Isolation of ouabain-resistant human diploid fibroblasts.

Galactokinase mutants of Chinese hamster somatic cells resistant to 2-deoxygalactose. Genetics (1976) 1.59

Spontaneous fusion in vivo between normal host and tumor cells: possible contribution to tumor progression and metastasis studied with a lectin-resistant mutant tumor. Mol Cell Biol (1983) 1.32

Mutagenesis in S49 mouse lymphoma cells: induction of resistance to ouabain, 6-thioguanine, and dibutyryl cyclic AMP. Proc Natl Acad Sci U S A (1977) 1.12

Amplification of DNA sequences coding for the Na,K-ATPase alpha-subunit in ouabain-resistant C+ cells. Mol Cell Biol (1986) 1.11

Isolation and characterization of mutants of human diploid fibroblasts resistant to diphtheria toxin. Proc Natl Acad Sci U S A (1978) 1.08

Isolation and characterization of dexamethasone-resistant mutants from human lymphoid cell line CEM-C7. Mol Cell Biol (1981) 1.01

Cardiac glycosides induce cell death in human cells by inhibiting general protein synthesis. PLoS One (2009) 1.00

Induction of ouabain-resistant mutations in C3H 10T1/2 mouse cells by ultraviolet light. Proc Natl Acad Sci U S A (1978) 0.97

Genetic control of cobalamin binding in normal and mutant cells: assignment of the gene for 5-methyltetrahydrofolate:L-homocysteine S-methyltransferase to human chromosome 1. Proc Natl Acad Sci U S A (1979) 0.96

HeLa cell variants that differ in sensitivity to monofunctional alkylating agents, with independence of cytotoxic and mutagenic responses. Proc Natl Acad Sci U S A (1979) 0.94

Increased resistance of cystic fibrosis fibroblasts to ouabain toxicity. Proc Natl Acad Sci U S A (1977) 0.94

Potential roles of 3'-5' exonuclease activity of NM23-H1 in DNA repair and malignant progression. J Bioenerg Biomembr (2006) 0.90

Identification of a region within the Na,K-ATPase alpha subunit that contributes to differential ouabain sensitivity. Mol Cell Biol (1989) 0.87

Human bronchus-mediated mutagenesis of mammalian cells by carcinogenic polynuclear aromatic hydrocarbons. Proc Natl Acad Sci U S A (1978) 0.86

Functional expression of the genomic DNA sequences encoding mouse Na,K-ATPase alpha 1 gene by cotransfection of overlapping genomic DNA segments. Mol Cell Biol (1990) 0.85

Locus specificity in the mutability of L5178Y mouse lymphoma cells: the role of multilocus lesions. Proc Natl Acad Sci U S A (1986) 0.85

Chromosome-mediated transfer of the murine Na,K-ATPase alpha subunit confers ouabain resistance. Mol Cell Biol (1987) 0.85

Fragile X syndrome: search for phenotypic manifestations at loci for hypoxanthine phosphoribosyltransferase and glucose-6-phosphate dehydrogenase. Am J Hum Genet (1981) 0.82

Isolation of diploid human lymphoblast mutants presumably homozygous for ouabain resistance. Proc Natl Acad Sci U S A (1980) 0.76

A threshold of endogenous stress is required to engage cellular response to protect against mutagenesis. Sci Rep (2016) 0.76

Altered pattern of replication of human chromosomes in a human fibroblast-mouse cell hybrid. Proc Natl Acad Sci U S A (1978) 0.75

Identification of the cystic fibrosis gene: genetic analysis. Science (1989) 33.61

Cystic fibrosis locus defined by a genetically linked polymorphic DNA marker. Science (1985) 5.81

A polymorphic DNA marker linked to cystic fibrosis is located on chromosome 7. Nature (1985) 5.07

Linkage of cystic fibrosis to two tightly linked DNA markers: joint report from a collaborative study. Am J Hum Genet (1986) 3.83

