Published in Biochim Biophys Acta on April 21, 1972
Role of collagenous matrices in the adhesion and growth of cells. J Cell Biol (1981) 5.60
Monovalent ionophores inhibit secretion of procollagen and fibronectin from cultured human fibroblasts. Proc Natl Acad Sci U S A (1979) 1.99
Effects of antimicrotubular agents on the secretion of collagen. A biochemical and morphological study. J Cell Biol (1974) 1.93
Type VI collagen in extracellular, 100-nm periodic filaments and fibrils: identification by immunoelectron microscopy. J Cell Biol (1986) 1.55
Ferritin-conjugated antibodies used for labeling of organelles involved in the cellular synthesis and transport of procollagen. Proc Natl Acad Sci U S A (1974) 1.42
The route of secretion of procollagen. The influence of alphaalpha'-bipyridyl, colchicine and antimycin A on the secretory process in embryonic-chick tendon and cartilage cells. Biochem J (1976) 1.23
The assembly of tetrameric prolyl hydroxylase in tendon fibroblasts from newly synthesized alpha-subunits and from preformed cross-reacting protein. Biochem J (1980) 1.01
Translation of embryonic-chick tendon procollagen messenger ribonucleic acid in two cell-free protein-synthesizing systems. Biochem J (1979) 1.01
Collagen biosynthesis. Characterization of subcellular fractions from embyonic chick fibroblasts and the intracellular localization of protocollagen prolyl and protocollagen lysyl hydroxylases. Biochem J (1974) 0.99
Metabolism of rabbit skin collagen. Differences in the apparent turnover rates of type-I- and type-III-collagen precursors determined by constant intravenous infusion of labelled amino acids. Biochem J (1979) 0.99
The synthesis and secretion of cartilage procollagen. Biochem J (1975) 0.93
Effect of L-azetidine-2-carboxylic acid on glycosylations of collagen in chick-embryo tendon cells. Biochem J (1976) 0.87
Purification of human procollagen type III N-proteinase from placenta and preparation of antiserum. Biochem J (1986) 0.85
Intracellular processing of procollagen induced by the action of colchicine. J Anat (1980) 0.83
Supramolecular assemblies of mRNA direct the coordinated synthesis of type I procollagen chains. Proc Natl Acad Sci U S A (1985) 0.83
Detection and partial characterization of a chymostatin-sensitive endopeptidase in transformed fibroblasts. Proc Natl Acad Sci U S A (1983) 0.82
Studies on enzymes of collagen biosynthesis and the synthesis of hydroxyproline in macrophages and mast cells. Biochem J (1979) 0.80
Synthesis of procollagen by matrix-free cells from embryonic-chick arteries. Biochem J (1977) 0.79
The subcellular fractionation of embryonic chick tendon and cartilage cells: a re-examination. Biochem J (1979) 0.77
The "spindle-shaped" body in fibroblasts: intracellular collagen fibrils. J Anat (1981) 0.77
Labelling of prolyl hydroxylase tetrameric subunits in freshly isolated chick-embryo tendon cells and in certain chick-embryo tissues in vivo. Biochem J (1982) 0.75
Successful Treatment of Scleredema Diabeticorum by Combining Local PUVA and Colchicine: A Case Report. Case Rep Dermatol (2012) 0.75
The effects of colchicine and its derivates on the collagen biosynthesis in vitro. Agents Actions (1977) 0.75
Catalytic properties of lysyl hydroxylase from cells synthesizing genetically different collagen types. Biochem J (1982) 0.75
Effect of prevention of procollagen triple-helix formation on proline 3-hydroxylation in freshly isolated chick-embryo tendon cells. Biochem J (1981) 0.75
Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta. Nat Med (1999) 9.73
Adult rat and human bone marrow stromal cells differentiate into neurons. J Neurosci Res (2000) 7.87
Modifications of a specific assay for hydroxyproline in urine. Anal Biochem (1967) 5.48
Conformation-sensitive gel electrophoresis for rapid detection of single-base differences in double-stranded PCR products and DNA fragments: evidence for solvent-induced bends in DNA heteroduplexes. Proc Natl Acad Sci U S A (1993) 5.47
Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains. Proc Natl Acad Sci U S A (1999) 5.20
Modified procedure for the assay of H-3-or C-14-labeled hydroxyproline. Anal Biochem (1966) 5.08
Rapid expansion of recycling stem cells in cultures of plastic-adherent cells from human bone marrow. Proc Natl Acad Sci U S A (2000) 4.72
Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage, and lung in irradiated mice. Proc Natl Acad Sci U S A (1995) 4.47
Heritable diseases of collagen. N Engl J Med (1984) 4.39
Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats--similarities to astrocyte grafts. Proc Natl Acad Sci U S A (1998) 4.13
Propagation and senescence of human marrow stromal cells in culture: a simple colony-forming assay identifies samples with the greatest potential to propagate and differentiate. Br J Haematol (1999) 4.08
Identification of a subpopulation of rapidly self-renewing and multipotential adult stem cells in colonies of human marrow stromal cells. Proc Natl Acad Sci U S A (2001) 4.07
The biosynthesis of collagen and its disorders (first of two parts). N Engl J Med (1979) 3.87
Two improved methods for preparing ferritin-protein conjugates for electron microscopy. J Cell Biol (1975) 3.81
Plastic adherent stromal cells from the bone marrow of commonly used strains of inbred mice: variations in yield, growth, and differentiation. J Cell Biochem (1999) 3.75
Marrow stromal cells as a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperfecta. Proc Natl Acad Sci U S A (1998) 3.17
Cloning a cDNA for the pro-alpha 2 chain of human type I collagen. Proc Natl Acad Sci U S A (1981) 2.97
Mutations in collagen genes: causes of rare and some common diseases in humans. FASEB J (1991) 2.86
Single base mutation in the type II procollagen gene (COL2A1) as a cause of primary osteoarthritis associated with a mild chondrodysplasia. Proc Natl Acad Sci U S A (1990) 2.79
The biosynthesis of collagen and its disorders (second of two parts). N Engl J Med (1979) 2.76
Internal deletion in a collagen gene in a perinatal lethal form of osteogenesis imperfecta. Nature (1983) 2.73
The thermal transition of a non-hydroxylated form of collagen. Evidence for a role for hydroxyproline in stabilizing the triple-helix of collagen. Biochem Biophys Res Commun (1973) 2.66
Clinical responses to bone marrow transplantation in children with severe osteogenesis imperfecta. Blood (2001) 2.65
Radial packing, order, and disorder in collagen fibrils. Biophys J (1995) 2.60
Restriction fragment length polymorphism associated with the pro alpha 2(I) gene of human type I procollagen. Application to a family with an autosomal dominant form of osteogenesis imperfecta. J Clin Invest (1983) 2.50
Nucleotide sequences of complementary deoxyribonucleic acids for the pro alpha 1 chain of human type I procollagen. Statistical evaluation of structures that are conserved during evolution. Biochemistry (1983) 2.42
Structure of a cDNA for the pro alpha 2 chain of human type I procollagen. Comparison with chick cDNA for pro alpha 2(I) identifies structurally conserved features of the protein and the gene. Biochemistry (1983) 2.41
The zipper-like folding of collagen triple helices and the effects of mutations that disrupt the zipper. Annu Rev Biophys Biophys Chem (1991) 2.33
Structure of a full-length cDNA clone for the prepro alpha 2(I) chain of human type I procollagen. Comparison with the chicken gene confirms unusual patterns of gene conservation. Biochem J (1988) 2.30
cDNA clones coding for the pro-alpha1(IV) chain of human type IV procollagen reveal an unusual homology of amino acid sequences in two halves of the carboxyl-terminal domain. J Biol Chem (1985) 2.30
Osteogenesis imperfecta: cloning of a pro-alpha 2(I) collagen gene with a frameshift mutation. J Biol Chem (1984) 2.25
Stop codon in the procollagen II gene (COL2A1) in a family with the Stickler syndrome (arthro-ophthalmopathy). Proc Natl Acad Sci U S A (1991) 2.24
Proteolytic enzymes as probes for the triple-helical conformation of procollagen. Anal Biochem (1981) 2.19
In vitro differentiation of human marrow stromal cells into early progenitors of neural cells by conditions that increase intracellular cyclic AMP. Biochem Biophys Res Commun (2001) 2.17
Donor variation in the growth properties and osteogenic potential of human marrow stromal cells. J Cell Biochem (1999) 2.17
Conformation sensitive gel electrophoresis for simple and accurate detection of mutations: comparison with denaturing gradient gel electrophoresis and nucleotide sequencing. Proc Natl Acad Sci U S A (1998) 2.14
