Published in J Pharmacol Exp Ther on August 01, 1979
Gentamicin, netilmicin, dibekacin, and amikacin nephrotoxicity and its relationship to tubular reabsorption in rabbits. Antimicrob Agents Chemother (1984) 1.15
Relationship between rat renal accumulation of gentamicin, tobramycin, and netilmicin and their nephrotoxicities. Antimicrob Agents Chemother (1985) 1.09
Correlation between renal membrane binding and nephrotoxicity of aminoglycosides. Antimicrob Agents Chemother (1987) 0.92
Renal ultrastructural and biochemical injuries induced by aminoglycosides. Environ Health Perspect (1984) 0.82
Influence of endotoxin on the intracortical accumulation kinetics of gentamicin in rats. Antimicrob Agents Chemother (1990) 0.81
Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med (2001) 22.32
Clinical response to aminoglycoside therapy: importance of the ratio of peak concentration to minimal inhibitory concentration. J Infect Dis (1987) 5.63
Development and progression of renal disease in Pima Indians with non-insulin-dependent diabetes mellitus. Diabetic Renal Disease Study Group. N Engl J Med (1996) 5.17
AHA Dietary Guidelines: revision 2000: A statement for healthcare professionals from the Nutrition Committee of the American Heart Association. Circulation (2000) 4.80
Muscle protein breakdown and the critical role of the ubiquitin-proteasome pathway in normal and disease states. J Nutr (1999) 3.45
Acyclovir prophylaxis of herpes-simplex-virus infections. N Engl J Med (1981) 3.19
Phase i/ii trial of the pharmacokinetics, safety, and antiretroviral activity of tenofovir disoproxil fumarate in human immunodeficiency virus-infected adults. Antimicrob Agents Chemother (2001) 2.84
A simple method of estimating progression of chronic renal failure. Lancet (1976) 2.72
Controlled comparison of amikacin and gentamicin. N Engl J Med (1977) 2.62
Association of aminoglycoside plasma levels with therapeutic outcome in gram-negative pneumonia. Am J Med (1984) 2.54
A method for estimating nitrogen intake of patients with chronic renal failure. Kidney Int (1985) 2.52
Double-blind comparison of the nephrotoxicity and auditory toxicity of gentamicin and tobramycin. N Engl J Med (1980) 2.51
The association of aminoglycoside plasma levels with mortality in patients with gram-negative bacteremia. J Infect Dis (1984) 2.44
The acidosis of chronic renal failure activates muscle proteolysis in rats by augmenting transcription of genes encoding proteins of the ATP-dependent ubiquitin-proteasome pathway. J Clin Invest (1996) 2.39
Isolation and characterisation of resistant Herpes simplex virus after acyclovir therapy. Lancet (1982) 2.28
Serum vancomycin concentrations: reappraisal of their clinical value. Clin Infect Dis (1994) 2.13
Identification of the lytic origin of DNA replication in human cytomegalovirus by a novel approach utilizing ganciclovir-induced chain termination. J Virol (1990) 2.10
Cephalothin plus an aminoglycoside is more nephrotoxic than methicillin plus an aminoglycoside. Lancet (1978) 2.10
Chloramphenicol: an enzymological microassay. Antimicrob Agents Chemother (1976) 2.10
Letter: Febrile reactions after methicillin. Lancet (1974) 2.09
Muscle wasting in insulinopenic rats results from activation of the ATP-dependent, ubiquitin-proteasome proteolytic pathway by a mechanism including gene transcription. J Clin Invest (1996) 2.07
Probenecid and zidovudine metabolism. Lancet (1989) 1.99
Glomerular filtration rate measurements in clinical trials. Modification of Diet in Renal Disease Study Group and the Diabetes Control and Complications Trial Research Group. J Am Soc Nephrol (1993) 1.99
The search for the uremic toxin: the case for metabolic acidosis. Wien Klin Wochenschr (1997) 1.95
Safety, pharmacokinetics, and antiretroviral activity of intravenous 9-[2-(R)-(Phosphonomethoxy)propyl]adenine, a novel anti-human immunodeficiency virus (HIV) therapy, in HIV-infected adults. Antimicrob Agents Chemother (1998) 1.94
AHA Dietary Guidelines: revision 2000: A statement for healthcare professionals from the Nutrition Committee of the American Heart Association. Stroke (2000) 1.90
Metabolic acidosis stimulates protein degradation in rat muscle by a glucocorticoid-dependent mechanism. J Clin Invest (1986) 1.78
