Published in Science on April 25, 1969
Crystal structure of human indoleamine 2,3-dioxygenase: catalytic mechanism of O2 incorporation by a heme-containing dioxygenase. Proc Natl Acad Sci U S A (2006) 1.91
Monohydroxylation of phenol and 2,5-dichlorophenol by toluene dioxygenase in Pseudomonas putida F1. Appl Environ Microbiol (1989) 1.61
Oxidation of nicotinic acid by a Bacillus species: source of oxygen atoms for the hydroxylation of nicotinic acid and 6-hydroxynicotinic acid. J Bacteriol (1971) 1.29
A monophenol oxidase activity in extracts of sorghum. Plant Physiol (1970) 1.12
Free radicals: properties, sources, targets, and their implication in various diseases. Indian J Clin Biochem (2014) 1.11
Ascorbate depletion: a critical step in nickel carcinogenesis? Environ Health Perspect (2005) 1.04
The tryptophan oxidation pathway in mosquitoes with emphasis on xanthurenic acid biosynthesis. J Insect Physiol (2006) 0.88
Relationship between properties of a series of anilines and their transformation by bacteria. Appl Environ Microbiol (1987) 0.86
Biochemical mechanisms leading to tryptophan 2,3-dioxygenase activation. Arch Insect Biochem Physiol (2007) 0.83
Oxaziridines as possible intermediates in flavin monooxygenases. Proc Natl Acad Sci U S A (1974) 0.82
Mitochondrial permeability transition induced by chemically generated singlet oxygen. J Bioenerg Biomembr (2002) 0.79
Tryptophan metabolism in micro-organisms. Biochem J (1972) 0.75
Nickel-free stainless steel avoids neointima formation following coronary stent implantation. Sci Technol Adv Mater (2012) 0.75
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Diphtheria toxin-dependent adenosine diphosphate ribosylation of aminoacyl transferase II and inhibition of protein synthesis. J Biol Chem (1968) 3.81
Complete nucleotide sequence of the metapyrocatechase gene on the TOI plasmid of Pseudomonas putida mt-2. J Biol Chem (1983) 3.81
ADP-ribosylation. Annu Rev Biochem (1985) 3.30
Poly(ADP-ribose) and ADP-ribosylation of proteins. Annu Rev Biochem (1977) 3.08
Indoleamine 2,3-dioxygenase. Purification and some properties. J Biol Chem (1978) 2.78
Metapyrocatechase. 3. Substrate specificity and mode of ring fission. Biochim Biophys Acta (1970) 2.32
Tryptophan pyrrolase of rabbit intestine. D- and L-tryptophan-cleaving enzyme or enzymes. J Biol Chem (1967) 2.27
Possible participation of superoxide anion in the intestinal tryptophan 2,3-dioxygenase reaction. J Biol Chem (1971) 2.26
Adenosine diphosphate ribosylation of aminoacyl transferase II and inhibition of protein synthesis by diphtheria toxin. J Biol Chem (1971) 2.23
Arousal effect of orexin A depends on activation of the histaminergic system. Proc Natl Acad Sci U S A (2001) 2.20
Induction of pulmonary indoleamine 2,3-dioxygenase by interferon. Proc Natl Acad Sci U S A (1981) 2.10
Studies on the polymer of adenosine diphosphate ribose. I. Enzymic formation from nicotinamide adenine dinuclotide in mammalian nuclei. J Biol Chem (1967) 2.08
The enzymatic cleavage of beta-carotene into vitamin A by soluble enzymes of rat liver and intestine. Proc Natl Acad Sci U S A (1965) 2.01
Reconstruction of the lacrimal excretory system. Plast Reconstr Surg (1992) 2.01
Allosteric properties of nucleoside diphosphatase and its identity with thiamine pyrophosphatase. J Biol Chem (1968) 1.98
Adenyl cyclase of Brevibacterium liquefaciens. Biochim Biophys Acta (1967) 1.93
New degradative routes of 5-hydroxytryptophan and serotonin by intestinal tryptophan 2,3-dioxygenase. Biochem Biophys Res Commun (1972) 1.91
Crystalline oxygenases of pseudomonads. Bacteriol Rev (1966) 1.91
Metapyrocatechase. II. The role of iron and sulfhydryl groups. J Biol Chem (1968) 1.87
Purification of prostaglandin endoperoxide synthetase from bovine vesicular gland microsomes. J Biol Chem (1976) 1.83
Poly(ADP-ribose) synthetase, a main acceptor of poly(ADP-ribose) in isolated nuclei. J Biol Chem (1981) 1.78
Studies on indoleamine 2,3-dioxygenase. I. Superoxide anion as substrate. J Biol Chem (1975) 1.72
Pathways of nicotinamide adenine dinucleotide biosynthesis in nicotinic acid or nicotinamide requiring microorganisms. Biochem Biophys Res Commun (1967) 1.72
Snake venom phosphodiesterase: simple purification with Blue Sepharose and its application to poly(ADP-ribose) study. Biochem Biophys Res Commun (1978) 1.71
Studies on pyrocatechase. I. Purification and spectral properties. J Biol Chem (1967) 1.70
