Published in J Biol Chem on June 25, 1979
Mutator strains of Escherichia coli, mutD and dnaQ, with defective exonucleolytic editing by DNA polymerase III holoenzyme. Proc Natl Acad Sci U S A (1983) 2.83
The replication initiator protein of plasmid pT181 has sequence-specific endonuclease and topoisomerase-like activities. Proc Natl Acad Sci U S A (1985) 2.59
The NS-1 polypeptide of minute virus of mice is covalently attached to the 5' termini of duplex replicative-form DNA and progeny single strands. J Virol (1988) 2.34
A geminivirus replication protein is a sequence-specific DNA binding protein. Plant Cell (1992) 1.61
Initiation and termination of phage f1 plus-strand synthesis. Proc Natl Acad Sci U S A (1982) 1.60
Asymmetric resolution of a parvovirus palindrome in vitro. J Virol (1993) 1.48
In vivo resolution of circular plasmids containing concatemer junction fragments from minute virus of mice DNA and their subsequent replication as linear molecules. J Virol (1992) 1.45
Nucleotide sequences at the phi X gene A protein cleavage site in replicative form I DNAs of bacteriophages U3, G14, and alpha 3. J Virol (1982) 1.39
Morphogenesis of phi X174: in vitro synthesis of infectious phage from purified viral components. Proc Natl Acad Sci U S A (1981) 1.34
Conservation of the primosome in successive stages of phi X174 DNA replication. Proc Natl Acad Sci U S A (1981) 1.33
Identification and characterization of a protein covalently bound to DNA of minute virus of mice. J Virol (1986) 1.26
A defective phage system reveals bacteriophage T4 replication origins that coincide with recombination hot spots. Proc Natl Acad Sci U S A (1985) 1.12
Host and phi X 174 mutations affecting the morphogenesis or stabilization of the 50S complex, a single-stranded DNA synthesizing intermediate. Genetics (1995) 1.06
In vitro synthesis of bacteriophage phi X174 by purified components. Proc Natl Acad Sci U S A (1983) 1.05
The nuclease specificity of the bacteriophage phi X174 A* protein. Nucleic Acids Res (1981) 1.04
Construction and characterization of recombinant plasmid DNAs containing sequences of the origin of bacteriophage phi X174 DNA replication. Nucleic Acids Res (1981) 1.03
Replication of duplex DNA of phage phi X174 reconstituted with purified enzymes. Proc Natl Acad Sci U S A (1980) 1.00
Cleavage of single-stranded DNA by the varphiX174 A protein: The A-single-stranded DNA covalent linkage. Proc Natl Acad Sci U S A (1984) 1.00
Cleavage of phi X174 single-stranded DNA by gene A protein and formation of a tight protein-DNA complex. J Virol (1980) 0.97
Enzymatic techniques for the isolation of random single-base substitutions in vitro at high frequency. Proc Natl Acad Sci U S A (1984) 0.97
Studies of the recognition sequence of phi X174 gene A protein. Cleavage site of phi X gene A protein in St-1 RFI DNA. Nucleic Acids Res (1980) 0.94
The A* protein of phi X174 is an inhibitor of DNA replication. Nucleic Acids Res (1981) 0.92
Bacteriophage phi X174 A protein cleaves single-stranded DNA and binds to it covalently through a tyrosyl-dAMP phosphodiester bond. J Virol (1985) 0.92
Nonhomologous recombination in the parvovirus chromosome: role for a CTATTTCT motif. Mol Cell Biol (1986) 0.89
Uncoupling of the DNA topoisomerase and replication activities of an initiator protein. Proc Natl Acad Sci U S A (1992) 0.88
Effect of SSB protein on cleavage of single-stranded DNA by phi X gene A protein and A* protein. Nucleic Acids Res (1986) 0.87
Mechanism of replication of bacteriophage phi X174 XIX. Initiation of phi X174 viral strand DNA synthesis at internal sites on the genome. J Virol (1982) 0.85
A single amino acid substitution reduces the superhelicity requirement of a replication initiator protein. Nucleic Acids Res (1992) 0.81
Escherichia coli host factor required specifically for the phi X174 stage III reaction: in vitro identification and partial purification. Proc Natl Acad Sci U S A (1982) 0.78
Rolling-circle replication of UV-irradiated duplex DNA in the phi X174 replicative-form----single-strand replication system in vitro. J Bacteriol (1989) 0.77
Gene A protein cleavage of recombinant plasmids containing the phi X174 replication origin. Nucleic Acids Res (1984) 0.77
