Published in J Biol Chem on June 10, 1973
Pyrimidine biosynthetic enzymes of Salmonella typhimurium, repressed specifically by growth in the presence of cytidine. J Bacteriol (1975) 1.65
Novel pyrazolo[3,4-d]pyrimidine nucleoside analog with broad-spectrum antiviral activity. Antimicrob Agents Chemother (1987) 1.02
A regulatory gene (use) affecting the expression of pyrA and certain other pyrimidine genes. J Bacteriol (1982) 1.01
Mechanism of formation, spectrum and reactivity of half-reduced eight-iron Clostridium pasteurianum ferredoxin in pulse-radiolysis studies and the non-co-operativity of the four-iron clusters. Biochem J (1979) 0.81
Hereditary orotic aciduria: evidence for a structural gene mutation. Proc Natl Acad Sci U S A (1974) 0.77
Absence of chromosome damage in human lymphocytes exposed to allopurinol and oxipurinol. Ann Rheum Dis (1976) 0.75
Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl) guanine. Proc Natl Acad Sci U S A (1977) 11.20
Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase. Proc Natl Acad Sci U S A (1986) 8.48
Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activity. Proc Natl Acad Sci U S A (1990) 6.85
A venue-based method for sampling hard-to-reach populations. Public Health Rep (2001) 6.43
Thymidine kinase from herpes simplex virus phosphorylates the new antiviral compound, 9-(2-hydroxyethoxymethyl)guanine. J Biol Chem (1978) 5.43
Inhibition of herpes simplex virus-induced DNA polymerase activity and viral DNA replication by 9-(2-hydroxyethoxymethyl)guanine and its triphosphate. J Virol (1979) 4.53
Mucoid Pseudomonas aeruginosa and cystic fibrosis: resistance of the mucoid from to carbenicillin, flucloxacillin and tobramycin and the isolation of mucoid variants in vitro. J Antimicrob Chemother (1978) 3.97
Age and visual search: expanding the useful field of view. J Opt Soc Am A (1988) 3.73
Alginate synthesis in mucoid Pseudomonas aeruginosa: a chromosomal locus involved in control. J Gen Microbiol (1980) 3.37
Ribavirin antagonizes the effect of azidothymidine on HIV replication. Science (1987) 2.51
Anaphylaxis in the United States: an investigation into its epidemiology. Arch Intern Med (2001) 2.48
Enzymatic assay for deoxyribonucleoside triphosphates using synthetic oligonucleotides as template primers. Anal Biochem (1989) 2.41
The anti-hepatitis B virus activities, cytotoxicities, and anabolic profiles of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine. Antimicrob Agents Chemother (1992) 2.38
Phosphorylation of acyclovir (acycloguanosine) monophosphate by GMP kinase. J Biol Chem (1980) 2.38
1592U89, a novel carbocyclic nucleoside analog with potent, selective anti-human immunodeficiency virus activity. Antimicrob Agents Chemother (1997) 2.31
The instability of mucoid Pseudomonas aeruginosa: fluctuation test and improved stability of the mucoid form in shaken culture. J Gen Microbiol (1979) 2.31
The 1985 Catalog of Mapped Genes and report of the Nomenclature Committee. Cytogenet Cell Genet (1985) 2.24
Trigeminal ganglion infection by thymidine kinase-negative mutants of herpes simplex virus. Science (1979) 2.23
Inhibition by acyclovir of cell growth and DNA synthesis of cells biochemically transformed with herpesvirus genetic information. Virology (1980) 2.18
A comparison of the specificities of xanthine oxidase and aldehyde oxidase. Arch Biochem Biophys (1972) 2.16
Isolation of a protein fraction from reticulocyte ribosomes required for de novo synthesis of hemoglobin. Arch Biochem Biophys (1968) 2.15
Revised pyocin typing method for Pseudomonas aeruginosa. J Clin Microbiol (1984) 2.15
Deoxycytidine kinase from calf thymus. Substrate and inhibitor specificity. J Biol Chem (1976) 2.14
Isolation of alginate-producing mutants of Pseudomonas fluorescens, Pseudomonas putida and Pseudomonas mendocina. J Gen Microbiol (1981) 2.04
Metabolic activation of the nucleoside analog 9-[( 2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine in human diploid fibroblasts infected with human cytomegalovirus. Proc Natl Acad Sci U S A (1985) 2.02
Human immunodeficiency virus type 1 integration protein: DNA sequence requirements for cleaving and joining reactions. J Virol (1992) 2.02
