Published in Proc Natl Acad Sci U S A on August 01, 1974
Estimation of the lifespan of amiloride binding sites in the membranes of toad bladder epithelial cells. J Physiol (1976) 0.90
Comparison of toad bladder aldosterone-induced proteins and proteins synthesized in vitro using aldosterone-induced messenger RNA as template. J Membr Biol (1978) 0.85
Role of RNA in the action of aldosterone on Na+ transport. J Membr Biol (1978) 0.82
Mineralocorticoid-specificity of aldosterone-induced protein synthesis in giant-toad (Bufo marinus) urinary bladders. Biochem J (1983) 0.77
Static fusimotor component of the pinna reflex. J Physiol (1975) 0.76
Steroid-induced protein synthesis in giant-toad (Bufo marinus) urinary bladders. Correlation with natriferic activity. Biochem J (1984) 0.75
A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. Biochem J (1956) 124.75
Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose. Proc Natl Acad Sci U S A (1972) 83.88
RNA metabolism in the HeLa cell nucleus. J Mol Biol (1966) 17.11
The determination of nucleic acids. Methods Biochem Anal (1966) 4.79
ON THE MECHANISM OF ACTION OF ALDOSTERONE ON SODIUM TRANSPORT: THE ROLE OF PROTEIN SYNTHESIS. Proc Natl Acad Sci U S A (1963) 2.87
Studies on renal aldosterone-binding proteins. J Biol Chem (1968) 1.87
Characteristics of the renal nuclear receptors for aldosterone. Proc Natl Acad Sci U S A (1966) 1.61
OCCURRENCE AND FUNCTION OF POLYSOMES IN RABBIT RETICULOCYTES. J Mol Biol (1964) 1.41
ON THE MECHANISM OF ACTION OF ALDOSTERONE ON SODIUM TRANSPORT: THE ROLE OF RNA SYNTHESIS. Proc Natl Acad Sci U S A (1964) 1.32
On the mechanism of action of aldosterone on sodium transport: effects of inhibitors of RNA and of protein synthesis. Fed Proc (1966) 1.17
Renal aldosterone receptors: studies with (3H)aldosterone and the anti-mineralocorticoid (3H)spirolactone (SC-26304). Proc Natl Acad Sci U S A (1974) 1.11
Induction of RNA and protein synthesis in the action of aldosterone in the rat. Am J Physiol (1967) 1.09
Reversible stimulation of sodium transport in the toad bladder by stretch. J Clin Invest (1969) 1.05
Relationships between renal cytoplasmic and nuclear aldosterone-receptors. Kidney Int (1972) 1.00
Cordycepin and alpha-amanitin: inhibitors of transcription as probes of aldosterone action. J Membr Biol (1972) 0.94
The action of aldosterone on sodium transport: further studies with inhibitors of RNA and protein synthesis. Endocrinology (1973) 0.90
Effects of aldosterone on RNA polymerase in rat heart and kidney nuclei. Endocrinology (1972) 0.87
Kinetics of RNA synthesis in toad bladder epithelium: action of aldosterone during the latent period. J Clin Invest (1971) 0.81
Effects of aldosterone on RNA and protein synthesis in the toad bladder. Eur J Biochem (1972) 0.80
Effects of sodium transport stimulating substances on enzyme activities in the toad bladder. Pflugers Arch (1970) 0.80
The effect of temperature and substrate concentration on the kinetics of (6- 3 H)uridine incorporation into RNA of toad bladder epithelial cells: the role of aldosterone. Biochim Biophys Acta (1972) 0.79
The effects of aldosterone on toad bladder. Measurements of ( 3 H)uridine incorporation into RNA. Biochim Biophys Acta (1971) 0.79
Modification of rat renal cortical chromatin by aldosterone treatment. Can J Biochem (1971) 0.79
Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8). Proc Natl Acad Sci U S A (1996) 12.89
Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits. Nature (1994) 9.76
CFTR as a cAMP-dependent regulator of sodium channels. Science (1995) 6.50
Epithelial sodium channel related to proteins involved in neurodegeneration. Nature (1993) 6.04
Early death due to defective neonatal lung liquid clearance in alpha-ENaC-deficient mice. Nat Genet (1996) 4.15
An epithelial serine protease activates the amiloride-sensitive sodium channel. Nature (1997) 3.87
Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalaemic acidosis, pseudohypoaldosteronism type 1. Nat Genet (1996) 3.58
Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: a quantitative approach. Proc Natl Acad Sci U S A (1996) 3.37
Body Composition: Studies in the Human Being by the Dilution Principle. Science (1952) 3.27
Corticosteroid-dependent sodium transport in a novel immortalized mouse collecting duct principal cell line. J Am Soc Nephrol (1999) 2.88
A mutation in the epithelial sodium channel causing Liddle disease increases channel activity in the Xenopus laevis oocyte expression system. Proc Natl Acad Sci U S A (1995) 2.69
Membrane topology of the epithelial sodium channel in intact cells. Am J Physiol (1994) 2.69
Identification of a PY motif in the epithelial Na channel subunits as a target sequence for mutations causing channel activation found in Liddle syndrome. EMBO J (1996) 2.39
The heterotetrameric architecture of the epithelial sodium channel (ENaC). EMBO J (1998) 2.34
Distribution of transcellular calcium and sodium transport pathways along mouse distal nephron. Am J Physiol Renal Physiol (2001) 2.28
Cell-specific expression of epithelial sodium channel alpha, beta, and gamma subunits in aldosterone-responsive epithelia from the rat: localization by in situ hybridization and immunocytochemistry. J Cell Biol (1994) 2.18
Aldosterone induces rapid apical translocation of ENaC in early portion of renal collecting system: possible role of SGK. Am J Physiol Renal Physiol (2001) 2.13
A de novo missense mutation of the beta subunit of the epithelial sodium channel causes hypertension and Liddle syndrome, identifying a proline-rich segment critical for regulation of channel activity. Proc Natl Acad Sci U S A (1995) 2.10
An SH3 binding region in the epithelial Na+ channel (alpha rENaC) mediates its localization at the apical membrane. EMBO J (1994) 2.10
The mechanism of the calorigenic action of thyroid hormone. Stimulation of Na plus + K plus-activated adenosinetriphosphatase activity. J Gen Physiol (1971) 2.07
A role for the beta-subunit in the expression of functional Na+-K+-ATPase in Xenopus oocytes. Am J Physiol (1989) 1.92
Studies on renal aldosterone-binding proteins. J Biol Chem (1968) 1.87
Cloning and gene mapping of the chromosome 13q14 region deleted in chronic lymphocytic leukemia. Genomics (1997) 1.68
The highly selective low-conductance epithelial Na channel of Xenopus laevis A6 kidney cells. Am J Physiol (1995) 1.65
Subcellular mechanisms in the action of adrenal steroids. Am J Med (1972) 1.65
Transcriptome of a mouse kidney cortical collecting duct cell line: effects of aldosterone and vasopressin. Proc Natl Acad Sci U S A (2001) 1.64
Mechanism of thyroid calorigenesis: role of active sodium transport. Proc Natl Acad Sci U S A (1970) 1.61
Characteristics of the renal nuclear receptors for aldosterone. Proc Natl Acad Sci U S A (1966) 1.61
Cystic fibrosis transmembrane conductance regulator inverts protein kinase A-mediated regulation of epithelial sodium channel single channel kinetics. J Biol Chem (1997) 1.61
Aldosterone-induced increase in the abundance of Na+ channel subunits. Am J Physiol (1996) 1.59
Activation of the amiloride-sensitive epithelial sodium channel by the serine protease mCAP1 expressed in a mouse cortical collecting duct cell line. J Am Soc Nephrol (2000) 1.58
Egr transcription factors in the nervous system. Neurochem Int (1997) 1.56
Glutamate-mediated transmission, alcohol, and alcoholism. Neurochem Int (2000) 1.54
Calcium dependence of glucocorticoid-induced lymphocytolysis. Proc Natl Acad Sci U S A (1977) 1.53
Differential subcellular localization of ENaC subunits in mouse kidney in response to high- and low-Na diets. Am J Physiol Renal Physiol (2000) 1.47
Mutational analysis of cysteine-rich domains of the epithelium sodium channel (ENaC). Identification of cysteines essential for channel expression at the cell surface. J Biol Chem (1999) 1.46
A mutation causing pseudohypoaldosteronism type 1 identifies a conserved glycine that is involved in the gating of the epithelial sodium channel. EMBO J (1997) 1.46
Mutations causing Liddle syndrome reduce sodium-dependent downregulation of the epithelial sodium channel in the Xenopus oocyte expression system. J Clin Invest (1998) 1.45
Early effect of aldosterone on the rate of synthesis of the epithelial sodium channel alpha subunit in A6 renal cells. J Am Soc Nephrol (1997) 1.39
Primary sequence and functional expression of a novel ouabain-resistant Na,K-ATPase. The beta subunit modulates potassium activation of the Na,K-pump. J Biol Chem (1992) 1.38
A mouse model for the renal salt-wasting syndrome pseudohypoaldosteronism. Proc Natl Acad Sci U S A (1997) 1.37
Epithelial Na+ channel subunits in rat taste cells: localization and regulation by aldosterone. J Comp Neurol (1999) 1.37
Salt restriction induces pseudohypoaldosteronism type 1 in mice expressing low levels of the beta-subunit of the amiloride-sensitive epithelial sodium channel. Proc Natl Acad Sci U S A (1999) 1.33
On the biochemical mechanism of action of aldosterone. Recent Prog Horm Res (1968) 1.32
Thyroid thermogenesis. Relationships between Na+-dependent respiration and Na+ + K+-adenosine triphosphatase activity in rat skeletal muscle. J Clin Invest (1976) 1.31
Liddle disease caused by a missense mutation of beta subunit of the epithelial sodium channel gene. J Clin Invest (1996) 1.30
A mouse model for Liddle's syndrome. J Am Soc Nephrol (1999) 1.30
Effect of triiodothyronine on the synthesis and degradation of renal cortical (Na+ + k+)-adenosine triphosphatase. J Biol Chem (1976) 1.28
Modulation of the Na,K-pump function by beta subunit isoforms. J Gen Physiol (1994) 1.28
Thyroid thermogenesis. N Engl J Med (1974) 1.23
Stereospecific binding of aldosterone to renal chromatin. J Biol Chem (1970) 1.22
Aldosterone control of the density of sodium channels in the toad urinary bladder. J Membr Biol (1982) 1.22
Lung epithelial Na channel subunits are differentially regulated during development and by steroids. Am J Physiol (1995) 1.21
Amiloride-sensitive trypsinization of apical sodium channels. Analysis of hormonal regulation of sodium transport in toad bladder. J Gen Physiol (1983) 1.21
Relative expression of the human epithelial Na+ channel subunits in normal and cystic fibrosis airways. Am J Physiol (1995) 1.19
Phosphorylation of the Na,K-ATPase alpha-subunit by protein kinase A and C in vitro and in intact cells. Identification of a novel motif for PKC-mediated phosphorylation. J Biol Chem (1994) 1.19
Hormonal regulation of (Na+,K+)-ATPase biosynthesis in the toad bladder. Effect of aldosterone and 3,5,3'-triiodo-L-thyronine. J Biol Chem (1982) 1.18
On the mechanism of action of aldosterone on sodium transport: effects of inhibitors of RNA and of protein synthesis. Fed Proc (1966) 1.17
Mutation of a cysteine in the first transmembrane segment of Na,K-ATPase alpha subunit confers ouabain resistance. EMBO J (1992) 1.17
Dependence of renal (Na+ + k+)-adenosine triphosphatase activity on thyroid status. J Biol Chem (1976) 1.17
Aldosterone regulation of gene transcription leading to control of ion transport. Hypertension (1992) 1.17
Processing, intracellular transport, and functional expression of endogenous and exogenous alpha-beta 3 Na,K-ATPase complexes in Xenopus oocytes. J Biol Chem (1992) 1.15
Effects of thyroid status on electrolyte distribution in rat tissues. Am J Physiol (1973) 1.14
Effects of Ca++ and prostaglandin E1 on vasopressin activation of renal adenyl cyclase. J Clin Invest (1971) 1.14
The role of sodium-channel density in the natriferic response of the toad urinary bladder to an antidiuretic hormone. J Membr Biol (1982) 1.14
Current-voltage analysis of apical sodium transport in toad urinary bladder: effects of inhibitors of transport and metabolism. J Membr Biol (1980) 1.13
Renal aldosterone receptors: studies with (3H)aldosterone and the anti-mineralocorticoid (3H)spirolactone (SC-26304). Proc Natl Acad Sci U S A (1974) 1.11
Glucocorticoid receptors in rat kidney: the binding of tritiated-dexamethasone. Endocrinology (1973) 1.10
