Published in Nature on January 10, 1970
Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose. Proc Natl Acad Sci U S A (1972) 83.88
Protein synthesis directed by encephalomyocarditis virus RNA: properties of a transfer RNA-dependent system. Proc Natl Acad Sci U S A (1971) 6.52
Synthesis of and chains of rabbit hemoglobin in a cell-free extract from Krebs II ascites cells. Proc Natl Acad Sci U S A (1971) 5.92
Translation of reovirus messenger RNAs synthetesized in vitro into reovirus polypeptides by several mammalian cell-free extracts. Proc Natl Acad Sci U S A (1972) 2.69
Characterization of the polypeptides formed in response to encephalomyocarditis virus ribonucleic acid in a cell-free system from mouse ascites tumor cells. J Virol (1972) 2.23
Simple method for the isolation of encephalomyocarditis virus ribonucleic acid. J Virol (1972) 1.76
Virus protein synthesis in animal cell-free systems: nature of the products synthesized in resonse to ribonucleic acid of encephalomyocarditis virus. J Virol (1971) 1.69
Cell-free synthesis of rat growth hormone. Proc Natl Acad Sci U S A (1973) 1.67
Synthesis of capsid and noncapsid viral proteins in response to encephalomyocarditis virus ribonucleic acid in animal cell-free systems. J Virol (1971) 1.30
Protein synthesis in cell-free systems: an effect of interferon. J Virol (1971) 1.29
Gene activation in somatic nuclei after injection into amphibian oocytes. Proc Natl Acad Sci U S A (1977) 1.10
Cell-free translation of maternal messenger RNA from sea urchin eggs. Proc Natl Acad Sci U S A (1973) 1.09
Translation of encephalomyocarditis viral RNA in oocytes of Xenopus laevis. Proc Natl Acad Sci U S A (1972) 1.08
Methionine transfer ribonucleic acids of avian myeloblastosis virus. Proc Natl Acad Sci U S A (1973) 0.98
In vitro translation of oogenetic messenger RNA of sea urchin eggs and picornavirus RNA with a cell-free system from sarcoma 180. Proc Natl Acad Sci U S A (1973) 0.75
A short amino acid sequence able to specify nuclear location. Cell (1984) 21.17
A possible precursor of immunoglobulin light chains. Nat New Biol (1972) 11.03
The isolation and properties of the monoglucuronides of stilboestrol, hexoestrol and dienoestrol. Biochem J (1948) 10.61
Sequence requirements for nuclear location of simian virus 40 large-T antigen. Nature (1984) 10.52
Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis. Cell (1990) 9.21
Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive. Nature (1992) 8.47
Polyoma virus transforming protein associates with the product of the c-src cellular gene. Nature (1983) 7.20
Organization and expression of early genes of simian virus 40. Proc Natl Acad Sci U S A (1978) 7.10
Transcription elongation factor P-TEFb is required for HIV-1 tat transactivation in vitro. Genes Dev (1997) 6.88
Functional identity of proliferating cell nuclear antigen and a DNA polymerase-delta auxiliary protein. Nature (1987) 6.45
Translation of globin messenger RNA in a heterologous cell-free system. Nature (1971) 6.29
Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis. Cell (1993) 6.25
HIV-1 Tat protein increases transcriptional initiation and stabilizes elongation. Cell (1989) 6.11
Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src. Cell (1987) 5.84
Demonstration that CFTR is a chloride channel by alteration of its anion selectivity. Science (1991) 5.82
The gene for polypeptide IX of adenovirus type 2 and its unspliced messenger RNA. Cell (1980) 5.80
Nuclear location signals in polyoma virus large-T. Cell (1986) 5.74
The cell-cycle regulated proliferating cell nuclear antigen is required for SV40 DNA replication in vitro. Nature (1987) 4.43
Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells. Nature (1990) 4.26
Multiple functional domains in the adenovirus E1A gene. Cell (1987) 4.22
Interactions between double-stranded RNA regulators and the protein kinase DAI. Mol Cell Biol (1992) 4.16
Protein kinase activity associated with polyoma virus middle T antigen in vitro. Cell (1979) 3.78
Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel. Cell (1991) 3.75
The complex of polyoma virus middle-T antigen and pp60c-src. EMBO J (1984) 3.57