Induction of indoleamine 2,3-dioxygenase in mouse lung during virus infection. Proc Natl Acad Sci U S A (1979) 1.66
Salivary prostaglandin concentrations: possible state indicators for major depression. Am J Psychiatry (1989) 1.62
Inhibition of chemiluminescent response of human polymorphonuclear leukocytes by hyperosmolality comparable to renal medulla and preservation by ofloxacin. Eur Urol (1991) 1.60
Search for supersymmetry using final states with one lepton, jets, and missing transverse momentum with the ATLAS detector in √s=7 TeV pp collisions. Phys Rev Lett (2011) 1.60
Induction of pulmonary indoleamine 2,3-dioxygenase by intraperitoneal injection of bacterial lipopolysaccharide. Proc Natl Acad Sci U S A (1978) 1.60
Biochemical, structural, genetic, physiological, and pathophysiological features of lipocalin-type prostaglandin D synthase. Biochim Biophys Acta (2000) 1.59
Tryptophan degradation in mice initiated by indoleamine 2,3-dioxygenase. J Biol Chem (1986) 1.58
Protocatechuate 3,4-dioxygenase. I. Crystallization and characterization. J Biol Chem (1968) 1.57
Histopathological examination of two cases of anterior staphyloma associated with Peters' anomaly and persistent hyperplastic primary vitreous. Br J Ophthalmol (2001) 1.57
Prostaglandin D synthase: structure and function. Vitam Horm (2000) 1.56
Cloning and crystal structure of hematopoietic prostaglandin D synthase. Cell (1997) 1.55
Enzymic adenosine diphosphoribosylation of nuclear proteins. Cold Spring Harb Symp Quant Biol (1969) 1.54
On the submitochondrial localization of l-kynurenine-3-hydroxylase. Biochem Biophys Res Commun (1967) 1.53
Natural occurrence of poly(ADP-ribosyl) histones in rat liver. Proc Natl Acad Sci U S A (1975) 1.52
Extradiol cleavage of 3-substituted catechols by an intradiol dioxygenase, pyrocatechase, from a Pseudomonad. J Biol Chem (1975) 1.51
Cytokeratins 8 and 19 in the mouse placental development. J Cell Biol (2000) 1.49
Reconstruction of perianal skin defect using a V-Y advancement of bilateral gluteus maximus musculocutaneous flaps: reconstruction considering anal cleft and anal function. Br J Plast Surg (1999) 1.46
Enzymic adenosine diphosphate ribosylation of histone and poly adenosine diphosphate ribose synthesis in rat liver nuclei. J Biol Chem (1968) 1.45
A rare variant of the radial artery: clinical considerations in raising a radial forearm flap. Br J Plast Surg (2000) 1.45
Prostaglandin D2 in rat brain, spinal cord and pituitary: basal level and regional distribution. Life Sci (1982) 1.44
Regulation of biodegradative threonine deaminase synthesis in Escherichia coli by cyclic adenosine 3',5'-monophosphate. J Biol Chem (1970) 1.43
Purification and some properties of protocatechuate 4,5-dioxygenase. Biochim Biophys Acta (1970) 1.43
Observation of a centrality-dependent dijet asymmetry in lead-lead collisions at sqrt[S(NN)] =2.76 TeV with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.41
Lack of tactile pain (allodynia) in lipocalin-type prostaglandin D synthase-deficient mice. Proc Natl Acad Sci U S A (1999) 1.41
Efficacy of selective venous sampling to localize a small ovarian androgen-producing tumor. J Obstet Gynaecol Res (1999) 1.41
Cytotoxic cells directed against placental cells detected in human habitual abortions by an in vitro terminal labeling assay. Am J Reprod Immunol (1994) 1.41
Identification and characterization of a new plasmid carrying genes for degradation of 2,4-dichlorophenoxyacetate from Pseudomonas cepacia CSV90. Appl Environ Microbiol (1994) 1.39
Structural similarity of bovine lung prostaglandin F synthase to lens epsilon-crystallin of the European common frog. Proc Natl Acad Sci U S A (1988) 1.39
Measurement of dijet azimuthal decorrelations in pp collisions at sqrt(s)=7 TeV. Phys Rev Lett (2011) 1.39
Biochemical and immunological characterization of rat spleen prostaglandin D synthetase. J Biol Chem (1987) 1.39
Prostaglandin D2 formation and characterization of its synthetases in various tissues of adult rats. Arch Biochem Biophys (1988) 1.39
ADP-ribosylation of histone H1. Identification of glutamic acid residues 2, 14, and the COOH-terminal lysine residue as modification sites. J Biol Chem (1980) 1.38
Role of prostaglandin D2 in the hypothermia of rats caused by bacterial lipopolysaccharide. Proc Natl Acad Sci U S A (1982) 1.37
Oxygenases and dioxygenases. Top Curr Chem (1979) 1.37
Cleavage of pyrogallol by non-heme iron-containing dioxygenases. J Biol Chem (1980) 1.37