Effects of nutrient deprivation on Vibrio cholerae. Appl Environ Microbiol (1983) 3.78

Cloning of cDNAs for Fanconi's anaemia by functional complementation. Nature (1992) 2.97

Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2. J Biol Chem (1998) 2.72

Introduction and recovery of a selectable bacterial gene from the genome of mammalian cells. Mol Cell Biol (1982) 2.59

Expression cloning of a cDNA for the major Fanconi anaemia gene, FAA. Nat Genet (1996) 2.36

Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia. Nat Genet (1996) 2.32

Fanconi anemia group C protein prevents apoptosis in hematopoietic cells through redox regulation of GSTP1. Nat Med (2001) 2.26

Loss of FancC function results in decreased hematopoietic stem cell repopulating ability. Blood (1999) 2.00

The Fanconi anaemia group G gene FANCG is identical with XRCC9. Nat Genet (1998) 1.99

Evidence for at least four Fanconi anaemia genes including FACC on chromosome 9. Nat Genet (1992) 1.98

Isolation of mutants of cultured mammalian cells. Methods Cell Biol (1973) 1.95

Multiple inhibitory cytokines induce deregulated progenitor growth and apoptosis in hematopoietic cells from Fac-/- mice. Blood (1998) 1.93

In vivo cell-specific expression of the cystic fibrosis transmembrane conductance regulator. Nature (1991) 1.90

Classification of Fanconi anemia patients by complementation analysis: evidence for a fifth genetic subtype. Blood (1995) 1.82

HSC clinical trials controversy continues. Hospital for Sick Children. Nat Med (1999) 1.78

Bone marrow failure in the Fanconi anemia group C mouse model after DNA damage. Blood (1998) 1.74

Analysis of gene expression in a complex differentiation hierarchy by global amplification of cDNA from single cells. Curr Biol (1995) 1.67

DNA marker haplotype association with pancreatic sufficiency in cystic fibrosis. Am J Hum Genet (1989) 1.66

The Fanconi anaemia gene FANCF encodes a novel protein with homology to ROM. Nat Genet (2000) 1.64

P-glycoprotein in human sarcoma: evidence for multidrug resistance. J Clin Oncol (1987) 1.64

Evidence for at least eight Fanconi anemia genes. Am J Hum Genet (1997) 1.61

A nonsense mutation and exon skipping in the Fanconi anaemia group C gene. Hum Mol Genet (1993) 1.51

Isolation of a cDNA representing the Fanconi anemia complementation group E gene. Am J Hum Genet (2000) 1.51

Persistence of freely replicating SV40 recombinant molecules carrying a selectable marker in permissive simian cells. Cell (1982) 1.47

Lung disease in mice with cystic fibrosis. J Clin Invest (1997) 1.44

Fanconi anemia and novel strategies for therapy. Blood (1994) 1.39

Induction of Fanconi anemia cellular phenotype in human 293 cells by overexpression of a mutant FAC allele. J Clin Invest (1996) 1.38

The morphogenesis of bacteriophage lambda. II. Identification of the principal structural proteins. Virology (1970) 1.36

Isolation of temperature-sensitive mutants of L-cells. Proc Natl Acad Sci U S A (1970) 1.34

Phosphatase inhibitors activate normal and defective CFTR chloride channels. Proc Natl Acad Sci U S A (1994) 1.34

Genetic analysis of cystic fibrosis using linked DNA markers. Am J Hum Genet (1986) 1.32

The Tlx-2 homeobox gene is a downstream target of BMP signalling and is required for mouse mesoderm development. Development (1998) 1.29

Linkage of cystic fibrosis to the pro alpha 2(I) collagen gene, COL1A2, on chromosome 7. Cytogenet Cell Genet (1986) 1.29

CFTR expression is regulated during both the cycle of the seminiferous epithelium and the oestrous cycle of rodents. Nat Genet (1993) 1.26