Enzymatic synthesis of deoxyribonucleic acid. XXXIV. Termination of chain growth by a 2',3'-dideoxyribonucleotide. Biochemistry (1969) 60.64
A minute circular DNA from Escherichia coli 15. Proc Natl Acad Sci U S A (1968) 9.91
Enzymatic synthesis of deoxyribonucleic acid. XXXII. Replication of duplex deoxyribonucleic acid by polymerase at a single strand break. J Biol Chem (1970) 9.31
The metabolism of very low density lipoprotein proteins. I. Preliminary in vitro and in vivo observations. Biochim Biophys Acta (1972) 9.02
RNA synthesis initiates in vitro conversion of M13 DNA to its replicative form. Proc Natl Acad Sci U S A (1972) 8.09
The dnaA protein complex with the E. coli chromosomal replication origin (oriC) and other DNA sites. Cell (1984) 7.27
A possible role for RNA polymerase in the initiation of M13 DNA synthesis. Proc Natl Acad Sci U S A (1971) 6.71
Enzymatic synthesis of deoxyribonucleic acid. XXV. Purification and properties of deoxyribonucleic acid polymerase induced by infection with phage T4. J Biol Chem (1968) 6.42
Duplex opening by dnaA protein at novel sequences in initiation of replication at the origin of the E. coli chromosome. Cell (1988) 6.42
Enzymatic synthesis of deoxyribonucleic acid. 36. A proofreading function for the 3' leads to 5' exonuclease activity in deoxyribonucleic acid polymerases. J Biol Chem (1972) 6.15
Initiation of DNA synthesis: synthesis of phiX174 replicative form requires RNA synthesis resistant to rifampicin. Proc Natl Acad Sci U S A (1972) 5.74
Enzymatic replication of the origin of the Escherichia coli chromosome. Proc Natl Acad Sci U S A (1981) 5.20
Deoxyuridine triphosphatase of Escherichia coli. Purification, properties, and use as a reagent to reduce uracil incorporation into DNA. J Biol Chem (1978) 5.16
ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. III. THE INCORPORATION OF PYRIMIDINE AND PURINE ANALOGUES INTO DEOXYRIBONUCLEIC ACID. Proc Natl Acad Sci U S A (1958) 4.99
The deoxyribonucleic acid unwinding protein of Escherichia coli. Properties and functions in replication. J Biol Chem (1975) 4.87
Inorganic polyphosphate is needed for swimming, swarming, and twitching motilities of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (2000) 4.82
Active center of DNA polymerase. Science (1969) 4.47
DNA polymerase III holoenzyme of Escherichia coli. Purification and resolution into subunits. J Biol Chem (1977) 4.41
phiX174 cistron A protein is a multifunctional enzyme in DNA replication. Proc Natl Acad Sci U S A (1977) 4.31
A mechanism of duplex DNA replication revealed by enzymatic studies of phage phi X174: catalytic strand separation in advance of replication. Proc Natl Acad Sci U S A (1977) 4.12
A model for initiation at origins of DNA replication. Cell (1988) 3.95
Origin of proteins in sporulation. Annu Rev Biochem (1968) 3.86
Multienzyme systems of DNA replication. Science (1974) 3.66
Extensive unwinding of the plasmid template during staged enzymatic initiation of DNA replication from the origin of the Escherichia coli chromosome. Cell (1986) 3.51
Purified dnaA protein in initiation of replication at the Escherichia coli chromosomal origin of replication. Proc Natl Acad Sci U S A (1983) 3.40
Role of inorganic polyphosphate in promoting ribosomal protein degradation by the Lon protease in E. coli. Science (2001) 3.35
Primase, the dnaG protein of Escherichia coli. An enzyme which starts DNA chains. J Biol Chem (1978) 3.34
Biochemical studies of bacterial sporulation and germination. XXII. Energy metabolism in early stages of germination of Bacillus megaterium spores. J Biol Chem (1970) 3.34
ATP activates dnaA protein in initiating replication of plasmids bearing the origin of the E. coli chromosome. Cell (1987) 3.32
Conversion of the M13 viral single strand to the double-stranded replicative forms by purified proteins. J Biol Chem (1974) 3.25
Novel assay reveals multiple pathways regulating stress-induced accumulations of inorganic polyphosphate in Escherichia coli. J Bacteriol (1998) 3.20
Mutant single-strand binding protein of Escherichia coli: genetic and physiological characterization. J Bacteriol (1979) 3.14
Enzymatic synthesis of DNA, XXIV. Synthesis of infectious phage phi-X174 DNA. Proc Natl Acad Sci U S A (1967) 3.09
