Published in Proc Natl Acad Sci U S A on May 01, 1973
HLA-A2-peptide complexes: refolding and crystallization of molecules expressed in Escherichia coli and complexed with single antigenic peptides. Proc Natl Acad Sci U S A (1992) 5.02
Structure of HLA antigens: amino-acid and carbohydrate compositions and NH2-terminal sequences of four antigen preparations. Proc Natl Acad Sci U S A (1976) 2.71
The small subunit of HL-A antigens is beta 2-microglobulin. J Exp Med (1973) 2.68
Highly purified papain-solubilized HL-A antigens contain beta2-microglobulin. Proc Natl Acad Sci U S A (1974) 2.66
Structure of crossreactive human histocompatibility antigens HLA-A28 and HLA-A2: possible implications for the generation of HLA polymorphism. Proc Natl Acad Sci U S A (1982) 2.36
Multiple common properties of human beta2-microglobulin and the common portion fragment derived from HL-A antigen molecules. Proc Natl Acad Sci U S A (1973) 2.08
Comparison of amino acid sequences of two human histocompatibility antigens, HLA-A2 and HLA-B7: location of putative alloantigenic sites. Proc Natl Acad Sci U S A (1979) 1.94
Detergent-soluble HLA antigens contain a hydrophilic region at the COOH-terminus and a penultimate hydrophobic region. Proc Natl Acad Sci U S A (1976) 1.82
Immunological identity of the small subunit of HL-A antigens and beta2-microglobulin and its turnover on the cell membrane. Proc Natl Acad Sci U S A (1974) 1.80
Evolutionary relationship between immunoglobulins and transplantation antigens. Proc Natl Acad Sci U S A (1975) 1.62
Phosphorylation in vivo and in vitro of human histocompatibility antigens (HLA-A and HLA-B) in the carboxy-terminal intracellular domain. Proc Natl Acad Sci U S A (1978) 1.50
Complete amino acid sequence of murine beta 2-microglobulin: structural evidence for strain-related polymorphism. Proc Natl Acad Sci U S A (1981) 1.42
Partial purification of detergent-soluble HL-A antigen and its cleavage by papain. Proc Natl Acad Sci U S A (1974) 1.41
Reconstitution of purified detergent-soluble HLA-A and HLA-B antigens into phospholipid vesicles. Proc Natl Acad Sci U S A (1978) 1.40
Plasma and urinary levels of beta2 microglobulin in rheumatoid arthritis. Ann Rheum Dis (1978) 1.35
Heterogeneity of HL-A antigen preparations is due to variable sialic acid content. Proc Natl Acad Sci U S A (1974) 1.12
HLA-B locus polymorphism: studies with a specific hybridization probe. Proc Natl Acad Sci U S A (1985) 1.12
Relationship between HL-A antigens and beta-2-microglobulin as studied by immunofluorescence on the lymphocyte membrane. J Exp Med (1974) 1.06
Analysis of Major Histocompatibility Complex (MHC) Immunopeptidomes Using Mass Spectrometry. Mol Cell Proteomics (2015) 1.05
Common antigenic structures of HL-A antigens. II. Small fragments derived from papain-solubilized HL-A antigen molecules. Immunology (1974) 1.05
Linkage of beta 2-microglobulin and ly-m11 by molecular cloning and DNA-mediated gene transfer. Proc Natl Acad Sci U S A (1983) 1.04
Common antigenic structures of HL-A antigens. IV. HL-A common portion fragment isolated from spent culture medium of human lymphoid cell lines. Immunology (1974) 1.03
Beta 2-microglobulin is selectively associated with H-2 and TL alloantigens on murine lymphoid cells. J Exp Med (1976) 1.02
beta2-Microglobulin production by highly purified human T and B lymphocytes in cell culture stimulated with various mitogens. Immunology (1979) 0.98
Immunological and chemical purity of papain-solubilized HL-A antigens. Proc Natl Acad Sci U S A (1975) 0.97
Soluble HLA class I antigen secretion by normal lymphocytes: relationship with cell activation and effect of interferon-gamma. Clin Exp Immunol (1990) 0.90
