Published in Nature on March 23, 1973
A saturable high affinity binding site for transcobalamin II-vitamin B12 complexes in human placental membrane preparations. J Clin Invest (1977) 1.00
Vitamin B 12 status in pregnancy among immigrants to Britain. Br Med J (1973) 0.91
Nitrate biosynthesis in man. Proc Natl Acad Sci U S A (1981) 3.14
Suction applied to a muscle biopsy maximizes sample size. Med Sci Sports Exerc (1982) 2.50
Measurement of leucine metabolism in man from a primed, continuous infusion of L-[1-3C]leucine. Am J Physiol (1980) 2.01
Ntau-methylhistidine (3-methylhistidine) and muscle protein turnover: an overview. Fed Proc (1978) 1.96
Role of nutrition in immunologic function. Physiol Rev (1980) 1.94
Insulin-mediated reduction of whole body protein breakdown. Dose-response effects on leucine metabolism in postabsorptive men. J Clin Invest (1985) 1.85
Mammalian nitrate biosynthesis: incorporation of 15NH3 into nitrate is enhanced by endotoxin treatment. Proc Natl Acad Sci U S A (1983) 1.83
Effect of glucocorticoid administration on the rate of muscle protein breakdown in vivo in rats, as measured by urinary excretion of N tau-methylhistidine. Biochem J (1979) 1.82
Dose-response characteristics of aflatoxin B1 carcinogenesis in the rat. Cancer Res (1967) 1.82
Validation of the tracer-balance concept with reference to leucine: 24-h intravenous tracer studies with L-[1-13C]leucine and [15N-15N]urea. Am J Clin Nutr (1994) 1.78
Nitrite and nitrate are formed by endogenous synthesis in the human intestine. Science (1978) 1.74
Acute and chronic effects of aflatoxin on the liver of domestic and laboratory animals: a review. Cancer Res (1969) 1.71
Relationship of plasma leucine and alpha-ketoisocaproate during a L-[1-13C]leucine infusion in man: a method for measuring human intracellular leucine tracer enrichment. Metabolism (1982) 1.65
The metabolic basis of the increase of the increase in energy expenditure in severely burned patients. JPEN J Parenter Enteral Nutr (1999) 1.56
Plasma arginine and citrulline kinetics in adults given adequate and arginine-free diets. Proc Natl Acad Sci U S A (1993) 1.54
Metabolism of 3-methylhistidine in man. Metabolism (1975) 1.51
Metabolic fate of an oral dose of 15N-labeled nitrate in humans: effect of diet supplementation with ascorbic acid. Cancer Res (1983) 1.48
Whole body nitric oxide synthesis in healthy men determined from [15N] arginine-to-[15N]citrulline labeling. Proc Natl Acad Sci U S A (1996) 1.48
Metabolism of administered 3-methylhistidine. Lack of muscle transfer ribonucleic acid charging and quantitative excretion as 3-methylhistidine and its N-acetyl derivative. J Biol Chem (1972) 1.47
Increased energy requirements and changes in body composition with resistance training in older adults. Am J Clin Nutr (1994) 1.46
Methionine and cysteine kinetics at different intakes of methionine and cysteine in elderly men and women. Am J Clin Nutr (1998) 1.45
Maximal parenteral glucose oxidation in hypermetabolic young children: a stable isotope study. JPEN J Parenter Enteral Nutr (1998) 1.45
L-arginine transport in the human coronary and peripheral circulation. Circulation (2004) 1.44
Starvation in the rat. II. Effect of age and obesity on protein sparing and fuel metabolism. Am J Physiol (1980) 1.43
Ntau-methylhistidine content of mixed proteins in various rat tissues. Biochim Biophys Acta (1975) 1.42
Zinc: health effects and research priorities for the 1990s. Environ Health Perspect (1994) 1.42
Whole-body leucine and lysine metabolism: response to dietary protein intake in young men. Am J Physiol (1981) 1.41
Overnutrition on resistance of dogs to distemper virus. Fed Proc (1967) 1.39
Report of the working group on protein and amino acid requirements. Eur J Clin Nutr (1996) 1.38
Effect of infection on skeletal muscle ribosomes in rats fed adequate or low protein. J Nutr (1968) 1.36