Synthesis of a shortened pro-alpha 2(I) chain and decreased synthesis of pro-alpha 2(I) chains in a proband with osteogenesis imperfecta. J Biol Chem (1983) 2.03
Human Ehlers-Danlos syndrome type VII C and bovine dermatosparaxis are caused by mutations in the procollagen I N-proteinase gene. Am J Hum Genet (1999) 1.98
Assignment of the human pro alpha 2(I) collagen structural gene (COLIA2) to chromosome 7 by molecular hybridization. Am J Hum Genet (1982) 1.98
Folding mechanism of the triple helix in type-III collagen and type-III pN-collagen. Role of disulfide bridges and peptide bond isomerization. Eur J Biochem (1980) 1.96
Intra-articular injection of human mesenchymal stem cells (MSCs) promote rat meniscal regeneration by being activated to express Indian hedgehog that enhances expression of type II collagen. Osteoarthritis Cartilage (2012) 1.96
Genetic linkage of a polymorphism in the type II procollagen gene (COL2A1) to primary osteoarthritis associated with mild chondrodysplasia. N Engl J Med (1990) 1.93
Splicing mutations of 54-bp exons in the COL11A1 gene cause Marshall syndrome, but other mutations cause overlapping Marshall/Stickler phenotypes. Am J Hum Genet (1999) 1.88
Transgenic mice with targeted inactivation of the Col2 alpha 1 gene for collagen II develop a skeleton with membranous and periosteal bone but no endochondral bone. Genes Dev (1995) 1.86
An allele of COL9A2 associated with intervertebral disc disease. Science (1999) 1.85
Rat marrow stromal cells are more sensitive to plating density and expand more rapidly from single-cell-derived colonies than human marrow stromal cells. Stem Cells (2001) 1.84
Mutations in COL11A2 cause non-syndromic hearing loss (DFNA13). Nat Genet (1999) 1.82
BMP-6 enhances chondrogenesis in a subpopulation of human marrow stromal cells. Biochem Biophys Res Commun (2001) 1.80
A transport form of collagen from embryonic tendon: electron microscopic demonstration of an NH 2 -terminal extension and evidence suggesting the presence of cystine in the molecule (chick embryo-tropocollagen-gel filtration). Proc Natl Acad Sci U S A (1972) 1.79
Human type I procollagen genes are located on different chromosomes. Proc Natl Acad Sci U S A (1982) 1.78
Type I procollagen carboxyl-terminal proteinase from chick embryo tendons. Purification and characterization. J Biol Chem (1985) 1.71
Synthesis and processing of a type I procollagen containing shortened pro-alpha 1(I) chains by fibroblasts from a patient with osteogenesis imperfecta. J Biol Chem (1983) 1.71
Evidence for a structural mutation of procollagen type I in a patient with the Ehlers-Danlos syndrome type VII. J Biol Chem (1980) 1.69
Further evidence for a transport form of collagen. Its extrusion and extracellular conversion to tropocollagen in embryonic tendon. FEBS Lett (1971) 1.66
Collagen fibrils in vitro grow from pointed tips in the C- to N-terminal direction. Biochem J (1990) 1.66
Molecular heterogeneity in the mild autosomal dominant forms of osteogenesis imperfecta. Am J Hum Genet (1984) 1.62
Enzymatic hydroxylation of proline and lysine in protocollagen. Proc Natl Acad Sci U S A (1967) 1.61
The biosynthesis of collagen. 1. N Engl J Med (1972) 1.61
Affinity column purification of protocollagen proline hydroxylase from chick embryos and further characterization of the enzyme. J Biol Chem (1973) 1.58
A mutation in the gene for type III procollagen (COL3A1) in a family with aortic aneurysms. J Clin Invest (1990) 1.57
The clinical features of homozygous alpha 2(I) collagen deficient osteogenesis imperfecta. J Med Genet (1984) 1.56
Hydroxylation of proline and the intracellular accumulation of a polypeptide precursor of collagen. Science (1966) 1.54
Single base mutation in the type III procollagen gene that converts the codon for glycine 883 to aspartate in a mild variant of Ehlers-Danlos syndrome IV. J Biol Chem (1989) 1.53
The molecular defect in a nonlethal variant of osteogenesis imperfecta. Synthesis of pro-alpha 2(I) chains which are not incorporated into trimers of type I procollagen. J Biol Chem (1983) 1.52
The biosynthesis of collagen. 3. N Engl J Med (1972) 1.52
A substitution of cysteine for glycine 748 of the alpha 1 chain produces a kink at this site in the procollagen I molecule and an altered N-proteinase cleavage site over 225 nm away. J Biol Chem (1988) 1.51
