Published in Br J Cancer on December 01, 1974
Cytotoxicity of Ro-07-0582; enhancement by hyperthermia and protection by cysteamine. Br J Cancer (1977) 1.86
Studies with bleomycin and misonidazole on aerated and hypoxic cells. Br J Cancer (1978) 1.61
Hypoxic cell radiosensitizers and local control by X-ray of a transplanted tumour in mice. Br J Cancer (1977) 1.31
Radiosensitization by misonidazole (Ro-07-0582) of fractionated X-rays in a murine tumour. Br J Cancer Suppl (1978) 1.02
Enhancement of local tumour control by misonidazole and hyperthermia. Br J Cancer Suppl (1978) 0.98
New developments in radiation therapy for head and neck cancer: intensity-modulated radiation therapy and hypoxia targeting. Semin Oncol (2008) 0.98
Radiosensitizing and cytocidal effects on hypoxic cells of RO-07-0582, and repair of x-ray injury, in an experimental mouse tumour. Br J Cancer (1977) 0.97
Oncogenic transformation in vitro by the hypoxic cell sensitizer misonidazole. Br J Cancer (1978) 0.91
Synthesis and characterization of a hypoxia-sensitive MRI probe. Chemistry (2012) 0.78
A novel hypoxia-dependent 2-nitroimidazole KIN-841 inhibits tumour-specific angiogenesis by blocking production of angiogenic factors. Br J Cancer (2003) 0.78
Further investigations of the effects of the hypoxic-cell radiosensitizer, Ro-07-0582, on local control of a mouse tumour. Br J Cancer (1977) 0.77
Modest radiosensitization of solid tumours in C3H mice by the hypoxic cell radiosensitizer NDPP. Br J Cancer (1975) 0.75
A comparison of the effects of tumour growth delay of fractionated and single dose irradiation when administered with misonidazole (Ro-07-0582). Br J Cancer Suppl (1978) 0.75
The histological structure of some human lung cancers and the possible implications for radiotherapy. Br J Cancer (1955) 10.49
Chemical radiosensitization of hypoxic cells. Br Med Bull (1973) 2.10
Letter: "High-dose" metronidazole: a preliminary pharmacological study prior to its investigational use in clinical radiotherapy trials. Br J Radiol (1974) 1.87
Metronidazole ("Flagyl"). A radiosensitizer of hypoxic cells. Br J Radiol (1974) 1.68
Effectiveness of nitrofuran derivatives in sensitizing hypoxic mammalian cells to x rays. Br J Radiol (1973) 1.53
Induction of lung tumors and malignant lymphomas in mice by metronidazole. J Natl Cancer Inst (1972) 1.24
Current aspects of radiobiology as applied to radiotherapy. Clin Radiol (1972) 1.03
[Selective alterations of Purkinje cells in the dog after oral administration of high doses of nitroimidazole derivatives (author's transl)]. Verh Dtsch Ges Pathol (1972) 1.02
Carcinogenicity of 5-nitrofurans, 5-nitroimidazoles, 4-nitrobenzenes, and related compounds. J Natl Cancer Inst (1973) 0.89
Preferential sensitization of hypoxic cells to radiation in vivo. Nat New Biol (1972) 0.87
A comparison of the response of tumour and normal tissue in the mouse exposed to single doses of fast neutrons or electrons. Br J Radiol (1970) 0.86
Studies of the toxicity and radiosensitising activity of triacetoneamine-N-oxyl in mice. Br J Radiol (1970) 0.86
The number of patients required in a clinical trial. Br J Radiol (1971) 3.85
Clinical testing of the radiosensitiser Ro-07-0582. I. Dose tolerance, serum and tumour concentrations. Clin Radiol (1976) 3.55
A simple analytic derivation suggests that prostate cancer alpha/beta ratio is low. Int J Radiat Oncol Biol Phys (2001) 2.67
Serum concentration measurements in man of the radiosensitizer Ro-07-0582: some preliminary results. Br J Cancer (1975) 2.39
Radiosensitizers of hypoxic cells in solid tumors. Cancer Treat Rev (1976) 2.33
