Published in Br J Pharmacol on June 01, 1972
Acid secretion by guinea-pig isolated stomach. J Physiol (1976) 1.78
The action of aminophylline on the acutely transplanted dog heart: effect of alpha- and beta-adrenoceptor blockade. Br J Pharmacol (1975) 0.75
Adenosine 3',5'-phosphate in biological materials. I. Purification and properties of cyclic 3',5'-nucleotide phosphodiesterase and use of this enzyme to characterize adenosine 3',5'-phosphate in human urine. J Biol Chem (1962) 12.79
A further Contribution regarding the influence of the different Constituents of the Blood on the Contraction of the Heart. J Physiol (1883) 8.09
The staircase phenomenon and the action of calcium on the heart. J Physiol (1956) 4.50
Inhibition of rabbit intestine mediated by alpha- and beta-adrenoceptors. Br J Pharmacol (1970) 2.64
The potentiation of cardiac inotropic responses to norepinephrine by theophylline. J Pharmacol Exp Ther (1963) 1.81
EFFECTS OF CAFFEINE ON MAMMALIAN ATRIAL MUSCLE, AND ITS INTERACTION WITH ADENOSINE AND CALCIUM. J Pharmacol Exp Ther (1965) 1.79
Effect of caffeine on cardiac contractile activity and radiocalcium movement. Am J Physiol (1963) 1.17
Calcium exchange in cardiac muscle: a basic mechanism of drug action. Am Heart J (1967) 1.00
The potentiation of rat uterine inhibitory responses to noradrenaline by theophylline and nitroglycerine. Br J Pharmacol (1968) 0.97
The action of imidazole on the effects of methyl-xanthines and catecholamines on cardiac contraction and phosphorylase activity. J Pharmacol Exp Ther (1967) 0.95
Mechanism of potentiation of contractor responses to catecholamines by methylxanthines in aortic strips. Br J Pharmacol (1971) 0.93
The mechanism of potentiation of inotropic responses to phenylephrine by theophylline. Br J Pharmacol (1969) 0.81
The mechanism of contractile effects of ouabain and zinc on the rat uterus. J Pharmacol Exp Ther (1970) 0.81
Prazosin, a selective antagonist of post-synaptic alpha-adrenoceptors [proceedings]. Br J Pharmacol (1977) 3.51
The pharmacology of antihypertensive drugs with special reference to vasodilators, alpha-adrenergic blocking agents and prazosin. Med J Aust (1977) 1.86
A comparsion of the effects of prazosin and hydrallazine on blood pressure, heart rate and plasma renin activity in conscious renal hypertensive dogs. Eur J Pharmacol (1975) 1.68
alpha-Adrenoceptors in the mouse vas deferens and their effects on its response to electrical stimulation. Br J Pharmacol (1978) 1.61
Presynaptic alpha-adrenoceptors and [3H]-noradrenaline overflow from the mouse was deferens [proceedings]. Br J Pharmacol (1978) 1.21
An inhibitory role for noradrenaline in the mouse vas deferens. Br J Pharmacol (1977) 1.18
A study of compounds which inhibit vascular smooth muscle contraction. Eur J Pharmacol (1973) 1.14
The relationship between pre-synaptic alpha-adrenoceptors, stimulation frequency and calcium [proceedings]. Br J Pharmacol (1977) 1.13
The significance of adenosine cyclic 3',5'-monophosphate for the contraction of smooth muscle. J Physiol (1967) 1.11
Presence of postsynaptic alpha 2-adrenoreceptors of predominantly extrasynaptic location in the vascular smooth muscle of the dog hind limb. Clin Sci (Lond) (1980) 1.05
Proceedings: Is morphine inhibition to the twitch response of the mouse vas deferens mediated via noradrenaline? Br J Pharmacol (1975) 1.05
The cardiovascular effects of L-dopa in the pithed rat. Br J Pharmacol (1974) 1.03
H1 antagonists: receptor affinity versus selectivity. Inflamm Res (2003) 1.02