Induction of RNA and protein synthesis in the action of aldosterone in the rat. Am J Physiol (1967) 1.09
Primary sequence of Xenopus laevis Na+-K+-ATPase and its localization in A6 kidney cells. Am J Physiol (1989) 1.09
Molecular modifications of anti-aldosterone compounds: effects on affinity of spirolactones for renal aldosterone receptors. Biochem Pharmacol (1974) 1.07
Membrane insertion of alpha- and beta-subunits of Na+,K+-ATPase. J Biol Chem (1985) 1.07
IGF-1 vs insulin: respective roles in modulating sodium transport via the PI-3 kinase/Sgk1 pathway in a cortical collecting duct cell line. Kidney Int (2006) 1.06
Regulation by aldosterone of Na+,K+-ATPase mRNAs, protein synthesis, and sodium transport in cultured kidney cells. J Cell Biol (1987) 1.06
Expression of the epithelial Na+ channel in the developing rat lung. Am J Physiol (1993) 1.06
Structure-function relationship of Na,K-ATPase. Annu Rev Physiol (1991) 1.04
Coexpression of alpha 1 with putative beta 3 subunits results in functional Na+/K+ pumps in Xenopus oocytes. Proc Natl Acad Sci U S A (1991) 1.04
Role of the transmembrane and extracytoplasmic domain of beta subunits in subunit assembly, intracellular transport, and functional expression of Na,K-pumps. J Cell Biol (1993) 1.03
Thyroid hormone control of Na+-K+-ATPase and K+-dependent phosphatase in rat heart. Am J Physiol (1977) 1.03
Thyroid thermogenesis and active sodium transport. Recent Prog Horm Res (1974) 1.03
Identification of a highly conserved sequence at the N-terminus of the epithelial Na+ channel alpha subunit involved in gating. Pflugers Arch (1999) 1.02
Epithelial sodium channel regulatory proteins identified by functional expression cloning. Kidney Int Suppl (1998) 1.00
Relationships between renal cytoplasmic and nuclear aldosterone-receptors. Kidney Int (1972) 1.00
Comparative gene expression in brain regions of human alcoholics. Genes Brain Behav (2006) 1.00
Primary structure of an apical protein from Xenopus laevis that participates in amiloride-sensitive sodium channel activity. J Cell Biol (1992) 0.99
Assembly of the (Na+ + K+)-adenosine triphosphatase. Post-translational membrane integration of the alpha subunit. J Biol Chem (1984) 0.99
The roles of plasma binding and receptor specificity in the mineralocorticoid action of aldosterone. Endocrinology (1973) 0.99
Immunochemical evidence for a transmembrane orientation of both the (Na+, K+)-ATPase subunits. Biochemistry (1981) 0.99
Functional expression of a pseudohypoaldosteronism type I mutated epithelial Na+ channel lacking the pore-forming region of its alpha subunit. J Clin Invest (1999) 0.99
Hydrogen-ion dependence of the antidiuretic action of vasopressin, oxytocin and deaminooxytocin. Biochim Biophys Acta (1965) 0.98
Iodination (125I) of the apical plasma membrane of toad bladder epithelium: electron-microscopic autoradiography and physiological effects. J Membr Biol (1973) 0.98
Developmental expression of sodium entry pathways in rat nephron. Am J Physiol (1999) 0.98
Smoking and alcoholism target genes associated with plasticity and glutamate transmission in the human ventral tegmental area. Hum Mol Genet (2007) 0.98
Time-course of the effects of thyroid hormone on respiration and Na+ + K+-ATPase activity in rat liver. Proc Soc Exp Biol Med (1974) 0.97
The role of sodium transport in thyroid thermogenesis. Fed Proc (1979) 0.96
Auto-anti-idiotype: a basis for autoimmunity and a strategy for anti-receptor antibodies. Immunol Rev (1986) 0.96
The H,K-ATPase beta-subunit can act as a surrogate for the beta-subunit of Na,K-pumps. J Biol Chem (1991) 0.96
Novel isoforms of the beta and gamma subunits of the Xenopus epithelial Na channel provide information about the amiloride binding site and extracellular sodium sensing. Proc Natl Acad Sci U S A (1997) 0.96
A putative H(+)-K(+)-ATPase is selectively expressed in surface epithelial cells of rat distal colon. Am J Physiol (1993) 0.96
Mechanism of action of steroid hormones. J Steroid Biochem (1976) 0.96