatoid arthritis: production of and response to interleukin-2 in rheumatoid synovial fluid, synovial tissue and peripheral blood. Clin Exp Immunol (1985) 1.61
NIH conference. Rheumatoid arthritis: evolving concepts of pathogenesis and treatment. Ann Intern Med (1984) 1.61
Mechanism of allograft rejection in New Zealand mice. I. Cell synergy and its age-dependent loss. J Immunol (1973) 1.59
NIH conference. Systemic lupus erythematosus: evolving concepts. Ann Intern Med (1979) 1.59
Dietary enrichment with the polyunsaturated fatty acid eicosapentaenoic acid prevents proteinuria and prolongs survival in NZB x NZW F1 mice. J Clin Invest (1981) 1.58
The natural history and immunopathology of outbred athymic (nude) mice. Clin Immunol Immunopathol (1975) 1.57
SLE-like autoantibodies and Sjögren's syndrome-like lymphoproliferation in TGF-beta knockout mice. J Immunol (1995) 1.57
Evidence that the malignant lymphoma of Sjögren's syndrome is a monoclonal B-cell neoplasm. N Engl J Med (1978) 1.54
Response of NZB and NZB-NZW spleen cells to mitogenic agents. J Immunol (1970) 1.54
Increased immunoglobulin-secreting cells in the blood of patients with active systemic lupus erythematosus. Am J Med (1980) 1.53
Decreased autologous mixed lymphocyte reaction in Sjögren's syndrome. J Clin Invest (1980) 1.52
Approach to the study of the role of sex hormones in autoimmunity. Arthritis Rheum (1979) 1.51
Shared idiotypes and restricted immunoglobulin variable region heavy chain genes characterize murine autoantibodies of various specificities. J Clin Invest (1986) 1.48
Correlation between clinical activity of systemic lupus erythematosus and the amounts of DNA in DNA/anti-DNA antibody immune complexes. J Immunol (1982) 1.47
Presence of autoantibody for phospholipase inhibitory protein, lipomodulin, in patients with rheumatic diseases. Proc Natl Acad Sci U S A (1981) 1.47
Heterogeneity of immunoregulatory T-cell subsets in systemic lupus erythematosus. Correlation with clinical features. Am J Med (1982) 1.46
A defect of immunoregulatory T cell subsets in systemic lupus erythematosus patients demonstrated with anti-2H4 antibody. J Clin Invest (1987) 1.46
Studies of consomic mice bearing the Y chromosome of the BXSB mouse. J Immunol (1985) 1.44
Immunoglobulin synthesis by salivary gland lymphoid cells in Sjögren's syndrome. J Clin Invest (1970) 1.44
Sjögren's syndrome comes of age. Semin Arthritis Rheum (1999) 1.43
Delayed androgen treatment prolongs survival in murine lupus. J Clin Invest (1979) 1.43
Pathogenesis of autoimmunity in New Zealand mice. V. Loss of thymic suppressor function. Arthritis Rheum (1974) 1.42
Renal flares are common in patients with severe proliferative lupus nephritis treated with pulse immunosuppressive therapy: long-term followup of a cohort of 145 patients participating in randomized controlled studies. Arthritis Rheum (2002) 1.42
Treatment of NZB/NZW F1 hybrid mice with Mycobacterium bovis strain BCG or type II interferon preparations accelerates autoimmune disease. Arthritis Rheum (1981) 1.41