Published in Proc Natl Acad Sci U S A on March 01, 1974
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A comparative study of the early effects of phenobarbital and 3-methylcholanthrene on the synthesis and transport of ribonucleic acid in rat liver. Biochem J (1980) 0.82
Activation of 3':5'-cyclic AMP-dependent protein kinase and induction of ornithine decarboxylase as early events in induction of mixed-function oxygenases. Proc Natl Acad Sci U S A (1976) 0.81
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Specific inhibition of nuclear RNA polymerase II by alpha-amanitin. Science (1970) 6.39
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Isolation of nucleoli in a medium containing spermine and magnesium acetate. Exp Cell Res (1967) 1.28
Actinomycin D and the regulation of enzyme biosynthesis during development of Dictyostelium discoideum. J Mol Biol (1973) 1.23
The rapid acceleration of hepatic nuclear ribonucleic acid breakdown by actinomycin but not by ethionine. J Biol Chem (1968) 1.21
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Evidence for post-transcriptional stabilization of ribosomal precursor ribonucleic acid by phenobarbital. Mol Pharmacol (1972) 0.93
Disulfiram impairment of drug metabolism by rat liver microsomes. J Pharmacol Exp Ther (1969) 0.90
Tissue-specific stimulation of RNA synthesis by transformed estradiol-receptor complex. Biochem Biophys Res Commun (1972) 0.90
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Degradation of RNA in liver of rats treated with actinomycin D. Mol Pharmacol (1967) 0.81
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The effect of methylcholanthrene, phenobarbital and aflatoxin on RNA polymerase of rat liver. Adv Enzyme Regul (1967) 0.79
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Protein kinase activity of RNA polymerase I purified from a rat hepatoma: probable function of Mr 42,000 and 24,600 polypeptides. Proc Natl Acad Sci U S A (1981) 1.56
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Hypnotics and altered sleep-dream patterns. II. All-night EEG studies of chloral hydrate, flurazepam, and methaqualone. Arch Gen Psychiatry (1970) 1.50
Rebound insomnia: a new clinical syndrome. Science (1978) 1.38
Hypnotic drugs and their effectiveness. All-night EEG studies of insomniac subjects. Arch Gen Psychiatry (1970) 1.38
A heparin-sensitive nuclear protein kinase. Purification, properties, and increased activity in rat hepatoma relative to liver. J Biol Chem (1981) 1.37
Suppression of metallothionein gene expression in a rat hepatoma because of promoter-specific DNA methylation. J Biol Chem (2000) 1.36
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Sleep patterns of asthmaticchildren: all-night electroencephalographic studies. J Allergy (1970) 1.35
An alternative molecular mechanism of action of 5-fluorouracil, a potent anticancer drug. Biochem Pharmacol (1997) 1.34
Specific action of alpha-amanitin on mammalian RNA polymerase protein. Nature (1970) 1.32
Activation of purified hepatoma RNA polymerase I by homologous protein kinase NII. J Biol Chem (1981) 1.28
Altered characteristics of mammalian RNA polymerase following solubilization from nuclei. Biochem Biophys Res Commun (1968) 1.25
Zolpidem for persistent insomnia in SSRI-treated depressed patients. J Clin Psychiatry (1999) 1.25
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Simultaneous stimulation of slow-wave sleep and growth hormone secretion by gamma-hydroxybutyrate in normal young Men. J Clin Invest (1997) 1.21
Mechanism of early effect of hydrocortisone on the transcriptional process: stimulation of the activities of purified rat liver nucleolar RNA polymerases. Biochem Biophys Res Commun (1971) 1.20
Treatment of narcolepsy with gamma-hydroxybutyrate. A review of clinical and sleep laboratory findings. Sleep (1986) 1.20
Influenza virus infection induces metallothionein gene expression in the mouse liver and lung by overlapping but distinct molecular mechanisms. Mol Cell Biol (2001) 1.19
Specific inhibition of pre-ribosomal RNA processing in extracts from the lymphosarcoma cells treated with 5-fluorouracil. Cancer Res (1994) 1.19
Transcriptionally active RNA polymerases from Morris hepatomas and rat liver. Elucidation of the mechanism for the preferential increase in the tumour RNA polymerase I. Biochem J (1980) 1.16
Structurally and immunologically distinct poly(A) polymerases in rat liver. Occurrence of a tumor-type enzyme in normal liver. J Biol Chem (1984) 1.14
Effectiveness of hypnotic drugs with prolonged use: flurazepam and pentobarbital. Clin Pharmacol Ther (1975) 1.13
Effectiveness of temazepam with short-intermediate-, and long-term use: sleep laboratory evaluation. J Clin Pharmacol (1978) 1.11
Silencing of metallothionein-I gene in mouse lymphosarcoma cells by methylation. Oncogene (1999) 1.11
