Published in J Exp Med on September 01, 1973
On the role of the H-2 histocompatibility complex in determining the specificity of cytotoxic effector cells sensitized against syngeneic trinitrophenyl-modified targets. J Exp Med (1975) 2.48
Role of H-2 lymphocyte-defined and serologically-defined components in the generation of cytotoxic lymphocytes. J Exp Med (1974) 2.01
Joint recognition by cytotoxic T cells of inactivated Sendai virus and products of the major histocompatibility complex. J Exp Med (1977) 1.83
A clone-specific monoclonal antibody that inhibits cytolysis of a cytolytic T cell clone. J Exp Med (1983) 1.48
Absence of H-2 antigens capable of reacting with cytotoxic T cells on a teratoma line expressing a T/t locus antigen. Proc Natl Acad Sci U S A (1975) 1.43
Cytotoxic T lymphocyte hybridomas that mediate specific tumor-cell lysis in vitro. Proc Natl Acad Sci U S A (1981) 1.36
Glycosylation of the T-cell antigen-specific receptor and its potential role in lectin-mediated cytotoxicity. Proc Natl Acad Sci U S A (1986) 1.04
Helper T cells are required for the polyclonal stimulation of cytotoxic T cells by concanavalin A. J Exp Med (1977) 0.98
Wheat-germ agglutinin initiates monocytoid cell killing of non-antibody-coated erythrocytes. Immunology (1983) 0.78
T lymphocyte-mediated cytolysis. III. Delineation of mechanisms whereby mitogenic and non-mitogenic lectins mediate lymphocyte-target interaction. Immunology (1983) 0.76
Cytotoxic T-cell activation by polyribonucleotides: DNA synthesis is not required. J Exp Med (1977) 0.75
Immunization of dissociated spleen cell cultures from normal mice. J Exp Med (1967) 30.93
A receptor for antibody on B lymphocytes. I. Method of detection and functional significance. J Exp Med (1972) 7.47
Immunization of normal mouse spleen cell suspensions in vitro. Science (1966) 6.47
Interaction of the carbohydrate-binding protein concanavalin A with normal and transformed cells. Proc Natl Acad Sci U S A (1969) 5.39
Mechanism of immunologically specific killing of tumour cells by macrophages. Nature (1972) 4.63
Evidence for a receptor recognizing antigen complexed immunoglobulin on the surface of activated mouse thymus lymphocytes. Scand J Immunol (1972) 4.50
Quantitative studies on the mixed lymphocyte interaction in rats. II. Relationship of the proliferative response to the immunologic status of the donors. J Exp Med (1967) 3.82
In vitro approaches to the mechanism of cell-mediated immune reactions. Adv Immunol (1971) 3.49
Quantitative in vitro assay of cytotoxic cellular immunity. J Natl Cancer Inst (1970) 3.12
Origin of immunoreactive lymphocytes in rats. Cell Immunol (1970) 2.30
Cell-mediated immune response in vitro. II. The role of thymus and thymus-derived lymphocytes. Cell Immunol (1972) 2.15
Cells mediating specific in vitro cytotoxicity. I. Detection of receptor-bearing lymphocytes. J Exp Med (1971) 2.09
Specificiy of lymphocyte-mediated cytotoxicity induced by in vitro antibody-coated target cells. Cell Immunol (1972) 1.93
When allogeneic mouse spleen cells are mixed in vitro the T-cells secrete a product which guides the maturation of B-cells. Scand J Immunol (1972) 1.73
Cellular immunoabsorbents in transplantation immunity. Specific in vitro deletion and recovery of mouse lymphoid cells sensitized against allogeneic tumors. J Exp Med (1972) 1.27
Tumor-graft rejection in syngeneic guinea pigs: evidence for a two-step mechanism. J Natl Cancer Inst (1970) 1.27
Mitogen-induced lymphocyte-mediated cytotoxicity in vitro: effect of mitogens selectively activating T or B cells. Eur J Immunol (1972) 1.26
T-cell mediated immunity in vitro: an analysis of antigen recognition and target cell lysis. Transplant Rev (1972) 1.19
Fractionation of specific antigen-reactive cells in an in vitro system of cell-mediated immunity. Nat New Biol (1972) 1.17
The lysis of fibroblasts by lymphocytes sensitized in vitro: specific antigen activates a nonspecific effect. Cell Immunol (1970) 1.10
On the specificity of cell-mediated cytotoxicity in vitro. Cell Immunol (1970) 1.05
Heterogeneity of the effector cells in the cytotoxic reaction against allogeneic lymphoma cells. J Exp Med (1973) 0.98