New substituted 1,4-benzoxazine derivatives with potential intracellular calcium activity. J Med Chem (1998) 0.96
Peripheral dopamine receptors, potential targets for a new class of antihypertensive agents. Part I: Subclassification and functional description. Life Sci (1982) 0.95
The effects of release and depletion of endogenous noradrenaline on the transmission of impulses in the mouse vas deferens. Br J Pharmacol (1978) 0.92
Peripheral and central H1 histamine receptor occupancy by levocetirizine, a non-sedating antihistamine; a time course study in the guinea pig. Br J Pharmacol (2007) 0.91
The effect of depletion of the noradrenaline content on the response of the mouse vas deferens to electrical stimulation and to tyramine [proceedings]. J Physiol (1977) 0.91
Blockade of pre-synaptic alpha-adrenoceptors by metiamide [proceedings]. Br J Pharmacol (1978) 0.88
Recent developments in noradrenergic neurotransmission and its relevance to the mechanism of action of certain antihypertensive agents. Hypertension (1980) 0.88
Peripheral receptor populations involved in the regulation of gastrointestinal motility and the pharmacological actions of metoclopramide-like drugs. Life Sci (1985) 0.87
Proceedings: Is noradrenaline the motor transmitter in the mouse vas deferens? J Physiol (1976) 0.87
Differential blocking effects of several dopamine receptor antagonists for peripheral pre- and postsynaptic dopamine receptors in the anesthetized dog. J Pharmacol Exp Ther (1982) 0.86
Pharmacologic and therapeutic significance of alpha-adrenoceptor subtypes. J Cardiovasc Pharmacol (1985) 0.85
Comparison of in vivo acute lethal potency and in vitro cytotoxicity of 48 chemicals. Cell Biol Toxicol (1992) 0.84
Lack of correlation between presynaptic inhibition of noradrenaline release and end organ responses during nerve stimulation. Br J Pharmacol (1980) 0.83
Pre-synaptic alpha-adrenoceptor regulation of the twitch response of the mouse vas deferens [proceedings]. Br J Pharmacol (1977) 0.83
In vivo selectivity of prazosin but not of WB4101 for postsynaptic alpha-1 adrenoceptors. J Pharmacol Exp Ther (1981) 0.83
Aortic reactivity and electrophysiology in normotensive rats, spontaneously hypertensive rats and rats made hypertensive with desoxycorticosterone plus salt. Br J Pharmacol (1971) 0.82
The depression of sensitivity to noradrenaline caused by L-dopa. J Physiol (1973) 0.81
The mechanism of contractile effects of ouabain and zinc on the rat uterus. J Pharmacol Exp Ther (1970) 0.81
The mechanism of potentiation of inotropic responses to phenylephrine by theophylline. Br J Pharmacol (1969) 0.81
Pre- and postsynaptic alpha adrenoceptor selectivity studies with yohimbine and its two diastereoisomers rauwolscine and corynanthine in the anesthetized dog. J Pharmacol Exp Ther (1981) 0.81
Calcium ions, morphine tolerance and noradrenergic transmission in the mouse vas deferens. Eur J Pharmacol (1981) 0.81
Functional, behavioral, and histological changes induced by transient global cerebral ischemia in rats: effects of cinnarizine and flunarizine. J Cereb Blood Flow Metab (1989) 0.81
Effect of diltiazem upon contractile responses to phenylephrine, cirazoline, Sgd 101/75, St 587 and B-HT 920 in rabbit aorta and dog saphenous vein preparations. Eur J Pharmacol (1986) 0.81
Studies on the activity of bepridil as a scavenger of free radicals. Biochem Pharmacol (1990) 0.80
Dopamine inhibition of the twitch response of the mouse isolated vas deferens [proceedings]. Br J Pharmacol (1979) 0.79
Peripheral dopamine receptors, potential targets for a new class of antihypertensive agents. Part II: Sites and mechanisms of action of dopamine receptor agonists. Life Sci (1982) 0.79