Polyriboadenylate polymerase solubilized from rat liver mitochondria. Biochem Biophys Res Commun (1972) 1.10
RNA polymerases from a rat hepatoma. Partial purification and comparison of properties with corresponding liver enzymes. Biochim Biophys Acta (1976) 1.10
Antibodies to distinct polypeptides of RNA polymerase I in sera from patients with rheumatic autoimmune disease. Proc Natl Acad Sci U S A (1982) 1.09
Chronic hypnotic-drug use. Ineffectiveness, drug-withdrawal insomnia, and dependence. JAMA (1974) 1.08
Poly(A) polymerase and poly(A)-specific mRNA binding protein are antigenically related. Nature (1979) 1.06
Nuclear poly(A) polymerase from rat liver and a hepatoma. Comparison of properties, molecular weights and amino acid compositions. Eur J Biochem (1976) 1.04
Role of poly(A) polymerase in the cleavage and polyadenylation of mRNA precursor. Mol Cell Biol (1989) 1.03
Phosphorylation of RNA polymerase I augments its interaction with autoantibodies of systemic lupus erythematosus patients. J Biol Chem (1984) 1.03
Evidence for extranucleolar control of RNA synthesis in the nucleolus. Biochem Biophys Res Commun (1970) 1.03
Presence of two RNA polymerase activities in liver nucleoli. Biochim Biophys Acta (1968) 1.03
Hypermethylation of metallothionein-I promoter and suppression of its induction in cell lines overexpressing the large subunit of Ku protein. J Biol Chem (1999) 1.03
A purified fraction containing RNA polymerase I that can accurately transcribe rat ribosomal RNA gene. Proc Natl Acad Sci U S A (1984) 1.03
Cigarette smoking associated with sleep difficulty. Science (1980) 1.02
Mitochondrial poly(A) polymerase from a poorly differentiated hepatoma: purification and characteristics. Biochemistry (1975) 1.02
Phosphorylation of nuclear poly(A) polymerase. Comparison of liver and hepatoma enzymes. J Biol Chem (1979) 1.02
Minimal rebound insomnia after treatment with 10-mg zolpidem. Clin Neuropharmacol (1997) 1.01
Effects of hypnotic drugs on memory. Life Sci (1979) 1.01
Drug dependency. Investigations of stimulants and depressants. Ann Intern Med (1969) 1.01
An enhancer element in the far upstream spacer region of rat ribosomal RNA gene. J Biol Chem (1987) 1.01
Stimulation of RNA polymerases I, II and III from rat liver by spermine, and specific inhibition of RNA polymerase I by higher spermine concentrations. Biochim Biophys Acta (1976) 0.99
Sleep in patients with Parkinson's disease and normal subjects prior to and following levodopa administration. Clin Pharmacol Ther (1971) 0.99
Specific inhibition of chromatin-associated poly(A) synthesis in vitro by cordycepin 5'-triphosphate. Nature (1977) 0.99
Enhancer 1 binding factor (E1BF), a Ku-related protein, is a growth-regulated RNA polymerase I transcription factor: association of a repressor activity with purified E1BF from serum-deprived cells. Proc Natl Acad Sci U S A (1994) 0.98
Regulation of nucleolar RNA metabolism by hydrocortisone. Eur J Biochem (1969) 0.98
Comparative efficacy and safety of nortriptyline and fluoxetine in the treatment of major depression: a clinical study. J Clin Psychiatry (1991) 0.97
Downregulation of constitutive and heavy metal-induced metallothionein-I expression by nuclear factor I. Gene Expr (2001) 0.97
A 37-base pair element in the far upstream spacer region can enhance transcription of rat rDNA in vitro and can bind to the core promoter-binding factor(s). J Biol Chem (1989) 0.96
Characterization of a factor that can prevent random transcription of cloned rDNA and its probable relationship to poly(ADP-ribose) polymerase. Nucleic Acids Res (1985) 0.96
DNA-dependent RNA polymerases I and II from kidney. Effect of polyamines on the in vitro transcription of DNA and chromatin. Biochemistry (1975) 0.95
The effects and effectiveness of gamma-hydroxybutyrate in patients with narcolepsy. J Clin Psychiatry (1985) 0.93
Metallothionein induction in response to restraint stress. Transcriptional control, adaptation to stress, and role of glucocorticoid. J Biol Chem (1998) 0.92
Heat shock selectively inhibits ribosomal RNA gene transcription and down-regulates E1BF/Ku in mouse lymphosarcoma cells. Biochem J (1996) 0.92
Composition of nucleoli isolated from mammalian cells. Natl Cancer Inst Monogr (1966) 0.91
Hypnotic efficacy of triazolam: sleep laboratory evaluation of intermediate-term effectiveness. J Clin Pharmacol (1976) 0.91
Propranolol in the treatment of narcolepsy. Ann Intern Med (1979) 0.91
Evidence for the nuclear origin of RNA polymerases identified in the cytosol: release of enzymes from the nuclei isolated in isotonic sucrose. Biochem Biophys Res Commun (1976) 0.91
Enhancer 1 binding factor, a Ku-related protein, is a positive regulator of RNA polymerase I transcription initiation. Proc Natl Acad Sci U S A (1994) 0.91