Polyphosphate kinase from Escherichia coli. Purification and demonstration of a phosphoenzyme intermediate. J Biol Chem (1990) 3.01
Enzymatic synthesis of DNA. 23. Synthesis of circular replicative form of phage phi-X174 DNA. Proc Natl Acad Sci U S A (1967) 3.00
dnaG gene product, a rifampicin-resistant RNA polymerase, initiates the conversion of a single-stranded coliphage DNA to its duplex replicative form. J Biol Chem (1975) 2.99
Biochemical studies of bacterial sporulation and germination. XVII. Sulfhydryl and disulfide levels in dormancy and germination. J Bacteriol (1969) 2.97
An active fragment of DNA polymerase produced by proteolytic cleavage. Biochem Biophys Res Commun (1969) 2.96
High density lipoprotein metabolism. J Lipid Res (1984) 2.85
Initiation of deoxyribonucleic acid synthesis. VII. A unique location of the gap in the M13 replicative duplex synthesized in vitro. J Biol Chem (1974) 2.85
Enzymatic synthesis of deoxyribonucleic acid. XXX. Binding of triphosphates to deoxyribonucleic acid polymerase. J Biol Chem (1969) 2.80
Translational frameshifting generates the gamma subunit of DNA polymerase III holoenzyme. Proc Natl Acad Sci U S A (1990) 2.78
Inorganic polyphosphate supports resistance and survival of stationary-phase Escherichia coli. J Bacteriol (1996) 2.74
Transcriptional activation of initiation of replication from the E. coli chromosomal origin: an RNA-DNA hybrid near oriC. Cell (1988) 2.68
Stimulation of T4 bacteriophage DNA polymerase by the protein product of T4 gene 32. J Mol Biol (1971) 2.67
An Escherichia coli replication protein that recognizes a unique sequence within a hairpin region in phi X174 DNA. Proc Natl Acad Sci U S A (1980) 2.67
Replication initiated at the origin (oriC) of the E. coli chromosome reconstituted with purified enzymes. Cell (1984) 2.63
An Escherichia coli mutant defective in single-strand binding protein is defective in DNA replication. Proc Natl Acad Sci U S A (1979) 2.62
Biochemical studies of bacterial sporulation and germination. 8. Patterns of enzyme development during growth and sporulation of Baccillus subtilis. J Biol Chem (1968) 2.60
PRODUCTION AND TREATMENT OF GRANULOCYTOPENIA AND ANEMIA IN RATS FED SULFONAMIDES IN PURIFIED DIETS. Science (1943) 2.54
Polyphosphate kinase is essential for biofilm development, quorum sensing, and virulence of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (2000) 2.52
A membrane-bound phospholipase A1 purified from Escherichia coli. Biochemistry (1971) 2.51
Ten proteins required for conversion of phiX174 single-stranded DNA to duplex form in vitro. Resolution and reconstitution. J Biol Chem (1975) 2.48
In vitro assembly of a prepriming complex at the origin of the Escherichia coli chromosome. J Biol Chem (1987) 2.47
Unique primed start of phage phi X174 DNA replication and mobility of the primosome in a direction opposite chain synthesis. Proc Natl Acad Sci U S A (1981) 2.44
Nobel laureates' letter to President Bush. Washington Post (2001) 2.43
Inorganic polyphosphate in mammalian cells and tissues. J Biol Chem (1995) 2.43
A new form of DNA polymerase 3 and a copolymerase replicate a long, single-stranded primer-template. Proc Natl Acad Sci U S A (1973) 2.42
An exopolyphosphatase of Escherichia coli. The enzyme and its ppx gene in a polyphosphate operon. J Biol Chem (1993) 2.41
Founder BRCA1 and BRCA2 mutations in Ashkenazi Jews in Israel: frequency and differential penetrance in ovarian cancer and in breast-ovarian cancer families. Am J Hum Genet (1997) 2.31
Deoxyribonucleic acid polymerase: two distinct enzymes in one polypeptide. I. A proteolytic fragment containing the polymerase and 3' leads to 5' exonuclease functions. J Biol Chem (1972) 2.29
ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. IV. LINKAGE OF SINGLE DEOXYNUCLEOTIDES TO THE DEOXYNUCLEOSIDE ENDS OF DEOXYRIBONUCLEIC ACID. Proc Natl Acad Sci U S A (1958) 2.27
Guanosine tetra- and pentaphosphate promote accumulation of inorganic polyphosphate in Escherichia coli. J Biol Chem (1997) 2.27
RNase H confers specificity in the dnaA-dependent initiation of replication at the unique origin of the Escherichia coli chromosome in vivo and in vitro. Proc Natl Acad Sci U S A (1984) 2.26