Proline analogue removes fibroblasts from cultured mixed cell populations. Nature (1977) 1.44
Genetic linkage analysis of hereditary arthro-ophthalmopathy (Stickler syndrome) and the type II procollagen gene. Am J Hum Genet (1989) 1.44
The biosynthesis of basement membrane collagen in embryonic chick lens. I. Delay between the synthesis of polypeptide chains and the secretion of collagen by matrix-free cells. J Biol Chem (1972) 1.44
Formation of collagen fibrils in vitro by cleavage of procollagen with procollagen proteinases. J Biol Chem (1982) 1.44
A rapid and simple PCR-based method for isolation of cDNAs from differentially expressed genes. Nucleic Acids Res (1994) 1.43
Ferritin-conjugated antibodies used for labeling of organelles involved in the cellular synthesis and transport of procollagen. Proc Natl Acad Sci U S A (1974) 1.42
Collagen synthesis: localization of prolyl hydroxylase in tendon cells detected with ferritin-labeled antibodies. Science (1973) 1.41
A point mutation in a type I procollagen gene converts glycine 748 of the alpha 1 chain to cysteine and destabilizes the triple helix in a lethal variant of osteogenesis imperfecta. J Biol Chem (1987) 1.41
The C-proteinase that processes procollagens to fibrillar collagens is identical to the protein previously identified as bone morphogenic protein-1. Proc Natl Acad Sci U S A (1996) 1.41
Partial isodisomy for maternal chromosome 7 and short stature in an individual with a mutation at the COL1A2 locus. Am J Hum Genet (1992) 1.40
cDNA cloning and expression of bovine procollagen I N-proteinase: a new member of the superfamily of zinc-metalloproteinases with binding sites for cells and other matrix components. Proc Natl Acad Sci U S A (1997) 1.39
A single base mutation that substitutes serine for glycine 790 of the alpha 1 (III) chain of type III procollagen exposes an arginine and causes Ehlers-Danlos syndrome IV. J Biol Chem (1989) 1.39
Synthesis of an altered type III procollagen in a patient with type IV Ehlers-Danlos syndrome. A structural change in the alpha 1(III) chain which makes the protein more susceptible to proteinases. J Biol Chem (1985) 1.39
Assembly of type I collagen fibrils de novo. Between 37 and 41 degrees C the process is limited by micro-unfolding of monomers. J Biol Chem (1988) 1.38
Expression of a partially deleted gene of human type II procollagen (COL2A1) in transgenic mice produces a chondrodysplasia. Proc Natl Acad Sci U S A (1991) 1.38
Synthesis of (Pro-Hyp-Gly) n of defined molecular weights. Evidence for the stabilization of collagen triple helix by hydroxypyroline. Biochim Biophys Acta (1973) 1.37
A defect in the structure of type I procollagen in a patient who had osteogenesis imperfecta: excess mannose in the COOH-terminal propeptide. Proc Natl Acad Sci U S A (1980) 1.36
Thermal stability of type I and type III procollagens from normal human fibroblasts and from a patient with osteogenesis imperfecta. Proc Natl Acad Sci U S A (1980) 1.36
The structural genes for alpha 1 and alpha 2 chains of human type IV collagen are divergently encoded on opposite DNA strands and have an overlapping promoter region. J Biol Chem (1988) 1.35
Formation of interchain disulfide bonds and helical structure during biosynthesis of procollagen by embryonic tendon cells. Biochemistry (1974) 1.33
Growing tips of type I collagen fibrils formed in vitro are near-paraboloidal in shape, implying a reciprocal relationship between accretion and diameter. Proc Natl Acad Sci U S A (1992) 1.33
Kinetics for the secretion of procollagen by freshly isolated tendon cells. J Biol Chem (1977) 1.32
First-stage autosomal genome screen in extended pedigrees suggests genes predisposing to low bone mineral density on chromosomes 1p, 2p and 4q. Eur J Hum Genet (1998) 1.32
Structure of cDNA clones coding for human type II procollagen. The alpha 1(II) chain is more similar to the alpha 1(I) chain than two other alpha chains of fibrillar collagens. Biochem J (1989) 1.31
Mutation in a gene for type I procollagen (COL1A2) in a woman with postmenopausal osteoporosis: evidence for phenotypic and genotypic overlap with mild osteogenesis imperfecta. Proc Natl Acad Sci U S A (1991) 1.31
Biosynthesis of cartilage procollagen. Eur J Biochem (1973) 1.30