High dose rate intracavitary brachytherapy for carcinoma of the cervix: the Madison system: I. Clinical and radiobiological considerations. Int J Radiat Oncol Biol Phys (1992) 2.24
The adverse effect of treatment prolongation in cervical carcinoma. Int J Radiat Oncol Biol Phys (1995) 2.05
Idealized versus realized overall treatment times. Int J Radiat Oncol Biol Phys (1994) 2.02
Cell kinetic measurements in prostate cancer. Int J Radiat Oncol Biol Phys (1997) 1.83
The effect of multiple small doses of x rays on skin reactions in the mouse and a basic interpretation. Radiat Res (1976) 1.81
Metronidazole (Flagyl): characterization as a cytotoxic drug specific for hypoxic tumour cells. Br J Cancer (1976) 1.77
Demonstration of radiosensitization of hypoxic cells in solid tumours by metronidazole. Br J Radiol (1974) 1.77
Selective boosting of tumor subvolumes. Int J Radiat Oncol Biol Phys (2000) 1.68
Metronidazole ("Flagyl"). A radiosensitizer of hypoxic cells. Br J Radiol (1974) 1.68
Postoperative vaginal cuff irradiation using high dose rate remote afterloading: a phase II clinical protocol. Int J Radiat Oncol Biol Phys (1995) 1.64
5-fluorouracil metabolism monitored in vivo by 19F NMR. Br J Cancer (1984) 1.56
North American Contact Dermatitis Group patch test results for the detection of delayed-type hypersensitivity to topical allergens. J Am Acad Dermatol (1998) 1.51
Balsam-related systemic contact dermatitis. J Am Acad Dermatol (2001) 1.50
Final report of the general clinical results of the British Institute of Radiology fractionation study of 3F/wk versus 5F/wk in radiotherapy of carcinoma of the laryngo-pharynx. Br J Radiol (1990) 1.48
Human studies with "high dose" metronidazole: a non-toxic radiosensitizer of hypoxic cells. Br J Cancer (1975) 1.47
Multiple sclerosis with clinical and radiological features of cerebral tumour. J Neurol Neurosurg Psychiatry (1982) 1.45
Caution on the use of altered fractionation for nasopharyngeal carcinoma. Radiother Oncol (1999) 1.43
Alpha, beta, and surviving fraction. Int J Radiat Oncol Biol Phys (1992) 1.40
Radiosensitization of anoxic cells by metronidazole. Br J Radiol (1973) 1.40
Peristomal allergic contact dermatitis due to Gantrez in Stomahesive paste. J Am Acad Dermatol (2000) 1.40
Re-analysis of the time factor in local control by radiotherapy of T3T4 squamous cell carcinoma of the larynx. Int J Radiat Oncol Biol Phys (1991) 1.38
The effect of irradiating a transplanted murine lymphosarcoma on the subsequent development of metastases. Br J Cancer (1973) 1.33
Hypoxic cell radiosensitizers and local control by X-ray of a transplanted tumour in mice. Br J Cancer (1977) 1.31
Hepatic pyruvate kinase. Regulation by glucagon, cyclic adenosine 3'-5'-monophosphate, and insulin in the perfused rat liver. J Biol Chem (1976) 1.31
A modelled comparison of the effects of using different ways to compensate for missed treatment days in radiotherapy. Clin Oncol (R Coll Radiol) (1996) 1.31
Adrenergic control of glucose output and adenosine 3':5'-monophosphate levels in hepatocytes from juvenile and adult rats. J Biol Chem (1979) 1.30
Effect of time, dose, and fractionation on temporal lobe necrosis following radiotherapy for nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys (1998) 1.26
Taxonomy and pathogenicity of Erwinia cacticida sp. nov. Int J Syst Bacteriol (1991) 1.23
A murine model of lip epidermal/mucosal reactions to X-irradiation. Radiother Oncol (1983) 1.21
A review of alpha/beta ratios for experimental tumors: implications for clinical studies of altered fractionation. Int J Radiat Oncol Biol Phys (1985) 1.18