Myofibrillar protein turnover and urinary N-tau-methylhistidine output. Response to dietary supply of protein and energy. Biochem J (1975) 1.35
Synthesis and degradation of mixed proteins, and composition changes in skeletal muscle of malnourished and refed rats. J Nutr (1971) 1.33
Sequential morphologic changes in aflatoxin B carcinogenesis in the rat. Cancer Res (1968) 1.33
Incorporation of urea and ammonia nitrogen into ileal and fecal microbial proteins and plasma free amino acids in normal men and ileostomates. Am J Clin Nutr (1999) 1.33
Effects of resistance training and dietary protein intake on protein metabolism in older adults. Am J Physiol (1995) 1.32
The role of diet and the reticuloendothelial system in the response of rats to Salmonella typhilmurium infection. Br J Exp Pathol (1968) 1.32
Increased protein requirements in elderly people: new data and retrospective reassessments. Am J Clin Nutr (1994) 1.30
Blood glutathione synthesis rates in healthy adults receiving a sulfur amino acid-free diet. Proc Natl Acad Sci U S A (2000) 1.27
Depressed cell-mediated immunity in megaloblastic anemia due to folic acid deficiency. Am J Clin Nutr (1975) 1.23
Potential use of 3-methylhistidine excretion as an index of progressive reduction in muscle protein catabolism during starvation. Metabolism (1973) 1.22
Splanchnic metabolism of dietary arginine in relation to nitric oxide synthesis in normal adult man. Proc Natl Acad Sci U S A (1993) 1.21
Quantitative study in vivo of methionine cycle in humans using [methyl-2H3]- and [1-13C]methionine. Am J Physiol (1988) 1.21
Dietary enhancement of intestinal carcinogenesis by dimethylhydrazine in rats. Nature (1974) 1.17
Induction by dimethylhydrazine of intestinal carcinoma in normal rats and rats fed high or low levels of vitamin A. Cancer Res (1973) 1.16
Recovery of 13C in breath from NaH13CO3 infused by gut and vein: effect of feeding. Am J Physiol (1989) 1.15
Total human body protein synthesis in relation to protein requirements at various ages. Nature (1975) 1.13
Selenium: a case for its essentiality in man. N Engl J Med (1981) 1.11
Control of food intake in older men. JAMA (1994) 1.10
Dietary arginine uptake by the splanchnic region in adult humans. Am J Physiol (1993) 1.09
Structure-activity relationships in toxicity and carcinogenicity of aflatoxins and analogs. Cancer Res (1971) 1.09
Increased rates of whole body protein synthesis and breakdown in children recovering from burns. Ann Surg (1978) 1.08
Tumorigenicity of fluoranthene in a newborn mouse lung adenoma bioassay. Carcinogenesis (1984) 1.08
Sensitivity of myofibrillar proteins to glucocorticoid-induced muscle proteolysis. Am J Physiol (1987) 1.08
Glucose and insulin effects on the novo amino acid synthesis in young men: studies with stable isotope labeled alanine, glycine, leucine, and lysine. Metabolism (1982) 1.07
Mycotoxins: toxicity, carcinogenicity, and the influence of various nutritional conditions. Environ Health Perspect (1974) 1.07
Whole body de novo amino acid synthesis in type I (insulin-dependent) diabetes studied with stable isotope-labeled leucine, alanine, and glycine. Diabetes (1985) 1.07
Leukocyte endogenous mediator alters protein dynamics in rats. Metabolism (1983) 1.07
Determination of the isotope enrichment of one or a mixture of two stable labelled tracers of the same compound using the complete isotopomer distribution of an ion fragment; theory and application to in vivo human tracer studies. Biol Mass Spectrom (1993) 1.06
The plasma flux and oxidation rate of ornithine adaptively decline with restricted arginine intake. Proc Natl Acad Sci U S A (1994) 1.06
Functional characteristics of lymphocytes isolated from the rat large intestine. Response to T-cell mitogens and natural killer cell activity. Gastroenterology (1984) 1.05
High-carbohydrate, high-fiber diets increase peripheral insulin sensitivity in healthy young and old adults. Am J Clin Nutr (1990) 1.04
