Published in Science on November 08, 1968
An analysis of the sequences of the variable regions of Bence Jones proteins and myeloma light chains and their implications for antibody complementarity. J Exp Med (1970) 9.83
The anamnestic antibody response to type 3 specific pneumococcal polysaccharide. J Exp Med (1969) 0.96
Electrophoretically homogeneous anti-DNP antibodies with restricted isoelectric points elicited in mice by immunization with the antigen papain-S-DNPL. Proc Natl Acad Sci U S A (1970) 0.96
Degeneracy of the immune response to sheep red cells. Immunology (1972) 0.95
Specific Lesions of Peripheral Blood Vessels in Rheumatism. Am J Pathol (1926) 26.13
Factors Necessary for Massive Growth of Group A Hemolytic Streptococcus. J Bacteriol (1942) 14.27
The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium. J Embryol Exp Morphol (1985) 12.74
An Improved Medium for the Cultivation of Hemolytic Streptococcus. J Bacteriol (1942) 12.34
Enlargement of the Parathyroid Glands in Renal Disease. Am J Pathol (1935) 9.18
Diphtheria toxin. Annu Rev Biochem (1977) 8.44
Binding of immunogenic peptides to Ia histocompatibility molecules. Nature (1985) 8.39
Application of a radioimmunoassay for angiotensin I to the physiologic measurements of plasma renin activity in normal human subjects. J Clin Endocrinol Metab (1969) 7.56
Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1. Mol Cell (1999) 6.79
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HIV prevalence, risk behaviors, health care use, and mental health status of transgender persons: implications for public health intervention. Am J Public Health (2001) 6.16
Determination of therapeutic and toxic serum digoxin concentrations by radioimmunoassay. N Engl J Med (1969) 6.15
Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli. Proc Natl Acad Sci U S A (1988) 6.14
Seroprevalence of HIV and risk behaviors among young homosexual and bisexual men. The San Francisco/Berkeley Young Men's Survey. JAMA (1994) 5.83
The pathology of nutritional muscular dystrophy in young rats. Am J Pathol (1939) 5.78
The application of 0.1 M quadrol to the microsequence of proteins and the sequence of tryptic peptides. Biochemistry (1975) 5.31
Mutation in the structural gene for diphtheria toxin carried by temperate phage . Nat New Biol (1971) 4.67
Intranuclear Inclusions in Visceral Disease. Am J Pathol (1925) 4.31
Adaptations of the organism to changes in oxygen pressure. J Physiol (1931) 4.23
Dynamics and segregation of cell-matrix adhesions in cultured fibroblasts. Nat Cell Biol (2000) 3.99
Screening for dementia with the memory impairment screen. Neurology (1999) 3.92
Certain Cytoplasmic Inclusions of Liver Cells. Am J Pathol (1936) 3.87
Diphtheria toxin and related proteins. I. Isolation and properties of mutant proteins serologically related to diphtheria toxin. J Biol Chem (1973) 3.78
Muscular dystrophy in mice on vitamin E-deficient diet. Am J Pathol (1942) 3.77
An immunological study of the diphtheria toxin molecule. Immunochemistry (1972) 3.48
"Ceroid" Pigment in Human Tissues. Am J Pathol (1946) 3.45
Structure-activity relationships in diphtheria toxin. J Biol Chem (1971) 3.28
Digitalis intoxication. A prospective clinical study with serum level correlations. N Engl J Med (1971) 3.27
A cell wall polysaccharide-hydrolyzing enzyme system in Avena sativa L. coleoptiles. Biochim Biophys Acta (1967) 3.06
Dopamine D4 receptor (D4DR) exon III polymorphism associated with the human personality trait of Novelty Seeking. Nat Genet (1996) 2.92
Neurologic abnormalities in murderers. Neurology (1995) 2.90
Studies on migration inhibitory factor (MIF): recovery of MIF activity after purification by gel filtration and disc electrophoresis. Cell Immunol (1970) 2.86
Diphtheria. Science (1973) 2.83
Inclusions in Renal Epithelial Cells Following the Use of Certain Bismuth Compounds. Am J Pathol (1934) 2.70