Regulation of indoleamine 2,3-dioxygenase activity in the small intestine and the epididymis of mice. Arch Biochem Biophys (1980) 1.36
Regulation of biodegradative threonine deaminase. Curr Top Cell Regul (1976) 1.35
Purification and characterization of rat brain prostaglandin D synthetase. J Biol Chem (1985) 1.35
Adenylate cyclase from Brevibacterium liquefaciens. I. Purification, crystallization, and some properties. J Biol Chem (1974) 1.35
Prostaglandin D2, a cerebral sleep-inducing substance in rats. Proc Natl Acad Sci U S A (1983) 1.35
Determination of the strange-quark density of the proton from ATLAS measurements of the W→ℓν and Z→ℓℓ cross sections. Phys Rev Lett (2012) 1.34
Search for new particles in two-jet final states in 7 TeV proton-proton collisions with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.32
Prostaglandin D2 induces sleep when microinjected into the preoptic area of conscious rats. Biochem Biophys Res Commun (1982) 1.31
Purification, subunit structure, and partial amino acid sequence of metapyrocatechase. J Biol Chem (1983) 1.31
Prostaglandin hydroperoxidase, an integral part of prostaglandin endoperoxide synthetase from bovine vesicular gland microsomes. J Biol Chem (1979) 1.29
A germ cell-specific nuclear antigen recognized by a monoclonal antibody raised against mouse testicular germ cells. Int J Androl (1997) 1.29
Studies on the biosynthesis of nicotinamide adenine dinucleotide. 3. Comparative in vivo studies on nicotinic acid, nicotinamide, and quinolinic acid as precursors of nicotinamide adenine dinucleotide. J Biol Chem (1966) 1.27
Observation of associated near-side and away-side long-range correlations in sqrt[s(NN)]=5.02 TeV proton-lead collisions with the ATLAS detector. Phys Rev Lett (2013) 1.27
Identification and characterization of a haploid germ cell-specific nuclear protein kinase (Haspin) in spermatid nuclei and its effects on somatic cells. J Biol Chem (1999) 1.27
The oxygenated form of L-tryptophan 2,3-dioxygenase as reaction intermediate. J Biol Chem (1970) 1.26
Identification and characterization of testis specific ornithine decarboxylase antizyme (OAZ-t) gene: expression in haploid germ cells and polyamine-induced frameshifting. Genes Cells (2000) 1.26
Poly ADP-ribose glycohydrolase from rat liver nuclei, a novel enzyme degrading the polymer. Biochem Biophys Res Commun (1972) 1.25
Isolation and characterization of cDNA clones specifically expressed in testicular germ cells. FEBS Lett (1994) 1.25
Indoleamine 2,3-dioxygenase: incorporation of 18O2-- and 18O2 into the reaction products. J Biol Chem (1977) 1.23
Crystalline L-lysine oxygenase. J Biol Chem (1966) 1.23
Occurrence of 9-deoxy-delta 9,delta 12-13,14-dihydroprostaglandin D2 in human urine. J Biol Chem (1988) 1.23
In vitro and in vivo formation of two new metabolites of melatonin. J Biol Chem (1974) 1.22
Prostaglandin D2-sensitive, sleep-promoting zone defined in the ventral surface of the rostral basal forebrain. Proc Natl Acad Sci U S A (1994) 1.22
Prostaglandin synthetase system--resolution into oxygenase and isomerase components. Proc Natl Acad Sci U S A (1974) 1.21
ADP-ribosyl protein lyase. Purification, properties, and identification of the product. J Biol Chem (1984) 1.21
Dominant expression of mRNA for prostaglandin D synthase in leptomeninges, choroid plexus, and oligodendrocytes of the adult rat brain. Proc Natl Acad Sci U S A (1993) 1.21
D-amino-acid oxidase is confined to the lower brain stem and cerebellum in rat brain: regional differentiation of astrocytes. Brain Res (1994) 1.20
An archetypical extradiol-cleaving catecholic dioxygenase: the crystal structure of catechol 2,3-dioxygenase (metapyrocatechase) from Ppseudomonas putida mt-2. Structure (1999) 1.20
Lipocalin-type prostaglandin D synthase (beta-trace) is a newly recognized type of retinoid transporter. J Biol Chem (1997) 1.20
Prostate-specific transcription factor hPSE is translated only in normal prostate epithelial cells. Cancer Res (2000) 1.20
The endogenous somnogen adenosine excites a subset of sleep-promoting neurons via A2A receptors in the ventrolateral preoptic nucleus. Neuroscience (2005) 1.20
An adenosine A2a agonist increases sleep and induces Fos in ventrolateral preoptic neurons. Neuroscience (2001) 1.20
Search for dark matter candidates and large extra dimensions in events with a photon and missing transverse momentum in pp collision data at sqrt[s]=7 TeV with the ATLAS detector. Phys Rev Lett (2013) 1.19