Published in Biochem Biophys Res Commun on August 19, 1974
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Comparison between macrophage activation and enhancement of nonspecific resistance to tumors by mycobacterial immunoadjuvants. Proc Natl Acad Sci U S A (1975) 1.91
Stimulation of the reticuloendothelial system of mice by muramyl dipeptide. Infect Immun (1979) 1.84
Granuloma formation by synthetic bacterial cell wall fragment: muramyl dipeptide. Infect Immun (1978) 1.80
Activation of macrophages for enhanced release of superoxide anion and greater killing of Candida albicans by injection of muramyl dipeptide. J Exp Med (1980) 1.79
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Enhancement of certain biological activities of muramyl dipeptide derivatives after conjugation to a multi-poly(DL-alanine)--poly(L-lysine) carrier. Proc Natl Acad Sci U S A (1979) 1.48
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Mitogenic effects of bacterial cell walls, their fragments, and related synthetic compounds on thymocytes and splenocytes of guinea pigs. Infect Immun (1979) 1.36
Eradication of spontaneous metastases and activation of alveolar macrophages by intravenous injection of liposomes containing muramyl dipeptide. Proc Natl Acad Sci U S A (1981) 1.34
Protective effect of muramyl dipeptide analogs against infections of Pseudomonas aeruginosa or Candida albicans in mice. Infect Immun (1981) 1.33
Immunization against malaria with antigen from Plasmodium falciparum cultivated in vitro. Proc Natl Acad Sci U S A (1978) 1.27
Adjuvant activity of synthetic N-acetylmuramyl peptides in rats. Infect Immun (1977) 1.27
Enhancement of host resistance against Trypanosoma cruzi infection by the immunoregulatory agent muramyl dipeptide. Infect Immun (1979) 1.26
Successful immunization with a totally synthetic diphtheria vaccine. Proc Natl Acad Sci U S A (1982) 1.26
Central pyrogenic activity of muramyl dipeptide. J Exp Med (1980) 1.26
Chitin, chitinases and chitinase-like proteins in allergic inflammation and tissue remodeling. Yonsei Med J (2009) 1.26
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Effect of L18-MDP(Ala), a synthetic derivative of muramyl dipeptide, on nonspecific resistance of mice to microbial infections. Infect Immun (1982) 1.22
Immunostimulant activities of a lipophilic muramyl dipeptide derivative and of desmuramyl peptidolipid analogs. Infect Immun (1980) 1.21
Tumor necrosis factor amplifies measles virus-mediated Ia induction on astrocytes. Proc Natl Acad Sci U S A (1987) 1.18
Effects of muramyl dipeptide treatment on resistance to infection with Toxoplasma gondii in mice. Infect Immun (1981) 1.17
Adjuvant polyarthritis. V. Induction by N-acetylmuramyl-L-alanyl-D-isoglutamine, the smallest peptide subunit of bacterial peptidoglycan. J Exp Med (1981) 1.16
Adjuvant activity of synthetic 6-O-"mycoloyl"-N-acetylmuramyl-L-alanyl-D-isoglutamine and related compounds. Infect Immun (1978) 1.15
Cord factor and peptidoglycan recapitulate the Th17-promoting adjuvant activity of mycobacteria through mincle/CARD9 signaling and the inflammasome. J Immunol (2013) 1.15
NOD2 triggers an interleukin-32-dependent human dendritic cell program in leprosy. Nat Med (2012) 1.14
Epithelioid granuloma formation by a synthetic bacterial cell wall component, muramyl dipeptide (MDP). Am J Pathol (1980) 1.14
A structure-activity relationship for induction of meningeal inflammation by muramyl peptides. J Clin Invest (1993) 1.13
Stimulation of nonspecific resistance to infection induced by 6-O-acyl muramyl dipeptide analogs in mice. Infect Immun (1981) 1.12
Stimulating effect of MDP and its adjuvant-active analogues on guinea pig fibroblasts for the production of thymocyte-activating factor. J Exp Med (1983) 1.11
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Arthritis-inducing ability of a synthetic adjuvant, N-acetylmuramyl peptides, and bacterial disaccharide peptides related to different oil vehicles and their composition. Infect Immun (1980) 1.09
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Adjuvant activities of quinonyl-N-acetyl muramyl dipeptides in mice and guinea pigs. Infect Immun (1981) 1.08
N-acetyl muramyl dipeptide stimulation of bone resorption in tissue culture. Infect Immun (1982) 1.07
Granuloma formation by muramyl dipeptide associated with branched fatty acids, a structure probably essential for tubercle formation by Mycobacterium tuberculosis. Infect Immun (1985) 1.03
Stimulation of chemiluminescence and resistance against aerogenic influenza virus infection by synthetic muramyl dipeptide combined with trehalose dimycolate. Infect Immun (1984) 1.02
Relationship of anti-tuberculous protection to lung granuloma produced by intravenous injection of synthetic 6-O-mycoloyl-N-acetylmuramyl-L-alanyl-D-isoglutamine with or without specific antigens. Immunology (1980) 1.01
Adjuvant activity of N-acetyl muramyl dipeptides for the induction of delayed-type hypersensitivity to azobenzenearsonate-N-acetyl-L-tyrosine in guinea pigs. Infect Immun (1980) 1.01
Failure of synthetic muramyl dipeptide to increase antibacterial resistance. Infect Immun (1980) 1.00
Experimental production of pulmonary granulomas. I. Immune granulomas induced by chemically modified cell walls and their constituents. Br J Exp Pathol (1981) 1.00
Muramyl peptides. Variation of somnogenic activity with structure. J Exp Med (1984) 0.99
Induction of interleukin 1 secretion by adjuvant-active peptidoglycans. Infect Immun (1983) 0.99
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Adjuvanticity (immunity-inducing property) of cord factor in mice and rats. Infect Immun (1977) 0.98
Stimulation of nonspecific resistance to infection induced by muramyl dipeptide analogs substituted in the gamma-carboxyl group and evaluation of N alpha-muramyl dipeptide-N epsilon-stearoyllysine. Infect Immun (1983) 0.97
Immuno-stimulation by a ribosomal vaccine associated with a bacterial cell wall adjuvant in humans. Infect Immun (1978) 0.97
Modulation of adaptive immunity by different adjuvant-antigen combinations in mice lacking Nod2. Vaccine (2008) 0.96
Agonists of Toll-like receptors 3, 4, 7, and 9 are candidates for use as adjuvants in an outer membrane vaccine against Neisseria meningitidis serogroup B. Infect Immun (2007) 0.96
Effects of treatment with muramyl dipeptide and certain of its analogs on resistance to Listeria monocytogenes in mice. Infect Immun (1980) 0.96
Stimulation of macrophage protease secretion via liposomal delivery of muramyl dipeptide derivatives to intracellular sites. Immunology (1984) 0.95
Innate immunity: ignored for decades, but not forgotten. J Invest Dermatol (2011) 0.95
Two adjuvant-active muramyl dipeptide analogs induce differential production of lymphocyte-activating factor and a factor causing distress in guinea pigs. Infect Immun (1984) 0.95
Bordetella pertussis tracheal cytotoxin and other muramyl peptides: distinct structure-activity relationships for respiratory epithelial cytopathology. Proc Natl Acad Sci U S A (1993) 0.95
Arthritogenic activity of a synthetic immunoadjuvant, muramyl dipeptide. Infect Immun (1982) 0.95
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Novel human polysaccharide adjuvants with dual Th1 and Th2 potentiating activity. Vaccine (2006) 0.93
Effect of oral administration of lysozyme or digested bacterial cell walls on immunostimulation in guinea pigs. Infect Immun (1981) 0.93
Enhancement by murabutide of the immune response to natural and synthetic hepatitis B surface antigens. Infect Immun (1984) 0.93
Immunological castration of male mice by a totally synthetic vaccine administered in saline. Proc Natl Acad Sci U S A (1982) 0.92
Retracted Genetic determination of the meso-diaminopimelate biosynthetic pathway of mycobacteria. J Bacteriol (1994) 0.91
Modulation of myelopoiesis in vivo by synthetic adjuvant-active muramyl peptides: induction of colony-stimulating activity and stimulation of stem cell proliferation. Infect Immun (1983) 0.91
Synergistic effect of glucantime and a liposome-encapsulated muramyl dipeptide analog in therapy of experimental visceral leishmaniasis. Infect Immun (1985) 0.91
Adjuvant activity of 6-O-mycoloyl derivatives of N-acetylmuramyl-L-seryl-D-isoglutamine and related compounds in mice and guinea pigs. Infect Immun (1979) 0.91
Comparison of muramyl dipeptide, trehalose dimycolate, and dimethyl dioctadecyl ammonium bromide as adjuvants in Brucella abortus 45/20 vaccines. Infect Immun (1980) 0.91
Immunotherapy of experimental cancer with a mixture of synthetic muramyl dipeptide and trehalose dimycolate. Infect Immun (1981) 0.91
Role of Staphylococcus aureus cell wall antigens in the stimulation of delayed hypersensitivity after staphylococcal infection. Infect Immun (1978) 0.90
Influence of a synthetic adjuvant (MDP) on qualitative and quantitative changes of serum globulins. Immunology (1978) 0.90
Efficient genetically controlled formation of antibody to a synthetic antigen [poly(LTyr, LGlu)-poly(DLAla)- -poly(LLys)] covalently bound to a synthetic adjuvant (N-acetylmuramyl-L-alanyl-D-isoglutamine). Proc Natl Acad Sci U S A (1980) 0.90
Advances in aluminum hydroxide-based adjuvant research and its mechanism. Hum Vaccin Immunother (2015) 0.89
NOD-like receptor activation by outer membrane vesicles from Vibrio cholerae non-O1 non-O139 strains is modulated by the quorum-sensing regulator HapR. Infect Immun (2011) 0.89
Detection of muramic acid in a carbohydrate fraction of human spleen. Infect Immun (1995) 0.89
Adjuvant activity of purified peptidoglycan of Listeria monocytogenes in mice and guinea pigs. Infect Immun (1982) 0.88
Where asthma and hypersensitivity pneumonitis meet and differ: noneosinophilic severe asthma. Am J Pathol (2008) 0.88
Synthesis and biological assays of a peptide from a tuberculin-active protein. Infect Immun (1980) 0.87
Effects of natural or synthetic microbial adjuvants on induction of autoimmune thyroiditis. Infect Immun (1985) 0.87
The macrophage response to bacteria. Modulation of macrophage functional activity by peptidoglycan from Moraxella (Branhamella) catarrhalis. Clin Exp Immunol (1992) 0.87
Immunization of cattle with a variant-specific surface antigen of Trypanosoma brucei: influence of different adjuvants. Infect Immun (1982) 0.86
Synergistic effect of polyriboinosinic acid:polyribocytidylic acid and either bacterial peptidoglycans or synthetic N-acetylmuramyl peptides on production of adjuvant-induced arthritis in rats. Infect Immun (1979) 0.86
Adjuvant effect of a peptidoglycan attached covalently to a synthetic antigen provoking anti-phage antibodies. Immunology (1978) 0.86
Enhancement of nonspecific immunity to Klebsiella pneumoniae infection by a synthetic immunoadjuvant (N-acetylmuramyl-L-alanyl-D-isoglutamine) and several analogs. Proc Natl Acad Sci U S A (1977) 3.31
Insertion of long term central venous catheters: time for a new look. BMJ (1995) 2.92
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The mycobacterial cell wall. Pure Appl Chem (1971) 1.90
Adjuvant activity of monomeric bacterial cell wall peptidoglycans. Biochem Biophys Res Commun (1974) 1.82
Occurrence of D-alanyl-(D)-meso-diaminopimelic acid and meso-diaminopimelyl-meso-diaminopimelic acid interpeptide linkages in the peptidoglycan of Mycobacteria. Biochemistry (1974) 1.79
Immune response to sheep red blood cells in mice pretreated with mycobacterial fractions. Infect Immun (1971) 1.79
Cellular reaction in the footpad and draining lymph nodes of mice induced by mycobacterial fractions and BCG bacilli. Infect Immun (1971) 1.77
Biological activity of a new synthetic muramyl peptide adjuvant devoid of pyrogenicity. Infect Immun (1982) 1.73
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Self-expanding metal stents for the palliation of dysphagia due to inoperable oesophageal carcinoma. Br J Surg (1995) 1.66
Fate of the synthetic immunoadjuvant, muramyl dipeptide (14C-labelled) in the mouse. Int J Immunopharmacol (1979) 1.65
Total synthesis and adjuvant activity of bacterial peptidoglycan derivatives. Biochem Biophys Res Commun (1975) 1.64
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Cell walls of Mycobacteria and related organisms; chemistry and immunostimulant properties. Mol Cell Biochem (1975) 1.55
Synthetic immunostimulants derived from the bacterial cell wall. J Med Chem (1980) 1.54
Isolation of mitogenic and adjuvant active fractions from various species of Nocardiae. Infect Immun (1975) 1.54
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Cord factor and related trehalose esters. Chem Phys Lipids (1976) 1.52
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Muramyl peptides: immunomodulators, sleep factors, and vitamins. Med Res Rev (1984) 1.40
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Apparent deficiency of hexosaminidase A in healthy members of a family with Tay-Sachs disease. Am J Hum Genet (1973) 1.35
A human T-independent B lymphocyte mitogen extracted from Nocardia opaca. J Immunol (1976) 1.33
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Immunotherapy of Cancer with Nonliving BCG and Fractions Derived from Mycobacteria: Role of Cord Factor (Trehalose-6, 6'-Dimycolate) in Tumor Regression. Infect Immun (1974) 1.31
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Stimulation of thymocyte mitogenic protein secretion and of cytostatic activity of mouse peritoneal macrophages by trehalose dimycolate and muramyldipeptide. Eur J Immunol (1980) 1.27
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