Calcium entry blocking drugs, 'calcium antagonists' and vascular smooth muscle function. J Auton Pharmacol (1983) 0.79
A comparison of the stimulatory effects of metoclopramide and cinitapride in the guinea-pig isolated ileum. J Auton Pharmacol (1985) 0.79
Desensitization of the rat aortic strip to vasopressin by infusions of noradrenaline [proceedings]. Br J Pharmacol (1976) 0.78
Electrophysiological effects of Org 7797 in the closed-chest anaesthetized dog. Br J Pharmacol (1993) 0.78
Desensitization by noradrenaline of responses to stimulation of pre- and postsynaptic adrenoceptors. Br J Pharmacol (1982) 0.78
In vitro studies on 6-fluoronoradrenaline at several peripheral sympathetic neuroeffector junctions. Naunyn Schmiedebergs Arch Pharmacol (1981) 0.77
The ionic composition of aortic smooth muscle from A.S.-hypertensive rats. Br J Pharmacol (1973) 0.77
Electrophysiological effects of bepridil and its quaternary derivative CERM 11888 in closed chest anaesthetized dogs: a comparison with verapamil and diltiazem. Br J Pharmacol (1989) 0.77
The influence of pre-synaptic alpha-adrenoceptors on the overflow of noradrenaline in the stimulated mouse vas deferens [proceedings]. Br J Pharmacol (1977) 0.77
Major role for the carboxylic function of cetirizine and levocetirizine in their binding characteristics to human H1-histamine-receptors. Inflamm Res (2002) 0.76
Effects of the 5-hydroxytryptamine1A receptor agonists, 8-OH-DPAT, buspirone and flesinoxan, upon brain damage induced by transient global cerebral ischaemia in gerbils. Arch Int Pharmacodyn Ther (1996) 0.76
Ergometrine: a pre-synaptic alpha-adrenoceptro agonist [proceedings]. Br J Pharmacol (1977) 0.75
The effect of sympathetic nerve stimulation on [3H]-prazosin release in rabbit pulmonary arteries [proceedings]. Br J Pharmacol (1978) 0.75
Involvement of enteric neurones in the response of guinea-pig ileum preparations to metoclopramide. Br J Pharmacol (1986) 0.75
A comparison of 3 methods used for measuring the overflow of noradrenaline in the mouse isolated stimulated vas deferens [proceedings]. Br J Pharmacol (1978) 0.75
Pre-synaptic alpha-adrenoceptors and the inhibition by uptake blocking agents of the twitch response of the mouse vas deferens [proceedings]. Br J Pharmacol (1977) 0.75
Experimental renal hypertension and [3H]-noradrenaline release from the rabbit hypothalamus: enhanced K+-evoked overflow of tritium and lack of facilitation through presynaptic angiotensin II receptors [proceedings]. Br J Pharmacol (1980) 0.75
The effect of a high dose of prazosin, and transmural stimulation, on the disposition of transmitter noradrenaline in the rabbit pulmonary artery and the dog saphenous vein [proceedings]. Br J Pharmacol (1979) 0.75
The effect of exogenous noradrenaline on the overflow of [3H]-noradrenaline from the mouse vas deferens [proceedings]. Br J Pharmacol (1978) 0.75
Opiate tolerance and cross-tolerance in the mouse vas deferens [proceedings]. Br J Pharmacol (1979) 0.75
An action of ouabain to promote smooth muscle contraction unrelated to membrane ATPase inhibition. Br J Pharmacol (1968) 0.75
Comparative effects of bepridil, its quaternary derivative CERM 11888 and verapamil on caffeine-induced contracture in ferret hearts. Br J Pharmacol (1989) 0.75
The influence of drugs on the overflow of noradrenaline and the identification of receptors in guinea-pig atria. Br J Pharmacol (1982) 0.75
Phenoxybenzamine-induced inhibition of cirazoline pressor responses in pithed rats pretreated with organic or inorganic calcium entry blocking drugs. Eur J Pharmacol (1984) 0.75