Specificity of homograft rejection in vivo, assessed by inoculation of artificially mixed compatible and incompatible tumor cells. Cell Immunol (1972) 0.81
Regulatory effect of antibody on the immune response. Adv Immunol (1968) 6.03
Mitogens as probes for immunocyte activation and cellular cooperation. Transplant Rev (1972) 5.66
Selective induction of DNA synthesis in T and B lymphocytes. Cell Immunol (1972) 4.94
Induction of immunoglobulin and antibody synthesis in vitro by lipopolysaccharides. Eur J Immunol (1972) 4.64
Differential effects of human granulocytes and lymphocytes on human fibroblasts in vitro. Clin Exp Immunol (1968) 3.38
Helper activity is required for the in vivo generation of cytotoxic T lymphocytes. J Exp Med (1982) 3.34
Thymus-independent B-cell induction and paralysis. Adv Immunol (1975) 3.27
Vaccination with a recombinant vesicular stomatitis virus expressing an influenza virus hemagglutinin provides complete protection from influenza virus challenge. J Virol (1998) 3.07
Attenuated vesicular stomatitis viruses as vaccine vectors. J Virol (1999) 3.04
Editorial: Immune activation of B cells: evidence for 'one nonspecific triggering signal' not delivered by the Ig receptors. Scand J Immunol (1974) 2.93
Lipopolysaccharide can substitute for helper cells in the antibody response in vitro. Eur J Immunol (1972) 2.58
On the role of the H-2 histocompatibility complex in determining the specificity of cytotoxic effector cells sensitized against syngeneic trinitrophenyl-modified targets. J Exp Med (1975) 2.48
Subcutaneous immunoglobulin replacement in patients with primary antibody deficiencies: safety and costs. Lancet (1995) 2.43
Activation of B lymphocytes by locally concentrated concanavalin A. Eur J Immunol (1972) 2.41
Frequency of antigen-sensitive cells to thymus-independent antigens. Cell Immunol (1971) 2.39
Ham-2 corrects the class I antigen-processing defect in RMA-S cells. Nature (1992) 2.27
Regulation of antibody synthesis against Escherichia coli endotoxin. I. Suppressive effect of endogenously produced and passively transferred antibodies. J Immunol (1968) 2.18
19S antibody production against soluble lipopolysaccharide antigens by individual lymphoid cells in vitro. Nature (1965) 2.12
Mechanism of thymus-independent immunocyte triggering. Mitogenic activation of B cells results in specific immune responses. J Exp Med (1974) 2.04
Induction of DNA synthesis in normal human lymphocyte cultures by antigen-antibody complexes. Clin Exp Immunol (1969) 2.03
Specificiy of lymphocyte-mediated cytotoxicity induced by in vitro antibody-coated target cells. Cell Immunol (1972) 1.93
Studies at the cellular level of the 19S immune response. Acta Pathol Microbiol Scand (1966) 1.93
Identification of a Tap-dependent leader peptide recognized by alloreactive T cells specific for a class Ib antigen. Cell (1994) 1.92
Molecular basis of B-cell activation. I. Mitogenicity of native and substituted dextrans. Scand J Immunol (1974) 1.87
Persistence of immunogenicity of two complex antigens retained in vivo. Immunology (1968) 1.87
Expression and function of transplantation antigens with altered or deleted cytoplasmic domains. Cell (1983) 1.86
End-of-life decision making: when patients and surrogates disagree. J Clin Ethics (1999) 1.83
Polyclonal antibody secretion in human lymphocytes induced by killed staphylococcal bacteria and by lipopolysaccharide. Scand J Immunol (1977) 1.82
B lymphocytes can be stimulated by concanavalin A in the presence of humoral factors released by T cells. Eur J Immunol (1972) 1.81
B cell mitogenic properties of thymus-independent antigens. Nat New Biol (1973) 1.80
Multicentre study of a new enzymatic method of cholesterol determination. J Clin Chem Clin Biochem (1984) 1.77
Definitive identification of a gene that confers resistance against Toxoplasma cyst burden and encephalitis. Immunology (1995) 1.76
Cytotoxicity of human lymphocytes: antagonism between inducing processes. Nature (1968) 1.76
Reconstitution of the antibody response in vitro of T cell-deprived spleen cells by supernatants from spleen cell cultures. J Immunol (1972) 1.73
Effect of antigenic competition on antigen-sensitive cells and on adoptively transferred immunocompetent cells. Cell Immunol (1970) 1.71
T cell growth factor abrogates concanavalin A-induced suppressor cell function. J Exp Med (1981) 1.68
The role of the champion in infection prevention: results from a multisite qualitative study. Qual Saf Health Care (2009) 1.62
In vitro activation of mouse lymphocytes in serum-free medium: effect of T and B cell mitogens on proliferation and antibody synthesis. Eur J Immunol (1973) 1.62
Cyclosporin A blocks receptors for HLA-DR antigens on T cells. Nature (1981) 1.61
Differentiation of B cells: sequential appearance of responsiveness to polyclonal activators. Scand J Immunol (1974) 1.57
Technical principles for protoporphyrin-IX-fluorescence guided microsurgical resection of malignant glioma tissue. Acta Neurochir (Wien) (1998) 1.56
The effector cell in antibody-induced cell mediated immunity. Transplant Rev (1973) 1.56
Plaque-formation by non-immune and x-irradiated lymphoid cells on monolayers of mouse embryo cells. Nature (1965) 1.55
Non-specific induction of cytotoxicity in normal human lymphocytes in vitro: studies of mechanism and specificity of the reaction. Clin Exp Immunol (1969) 1.53
Requirement for adherent cells in the primary and secondary immune response in vitro. Eur J Immunol (1972) 1.51
Immunological unresponsiveness to thymus-independent antigens: two fundamentally different genetic mechanisms of B-cell unresponsiveness to dextran. J Exp Med (1977) 1.50
Lipopolysaccharides can convert heterologous red cells into thymus-independent antigens. Cell Immunol (1972) 1.48
Spleen cells from animals tolerant to a thymus-dependent antigen can be activated by lipopolysaccharide to synthesize antibodies against the tolerogen. J Exp Med (1976) 1.48
Effect of B-cell mitogens on lymphocyte subpopulations possesing C'3 and Fc receptors. J Exp Med (1974) 1.46
Suppressive effect of graft versus host reactions on the immune response to heterologous red cells. Immunology (1971) 1.45
Induction of DNA synthesis in human lymphocytes: interaction between non-specific mitogens and antigens. Immunology (1970) 1.45
Prolonged survival of H-2 incompatible skin allografts on F1 animals treated with parental lymphoid cells. Immunology (1969) 1.44
Simultaneous production of interleukin 2, interleukin 4 and interferon-gamma by activated human blood lymphocytes. Eur J Immunol (1990) 1.44
Absence of H-2 antigens capable of reacting with cytotoxic T cells on a teratoma line expressing a T/t locus antigen. Proc Natl Acad Sci U S A (1975) 1.43
Regulation of cellular antibody synthesis. Cellular 7S production and longevity of 7S antigen-sensitive cells in the absence of antibody feedback. J Exp Med (1968) 1.42
Lymphocytic responses to streptococcal antigens in glomerulonephritic patients. Science (1970) 1.39
H-2L-restricted recognition of viral antigens In the H-2d haplotype, anti-vesicular stomatitis virus cytotoxic T cells are restricted solely by H-2L. J Exp Med (1982) 1.39
Response to Listeria monocytogenes in mice lacking MHC class Ia molecules. J Immunol (1999) 1.38
The role of 17 beta-hydroxysteroid dehydrogenases. Mol Cell Endocrinol (2004) 1.37
One non-specific signal triggers b lymphocytes. Transplant Rev (1975) 1.36
Six-year follow-up of glutaraldehyde-preserved heterografts. With particular reference to the treatment of congenital valve malformations. J Thorac Cardiovasc Surg (1974) 1.35
Characterization of self-reactive B cells by polyclonal B-cell activators. J Exp Med (1977) 1.34
Cell surface immunoglobulin. XVIII. Functional differences of B lymphocytes bearing different surface immunoglobulin isotypes. J Exp Med (1976) 1.33
T cell vaccination induces T cell receptor Vbeta-specific Qa-1-restricted regulatory CD8(+) T cells. Proc Natl Acad Sci U S A (1998) 1.32
In vitro assay of cell-mediated immunity: the inhibition of migration of sensitized human lymphocytes by HL-A antigens. Clin Exp Immunol (1970) 1.32
In vitro induction of specific immune responses in the absence of serum: requirement for nonspecific T or B cell mitogens. Eur J Immunol (1973) 1.32