Lentivirus Nef specifically activates Pak2. J Virol (2000) 1.18
Electron affinic sensitization. II. Para-nitroacetophenone: a radiosensitizer for anoxic bacterial and mammalian cells. Int J Radiat Biol Relat Stud Phys Chem Med (1971) 1.17
Optimum fractionation of the C3H mouse mammary carcinoma using x-rays, the hypoxic-cell radiosensitizer Ro-07-0582, or fast neutrons. Int J Radiat Oncol Biol Phys (1977) 1.16
Changes in mouse blood pressure, tumor blood flow, and core and tumor temperatures following nembutal or urethane anesthesia. Radiology (1976) 1.15
Non-small cell lung tumors repopulate rapidly during radiation therapy. Int J Radiat Oncol Biol Phys (2000) 1.14
The effects of standard care counseling or telephone/in-person counseling on beliefs, knowledge, and behavior related to mammography screening. Oncol Nurs Forum (2001) 1.14
The amphotropic murine leukemia virus receptor gene encodes a 71-kilodalton protein that is induced by phosphate depletion. J Virol (1997) 1.13
Colorectal cancer screening beliefs. Focus groups with first-degree relatives. Cancer Pract (2000) 1.13
Hypoxic cell sensitization by misonidazole in vivo and in vitro. Br J Radiol (1978) 1.12
Radiation sensitization and chemopotentiation: RSU 1069, a compound more efficient than misonidazole in vitro and in vivo. Br J Cancer (1984) 1.11
Repair in mouse lung between multiple small doses of X rays. Radiat Res (1983) 1.09
Biological properties and response to x-rays of first-generation transplants of spontaneous mammary carcinomas in C3H mice. Int J Radiat Biol Relat Stud Phys Chem Med (1975) 1.09
Summary of general discussion on radiotherapeutic aspects of the clinical application of fast neutrons. Eur J Cancer (1971) 1.08
Fractionation factors for late effects in head and neck cancers. Int J Radiat Oncol Biol Phys (1992) 1.07
Deformity of the labyrinth and internal auditory meatus in congenital deafness. Br J Radiol (1975) 1.06
Schistosoma mansoni in the spinal cord: a correlation between operative and radiological findings. J Neurol Neurosurg Psychiatry (1987) 1.06
Review: total doses in fractionated radiotherapy--implications of new radiobiological data. Int J Radiat Biol Relat Stud Phys Chem Med (1984) 1.06
The incidence of lung metastases in C3H mice after treatment of implanted solid tumours with x-rays or surgery. Br J Cancer (1974) 1.05
A metabolite of the 2-nitroimidazole misonidazole with radiosensitizing properties. Int J Radiat Biol Relat Stud Phys Chem Med (1978) 1.05
Acute hormonal control of pyruvate kinase and lactate formation in the isolated rat hepatocyte. Arch Biochem Biophys (1978) 1.04
Vascular targeting of solid tumours: a major 'inverse' volume-response relationship following combretastatin A-4 phosphate treatment of rat rhabdomyosarcomas. Eur J Cancer (2000) 1.04
Hypoxic cell sensitisers in radiotherapy. Lancet (1976) 1.03
Current aspects of radiobiology as applied to radiotherapy. Clin Radiol (1972) 1.03
Skin reactions in mice after multifraction x-irradiation. Int J Radiat Biol Relat Stud Phys Chem Med (1974) 1.03
The effect of radiation on tumour growth delay, cell survival and cure of the animal using a single tumour system. Br J Radiol (1977) 1.02
Radiosensitization by misonidazole (Ro-07-0582) of fractionated X-rays in a murine tumour. Br J Cancer Suppl (1978) 1.02
Microbial colonization of injured cactus tissue (Stenocereus gummosus) and its relationship to the ecology of cactophilic Drosophila mojavensis. Appl Environ Microbiol (1989) 1.02
High dose rate intracavitary brachytherapy for carcinoma of the cervix: the Madison system: II. Procedural and physical considerations. Int J Radiat Oncol Biol Phys (1992) 1.02