A new series of M3 muscarinic antagonists based on the 4-amino-piperidine scaffold. Bioorg Med Chem Lett (2002) 0.75
Acetylcholine-induced relaxation of the rabbit aorta is preload-independent but markedly dependent upon the degree of excitatory agonist-induced tone. J Auton Pharmacol (1992) 0.75
The histamine H(1)-receptor antagonist cetirizine does not interact with bradykinin B(1) or B(2)-receptors in vitro. Inflamm Res (2004) 0.75
Design and synthesis of substituted compounds containing the 1, 4-benzodioxin subunit. New potential calcium antagonists. Eur J Med Chem (2000) 0.75
An in vitro investigation of the relationships between potency, lipophilicity, cytotoxicity and chemical class of representative calcium antagonist drugs. Pharmacol Res (1993) 0.75
Binding characteristics of [3H]levocetirizine to cloned human H1-histamine-receptors expressed in CHO cells. Inflamm Res (2002) 0.75
Paracetamol potentiates isaxonine toxicity in vitro. Toxicol Lett (1994) 0.75
Effect of the alpha-adrenoreceptor agonist LD 3098 (cirazoline) on the magnitude of end-organ responses induced by nerve stimulation and exogenous noradrenaline in a variety of sympathetically innervated animal tissues. Clin Sci (Lond) (1979) 0.75
Preferential noradrenergic innervation of alpha-adrenergic receptors in vascular smooth muscle. Hypertension (1981) 0.75
UK-14,275, a novel orally-active cardiac stimulant [proceedings]. Br J Pharmacol (1977) 0.75
The use of non-loaded, conscious dogs for the assessment of diuretic activity. Eur J Pharmacol (1974) 0.75
Protective effect of bepridil against veratrine-induced contracture in rat atria. Eur J Pharmacol (1992) 0.75
The role of presynaptic receptors in the cardiovascular actions of N,N-di-n-propyldopamine in the cat and dog. Naunyn Schmiedebergs Arch Pharmacol (1980) 0.75
Calcium antagonists can be classified using in vitro toxicity and potency indices. J Appl Toxicol (1992) 0.75
Caffeine-induced contractions in rabbit isolated renal artery are differentially inhibited by calcium antagonists. Eur J Pharmacol (1991) 0.75
Synergistic interactions between piracetam and dihydroergocristine in some animal models of cerebral hypoxia and ischaemia. Arzneimittelforschung (1986) 0.75
Contractile properties of various histaprodifen derivatives in guinea pig isolated ileum and trachea. Pharmacology (2006) 0.75
Potentiation of the gastric antisecretory activity of histamine H2-receptor antagonists by clebopride. Methods Find Exp Clin Pharmacol (1988) 0.75
Comparison of amitriptyline metabolism in hepatocytes from streptozocin-induced diabetic rats and from non-diabetic rats. Cell Biol Toxicol (1997) 0.75
Histamine H1-agonist properties of histaprodifen derivatives on guinea-pig isolated trachea and ileum. Inflamm Res (2003) 0.75
A comparison of the effects of verapamil and cinnarizine upon responses elicited by selective alpha 1- and alpha 2-adrenoceptor agonists in the autoperfused canine hindlimb. Eur J Pharmacol (1983) 0.75
In vitro calcium antagonistic and antioxidant effects of Org 13061 and its enantiomers, new potential antiatherosclerotic compounds. Fundam Clin Pharmacol (1997) 0.75
Failure of calcium channel blockade to reduce platelet-mediated cyclic flow variations in dogs with coronary stenosis and endothelial injury. J Cardiovasc Pharmacol (1995) 0.75
Lack of efficacy of 5-HT2A receptor antagonists to reduce brain damage after 3 minutes of transient global cerebral ischaemia in gerbils. Fundam Clin Pharmacol (1995) 0.75