Selective and nonselective isolation of temperature-sensitive mutants of mouse L-cells and their characterization. J Cell Physiol (1971) 1.25

Susceptibility of Fanconi's anemia lymphoblasts to DNA-cross-linking and alkylating agents. Cancer Res (1982) 1.24

Cell-specific localization of CFTR mRNA shows developmentally regulated expression in human fetal tissues. Hum Mol Genet (1993) 1.21

Ouabain as a selective agent in the isolation of somatic cell hybrids. Cytogenet Cell Genet (1975) 1.20

Immunosuppressive and immunostimulatory factors produced by malignant cells in vitro. Int J Cancer (1974) 1.20

Fanconi anemia C gene product plays a role in the fidelity of blunt DNA end-joining. J Mol Biol (1998) 1.19

Resident preferences for the clinical teaching of ambulatory care. J Med Educ (1982) 1.19

Regulation of CFTR expression and function during differentiation of intestinal epithelial cells. EMBO J (1992) 1.18

Optical properties of astaxanthin solutions and aggregates. Biochemistry (1968) 1.16

Production of serum-blocking material by mutants of the left arm of the lambda chromosome. Virology (1969) 1.16

Phenotypic abnormalities in long-term surviving cystic fibrosis mice. Pediatr Res (1996) 1.16

Hematopoietic compartment of Fanconi anemia group C null mice contains fewer lineage-negative CD34+ primitive hematopoietic cells and shows reduced reconstruction ability. Exp Hematol (1999) 1.14

A simple, rapid method for isolation of high quality genomic DNA from animal tissues. Nucleic Acids Res (1995) 1.12

Complementation groups: one or more per gene? Nat Genet (1995) 1.10

Differential cellular expression of cystic fibrosis transmembrane regulator in human reproductive tissues. Clues for the infertility in patients with cystic fibrosis. Am J Pathol (1994) 1.10

Effect of cycloheximide and dexamethasone phosphate on hyaluronic acid synthesis and secretion in cultured human skin fibroblasts. J Cell Physiol (1981) 1.09

Identification of two complementation groups in Fanconi anemia. Somat Cell Mol Genet (1985) 1.06

Mapping of the cystic fibrosis locus on chromosome 7. Cold Spring Harb Symp Quant Biol (1986) 1.06

Defective hematopoiesis and hepatic steatosis in mice with combined deficiencies of the genes encoding Fancc and Cu/Zn superoxide dismutase. Blood (2001) 1.05

The multidrug resistance and cystic fibrosis genes have complementary patterns of epithelial expression. EMBO J (1992) 1.05

Biochemical and molecular genetics of cystic fibrosis. Adv Hum Genet (1991) 1.04

Cloning and analysis of the murine Fanconi anemia group C cDNA. Hum Mol Genet (1993) 1.04

The human homolog of insect-derived growth factor, CECR1, is a candidate gene for features of cat eye syndrome. Genomics (2000) 1.02

Suppression of apoptosis in hematopoietic factor-dependent progenitor cell lines by expression of the FAC gene. Blood (1996) 1.02

Stimulation of the cystic fibrosis transmembrane regulator expression by estrogen in vivo. Endocrinology (1993) 1.01

Development of an epithelium-specific expression cassette with human DNA regulatory elements for transgene expression in lung airways. Proc Natl Acad Sci U S A (1997) 1.01

Dominance of colchicine resistance in hybrid CHO cells. Somatic Cell Genet (1978) 1.01

Cloning of cDNAs for Fanconi's anaemia by functional complementation. Nature (1992) 1.01

Human diploid fibroblast mutants with altered RNA polymerase II. Somatic Cell Genet (1976) 1.00

Mapping of DNA markers linked to the cystic fibrosis locus on the long arm of chromosome 7. Am J Hum Genet (1987) 1.00

A Leu554-to-Pro substitution completely abolishes the functional complementing activity of the Fanconi anemia (FACC) protein. Hum Mol Genet (1993) 0.99

