Published in Life Sci on December 15, 1974
Vasoactive intestinal polypeptide in brain: localization in and release from isolated nerve terminals. Proc Natl Acad Sci U S A (1977) 1.16
Substance P enhances cholinergic receptor desensitization in a clonal nerve cell line. Proc Natl Acad Sci U S A (1980) 1.09
Substance P and Renshaw cells: a new concept of inhibitory synaptic interactions. J Physiol (1977) 0.98
Substance P in the bovine retina: localization, identification, release, uptake and receptor analysis. J Physiol (1984) 0.76
Es kann die Spur von unseren Erdetagen--on pharmacologists and pharmacology. Naunyn Schmiedebergs Arch Pharmacol (2009) 0.75
The isolation of a new hypotensive peptide, neurotensin, from bovine hypothalami. J Biol Chem (1973) 3.83
Isolation of a sialogogic peptide from bovine hypothalamic tissue and its characterization as substance P. J Biol Chem (1970) 2.49
Enkephalin inhibits release of substance P from sensory neurons in culture and decreases action potential duration. Proc Natl Acad Sci U S A (1979) 2.47
CP-96,345, a substance P antagonist, inhibits rat intestinal responses to Clostridium difficile toxin A but not cholera toxin. Proc Natl Acad Sci U S A (1994) 2.22
Intrathecal morphine inhibits substance P release from mammalian spinal cord in vivo. Nature (1980) 2.08
Amino-acid sequence of substance P. Nat New Biol (1971) 1.96
Multiple calcium channels mediate neurotransmitter release from peripheral neurons. Proc Natl Acad Sci U S A (1986) 1.85
Characterization of radioimmunoassayable neurotensin in the rat. Its differential distribution in the central nervous system, small intestine, and stomach. J Biol Chem (1976) 1.79
Increased substance P responses in dorsal root ganglia and intestinal macrophages during Clostridium difficile toxin A enteritis in rats. Proc Natl Acad Sci U S A (1997) 1.70
Substance P as a transmitter candidate. Annu Rev Neurosci (1980) 1.64
The amino acid sequence of a hypothalamic peptide, neurotensin. J Biol Chem (1975) 1.49
Ultrastructural localization of substance P in neurons of rat spinal cord. Brain Res (1977) 1.34
Intrathecal capsaicin depletes substance P in the rat spinal cord and produces prolonged thermal analgesia. Science (1979) 1.33
Immunoreactive substance P in sympathetic ganglia: distribution and sensitivity towards capsaicin. