Published in Am Rev Respir Dis on February 01, 1979
Sonic hedgehog mediates the polarizing activity of the ZPA. Cell (1993) 8.67
Beneficial effects of combined colestipol-niacin therapy on coronary atherosclerosis and coronary venous bypass grafts. JAMA (1987) 5.82
The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog. Nature (1996) 5.69
Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog. Genes Dev (1996) 4.94
Diffusion of the Interspecies Electron Carriers H(2) and Formate in Methanogenic Ecosystems and Its Implications in the Measurement of K(m) for H(2) or Formate Uptake. Appl Environ Microbiol (1989) 4.53
Randomised, controlled trial of efficacy of midwife-managed care. Lancet (1996) 4.21
End-of-life decisions in neonatal intensive care: physicians' self-reported practices in seven European countries. EURONIC Study Group. Lancet (2000) 4.01
Requirement for math5 in the development of retinal ganglion cells. Genes Dev (2001) 3.26
Mutations in LMX1B cause abnormal skeletal patterning and renal dysplasia in nail patella syndrome. Nat Genet (1998) 3.18
Parental visiting, communication, and participation in ethical decisions: a comparison of neonatal unit policies in Europe. Arch Dis Child Fetal Neonatal Ed (1999) 3.14
Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud. Cell (1994) 2.98
Lymphokine stimulation of collagen accumulation. J Clin Invest (1976) 2.94
Function of Rieger syndrome gene in left-right asymmetry and craniofacial development. Nature (1999) 2.78
Randomised controlled trial of routine cervical examinations in pregnancy. European Community Collaborative Study Group on Prenatal Screening. Lancet (1994) 2.74
Gas exchange efficiency in congestive heart failure II. Circulation (2001) 2.71
A molecular pathway determining left-right asymmetry in chick embryogenesis. Cell (1995) 2.65
Presacral tumors and cysts in adults. Dis Colon Rectum (1975) 2.63
Recruitment of a hedgehog regulatory circuit in butterfly eyespot evolution. Science (1999) 2.55
A chemoattractant receptor controls development in Dictyostelium discoideum. Science (1988) 2.54
Medical genetic services in 31 countries: an overview. Eur J Hum Genet (1997) 2.33
Distinct WNT pathways regulating AER formation and dorsoventral polarity in the chick limb bud. Science (1998) 2.28
Sonic hedgehog is an endodermal signal inducing Bmp-4 and Hox genes during induction and regionalization of the chick hindgut. Development (1995) 2.25
Should euthanasia be legal? An international survey of neonatal intensive care units staff. Arch Dis Child Fetal Neonatal Ed (2004) 2.21
A second independent pathway for development of mesencephalic dopaminergic neurons requires Lmx1b. Nat Neurosci (2000) 2.20
Coordinate roles for LIM homeobox genes in directing the dorsoventral trajectory of motor axons in the vertebrate limb. Cell (2000) 2.19
Treatment choices for extremely preterm infants: an international perspective. J Pediatr (2000) 2.19
Spatial regulation of a zebrafish patched homologue reflects the roles of sonic hedgehog and protein kinase A in neural tube and somite patterning. Development (1996) 2.18
Limb and kidney defects in Lmx1b mutant mice suggest an involvement of LMX1B in human nail patella syndrome. Nat Genet (1998) 2.09
lunatic fringe is an essential mediator of somite segmentation and patterning. Nature (1998) 2.09
Drug misusers in Lothian: changes in injecting habits 1988-90. BMJ (1993) 2.09
The winged-helix transcription factor FoxD3 is important for establishing the neural crest lineage and repressing melanogenesis in avian embryos. Development (2001) 2.02
Identification of mutations in the human PATCHED gene in sporadic basal cell carcinomas and in patients with the basal cell nevus syndrome. J Invest Dermatol (1998) 2.00
Noninvasive determination of cardiac output by a modified acetylene rebreathing procedure utilizing mass spectrometer measurements. Aviat Space Environ Med (1977) 1.97
Iatrogenic rickets in low-birth-weight infants. J Pediatr (1971) 1.90
Sonic hedgehog differentially regulates expression of GLI and GLI3 during limb development. Dev Biol (1996) 1.85
Mutations of the PATCHED gene in several types of sporadic extracutaneous tumors. Cancer Res (1997) 1.83
Microscopic counting and adenosine 5'-triphosphate measurement in determining microbial growth in soils. Appl Environ Microbiol (1977) 1.80
Conservation in hedgehog signaling: induction of a chicken patched homolog by Sonic hedgehog in the developing limb. Development (1996) 1.80
Simulation-based training in anaesthesiology: a systematic review and meta-analysis. Br J Anaesth (2013) 1.79
Targeted Disruption of the Myocilin Gene (Myoc) Suggests that Human Glaucoma-Causing Mutations Are Gain of Function. Mol Cell Biol (2001) 1.75
Randomized European multicenter trial of surfactant replacement therapy for severe neonatal respiratory distress syndrome: single versus multiple doses of Curosurf. Pediatrics (1992) 1.71
What is the excess risk of infertility in women after genital chlamydia infection? A systematic review of the evidence. Sex Transm Infect (2007) 1.68
The influence of diet on the appearance of new lesions in human coronary arteries. JAMA (1990) 1.63
Response to exercise after bed rest and after training. Circulation (1968) 1.61
Extraction of immune and inflammatory cells from human lung parenchyma: evaluation of an enzymatic digestion procedure. Clin Exp Immunol (1986) 1.57
HIV-relevant sexual behavior among a healthy inner-city heterosexual adolescent population in an endemic area of HIV. J Adolesc Health (1991) 1.55
Neonatal end-of-life decision making: Physicians' attitudes and relationship with self-reported practices in 10 European countries. JAMA (2000) 1.49
An outbreak of illness among aerospace workers. West J Med (1990) 1.49
The distribution of rods and cones in the retina of the cat (Felis domesticus). J Comp Neurol (1973) 1.47
Measurement of human converting enzyme level by direct radioimmunoassay. J Lab Clin Med (1983) 1.45
Red cell distribution and the recruitment of pulmonary diffusing capacity. J Appl Physiol (1985) (1999) 1.45
Use of GUM services and information and views held by first time service users in a large UK city: implications for information provision. Int J STD AIDS (1997) 1.44
Pediatric residency education. Pediatrics (2000) 1.43
Effects of nerve growth factor on nerve regeneration through a vein graft across a gap. Plast Reconstr Surg (1999) 1.43
Abnormal superior popliteomeniscal fascicle and posterior pericapsular edema: indirect MR imaging signs of a lateral meniscal tear. AJR Am J Roentgenol (2001) 1.42
Stability of positive tuberculin tests: are boosted reactions valid? Am Rev Respir Dis (1991) 1.42
Newborn sickle cell disease screening: the Jamaican experience (1995-2006). J Med Screen (2007) 1.41
A finite-element model of oxygen diffusion in the pulmonary capillaries. J Appl Physiol (1985) (1997) 1.41
Pain after vasectomy. Anaesthesia (1998) 1.39
Dynamic expression of lunatic fringe suggests a link between notch signaling and an autonomous cellular oscillator driving somite segmentation. Dev Biol (1999) 1.39
Identification and expression of a novel family of bHLH cDNAs related to Drosophila hairy and enhancer of split. Biochem Biophys Res Commun (1999) 1.38
Intraoperative cholangiography: use of portable fluoroscopy and transmitted images. Radiology (1991) 1.38
A comparative study of the quality and availability of health information used to facilitate cost burden analysis of diabetes and hypertension in the Caribbean. West Indian Med J (2008) 1.38
"Healthy alliances?"--other sexual health services and their views of genitourinary medicine. Genitourin Med (1995) 1.38
Interaction of Ihh and BMP/Noggin signaling during cartilage differentiation. Dev Biol (1999) 1.37
Personal Paper: Orthopaedic scooter. Br Med J (Clin Res Ed) (1986) 1.37
The role of cholesterol and glycosylphosphatidylinositol-anchored proteins of erythrocyte rafts in regulating raft protein content and malarial infection. J Biol Chem (2001) 1.37
