Published in Proc Natl Acad Sci U S A on March 01, 1974
A beta-D-galactoside binding protein from electric organ tissue of Electrophorus electricus. Proc Natl Acad Sci U S A (1975) 1.67
Role of cell membrane galactosyltransferase in concanavalin A agglutination of erythrocytes. Biochem J (1975) 1.06
Cell-surface glycosyltransferases in cultured fibroblasts: increased activity and release during serum stimulation of growth. Proc Natl Acad Sci U S A (1977) 0.98
Cell surface galactosyltransferase and lectin agglutination of thymus and spleen lymphocytes. Proc Natl Acad Sci U S A (1974) 0.92
Studies on the purification and properties of UDP-galactose glycoprotein galactosyltransferase from rat liver and serum. Biochem J (1976) 0.84
Cell surface modulation of gene expression in brain cells by down regulation of glucocorticoid receptors. Proc Natl Acad Sci U S A (1981) 0.83
Mechanism of human lymphocyte stimulation by concanavalin A: role of valence and surface binding sites. Proc Natl Acad Sci U S A (1976) 0.75
Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91
Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane. Biochemistry (1971) 66.90
The fluid mosaic model of the structure of cell membranes. Science (1972) 37.43
Intestinal epithelial cell surface membrane glycoprotein synthesis. I. An indicator of cellular differentiation. J Biol Chem (1973) 6.99
PROTEIN-CARBOHYDRATE INTERACTION. II. INHIBITION STUDIES ON THE INTERACTION OF CONCANAVALIN A WITH POLYSACCHARIDES. Biochemistry (1965) 6.56
Identification of Hemagglutinin of Jack Bean with Concanavalin A. J Bacteriol (1936) 6.29
A difference in the architecture of the surface membrane of normal and virally transformed cells. Proc Natl Acad Sci U S A (1969) 6.03
Identification of a tumor-specific determinant on neoplastic cell surfaces. Proc Natl Acad Sci U S A (1967) 5.63
The synthesis of complex carbohydrates by multiglycosyltransferase systems and their potential function in intercellular adhesion. Chem Phys Lipids (1970) 4.64
Binding of radioactively labelled concanavalin A and wheat germ agglutinin to normal and virus-transformed cells. Nat New Biol (1971) 2.88
Inside-out red cell membrane vesicles: preparation and purification. Science (1970) 2.61
Temperature-dependent mobility of concanavalin A sites on tumour cell surfaces. Nat New Biol (1973) 2.56
Ligand-induced redistribution of concanavalin A receptors on normal, trypsinized and transformed fibroblasts. Nat New Biol (1973) 2.18
Binding of 3 H-concanavalin A by normal and transformed cells. Nat New Biol (1971) 1.84
Intestinal epithelial cell surface membrane glycoprotein synthesis. II. Glycosyltransferases and endogenous acceptors of the undifferentiated cell surface membrane. J Biol Chem (1973) 1.78
Glycoprortein biosynthesis in small intestinal mucosa. I. A study of glycosyltransferases in microsomal subfractions. J Biol Chem (1971) 1.65
Embryonic and neoplastic cell surfaces: availability of receptors for concanavalin A and wheat germ agglutinin. Science (1971) 1.43
The use of concanavalin A for distinguishing IgM from IgG antibody-producing cells. J Immunol (1969) 1.30
Binding of ( 3 H)concanavalin A to normal and transformed cells. J Biol Chem (1973) 1.26
A specific metabolic activity on the surface membrane in malignant cell-transformation. Proc Natl Acad Sci U S A (1971) 1.19
Quantitation of N-acetyl-D-galactosamine-like sites on the surface membrane of normal and transformed mammalian cells. Biochim Biophys Acta (1971) 1.12
Concanavalin A agglutination of intestinal cells from the human fetus. Science (1972) 1.09
Surface changes in temperature-sensitive Simian virus 40-transformed cells. Proc Natl Acad Sci U S A (1973) 1.01
Glycosyltransferases in human blood.I. Galactosyltransferase in human serum and erythrocyte membranes. J Clin Invest (1972) 1.00
Specific selection of mitotically active intestinal cells by concanavalin A-derivatized fibers. J Cell Biol (1973) 0.91