Biochemical studies of bacterial sporulation and germaination. VII. Protein turnover during sporulation of Bacillus subtilis. J Biol Chem (1968) 2.26
Protein HU in the enzymatic replication of the chromosomal origin of Escherichia coli. Proc Natl Acad Sci U S A (1984) 2.25
Inorganic polyphosphate in Escherichia coli: the phosphate regulon and the stringent response. J Bacteriol (1998) 2.21
ATP utilization by rep protein in the catalytic separation of DNA strands at a replicating fork. J Biol Chem (1978) 2.20
The polyphosphate kinase gene of Escherichia coli. Isolation and sequence of the ppk gene and membrane location of the protein. J Biol Chem (1992) 2.20
The polymerase subunit of DNA polymerase III of Escherichia coli. II. Purification of the alpha subunit, devoid of nuclease activities. J Biol Chem (1985) 2.19
Inorganic polyphosphate and the induction of rpoS expression. Proc Natl Acad Sci U S A (1997) 2.19
The mechanism of replication of phiX174 DNA. XII. Non-random location of gaps in nascent phiX174 RF II DNA. J Mol Biol (1975) 2.18
ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. V. CHEMICAL COMPOSITION OF ENZYMATICALLY SYNTHESIZED DEOXYRIBONUCLEIC ACID. Proc Natl Acad Sci U S A (1958) 2.18
Enzymatic synthesis of deoxyribonucleic acid. XXIX. Hydrolysis of deoxyribonucleic acid from the 5' terminus by an exonuclease function of deoxyribonucleic acid polymerase. J Biol Chem (1969) 2.17
An enzyme system for replication of duplex circular DNA: the replicative form of phage phi X174. Proc Natl Acad Sci U S A (1976) 2.16
A novel binding protein of the origin of the Escherichia coli chromosome. J Biol Chem (1993) 2.12
Enzymatic replication of viral and complementary strands of duplex DNA of phage phiX174 proceeds by seprate mechanisms. Proc Natl Acad Sci U S A (1976) 2.12
A single nucleotide polymorphism in the RAD51 gene modifies cancer risk in BRCA2 but not BRCA1 carriers. Proc Natl Acad Sci U S A (2001) 2.09
Enzymic synthesis of DNA. 33. Hydrolysis of a 5'-triphosphate-terminated polynucleotide in the active center of DNA polymerase. J Mol Biol (1969) 2.09
Initiation of enzymatic replication at the origin of the Escherichia coli chromosome: primase as the sole priming enzyme. Proc Natl Acad Sci U S A (1985) 2.08
Biochemical studies of bacterial sporulation and germination. VI. Origin of spore core and coat proteins. J Biol Chem (1968) 2.06
The gene for a major exopolyphosphatase of Saccharomyces cerevisiae. J Bacteriol (1995) 2.06
Biochemical studies of bacterial sporulation and germination. XIV. Phospholipids in Bacillus megaterium. J Bacteriol (1969) 2.06
Migration of Escherichia coli dnaB protein on the template DNA strand as a mechanism in initiating DNA replication. Proc Natl Acad Sci U S A (1977) 2.03
The RNA primer synthesized by primase to initiate phage G4 DNA replication. J Biol Chem (1978) 2.03
The NIH did it! Science (1997) 2.02
Cardiolipin activation of dnaA protein, the initiation protein of replication in Escherichia coli. J Biol Chem (1988) 2.02
Opening of the replication origin of Escherichia coli by DnaA protein with protein HU or IHF. J Biol Chem (1992) 2.01
Polynucleotide cellulose as a substrate for a polynucleotide ligase induced by phage T4. Biochem Biophys Res Commun (1967) 2.00
Escherichia coli replication termination protein impedes the action of helicases. Proc Natl Acad Sci U S A (1989) 2.00
Helicase action of dnaB protein during replication from the Escherichia coli chromosomal origin in vitro. J Biol Chem (1987) 2.00
A DNA replication enhancer in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1990) 1.98
Mechanism of dnaB protein action. I. Crystallization and properties of dnaB protein, an essential replication protein in Escherichia coli. J Biol Chem (1981) 1.96
Initiation of deoxyribonucleic acid synthesis. IV. Incorporation of the ribonucleic acid primer into the phage replicative form. J Biol Chem (1973) 1.96
Biochemical studies of bacterial sporulation and germination. 18. Free amino acids in spores. J Biol Chem (1970) 1.94
Purification of the rep protein of Escherichia coli. An ATPase which separates duplex DNA strands in advance of replication. J Biol Chem (1978) 1.94