Mechanisms for defects in muscle protein metabolism in rats with chronic uremia. Influence of metabolic acidosis. J Clin Invest (1987) 1.60
Two doses of PMPA protect newborn macaques against oral simian immunodeficiency virus infection. AIDS (1998) 1.58
Risk factors for nephrotoxicity in patients treated with aminoglycosides. Ann Intern Med (1984) 1.57
Pressor effect of naloxone in septic shock. Lancet (1981) 1.53
Risk factors for the development of auditory toxicity in patients receiving aminoglycosides. J Infect Dis (1984) 1.52
Zidovudine with probenecid: a warning. Lancet (1990) 1.51
Ubiquitin conjugation by the N-end rule pathway and mRNAs for its components increase in muscles of diabetic rats. J Clin Invest (1999) 1.45
Acidosis and glucocorticoids concomitantly increase ubiquitin and proteasome subunit mRNAs in rat muscle. Am J Physiol (1994) 1.44
Comparison of protein synthesis and degradation in incubated and perfused muscle. Biochem J (1983) 1.42
The losartan renal protection study--rationale, study design and baseline characteristics of RENAAL (Reduction of Endpoints in NIDDM with the Angiotensin II Antagonist Losartan). J Renin Angiotensin Aldosterone Syst (2000) 1.35
Relationship between aminoglycoside-induced nephrotoxicity and auditory toxicity. Antimicrob Agents Chemother (1979) 1.33
Clinical pharmacokinetics of cidofovir in human immunodeficiency virus-infected patients. Antimicrob Agents Chemother (1995) 1.32
Progression of overt nephropathy in non-insulin-dependent diabetes. Kidney Int (1995) 1.30
Pharmacokinetics, safety and bioavailability of HPMPC (cidofovir) in human immunodeficiency virus-infected subjects. Antiviral Res (1996) 1.29
Intracellular zidovudine (ZDV) and ZDV phosphates as measured by a validated combined high-pressure liquid chromatography-radioimmunoassay procedure. Antimicrob Agents Chemother (1992) 1.29
Disposition of intravenous radioactive acyclovir. Clin Pharmacol Ther (1981) 1.27
Early detection and the course of glomerular injury in patients with sickle cell anemia. Kidney Int (1996) 1.25
Glomerular function in Pima Indians with noninsulin-dependent diabetes mellitus of recent onset. J Clin Invest (1991) 1.25
Systemic response to thermal injury in rats. Accelerated protein degradation and altered glucose utilization in muscle. J Clin Invest (1984) 1.25
Interactions between L-arginine and L-glutamine change endothelial NO production. An effect independent of NO synthase substrate availability. J Clin Invest (1995) 1.25
Enac degradation in A6 cells by the ubiquitin-proteosome proteolytic pathway. J Biol Chem (2001) 1.25
The impact of a drug information sheet on the understanding and attitude of patients about drugs. JAMA (1986) 1.24
Angiotensin II induces skeletal muscle wasting through enhanced protein degradation and down-regulates autocrine insulin-like growth factor I. Endocrinology (2001) 1.24
Creatinine metabolism in chronic renal failure. Clin Sci (Lond) (1980) 1.23
Concentrations of gentamicin and amikacin in human kidneys. Antimicrob Agents Chemother (1976) 1.22
Regulation of epithelial sodium channels by the ubiquitin-proteasome proteolytic pathway. Am J Physiol Renal Physiol (2006) 1.20
Role of Nedd4-2 and polyubiquitination in epithelial sodium channel degradation in untransfected renal A6 cells expressing endogenous ENaC subunits. Am J Physiol Renal Physiol (2005) 1.18
Acyclovir prophylaxis against herpes simplex virus infection in patients with leukemia. A randomized, double-blind, placebo-controlled study. Ann Intern Med (1983) 1.18
Oral antibiotic treatment of right-sided staphylococcal endocarditis in injection drug users: prospective randomized comparison with parenteral therapy. Am J Med (1996) 1.18
Catabolism in uremia: the impact of metabolic acidosis. J Am Soc Nephrol (1998) 1.16
Multicenter collaborative trial of intravenous acyclovir for treatment of mucocutaneous herpes simplex virus infection in the immunocompromised host. Am J Med (1982) 1.16
Acute iron poisoning. A review. Am J Dis Child (1980) 1.14
Response of the kidney to furosemide. I. Effects of salt intake and renal compensation. J Lab Clin Med (1983) 1.14
Aminoglycoside inhibition of a renal phosphatidylinositol phospholipase C. J Pharmacol Exp Ther (1982) 1.14
The effect of a keto acid-amino acid supplement to a restricted diet on the progression of chronic renal failure. N Engl J Med (1984) 1.14