Glutaraldehyde-insolubilized concanavalin A: an adsorbent for the specific isolation of polysaccharides and glycoproteins. Biochem J (1970) 0.79
Unravelling the pathogenesis of inflammatory bowel disease. Nature (2007) 18.52
Intestinal epithelial cell surface membrane glycoprotein synthesis. I. An indicator of cellular differentiation. J Biol Chem (1973) 6.99
Infliximab for the treatment of fistulas in patients with Crohn's disease. N Engl J Med (1999) 6.24
Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease. Infect Immun (2000) 5.65
Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome. Science (1999) 5.09
Epithelioid cell cultures from rat small intestine. Characterization by morphologic and immunologic criteria. J Cell Biol (1979) 4.86
Glucose transport in isolated brush border membrane from rat small intestine. J Biol Chem (1973) 4.75
Lipopolysaccharide activates distinct signaling pathways in intestinal epithelial cell lines expressing Toll-like receptors. J Immunol (2000) 4.12
Rat intestinal microvillus membranes. Purification and biochemical characterization. Biochem J (1968) 3.66
Heterozygous ATM mutations do not contribute to early onset of breast cancer. Nat Genet (1997) 3.66
Uptake and transport of macromolecules by the intestine. Possible role in clinical disorders. Gastroenterology (1974) 3.33
Impaired defense of intestinal mucosa in mice lacking intestinal trefoil factor. Science (1996) 3.32
The pathogenesis of arthritis associated with viral hepatitis. Complement-component studies. N Engl J Med (1971) 3.31
Germ-line BRCA1 mutations in Jewish and non-Jewish women with early-onset breast cancer. N Engl J Med (1996) 3.04
Evaluation of a serologic marker, CA19-9, in the diagnosis of pancreatic cancer. Ann Intern Med (1989) 3.02
Hypoxia-inducible factor 1-dependent induction of intestinal trefoil factor protects barrier function during hypoxia. J Exp Med (2001) 3.02
Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function. Gastroenterology (2007) 2.99
Infliximab in the treatment of severe, steroid-refractory ulcerative colitis: a pilot study. Inflamm Bowel Dis (2001) 2.80
Intestinal uptake of macromolecules: effect of oral immunization. Science (1972) 2.80
Abnormal structure and expression of p53 gene in human hepatocellular carcinoma. Proc Natl Acad Sci U S A (1990) 2.59
Trefoil peptides promote epithelial migration through a transforming growth factor beta-independent pathway. J Clin Invest (1994) 2.51
Small intestinal permeability to macromolecules. Transmission of horseradish peroxidase into mesenteric lymph and portal blood. Lab Invest (1971) 2.46
Biogenesis of intestinal plasma membrane: posttranslational route and cleavage of sucrase-isomaltase. Proc Natl Acad Sci U S A (1979) 2.45
Increased uptake of amino acids and 2-deoxy-D-glucose by virus-transformed cells in culture. Proc Natl Acad Sci U S A (1972) 2.41
Circulating immune complexes and complement activation in primary biliary cirrhosis. N Engl J Med (1978) 2.30
Increased expression of eukaryotic translation initiation factors eIF-4E and eIF-2 alpha in response to growth induction by c-myc. Proc Natl Acad Sci U S A (1993) 2.29
Reversal of oncogenesis by the expression of a major histocompatibility complex class I gene. Science (1985) 2.22
Small intestinal absorption of horseradish peroxidase. A cytochemical study. Lab Invest (1971) 2.20
Oral trefoil peptides protect against ethanol- and indomethacin-induced gastric injury in rats. Gastroenterology (1996) 2.17
Cytokine modulation of intestinal epithelial cell restitution: central role of transforming growth factor beta. Gastroenterology (1993) 2.13
The pathogenesis of arthritis associated with acute hepatitis-B surface antigen-positive hepatitis. Complement activation and characterization of circulating immune complexes. J Clin Invest (1975) 2.13