Proteolysis of lymphocytic surface immunoglobulin. Immunology (1977) 0.84
Cell surface expression of beta 2-microglobulin (beta 2m) correlates with stages of differentiation in B cell tumours. J Clin Pathol (1987) 0.81
Synovial fluid beta 2 microglobulin and hydroxyproline fractions in rheumatoid arthritis and nonautoimmune arthropathies. Ann Rheum Dis (1980) 0.81
Evidence for a membrane carrier molecule common to embryonal and tumour-specific antigenic determinants expressed by a mouse transplantable tumour. Immunology (1975) 0.80
Cellular cooperation in lymphocyte activation. II. Cooperative response of human peripheral T and B lymphocytes to rabbit anti-human beta 2-microglobulin. Clin Exp Immunol (1979) 0.80
Synthesis and secretion of alpha 1-microglobulin by human lymphocytes. Clin Exp Immunol (1979) 0.79
Evidence for tryosine peptide homologies in the HLA antigens system. Proc Natl Acad Sci U S A (1975) 0.75
Rat transplantation antigens. V. A variation of the KCl-method releasing low molecular weight antigen. Immunology (1977) 0.75
The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis. J Biol Chem (1969) 142.11
The estimation of polypeptide chain molecular weights by gel filtration in 6 M guanidine hydrochloride. J Biol Chem (1969) 4.77
APPLICATIONS OF ISO-IMMUNE CYTOLYSIS USING RADIOLABELLED TARGET CELLS. Nature (1964) 2.50
Isolation of H-2 alloantigens solubilized by the detergent NP-40. J Immunol (1971) 2.26
Salt extraction of soluble HL-A antigens. Science (1971) 2.18
HL-A substances from human spleens. Nature (1968) 1.31
HL-A antigens from hematopoietic cell lines: molecular size and electrophoretic mobility. J Immunol (1971) 1.28
Transplantation antigens from human spleens. Nature (1968) 1.20
Involvement of carbohydrate in the immunochemical determinant area of HL-A substances. Nat New Biol (1971) 1.17
The effect of enzyme inhibitors on the solubilization of HL-A antigens with 3 M KCl. Transplantation (1972) 1.11
Separation of HL-A transplantation antigen specificities. Transplantation (1970) 0.96
Structure of the human class I histocompatibility antigen, HLA-A2. Nature (1987) 14.54
The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens. Nature (1987) 12.43
Mechanism of action of penicillins: a proposal based on their structural similarity to acyl-D-alanyl-D-alanine. Proc Natl Acad Sci U S A (1965) 10.20
Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature (1993) 8.75
Identification of a putative second T-cell receptor. Nature (1986) 7.90
Interaction of penicillin with the bacterial cell: penicillin-binding proteins and penicillin-sensitive enzymes. Bacteriol Rev (1974) 7.49
Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. Proc Natl Acad Sci U S A (1982) 7.16
Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide. Nature (1994) 7.13
The selective downregulation of class I major histocompatibility complex proteins by HIV-1 protects HIV-infected cells from NK cells. Immunity (1999) 6.80
Epstein-Barr virus receptor of human B lymphocytes is the C3d receptor CR2. Proc Natl Acad Sci U S A (1984) 6.62
Biosynthesis of the peptidoglycan of bacterial cell walls. 8. Peptidoglycan transpeptidase and D-alanine carboxypeptidase: penicillin-sensitive enzymatic reaction in strains of Escherichia coli. J Biol Chem (1968) 6.42
Penicillin-binding proteins and the mechanism of action of beta-lactam antibiotics. Annu Rev Biochem (1983) 6.24
Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein. Cell (1995) 5.82
Major histocompatibility antigens: the human (HLA-A, -B, -C) and murine (H-2K, H-2D) class I molecules. Cell (1981) 5.81