Dextran sulfate is poorly absorbed after oral administration. Ann Intern Med (1989) 1.13
Glucocorticoids induce proteasome C3 subunit expression in L6 muscle cells by opposing the suppression of its transcription by NF-kappa B. J Biol Chem (2000) 1.13
Anti-human immunodeficiency virus (HIV) activity, safety, and pharmacokinetics of adefovir dipivoxil (9-[2-(bis-pivaloyloxymethyl)-phosphonylmethoxyethyl]adenine) in HIV-infected patients. J Infect Dis (1997) 1.12
Muscle protein turnover and glucose uptake in acutely uremic rats. Effects of insulin and the duration of renal insufficiency. J Clin Invest (1983) 1.11
Selectivity of the insulin-like actions of vanadate on glucose and protein metabolism in skeletal muscle. Biochem J (1985) 1.10
Nephrotoxicity induced by gentamicin and amikacin. Johns Hopkins Med J (1978) 1.10
A double-blind controlled trial of anti-Pseudomonas chemotherapy of acute respiratory exacerbations in patients with cystic fibrosis. J Pediatr (1981) 1.09
Disorders of body fluids, sodium and potassium in chronic renal failure. Am J Med (1982) 1.09
Renal disease in pregnancy. Med Clin North Am (1977) 1.08
Abnormalities in protein synthesis and degradation induced by extracellular pH in BC3H1 myocytes. Am J Physiol (1991) 1.08
Pharmacokinetics and tolerance of acyclovir, a new anti-herpesvirus agent, in humans. Antimicrob Agents Chemother (1982) 1.07
Chaperone use by residents during pelvic, breast, testicular, and rectal exams. J Gen Intern Med (2000) 1.07
Effects of probenecid on the pharmacokinetics and elimination of acyclovir in humans. Antimicrob Agents Chemother (1982) 1.07
Glucocorticoids and acidosis stimulate protein and amino acid catabolism in vivo. Kidney Int (1996) 1.06
Nitrogen sparing induced by leucine compared with that induced by its keto analogue, alpha-ketoisocaproate, in fasting obese man. J Clin Invest (1981) 1.03
Oral chloramphenicol therapy. J Pediatr (1981) 1.03
Effect of large oral doses of ascorbic acid on uric acid excretion by normal subjects. Clin Pharmacol Ther (1981) 1.02
Specificity of the effects of leucine and its metabolites on protein degradation in skeletal muscle. Biochem J (1984) 1.02
Cefotaxime compared with nafcillin plus tobramycin for serious bacterial infections. A randomized, double-blind trial. Ann Intern Med (1984) 1.02
Effects of high doses of glucocorticoids on free amino acids, ribosomes and protein turnover in human muscle. Eur J Clin Invest (2002) 1.01
Revision 2000: a statement for healthcare professionals from the Nutrition Committee of the American Heart Association. J Nutr (2001) 1.01
Protein degradation and increased mRNAs encoding proteins of the ubiquitin-proteasome proteolytic pathway in BC3H1 myocytes require an interaction between glucocorticoids and acidification. Proc Natl Acad Sci U S A (1996) 1.01
Race and the risk of peritonitis: an analysis of factors associated with the initial episode. Kidney Int (1994) 1.00
Effect of polyamines on a ribonuclease which hydrolyzes ribonucleic acid at uridylic acid residues. J Biol Chem (1973) 1.00
Identification of NaK-ATPase inhibitors in human plasma as nonesterified fatty acids and lysophospholipids. J Biol Chem (1986) 0.99
Double-blind comparison of cefamandole and penicillin in pneumococcal pneumonia. Antimicrob Agents Chemother (1978) 0.99
Netilmicin and gentamicin multidose kinetics in normal subjects. Clin Pharmacol Ther (1983) 0.99
Chloramphenicol and the neonate--1979 view. Clin Perinatol (1979) 0.98
Letter: Overdoses of chloramphenicol. JAMA (1975) 0.98
Mitochondrial protein synthesis: inhibition by emetine hydrochloride. Mol Pharmacol (1971) 0.97
Safety and tolerability of fluoroquinolones. Drugs (1993) 0.96
The pharmacokinetics of amikacin in children. J Pediatr (1977) 0.96
Specific defects in insulin-mediated muscle metabolism in acute uremia. Kidney Int (1985) 0.95
Characterization of digitalis-like factors in human plasma. Interactions with NaK-ATPase and cross-reactivity with cardiac glycoside-specific antibodies. J Biol Chem (1985) 0.94
Molecular mechanisms activating muscle protein degradation in chronic kidney disease and other catabolic conditions. Eur J Clin Invest (2005) 0.93
Adult cystinosis--a benign disorder. Am J Med (1966) 0.93
Studies of risk factors for aminoglycoside nephrotoxicity. Am J Kidney Dis (1986) 0.93