Glycoprotein composition of colonic mucosa. Specific alterations in ulcerative colitis. Gastroenterology (1984) 2.06
Oligosaccharide structures of human colonic mucin. J Biol Chem (1985) 2.06
Composition of human colonic mucin. Selective alteration in inflammatory bowel disease. J Clin Invest (1983) 2.03
Going the distance--the case for true colorectal-cancer screening. N Engl J Med (2000) 2.02
Expression of transforming growth factors alpha and beta in colonic mucosa in inflammatory bowel disease. Gastroenterology (1996) 2.01
Identification and characterization of rat intestinal trefoil factor: tissue- and cell-specific member of the trefoil protein family. Proc Natl Acad Sci U S A (1991) 2.01
Isovaleric acidemia: a new genetic defect of leucine metabolism. Proc Natl Acad Sci U S A (1966) 2.00
Differential contributions of BRCA1 and BRCA2 to early-onset breast cancer. N Engl J Med (1997) 1.97
Trefoil peptide protection of intestinal epithelial barrier function: cooperative interaction with mucin glycoprotein. Gastroenterology (1995) 1.93
Differential expression of transforming growth factors alpha and beta in rat intestinal epithelial cells. J Clin Invest (1989) 1.91
Intestinal epithelial cells both express and respond to interleukin 15. Gastroenterology (1996) 1.88
Fallibility of plasma-digoxin in differentiating toxic from non-toxic patients. Lancet (1971) 1.85
The trefoil peptide family. Annu Rev Physiol (1996) 1.83
Intestinal antibodies. N Engl J Med (1977) 1.82
Fractalkine is an epithelial and endothelial cell-derived chemoattractant for intraepithelial lymphocytes in the small intestinal mucosa. J Immunol (2000) 1.79
Intestinal epithelial cell surface membrane glycoprotein synthesis. II. Glycosyltransferases and endogenous acceptors of the undifferentiated cell surface membrane. J Biol Chem (1973) 1.78
Effects of growth factors on an intestinal epithelial cell line: transforming growth factor beta inhibits proliferation and stimulates differentiation. Biochem Biophys Res Commun (1987) 1.75
Decreased suppressor cell activity in inflammatory bowel disease. Clin Exp Immunol (1978) 1.75
Activation of natural killer T cells by alpha-galactosylceramide in the presence of CD1d provides protection against colitis in mice. Gastroenterology (2000) 1.75
Epithelial glycoprotein is a member of a family of epithelial cell surface antigens homologous to nidogen, a matrix adhesion protein. Proc Natl Acad Sci U S A (1990) 1.72
Very low density lipoproteins in intestinal lymph: origin, composition, and role in lipid transport in the fasting state. J Clin Invest (1969) 1.71
Enhanced colonic nitric oxide generation and nitric oxide synthase activity in ulcerative colitis and Crohn's disease. Gut (1995) 1.70
Adult human colonic subepithelial myofibroblasts express extracellular matrix proteins and cyclooxygenase-1 and -2. Am J Physiol (1997) 1.70
Serum antibodies to cow's milk proteins in ulcerative colitis and Crohn's disease. Gastroenterology (1987) 1.70
Expression of Fas ligand in liver metastases of human colonic adenocarcinomas. Proc Natl Acad Sci U S A (1997) 1.68
Normal serum ferritin concentrations in precirrhotic hemochromatosis. N Engl J Med (1976) 1.68
Circulating antibodies to bovine albumin in ulcerative colitis and Crohn's disease. Characterization of the antibody response. Gastroenterology (1976) 1.67
Macromolecular absorption. Mechanism of horseradish peroxidase uptake and transport in adult and neonatal rat intestine. J Cell Biol (1972) 1.66
Intestinal trefoil factor confers colonic epithelial resistance to apoptosis. Proc Natl Acad Sci U S A (2000) 1.66
Constant denaturant gel electrophoresis as a rapid screening technique for p53 mutations. Proc Natl Acad Sci U S A (1991) 1.65
Hepatitis-associated antigen and hepatoma in the U.S. Lancet (1971) 1.64
The reassociation of lipopolysaccharide, phospholipid, and transferase enzymes of the bacterial cell envelope. Isolation of binary and ternary complexes. J Biol Chem (1968) 1.63