Identification of separate domains in the adenovirus E1A gene for immortalization activity and the activation of virus early genes. Mol Cell Biol (1986) 3.52
In vitro mutagenesis of a putative DNA binding domain of SV40 large-T. Virology (1984) 3.50
Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis. Cell (1993) 3.47
Generation of cAMP-activated chloride currents by expression of CFTR. Science (1991) 3.45
Structure of genes for virus-associated RNAI and RNAII of adenovirus type 2. Proc Natl Acad Sci U S A (1980) 3.45
Identity of the proliferating cell nuclear antigen and cyclin. Nature (1984) 3.44
Mutations in CFTR associated with mild-disease-form Cl- channels with altered pore properties. Nature (1993) 3.43
A mechanism for the control of protein synthesis by adenovirus VA RNAI. Cell (1986) 3.43
Control of adenovirus early gene expression: a class of immediate early products. Cell (1980) 3.41
Identification of the gene and mRNA for the adenovirus terminal protein precursor. Cell (1981) 3.39
Characterization of different tumor antigens present in cells transformed by simian virus 40. Cell (1979) 3.26
Nucleoside triphosphates are required to open the CFTR chloride channel. Cell (1991) 3.21
DNA replication and the early to late transition in adenovirus infection. Cell (1980) 3.17
The role of N-formyl-methionyl-sRNA in protein biosynthesis. J Mol Biol (1966) 3.16
Cytoplasmic methionine transfer RNAs from eukaryotes. Nature (1970) 3.12
Expression and characterization of the cystic fibrosis transmembrane conductance regulator. Nature (1990) 3.09
The human ubiquitin multigene family: some genes contain multiple directly repeated ubiquitin coding sequences. EMBO J (1985) 3.06
Large and small tumor antigens from simian virus 40 have identical amino termini mapping at 0.65 map units. Proc Natl Acad Sci U S A (1978) 3.00
A new species of virus-coded low molecular weight RNA from cells infected with adenovirus type 2. Cell (1976) 3.00
Interaction between VA RNA and the lupus antigen La: formation of a ribonucleoprotein particle in vitro. Proc Natl Acad Sci U S A (1982) 2.83
The effect of protein context on nuclear location signal function. Cell (1987) 2.83
Nucleotide sequence of N-formyl-methionyl-transfer RNA. Nature (1968) 2.82
Regulation of a protein synthesis initiation factor by adenovirus virus-associated RNA. Nature (1985) 2.80
Proteins and messenger RNAs of the transforming region of wild-type and mutant adenoviruses. J Mol Biol (1980) 2.73
Myositis autoantibody inhibits histidyl-tRNA synthetase: a model for autoimmunity. Nature (1983) 2.71
Two RNA-binding motifs in the double-stranded RNA-activated protein kinase, DAI. Genes Dev (1992) 2.70
Cell-free translation of virion RNA from nondefective and transformation-defective Rous sarcoma viruses. J Virol (1976) 2.68
Gene probe analysis of soil microbial populations selected by amendment with 2,4-dichlorophenoxyacetic acid. Appl Environ Microbiol (1992) 2.66
The primary structures of two leghemoglobin genes from soybean. Nucleic Acids Res (1982) 2.64
Monomer molecular weight of T antigen from simian virus 40-infected and transformed cells. Proc Natl Acad Sci U S A (1976) 2.64
The nucleotide sequences of two leghemoglobin genes from soybean. Nucleic Acids Res (1982) 2.60
Translational control by adenovirus: lack of virus-associated RNAI during adenovirus infection results in phosphorylation of initiation factor eIF-2 and inhibition of protein synthesis. Proc Natl Acad Sci U S A (1985) 2.53
Extraction and fingerprint analysis of simian virus 40 large and small T-antigens. J Virol (1978) 2.50
Purification and activation of the double-stranded RNA-dependent eIF-2 kinase DAI. Mol Cell Biol (1989) 2.48
Proteins binding to duplexed RNA: one motif, multiple functions. Trends Biochem Sci (2000) 2.47
Autophosphorylation in the activation loop is required for full kinase activity in vivo of human and yeast eukaryotic initiation factor 2alpha kinases PKR and GCN2. Mol Cell Biol (1998) 2.39
Different functional domains of the adenovirus E1A gene are involved in regulation of host cell cycle products. Mol Cell Biol (1987) 2.38