Digoxin intoxication: the relationship of clinical presentation to serum digoxin concentration. J Clin Invest (1970) 2.66
Synthesis of diphtheria tox-gene products in Escherichia coli extracts. Proc Natl Acad Sci U S A (1974) 2.62
Leisure activities and the risk of amnestic mild cognitive impairment in the elderly. Neurology (2006) 2.51
THE HISTOPATHOLOGY OF NUTRITIONAL ENCEPHALOMALACIA OF CHICKS. J Exp Med (1931) 2.49
Reversal of advanced digoxin intoxication with Fab fragments of digoxin-specific antibodies. N Engl J Med (1976) 2.49
NUTRITIONAL MUSCULAR DYSTROPHY IN THE GUINEA PIG AND RABBIT. J Exp Med (1931) 2.48
Studies on the molecular epidemiology of diphtheria. Lancet (1983) 2.45
Characterization of antibodies of high affinity and specificity for the digitalis glycoside digoxin. Biochemistry (1970) 2.39
Anatomy, histologic features, and vascularity of the adult acetabular labrum. Clin Orthop Relat Res (2001) 2.38
Tei-index in patients with mild-to-moderate congestive heart failure. Eur Heart J (2000) 2.37
EXPERIMENTAL RICKETS IN RATS : I. A DIET PRODUCING RICKETS IN WHITE RATS, AND ITS PREVENTION BY THE ADDITION OF AN INORGANIC SALT. J Exp Med (1921) 2.33
Objective documentation of child abuse and dissociation in 12 murderers with dissociative identity disorder. Am J Psychiatry (1997) 2.31
Binding of triton X-100 to diphtheria toxin, crossreacting material 45, and their fragments. Proc Natl Acad Sci U S A (1976) 2.27
Antigenic competition at the level of peptide-Ia binding. Proc Natl Acad Sci U S A (1986) 2.23
Differences in the temporal trends of HIV seroincidence and seroprevalence among sexually transmitted disease clinic patients, 1989-1998: application of the serologic testing algorithm for recent HIV seroconversion. Am J Epidemiol (2001) 2.22
Presence of 2 different viral agents in brain cells of patients with subacute sclerosing panencephalitis. Proc Soc Exp Biol Med (1970) 2.20
Memory and mental status correlates of modified Braak staging. Neurobiol Aging (2000) 2.15
Brief report: recognition of acute myocarditis masquerading as acute myocardial infarction. N Engl J Med (1993) 2.14
Antigenic determinants in proteins coincide with surface regions accessible to large probes (antibody domains). Proc Natl Acad Sci U S A (1986) 2.13
Heart failure in outpatients: a randomized trial of digoxin versus placebo. N Engl J Med (1982) 2.09
A Case of Rheumatic Aortitis with Early Lesions in the Media. Am J Pathol (1926) 2.05
EXPERIMENTAL PNEUMONIA IN GUINEA PIGS : I. THE EFFECT OF CERTAIN TOXIC AUTOLYSATES OF PNEUMOCOCCI. J Exp Med (1928) 2.03
Anti-DNA antibodies form immune deposits at distinct glomerular and vascular sites. Kidney Int (1992) 2.01
Metabolic turnover in cell wall constituents of Avena sativa L. coleoptile sections. Biochim Biophys Acta (1967) 1.97
FACTORS INVOLVED IN PRODUCTION OF CLOSTRIDIUM WELCHII ALPHA TOXIN. J Exp Med (1947) 1.94
Fetal surgery for congenital hydronephrosis. N Engl J Med (1982) 1.94
Classification of mouse VK groups based on the partial amino acid sequence to the first invariant tryptophan: impact of 14 new sequences from IgG myeloma proteins. Mol Immunol (1982) 1.93
Risky behaviors among Ohio Appalachian adults. Prev Chronic Dis (2006) 1.91
Minimal infective dose of attenuated poliovirus for man. Am J Public Health Nations Health (1967) 1.89
Monoclonal antibodies to a synthetic fibrin-like peptide bind to human fibrin but not fibrinogen. Science (1983) 1.89
Diphtheria toxin, protein synthesis, and the cell. Fed Proc (1973) 1.87
Diphtheria toxin and related proteins. II. Kinetic studies on intoxication of HeLa cells by diphtheria toxin and related proteins. J Biol Chem (1973) 1.87
The Testis in Vitamin E-Deficient Guinea-Pigs. Am J Pathol (1944) 1.87
Studies on the mode of action of diphtheria toxin. VII. Toxin-stimulated hydrolysis of nicotinamide adenine dinucleotide in mammalian cell extracts. J Exp Med (1969) 1.83