Studies on antigen-binding cells. II. Relationship to antigen-sensitive cells. Cell Immunol (1970) 1.31
Role of C'3 and Fc receptors in B-lymphocyte activation. J Exp Med (1975) 1.30
Left ventricular outflow obstruction after mitral valve repair (Carpentier's technique). Proposed mechanisms of disease. Circulation (1988) 1.27
MHC class Ib-restricted cells contribute to antilisterial immunity: evidence for Qa-1b as a key restricting element for Listeria-specific CTLs. J Immunol (1997) 1.26
Induction of autoantibodies to red blood cells by polyclonal B-cell activators. Nature (1976) 1.26
Mitogen-induced lymphocyte-mediated cytotoxicity in vitro: effect of mitogens selectively activating T or B cells. Eur J Immunol (1972) 1.26
Lymphocyte-mediated cytotoxicity against tumor cells. I. Con A activated cytotoxic effector cells exhibit immunological specificity. Cell Immunol (1975) 1.26
Mitogenic properties of the thymus-independent antigen pneumococcal polysaccharide S3. Eur J Immunol (1973) 1.26
Structure and function of three novel MHC class I antigens derived from a C3H ultraviolet-induced fibrosarcoma. J Exp Med (1986) 1.26
T cell recognition of QA-1b antigens on cells lacking a functional Tap-2 transporter. J Immunol (1992) 1.24
Immunocyte triggering. Cell Immunol (1970) 1.24
Relationship between trinitrophenyl and H-2 antigens on trinitrophenyl-modified spleen cells. I. H-2 antigens on cells treated with trinitrobenzene sulfonic acid are derivatized. J Immunol (1977) 1.23
MHC class Ib-restricted CTL provide protection against primary and secondary Listeria monocytogenes infection. J Immunol (2000) 1.23
Expression and T cell recognition of hybrid antigens with amino-terminal domains encoded by Qa-2 region of major histocompatibility complex and carboxyl termini of transplantation antigens. J Exp Med (1985) 1.23
Identification of a unique tumor-specific antigen as a novel class I major histocompatibility molecule. Proc Natl Acad Sci U S A (1985) 1.23
The role of adherent cells in B and T lymphocyte activation. Immunol Rev (1978) 1.23
Hypokalemia after hypertonic phosphate enemas. J Pediatr (1979) 1.23
Differential effect of heterologous anti-lymphocyte serum on antibody-producing cells and antigen-sensitive cells. J Immunol (1968) 1.22
Expression and function of a nonglycosylated major histocompatibility class I antigen. J Exp Med (1986) 1.22
The role of adherent cells in the immune response. Fibroblasts and products released by fibroblasts and peritoneal cells can substitute for adherent cells. Scand J Immunol (1976) 1.21
The polyclonal B-cell-activating property of protein A is not due to its interaction with the FC part of immunoglobulin receptors. Scand J Immunol (1977) 1.19
HLA-DR antigens render resting T cells sensitive to interleukin-2 and induce production of the growth factor in the autologous mixed lymphocyte reaction. Cell Immunol (1981) 1.19
Regulation of cellular antibody synthesis effect of adoptively transferred antibody-producing spleen cells on cellular antibody synthesis. J Immunol (1968) 1.19
Interleukin 4 instructs uncommitted B lymphocytes to switch to IgG1 and IgE. Eur J Immunol (1988) 1.17
Oxygen-assisted exercise in chronic obstructive lung disease. The effect on exercise capacity and arterial blood gas tensions. Am Rev Respir Dis (1978) 1.16
Linked recognition of helper and cytotoxic antigenic determinants for the generation of cytotoxic T lymphocytes. Ann N Y Acad Sci (1988) 1.15
Positive selection of self- and alloreactive CD8+ T cells in Tap-1 mutant mice. Proc Natl Acad Sci U S A (1994) 1.15
Characterization of individual tumor necrosis factor alpha-and beta-producing cells after polyclonal T cell activation. J Immunol Methods (1989) 1.14
Polyclonal B-cell activators induce immunological response to autologous serum proteins. Cell Immunol (1977) 1.13
Combination cisplatin, 5-fluorouracil and radiation therapy for locally advanced unresectable or medically unfit bladder cancer cases: a Southwest Oncology Group Study. J Urol (2001) 1.13
Dominance of a single peptide bound to the class I(B) molecule, Qa-1b. J Immunol (1997) 1.12