Molecular cloning of human gastrin cDNA: evidence for evolution of gastrin by gene duplication. Proc Natl Acad Sci U S A (1983) 2.35
Regulation of proliferating cell nuclear antigen during the cell cycle. J Biol Chem (1989) 2.33
Genes for VA-RNA in adenovirus 2. Cell (1975) 2.32
Cell-free synthesis of simian virus 40 T-antigens. J Virol (1978) 2.32
Ribosome-catalysed reaction of puromycin with a formylmethionine-containing oligonucleotide. J Mol Biol (1967) 2.31
Synergy between HIV-1 Tat and adenovirus E1A is principally due to stabilization of transcriptional elongation. Genes Dev (1990) 2.30
Binding of adenovirus VA RNA to mRNA: a possible role in splicing? Nature (1980) 2.28
Expanded CUG repeat RNAs form hairpins that activate the double-stranded RNA-dependent protein kinase PKR. RNA (2000) 2.25
Maturation and function of cystic fibrosis transmembrane conductance regulator variants bearing mutations in putative nucleotide-binding domains 1 and 2. Mol Cell Biol (1991) 2.25
Peptide antibodies to the human c-fyn gene product demonstrate pp59c-fyn is capable of complex formation with the middle-T antigen of polyomavirus. EMBO J (1988) 2.25
Purification of an adenovirus-coded DNA polymerase that is required for initiation of DNA replication. Cell (1982) 2.22
Concomitance of psoriasis and atopic dermatitis. Dermatology (1992) 2.18
Molecular and cellular effects of heat-shock and related treatments of mammalian tissue-culture cells. Cold Spring Harb Symp Quant Biol (1982) 2.18
Double-stranded-RNA-dependent protein kinase and TAR RNA-binding protein form homo- and heterodimers in vivo. Proc Natl Acad Sci U S A (1995) 2.17
Cyclic stretching stimulates synthesis of matrix components by arterial smooth muscle cells in vitro. Science (1976) 2.17
The interaction of collagen and acid mucopolysaccharides. A model for connective tissue. Biochem J (1965) 2.15
Transcriptional but not translational regulation of HIV-1 by the tat gene product. Nature (1988) 2.15
Lytic and transforming functions of individual products of the adenovirus E1A gene. J Virol (1986) 2.14
The nuclear location signal. Proc R Soc Lond B Biol Sci (1985) 2.14
Sodium ions and the shut-off of host cell protein synthesis by picornaviruses. Nature (1977) 2.12
HIV-1 Tat overcomes inefficient transcriptional elongation in vitro. J Mol Biol (1993) 2.12
PEGylation of adenovirus with retention of infectivity and protection from neutralizing antibody in vitro and in vivo. Hum Gene Ther (1999) 2.11
Coding response of N-fromyl-methionyl-sRNA to UUG. Nature (1965) 2.10
Effect of deleting the R domain on CFTR-generated chloride channels. Science (1991) 2.09
Synthesis of a structural adenovirus polypeptide in the absence of viral DNA replication. Virology (1978) 2.09
Interaction of a nodule specific, trans-acting factor with distinct DNA elements in the soybean leghaemoglobin Ibc(3) 5' upstream region. EMBO J (1988) 2.07
Characterization of the double-stranded RNA implicated in the inhibition of protein synthesis in cells infected with a mutant adenovirus defective for VA RNA. Virology (1988) 2.06
Adenovirus type 2 early proteins: assignment of the early region 1A proteins synthesized in vivo and in vitro to specific mRNAs. Virology (1981) 2.04
Polypeptidyl-sigma-ribonucleic acid and amino-acyl-sigma-ribonucleic acid binding sites on ribosomes. Nature (1966) 2.02
La antigen recognizes and binds to the 3'-oligouridylate tail of a small RNA. Mol Cell Biol (1984) 1.97
Soybean nodulin 26 is homologous to the major intrinsic protein of the bovine lens fiber membrane. Nucleic Acids Res (1988) 1.94
Localization of cystic fibrosis transmembrane conductance regulator in chloride secretory epithelia. J Clin Invest (1992) 1.93
N-formylmethionyl transfer RNA in mitochondria from yeast and rat liver. J Mol Biol (1968) 1.93
The size of Rous sarcoma virus mRNAs active in cell-free translation. Nature (1977) 1.92
The initiation of protein synthesis directed by the RNA from encephalomyocarditis virus. Eur J Biochem (1973) 1.91
Deletion loop mutagenesis: a novel method for the construction of point mutations using deletion mutants. Nucleic Acids Res (1982) 1.90