Purification and characterization of a novel factor which stimulates rat ribosomal gene transcription in vitro by interacting with enhancer and core promoter elements. Mol Cell Biol (1990) 0.90
Turnover of 45 S RNA of regenerating liver and Walker tumor. Cancer Res (1967) 0.90
The dual role of helix-loop--helix-zipper protein USF in ribosomal RNA gene transcription in vivo. Oncogene (1997) 0.90
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Lack of residual sedation following middle-of-the-night zaleplon administration in sleep maintenance insomnia. Clin Neuropharmacol (2000) 0.90
Transcriptional induction of metallothionein-I and -II genes in the livers of Cu,Zn-superoxide dismutase knockout mice. Biochem Biophys Res Commun (1999) 0.89
Accurate initiation of rat ribosomal RNA gene transcription using a fractionated nuclear extract from normal liver and a hepatoma. Proc Natl Acad Sci U S A (1985) 0.89
Characterization of the factor E1BF from a rat hepatoma that modulates ribosomal RNA gene transcription and its relationship to the human Ku autoantigen. Biochem Biophys Res Commun (1993) 0.88
Characterization of the 130-bp repeat enhancer element of the rat ribosomal gene: functional interaction with transcription factor E1BF. Gene (1993) 0.88
Alterations in DNA-dependent RNA polymerase I and II from rat liver by thioacetamide: preferential increase in the level of chromatin-associated nucleolar RNA polymerase IB. Biochemistry (1977) 0.88
Anti-RNA polymerase I antibodies in sera of MRL lpr/lpr and MRL +/+ autoimmune mice. Correlation of antibody production with delayed onset of lupus-like disease in MRL +/+ mice. J Exp Med (1985) 0.87
Novobiocin inhibits initiation of RNA polymerase II-directed transcription of the mouse metallothionein-I gene independent of its effect on DNA topoisomerase II. Nucleic Acids Res (1987) 0.87
Autoantibodies against RNA polymerase I in scleroderma and Sjögren's syndrome sera. Biochem Biophys Res Commun (1987) 0.87
Anti-protein kinase NII antibodies in rheumatic autoimmune diseases. J Biol Chem (1984) 0.87
Readaptation to the sleep laboratory in insomniac subjects. Psychophysiology (1975) 0.87
Regulation of ribosomal RNA gene transcription during retinoic acid-induced differentiation of mouse teratocarcinoma cells. Exp Cell Res (1997) 0.86
Morning amnestic effects of triazolam. Hillside J Clin Psychiatry (1986) 0.86
A subjective evaluation of a nasal dilator on sleep & snoring. Ear Nose Throat J (1994) 0.86
Transcription of eukaryotic ribosomal RNA gene. Mol Cell Biochem (1986) 0.86
Purification and characterization of a rat liver protein that recognizes CCAAT-homologous sequences of the metallothionein promoter and trans-activates this promoter. Arch Biochem Biophys (1997) 0.85
E1BF/Ku interacts physically and functionally with the core promoter binding factor CPBF and promotes the basal transcription of rat and human ribosomal RNA genes. Gene Expr (1995) 0.85
Comparison of cytosolic and nuclear poly(A) polymerases from rat liver and a hepatoma: structural and immunological properties and response to NI-type protein kinases. Biochemistry (1985) 0.85
Control of gene expression by lipophilic hormones. FASEB J (1993) 0.85
Functional role of zinc in poly(A) synthesis catalyzed by nuclear poly(A) polymerase. Eur J Biochem (1978) 0.85
Overexpression of the large subunit of the protein Ku suppresses metallothionein-I induction by heavy metals. Proc Natl Acad Sci U S A (1998) 0.84
Association of poly(A) polymerase with U1 RNA. J Biol Chem (1988) 0.84
Nocturnal oxygen desaturation in patients with sickle cell anemia. JAMA (1983) 0.84
Comparative effectiveness of nine hypnotic drugs: sleep laboratory studies. J Clin Pharmacol (1977) 0.83
Early androgen action in kidney of normal and androgen-insensitive (tfm/y) mice. Changes in RNA polymerase and chromatin template activities. Biochim Biophys Acta (1976) 0.83
Phosphorylation of purified glucocorticoid receptor from rat liver by an endogenous protein kinase. Biochem Biophys Res Commun (1984) 0.83
Effect of medroxyprogesterone acetate and testosterone on solubilized RNA polymerases and chromatin template activity in kidney from normal and androgen-insensitive (Tfm/Y) mice. Biochemistry (1978) 0.83
Poly(adenylic acid) synthesis in isolated rat liver mitochondria. Biochemistry (1976) 0.83
Glucocorticoid-induced stimulation of ribosomal gene transcription in rat hepatoma cells is mediated by modification of RNA polymerase I or an associated factor. Mol Endocrinol (1989) 0.83
Expression of purified mitochondrial poly(A)polymerase of hepatomas by an endogenous primer from liver.. Biochim Biophys Acta (1974) 0.83
Hydrolysis of poly (A) to adenine nucleotides by purified poly (A) polymerase. Proc Natl Acad Sci U S A (1978) 0.83