Incidence and survival for cancer in children and young adults in the North of England, 1968-1995: a report from the Northern Region Young Persons' Malignant Disease Registry. Br J Cancer (2000) 1.29
Pulmonary membrane diffusing capacity and capillary blood volume measured during exercise from nitric oxide uptake. Chest (2001) 1.28
Lymphotoxin formation by lymphocytes and muscle in polymyositis. J Clin Invest (1972) 1.26
Expression of a cAMP receptor gene of Dictyostelium and evidence for a multigene family. Genes Dev (1991) 1.23
LMX1B, a LIM homeodomain class transcription factor, is necessary for normal development of multiple tissues in the anterior segment of the murine eye. Genesis (2000) 1.22
Control of dorsoventral somite patterning by Wnt-1 and beta-catenin. Dev Biol (1998) 1.20
Circadian and interpersonal variability of IgA in nasal secretions. Ann Otol Rhinol Laryngol (1973) 1.20
Myristic acid auxotrophy caused by mutation of S. cerevisiae myristoyl-CoA:protein N-myristoyltransferase. J Cell Biol (1991) 1.18
Endogenous and ectopic expression of noggin suggests a conserved mechanism for regulation of BMP function during limb and somite patterning. Dev Biol (1998) 1.16
The effects of acid-base disturbances on cardiovascular and pulmonary function. Kidney Int (1972) 1.15
Gas exchange efficiency in congestive heart failure. Circulation (2000) 1.15
Treatment of trichiasis with a lid cryoprobe. Br J Ophthalmol (1985) 1.14
Controlled oxygen administration in acute respiratory failure in chronic obstructive pulmonary disease: a reappraisal. Am J Med (1978) 1.13
Comparison of myristoyl-CoA:protein N-myristoyltransferases from three pathogenic fungi: Cryptococcus neoformans, Histoplasma capsulatum, and Candida albicans. J Biol Chem (1994) 1.11
Topoisomerase IIalpha expression in breast cancer: correlation with outcome variables. Mod Pathol (2000) 1.11
The Cholesterol Lowering Atherosclerosis Study (CLAS): design, methods, and baseline results. Control Clin Trials (1987) 1.09
Controlled trial of new formulae for feeding low birth weight infants. Early Hum Dev (1986) 1.09
The relationship of respiratory failure to the oxygen consumption of, lactate production by, and distribution of blood flow among respiratory muscles during increasing inspiratory resistance. J Clin Invest (1977) 1.08
Auditory processing parallels reading abilities in adults. Proc Natl Acad Sci U S A (2000) 1.08
Balancing inflammatory, lipid, and xenobiotic signaling pathways by VSL#3, a biotherapeutic agent, in the treatment of inflammatory bowel disease. Inflamm Bowel Dis (2009) 1.08
Sexual victimization of boys. Experience at an adolescent medicine clinic. J Adolesc Health Care (1985) 1.07
Bacillus thuringiensis-toxin resistance management: stable isotope assessment of alternate host use by Helicoverpazea. Proc Natl Acad Sci U S A (2002) 1.07
Novel regulatory interactions revealed by studies of murine limb pattern in Wnt-7a and En-1 mutants. Development (1997) 1.07
Isolation and characterization of an ether glucuronide of zidovudine, a major metabolite in monkeys and humans. Drug Metab Dispos (1990) 1.07
Functional capacities of lungs and thorax in beagles after prolonged residence at 3,100 m. J Appl Physiol (1985) (1985) 1.07
Glycosaminoglycan synthesis by the early embryonic chick heart. Dev Biol (1973) 1.07
Electronic structure of Pd nanoparticles on carbon nanotubes. Micron (2008) 1.06
Amino acid absorption by mouse ascites-tumour cells depleted of both endogenous amino acids and adenosine triphosphate. Biochem J (1973) 1.06
Effect of lung inflation on pulmonary diffusing capacity at rest and exercise. J Clin Invest (1966) 1.05
Effects of moderate physical exercise during four weeks of bed rest on circulatory functions in man. Aerosp Med (1965) 1.04
The risk of mortality among older adults over an eight-year period. Gerontologist (1995) 1.04
Interaction of L-prolyl-L-leucyl glycinamide with dopamine D2 receptor: evidence for modulation of agonist affinity states in bovine striatal membranes. J Neurochem (1988) 1.02
1 alpha-hydroxyvitamin D in nutritional rickets. Lancet (1977) 1.02