Human hypoxanthine phosphoribosyltransferase. I. Purification, properties, and specificity. J Biol Chem (1969) 2.01
Intercompartmental transport in the Golgi complex is a dissociative process: facile transfer of membrane protein between two Golgi populations. J Cell Biol (1984) 1.97
Enzymatic phosphorylation of acyclic nucleoside analogs and correlations with antiherpetic activities. Biochem Pharmacol (1981) 1.92
Effect of ultraviolet light on mengovirus: formation of uracil dimers, instability and degradation of capsid, and covalent linkage of protein to viral RNA. J Virol (1974) 1.78
A human cytomegalovirus mutant resistant to the nucleoside analog 9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine (BW B759U) induces reduced levels of BW B759U triphosphate. Proc Natl Acad Sci U S A (1986) 1.78
Guanine phosphoribosyltransferase from Escherichia coli, specificity and properties. Biochemistry (1972) 1.77
Altered thymidine-thymidylate kinases from strains of herpes simplex virus with modified drug sensitivities to acyclovir and (E)-5-(2-bromovinyl)-2'-deoxyuridine. Mol Pharmacol (1983) 1.75
Phosphorylation of acyclovir diphosphate by cellular enzymes. Biochem Pharmacol (1982) 1.75
A promoter associated with the neisserial repeat can be used to transcribe the uvrB gene from Neisseria gonorrhoeae. J Bacteriol (1995) 1.68
Inhibition of cellular alpha DNA polymerase and herpes simplex virus-induced DNA polymerases by the triphosphate of BW759U. Antimicrob Agents Chemother (1984) 1.67
Heterogeneity of antibiotic resistance in mucoid isolates of Pseudomonas aeruginosa obtained from cystic fibrosis patients: role of outer membrane proteins. Antimicrob Agents Chemother (1981) 1.66
Differential phosphorylation of (E)-5-(2-bromovinyl)-2'-deoxyuridine monophosphate by thymidylate kinases from herpes simplex viruses types 1 and 2 and varicella zoster virus. Mol Pharmacol (1982) 1.55
Allopurinol ribonucleoside as an antileishmanial agent. Biological effects, metabolism, and enzymatic phosphorylation. J Biol Chem (1979) 1.49
Retroviral-mediated gene therapy for the treatment of hepatocellular carcinoma: an innovative approach for cancer therapy. Proc Natl Acad Sci U S A (1991) 1.46
Differential effect of arabinofuranosylthymine of the replication of human herpesviruses. J Virol (1977) 1.44
Erdheim-Chester disease. Case report and review of the literature. Am J Med (1986) 1.44
Studies of an Epstein-Barr virus-induced DNA polymerase. Virology (1977) 1.43
Antibacterial activity and mechanism of action of 3'-azido-3'-deoxythymidine (BW A509U). Antimicrob Agents Chemother (1987) 1.41
Sunlight as disinfectant. Lancet (1988) 1.39
Prevention and therapy of serous otitis media by oral decongestant: a double-blind study in pediatric practice. Pediatrics (1978) 1.39
A comparison of the distribution and electron acceptor specificities of xanthine oxidase and aldehyde oxidase. Comp Biochem Physiol B (1974) 1.38
Adenosine kinase from rabbit liver. II. Substrate and inhibitor specificity. J Biol Chem (1979) 1.35
Sulfisoxazole as chemoprophylaxis for recurrent otitis media. A double-blind crossover study in pediatric practice. N Engl J Med (1974) 1.34
Cytoplasmic 5'-nucleotidase catalyzes acyclovir phosphorylation. J Biol Chem (1985) 1.33
Development and validation of adolescent-perceived microsystem scales: social support, daily hassles, and involvement. Am J Community Psychol (1995) 1.32
Effects of 3'-azido-3'-deoxythymidine on the deoxynucleotide triphosphate pools of cultured human cells. Biochem Biophys Res Commun (1988) 1.30
Cytokine induction by the immunomodulators imiquimod and S-27609. J Leukoc Biol (1995) 1.29
Imiquimod, a topical immune response modifier, induces migration of Langerhans cells. J Invest Dermatol (2000) 1.28
Brain cancer in petrochemical workers: a case series report. Am J Ind Med (1980) 1.27
Purine nucleoside synthesis, an efficient method employing nucleoside phosphorylases. Biochemistry (1981) 1.26
The Yale Geriatric Care Program: a model of care to prevent functional decline in hospitalized elderly patients. J Am Geriatr Soc (1993) 1.26
The crystal structure of Escherichia coli purine nucleoside phosphorylase: a comparison with the human enzyme reveals a conserved topology. Structure (1997) 1.25