Dose-response relationships for human tumors: implications for clinical trials of dose modifying agents. Int J Radiat Oncol Biol Phys (1984) 1.01
Confirmation of improved local-regional control with altered fractionation in head and neck cancer. Int J Radiat Oncol Biol Phys (2000) 1.01
Application of robotic stereotactic radiotherapy to peripheral stage I non-small cell lung cancer with curative intent. Clin Oncol (R Coll Radiol) (2009) 0.99
Development and validation of a Structured Telephone Interview for Dementia Assessment (STIDA): the NIMH Genetics Initiative. J Geriatr Psychiatry Neurol (1997) 0.99
Potentiation in vivo of melphalan activity by nitroimidazole compounds. Int J Radiat Oncol Biol Phys (1982) 0.99
The prediction of late rectal complications in patients treated with high dose-rate brachytherapy for carcinoma of the cervix. Int J Radiat Oncol Biol Phys (1997) 0.99
RSU 1069, a nitroimidazole containing an aziridine group. Bioreduction greatly increases cytotoxicity under hypoxic conditions. Biochem Pharmacol (1986) 0.98
The measurement of blood perfusion in experimental tumors by uptake of 86Rb. Cancer Res (1974) 0.98
Induction by alkaloids and phenobarbital of Family 4 Cytochrome P450s in Drosophila: evidence for involvement in host plant utilization. Mol Gen Genet (1998) 0.98
Radiosensitizing and cytocidal effects on hypoxic cells of RO-07-0582, and repair of x-ray injury, in an experimental mouse tumour. Br J Cancer (1977) 0.97
Influence of in vitro assay conditions on the assessment of radiobiological parameters of the MT tumour. Br J Radiol (1980) 0.97
Alternate binding of actin and calmodulin to multiple sites on dystrophin. J Biol Chem (1995) 0.97
Radiosensitization in vivo: a study with an homologous series of 2-nitroimidazoles. Int J Radiat Biol Relat Stud Phys Chem Med (1983) 0.97
A review of hypoxic cell radiosensitization in experimental tumors. Pharmacol Ther (1979) 0.97
A drug for improved radiosensitization in radiotherapy. Br J Cancer (1980) 0.96
The effect of overall treatment time in radiotherapy for localized prostate carcinoma. Int J Radiat Oncol Biol Phys (1991) 0.96
Repair in mouse lung for up to 20 fractions of X rays or neutrons. Br J Radiol (1985) 0.96
WR-2721 protection of pneumonitis and fibrosis in mouse lung after single doses of x rays. Int J Radiat Oncol Biol Phys (1984) 0.95
Potential for increasing the differential response between tumors and normal tissues: can proliferation rate be used? Int J Radiat Oncol Biol Phys (1986) 0.95
Radiosensitization of C3H mouse mammary tumours using fractionated doses of x rays with the drug Ro-07-0582. Br J Radiol (1976) 0.95
Sustained progression-free survival with weekly paclitaxel and bevacizumab in recurrent ovarian cancer. Gynecol Oncol (2009) 0.94
RSU 1069, a 2-nitroimidazole containing an alkylating group: high efficiency as a radio- and chemosensitizer in vitro and in vivo. Int J Radiat Oncol Biol Phys (1984) 0.94
Radiosensitization of solid tumors by nitroimidazoles. Int J Radiat Oncol Biol Phys (1978) 0.94
The first James Kirk memorial lecture. What next in fractionated radiotherapy? Br J Cancer Suppl (1984) 0.94
Exit doses for lung fields measured by lithium fluoride thermoluminescence. Br J Radiol (1965) 0.93
A new incomplete-repair model based on a 'reciprocal-time' pattern of sublethal damage repair. Acta Oncol (1999) 0.93
The effect of anaesthetics on blood perfusion in transplanted mouse tumours. Br J Cancer (1975) 0.93
Optimum fractionation in X-ray treatment of C3H mouse mammary tumours. Br J Radiol (1974) 0.93