Zinc deficiency and methylbenzylnitrosamine-induced esophageal cancer in rats. J Natl Cancer Inst (1978) 1.04
Plasma methionine and cysteine kinetics in response to an intravenous glutathione infusion in adult humans. Am J Physiol (1996) 1.04
Energy metabolism and requirements in the cancer patient. Cancer Res (1977) 1.03
Cysteine kinetics and oxidation at different intakes of methionine and cystine in young adults. Am J Clin Nutr (2000) 1.02
Plasma arginine kinetics in adult man: response to an arginine-free diet. Metabolism (1994) 1.02
Carcinogenic effects of low dietary levels of aflatoxin B1 in rats. Food Cosmet Toxicol (1974) 1.02
Labile methyl groups and the promotion of cancer. Annu Rev Nutr (1986) 1.01
Wheat proteins in relation to protein requirements and availability of amino acids. Am J Clin Nutr (1985) 1.01
Vitamins and cancer prevention: issues and dilemmas. Cancer (1981) 1.01
Plasma tryptophan response curve and its relation to tryptophan requirements in young adult men. J Nutr (1971) 1.01
Urea cycle intermediate kinetics and nitrate excretion at normal and "therapeutic" intakes of arginine in humans. Am J Physiol (1995) 1.01
The 24-h kinetics of leucine oxidation in healthy adults receiving a generous leucine intake via three discrete meals. Am J Clin Nutr (1995) 1.01
Cysteine metabolism and whole blood glutathione synthesis in septic pediatric patients. Crit Care Med (2001) 1.01
Alanine kinetics in humans: influence of different isotopic tracers. Am J Physiol (1984) 1.00
Influence of age on energy requirements. Am J Clin Nutr (1995) 1.00
Arginine and ornithine kinetics in severely burned patients: increased rate of arginine disposal. Am J Physiol Endocrinol Metab (2001) 1.00
Carcinogenicity in rats of the nitrosated bile acid conjugates N-nitrosoglycocholic acid and N-nitrosotaurocholic acid. Cancer Res (1985) 1.00
Metabolic effects of very low calorie weight reduction diets. J Clin Invest (1984) 1.00
Plasma arginine, citrulline, and ornithine kinetics in adults, with observations on nitric oxide synthesis. Am J Physiol (1995) 1.00
Synthesis and degradation rates of collagens in vivo in whole skin of rats, studied with 1802 labelling. Biochem J (1986) 0.99
Quantitative aspects of glucose production and metabolism in healthy elderly subjects. Diabetes (1982) 0.99
Nitrite promotes lymphoma incidence in rats. Science (1979) 0.99
Isolation and quantitation of Ntau-methylhistidine in actin and myosin of rat skeletal muscle: use of pyridine elution of protein hydrolysates on ion-exchange resins. Biochim Biophys Acta (1974) 0.99
Whole body protein turnover in aging man. Exp Gerontol (1976) 0.99
Methionine kinetics in adult men: effects of dietary betaine on L-[2H3-methyl-1-13C]methionine. Am J Clin Nutr (1991) 0.98
Effect of isometric exercises on body potassium and dietary protein requirements of young men. Am J Clin Nutr (1977) 0.98
Morphology and distribution of 1,2-dimethylhydrazine dihydrochloride-induced colon tumors and their relationship to gut-associated lymphoid tissue in the rat. J Natl Cancer Inst (1984) 0.98
Role of interleukin 1 and tumor necrosis factor on energy metabolism in rabbits. Am J Physiol (1988) 0.98
Similar 24-h pattern and rate of carbon dioxide production, by indirect calorimetry vs. stable isotope dilution, in healthy adults under standardized metabolic conditions. J Nutr (1994) 0.98
The influence of intravenous nutrition on protein dynamics following surgery. Metabolism (1981) 0.97
Palmitate and glycerol kinetics during brief starvation in normal weight young adult and elderly subjects. J Clin Invest (1986) 0.97
Underfeeding and body weight regulation in normal-weight young men. Am J Physiol (1992) 0.97
Insulin dose-dependent reductions in plasma amino acids in man. Am J Physiol (1986) 0.97
Energy costs of fat and protein deposition in the human infant. Am J Clin Nutr (1988) 0.97
[1-13C; methyl-2H3]methionine kinetics in humans: methionine conservation and cystine sparing. Am J Physiol (1990) 0.97