6-Deoxyacyclovir: a xanthine oxidase-activated prodrug of acyclovir. Proc Natl Acad Sci U S A (1984) 1.25
Enhancement of the innate and cellular immune response in patients with genital warts treated with topical imiquimod cream 5%. Antiviral Res (1999) 1.24
Hemopericardium with use of oral anticoagulant therapy. JAMA (1969) 1.24
Clinical isolate of herpes simplex virus type 2 that induces a thymidine kinase with altered substrate specificity. Antimicrob Agents Chemother (1987) 1.24
Three-dimensional structure of thymidine phosphorylase from Escherichia coli at 2.8 A resolution. J Biol Chem (1990) 1.23
Modulation of TH1 and TH2 cytokine production with the immune response modifiers, R-848 and imiquimod. Cell Immunol (1999) 1.22
Vitamin B 12 biosynthesis. Enzyme studies on the formation of the alpha-glycosidic nucleotide precursor. J Biol Chem (1969) 1.22
Guanine and xanthine phosphoribosyltransfer activities of Lactobacillus casei and Escherichia coli. Their relationship to hypoxanthine and adenine phosphoribosyltransfer activities. J Biol Chem (1970) 1.21
EDIT10: a database interface for HGM10. Cytogenet Cell Genet (1989) 1.21
Aldehyde oxidase from rabbit liver: specificity toward purines and their analogs. Arch Biochem Biophys (1986) 1.20
Delusions and behavioral disturbances in cognitively impaired elderly persons. J Am Geriatr Soc (1992) 1.19
Xanthine oxidase from human liver: purification and characterization. Arch Biochem Biophys (1986) 1.17
Effects of somatosensory and parallel-fiber stimulation on neurons in dorsal cochlear nucleus. J Neurophysiol (1996) 1.17
Mapping and characterization of two mutations to antibiotic supersusceptibility in Pseudomonas aeruginosa. J Gen Microbiol (1987) 1.16
A randomized, controlled, molecular study of condylomata acuminata clearance during treatment with imiquimod. J Infect Dis (1998) 1.16
Disposition and pharmacodynamics of methamphetamine in pregnant sheep. JAMA (1991) 1.16
Cytokine induction in mice by the immunomodulator imiquimod. J Leukoc Biol (1994) 1.16
Stimulation of interferon and cytokine gene expression by imiquimod and stimulation by Sendai virus utilize similar signal transduction pathways. Mol Cell Biol (1995) 1.15
A second survey of graduates of a traditionally black college of medicine. Acad Med (1989) 1.14
Evaluation of a model of the cochlear neural membrane. I. Physiological measurement of membrane characteristics in response to intrameatal electrical stimulation. Hear Res (2000) 1.14
Posttherapy suppression of genital herpes simplex virus (HSV) recurrences and enhancement of HSV-specific T-cell memory by imiquimod in guinea pigs. Antimicrob Agents Chemother (1994) 1.14
Biochemical mechanisms of generation of bradykinin by endotoxin. J Infect Dis (1973) 1.12
Black student enrollment in US medical schools. JAMA (1989) 1.11
Hydroxylation of proline residues in collagen nascent chains. Arch Biochem Biophys (1970) 1.10
6-Methoxypurine arabinoside as a selective and potent inhibitor of varicella-zoster virus. Antimicrob Agents Chemother (1991) 1.09
Cellular requirements for cytokine production in response to the immunomodulators imiquimod and S-27609. J Interferon Cytokine Res (1995) 1.08
Detection of schistosome antigen in mummies. Lancet (1990) 1.08
Inhibition of human purine nucleoside phosphorylase. Studies with intact erythrocytes and the purified enzyme. J Biol Chem (1968) 1.07
Studies on dental aerobiology. I. Bacterial aerosols generated during dental procedures. J Dent Res (1969) 1.07
Varicella-zoster virus-induced DNA polymerase. J Gen Virol (1977) 1.07
Adenosine kinase from rabbit liver. I. Purification by affinity chromatography and properties. J Biol Chem (1979) 1.07
Immunomodulatory effects of Toll-like receptor-7 activation on chronic lymphocytic leukemia cells. Leukemia (2006) 1.07
Daily or weekly therapy with resiquimod (R-848) reduces genital recurrences in herpes simplex virus-infected guinea pigs during and after treatment. J Infect Dis (2001) 1.07
Studies on dental aerobiology. IV. Bacterial contamination of water delivered by dental units. J Dent Res (1972) 1.06
Somatic cell hybrid mapping panels. Exp Cell Res (1984) 1.06
Immunomodulating and antiviral activities of the imidazoquinoline S-28463. Antiviral Res (1995) 1.06