Mutagenesis at the ouabain-resistance locus in human diploid fibroblasts. Mutat Res (1977) 0.98

Association of the TLX-2 homeodomain and 14-3-3eta signaling proteins. J Biol Chem (1998) 0.98

Isolation of plasma membranes from human skin fibroblasts. J Membr Biol (1977) 0.97

CFTR expression and organ damage in cystic fibrosis. Ann Intern Med (1995) 0.97

A functionally active retrovirus vector for gene therapy in Fanconi anemia group C. Blood (1994) 0.97

Estrogen-dependent expression of the cystic fibrosis transmembrane regulator gene in a novel uterine epithelial cell line. J Cell Sci (1994) 0.97

Failure of the phorbol ester 12-O-tetradecanoylphorbol-13-acetate to enhance sister chromatid exchange, mitotic segregation, or expression of mutations in Chinese hamster cells. Cancer Res (1980) 0.96

Selection of mutant Chinese hamster ovary cells altered glycoproteins by means of tritiated fucose suicide. Mol Cell Biol (1981) 0.96

Water drinking induced in sheep by angiotensin--a physiological or pharmacological effect? J Comp Physiol Psychol (1975) 0.96

Drug sensitivity spectra in Fanconi anemia lymphoblastoid cell lines of defined complementation groups. Mutat Res (1999) 0.95

Characterisation of the exon structure of the Fanconi anaemia group C gene by vectorette PCR. Hum Mol Genet (1993) 0.94

HeLa cell variants that differ in sensitivity to monofunctional alkylating agents, with independence of cytotoxic and mutagenic responses. Proc Natl Acad Sci U S A (1979) 0.94

Specific cellular defects in patients with Fanconi anemia. J Cell Physiol (1979) 0.94

Enzyme-induced posterior vitreous detachment in the rat produces increased lens nuclear pO2 levels. Exp Eye Res (2008) 0.93

Functions of a family medicine preceptorship. J Med Educ (1979) 0.93

New immunohistochemical "sandwich" staining method for mdr1 P-glycoprotein detection with JSB-1 monoclonal antibody in formalin-fixed, paraffin-embedded human tissues. Am J Pathol (1994) 0.92

Evaluation of a self-help dietary intervention in a primary care setting. Am J Public Health (1992) 0.92

Linkage between the loci for cystic fibrosis and paraoxonase. Clin Genet (1986) 0.92

(Na, K)ATPase activity in membrane preparations of ouabain-resistant HeLa cells. Biochemistry (1977) 0.92

Abnormal levels of 3':5'-cyclic AMP in isoproterenol-stimulated fibroblasts from patients with cystic fibrosis. Proc Natl Acad Sci U S A (1976) 0.92

Dissociation-produced loss of regulatory control of homoserine dehydrogenase of Rhodospirillum rubrum. I. Factors which affect the interconversion of the regulatable and nonregulatable states. Biochemistry (1969) 0.91

Reduced synthesis of [14C]mannosyl oligosaccharide-lipid by membranes prepared from concanavalin A-resistant Chinese hamster ovary cells. J Biol Chem (1977) 0.90

Cystic fibrosis: beyond the gene to therapy. J Pediatr (1992) 0.89

Regional expression of CFTR in developing human respiratory tissues. Am J Respir Cell Mol Biol (1994) 0.89

Hypoxia-induced sympathetic inhibition of the fetal plasma insulin response to hyperglycemia. Diabetes (1993) 0.89

Culture of sweat gland epithelial cells from normal individuals and patients with cystic fibrosis. In Vitro Cell Dev Biol (1985) 0.88

Linkage of DNA probe B79a (D7S13) to cystic fibrosis. Am J Hum Genet (1987) 0.88

Human cDNA clones that modify radiomimetic sensitivity of ataxia-telangiectasia (group A) cells. Somat Cell Mol Genet (1995) 0.87

Undergraduate education in family medicine. J Fam Pract (1977) 0.87