Mechanism of action and development of resistance to a new amidino penicillin. J Bacteriol (1974) 5.47
Genes regulating HLA class I antigen expression in T-B lymphoblast hybrids. Immunogenetics (1985) 5.30
Interaction between CD4 and class II MHC molecules mediates cell adhesion. Nature (1987) 5.24
Mechanisms of enzymatic bacteriaolysis. Cell walls of bacteri are solubilized by action of either specific carbohydrases or specific peptidases. Science (1967) 5.14
Recombinant human tumor necrosis factor increases mRNA levels and surface expression of HLA-A,B antigens in vascular endothelial cells and dermal fibroblasts in vitro. Proc Natl Acad Sci U S A (1986) 5.03
Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles. J Exp Med (1993) 4.99
Expression of human class II major histocompatibility complex antigens using retrovirus vectors. Proc Natl Acad Sci U S A (1987) 4.84
Recognition of haemagglutinins on virus-infected cells by NKp46 activates lysis by human NK cells. Nature (2001) 4.76
Purification to homogeneity and properties of two D-alanine carboxypeptidases I From Escherichia coli. J Biol Chem (1976) 4.66
Glycopeptide transpeptidase and D-alanine carboxypeptidase: penicillin-sensitive enzymatic reactions. Proc Natl Acad Sci U S A (1966) 4.59
Mechanisms of MHC class I--restricted antigen processing. Annu Rev Immunol (1998) 4.54
HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides. Nature (1992) 4.53
Immune interferon activates multiple class II major histocompatibility complex genes and the associated invariant chain gene in human endothelial cells and dermal fibroblasts. Proc Natl Acad Sci U S A (1984) 4.43
Altered penicillin-binding components in penicillin-resistant mutants of Bacillus subtilis. Proc Natl Acad Sci U S A (1976) 4.41
Glycosylation and the immune system. Science (2001) 4.39
Specificity pockets for the side chains of peptide antigens in HLA-Aw68. Nature (1989) 4.34
Structure of a lipid intermediate in cell wall peptidoglycan synthesis: a derivative of a C55 isoprenoid alcohol. Proc Natl Acad Sci U S A (1967) 4.15
Peptidoglycan transpeptidase and D-alanine carboxypeptidase: penicillin-sensitive enzymatic reactions. Fed Proc (1967) 4.14
Extreme Th1 bias of invariant Valpha24JalphaQ T cells in type 1 diabetes. Nature (1998) 4.10
Distribution of Ia-like molecules on the surface of normal and leukemic human cells. Proc Natl Acad Sci U S A (1976) 4.05
Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size. Nature (1992) 3.85
Biosythesis of the peptidoglycan of bacterial cell walls. II. Phospholipid carriers in the reaction sequence. J Biol Chem (1967) 3.85
The structure of HLA-B27 reveals nonamer self-peptides bound in an extended conformation. Nature (1991) 3.84
Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle. Nature (1992) 3.82
Impaired assembly and transport of HLA-A and -B antigens in a mutant TxB cell hybrid. EMBO J (1986) 3.78
Human lymphocytes bearing T cell receptor gamma/delta are phenotypically diverse and evenly distributed throughout the lymphoid system. J Exp Med (1989) 3.70
Cross-linking of human T cell receptor proteins: association between the T cell idiotype beta subunit and the T3 glycoprotein heavy subunit. Cell (1985) 3.64
HLA-DM induces CLIP dissociation from MHC class II alpha beta dimers and facilitates peptide loading. Cell (1995) 3.64
Enzymatic polymerization of UDP-acetylmuramyl.L-ala.D-glu.L-lys.D-ala.D-ala and UDP-acetylglucosamine by a particulate enzyme from Staphylococcus aureus and its inhibition by antibiotics. Biochem Biophys Res Commun (1964) 3.63
Three-dimensional structure of a human class II histocompatibility molecule complexed with superantigen. Nature (1994) 3.60
Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding. Nature (1990) 3.54
Toll-like receptor 2 (TLR2) and TLR4 differentially activate human dendritic cells. J Biol Chem (2001) 3.49
Co-localization of molecules involved in antigen processing and presentation in an early endocytic compartment. Nature (1990) 3.44
Biosynthesis of the peptidoglycan of bacterial cell walls. I. Utilization of uridine diphosphate acetylmuramyl pentapeptide and uridine diphosphate acetylglucosamine for peptidoglycan synthesis by particulate enzymes from Staphylococcus aureus and Micrococcus lysodeikticus. Arch Biochem Biophys (1966) 3.38
Evidence for extrathymic changes in the T cell receptor gamma/delta repertoire. J Exp Med (1990) 3.38
Analysis of the transcript encoding the latent Epstein-Barr virus nuclear antigen I: a potentially polycistronic message generated by long-range splicing of several exons. Proc Natl Acad Sci U S A (1985) 3.35
Multiple penicillin-binding components in Bacillus subtilis, Bacillus cereus, Staphylococcus aureus, and Escherichia coli. J Biol Chem (1972) 3.32
Simultaneous deletion of D-alanine carboxypeptidase IB-C and penicillin-binding component IV in a mutant of Escherichia coli K12. Proc Natl Acad Sci U S A (1977) 3.31
Cell-free translation of the mRNAs for the heavy and light chains of HLA-A and HLA-B antigens. Proc Natl Acad Sci U S A (1979) 3.29
Promoter switching in Epstein-Barr virus during the initial stages of infection of B lymphocytes. Proc Natl Acad Sci U S A (1990) 3.29
Bacitracin: an inhibitor of the dephosphorylation of lipid pyrophosphate, an intermediate in the biosynthesis of the peptidoglycan of bacterial cell walls. Proc Natl Acad Sci U S A (1967) 3.28
p62, a phosphotyrosine-independent ligand of the SH2 domain of p56lck, belongs to a new class of ubiquitin-binding proteins. J Biol Chem (1996) 3.27
The three-dimensional structure of HLA-B27 at 2.1 A resolution suggests a general mechanism for tight peptide binding to MHC. Cell (1992) 3.27
Glycoproteins of 210,000 and 130,000 m.w. on activated T cells: cell distribution and antigenic relation to components on resting cells and T cell lines. J Immunol (1984) 3.26
Nomenclature for factors of the HLA system, 2010. Tissue Antigens (2010) 3.22
Two genes encoding steroid 21-hydroxylase are located near the genes encoding the fourth component of complement in man. Proc Natl Acad Sci U S A (1985) 3.22
Roles for calreticulin and a novel glycoprotein, tapasin, in the interaction of MHC class I molecules with TAP. Immunity (1996) 3.18
Differential cytokine and chemokine gene expression by human NK cells following activation with IL-18 or IL-15 in combination with IL-12: implications for the innate immune response. J Immunol (1999) 3.18
Penicillin-sensitive enzymes and penicillin-binding components in bacterial cells. Ann N Y Acad Sci (1974) 3.16
Atomic structure of a human MHC molecule presenting an influenza virus peptide. Nature (1992) 3.12
Penicillin-resistant temperature-sensitive mutants of Escherichia coli which synthesize hypo- or hyper-cross-linked peptidoglycan. J Bacteriol (1974) 3.09
Biosynthesis of the peptidoglycan of bacterial cell walls. XIV. Purification and properties of two D-alanine carboxypeptidases from Escherichia coli. J Biol Chem (1968) 3.08
A membrane enzyme from Staphylococcus aureus which catalyzes transpeptidase, carboxypeptidase, and penicillinase activities. J Biol Chem (1978) 3.07
NK susceptibility varies inversely with target cell class I HLA antigen expression. J Immunol (1987) 3.06
The gamma delta T cell receptor. Adv Immunol (1988) 3.06