Reconstitution of diphtheria toxin from two nontoxic cross-reacting mutant proteins. Science (1972) 1.82
Thy-1, a novel marker for angiogenesis upregulated by inflammatory cytokines. Circ Res (1998) 1.81
Studies on the mode of action of diphtheria toxin. IV. Specificity of the cofactor (NAD) requirement for toxin action in cell-free systems. J Exp Med (1967) 1.80
A radioimmunoassay for bradykinin in plasma and synovial fluid. J Lab Clin Med (1969) 1.79
Defective ubiquitinylation of EGFR mutants of lung cancer confers prolonged signaling. Oncogene (2007) 1.79
Cloning and functional analysis of the promoter for KDR/flk-1, a receptor for vascular endothelial growth factor. J Biol Chem (1995) 1.78
Integrating public health information and surveillance systems. J Public Health Manag Pract (1996) 1.76
Interaction of diphtheria toxin with mammalian cell membranes. J Biol Chem (1976) 1.74
Action of diphtheria toxin in the guinea pig. J Exp Med (1970) 1.71
Diphtheria toxin and related proteins: effect of route of injection on toxicity and the determination of cytotoxicity for various cultured cells. J Infect Dis (1982) 1.67
Specificity of the T cell receptor: two different determinants are generated by the same peptide and the I-Ak molecule. J Immunol (1985) 1.67
Promotion of vascular smooth muscle cell growth by homocysteine: a link to atherosclerosis. Proc Natl Acad Sci U S A (1994) 1.66
Digitalis (third of four parts). N Engl J Med (1973) 1.63
Subacute sclerosing panencephalitis: structures resembling myxovirus nucleocapsids in cells cultured from brain. Nature (1969) 1.62
Bezoars in the stomach and small bowel--CT appearance. Clin Radiol (1999) 1.62
Studies on the mode of action of diphtheria toxin. 3. Site of toxin action in cell-free extracts. J Exp Med (1967) 1.61
Amino acid sequence analysis with methyl isothiocyanate. Resolution of the methylthiohydantoins by gas-liquid partition chromatography. Biochemistry (1970) 1.61
Comparison of subacute sclerosing panencephalitis and measles viruses: an electron microscope study. J Virol (1971) 1.61
Structure of antibody hypervariable loops reproduced by a conformational search algorithm. Nature (1988) 1.61
A risk profile of street youth in northern California: implications for gender-specific human immunodeficiency virus prevention. J Adolesc Health (1997) 1.59
"Emergency" granulopoiesis in G-CSF-deficient mice in response to Candida albicans infection. Blood (2000) 1.59
Diagnostic accuracy of antimyosin scintigraphy in suspected myocarditis. J Nucl Cardiol (1997) 1.58
HIV seroprevalence and risk behaviors among lesbians and bisexual women in San Francisco and Berkeley, California. Am J Public Health (1995) 1.57
Thresholdless nanoscale coaxial lasers. Nature (2012) 1.56
A new attenuated rubella virus grown in human fibroblasts: evidence for reduced nasopharyngeal excretion. Am J Epidemiol (1967) 1.56
Oral poliovirus vaccination in newborn African infants. The inhibitory effect of breast feeding. Am J Dis Child (1966) 1.56
Treatment of life-threatening digitalis intoxication with digoxin-specific Fab antibody fragments: experience in 26 cases. N Engl J Med (1982) 1.56
Diphtheria toxin and related proteins. 3. Reconstitution of hybrid "diphtheria toxin" from nontoxic mutant proteins. J Biol Chem (1973) 1.55
The Protracted Effect of a Single Dose of dl-Alpha-Tocopherol Acetate upon the Testes of Rats on Vitamin E-Deficient Diet. Am J Pathol (1944) 1.55
Antimyosin antibody cardiac imaging: its role in the diagnosis of myocarditis. J Am Coll Cardiol (1990) 1.55
A Study of the Involutional changes which occur in the Adrenal Cortex during Infancy. J Med Res (1916) 1.55
Structural features of gamma-immunoglobulin, antibody, and their fragments. Circular dichroism studies. Biochemistry (1968) 1.55