Cell-mediated immunity in acute and chronic hepatitis. J Clin Invest (1975) 1.63
Expression of vascular adhesion molecules in inflammatory bowel disease. Gastroenterology (1992) 1.62
GALACTOSEMIA, A CONGENITAL DEFECT IN A NUCLEOTIDE TRANSFERASE: A PRELIMINARY REPORT. Proc Natl Acad Sci U S A (1956) 1.60
Alpha-fetoprotein in a patient with gastric carcinoma metastatic to the liver. N Engl J Med (1971) 1.59
Alteration in suppressor cell activity in chronic active hepatitis. Proc Natl Acad Sci U S A (1978) 1.57
Physician specialty and variations in the cost of treating patients with acute upper gastrointestinal bleeding. Gastroenterology (1997) 1.56
Fibroblast growth factors modulate intestinal epithelial cell growth and migration. Gastroenterology (1994) 1.55
Oligosaccharide structures of isolated human colonic mucin species. J Biol Chem (1985) 1.54
Peroxynitrite-induced rat colitis--a new model of colonic inflammation. Gastroenterology (1993) 1.53
Protein uptake by the intestine: evidence for absorption of intact macromolecules. Gastroenterology (1974) 1.53
Selective coactivation of estrogen-dependent transcription by CITED1 CBP/p300-binding protein. Genes Dev (2001) 1.53
Intestinal uptake of macromolecules. II. Effect of parenteral immunization. J Immunol (1973) 1.53
Transforming growth factor beta regulation of migration in wounded rat intestinal epithelial monolayers. Gastroenterology (1993) 1.51
The role of the Toll receptor pathway in susceptibility to inflammatory bowel diseases. Genes Immun (2007) 1.50
Lymphocyte cytotoxicity to autologous liver cells in chronic active hepatitis. Proc Natl Acad Sci U S A (1975) 1.49
Laminin receptor expression in rat intestine and liver during development and differentiation. Gastroenterology (1994) 1.49
Preparation and characterization of the lateral and basal plasma membranes of the rat intestinal epithelial cell. Biochem J (1972) 1.49
Intestinal uptake of macromolecules. III. Studies on the mechanism by which immunization interferes with antigen uptake. J Immunol (1975) 1.49
Fibronectin synthesis by epithelial crypt cells of rat small intestine. Proc Natl Acad Sci U S A (1978) 1.49
Immunodiagnosis of hepatitis B with high-affinity IgM monoclonal antibodies. Proc Natl Acad Sci U S A (1981) 1.48
Distinctions in chronic active hepatitis based on circulating hepatitis-associated antigen. Lancet (1970) 1.46
Migration of human intestinal lamina propria lymphocytes, macrophages and eosinophils following the loss of surface epithelial cells. Clin Exp Immunol (1997) 1.46
Human intestinal epithelial cells express functional cytokine receptors sharing the common gamma c chain of the interleukin 2 receptor. Proc Natl Acad Sci U S A (1995) 1.45
Bruton tyrosine kinase is tyrosine phosphorylated and activated in pre-B lymphocytes and receptor-ligated B cells. Proc Natl Acad Sci U S A (1994) 1.45
Absorption of medium and long chain triglycerides: factors influencing their hydrolysis and transport. J Clin Invest (1966) 1.44
Monoclonal antibodies to sucrase/isomaltase: probes for the study of postnatal development and biogenesis of the intestinal microvillus membrane. Proc Natl Acad Sci U S A (1980) 1.44
Establishment and characterization of a new human hepatocellular carcinoma cell line. In Vitro (1984) 1.43
The turnover of disaccharidases and brush border proteins in rat intestine. Biochim Biophys Acta (1971) 1.43
Normal human colonic subepithelial myofibroblasts enhance epithelial migration (restitution) via TGF-beta3. Am J Physiol (1999) 1.42
Tight clustering of human hepatitis B virus integration sites in hepatomas near a triple-stranded region. J Virol (1987) 1.42
Transcriptional activating activity of Smad4: roles of SMAD hetero-oligomerization and enhancement by an associating transactivator. Proc Natl Acad Sci U S A (1998) 1.41
Lipid composition of the isolated rat intestinal microvillus membrane. Biochem J (1968) 1.40