Modulation of cell surface iron transferrin receptors by cellular density and state of activation. J Supramol Struct (1979) 3.02
Characterization of a monoclonal antibody (4F2) that binds to human monocytes and to a subset of activated lymphocytes. J Immunol (1981) 3.02
Molecular cloning of a human histocompatibility antigen cDNA fragment. Proc Natl Acad Sci U S A (1980) 2.99
Purification and properties of C 55 -isoprenoid alcohol phosphokinase from Staphylococcus aureus. J Biol Chem (1972) 2.95
Characterization of the cell surface heterodimer VLA-4 and related peptides. J Biol Chem (1987) 2.94
HLA-C is the inhibitory ligand that determines dominant resistance to lysis by NK1- and NK2-specific natural killer cells. Proc Natl Acad Sci U S A (1993) 2.91
cDNA clones for the heavy chain of HLA-DR antigens obtained after immunopurification of polysomes by monoclonal antibody. Proc Natl Acad Sci U S A (1982) 2.88
Mutually exclusive use of viral promoters in Epstein-Barr virus latently infected lymphocytes. Proc Natl Acad Sci U S A (1989) 2.88
Human B-cell alloantigens DC1, MT1, and LB12 are identical to each other but distinct from the HLA-DR antigen. Proc Natl Acad Sci U S A (1981) 2.86
Identification of the major penicillin-binding proteins of Escherichia coli as D-alanine carboxypeptidase IA. J Bacteriol (1976) 2.85
A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor. Nat Genet (1999) 2.85
The human natural killer cell immune synapse. Proc Natl Acad Sci U S A (1999) 2.82
Five penicillin-binding components occur in Bacillus subtilis membranes. J Biol Chem (1972) 2.81
Inactivation of D-alanine carboxypeptidase by penicillins and cephalosporins is not lethal in Bacillus subtilis. Proc Natl Acad Sci U S A (1971) 2.80
cDNA clone for the heavy chain of the human B cell alloantigen DC1: strong sequence homology to the HLA-DR heavy chain. Proc Natl Acad Sci U S A (1982) 2.80
A new cluster of genes within the human major histocompatibility complex. Science (1989) 2.76
HLA-DR antigens: structure, separation of subpopulations, gene cloning and function. Immunol Rev (1982) 2.74
Assembly and maturation of HLA-A and HLA-B antigens in vivo. Cell (1979) 2.73
Complete amino acid sequence of a papain-solubilized human histocompatibility antigen, HLA-B7. 2. Sequence determination and search for homologies. Biochemistry (1979) 2.71
Structure of HLA antigens: amino-acid and carbohydrate compositions and NH2-terminal sequences of four antigen preparations. Proc Natl Acad Sci U S A (1976) 2.71
Cloning and mapping of BamHi endonuclease fragments of DNA from the transforming B95-8 strain of Epstein-Barr virus. Proc Natl Acad Sci U S A (1980) 2.69
The small subunit of HL-A antigens is beta 2-microglobulin. J Exp Med (1973) 2.68
Regulation of a transfected human class II major histocompatibility complex gene in human fibroblasts. Proc Natl Acad Sci U S A (1986) 2.66
An Epstein-Barr virus transcript from a latently infected, growth-transformed B-cell line encodes a highly repetitive polypeptide. Proc Natl Acad Sci U S A (1986) 2.66
Suppression of in vitro Epstein-Barr virus infection. A new role for adult human T lymphocytes. J Exp Med (1977) 2.65
Presentation of viral antigen controlled by a gene in the major histocompatibility complex. Nature (1990) 2.65
Role for intracellular proteases in the processing and transport of class II HLA antigens. Proc Natl Acad Sci U S A (1988) 2.64
Structure of the peptidoglycan of bacterial spores: occurrence of the lactam of muramic acid. Proc Natl Acad Sci U S A (1969) 2.63
NK3-specific natural killer cells are selectively inhibited by Bw4-positive HLA alleles with isoleucine 80. J Exp Med (1994) 2.61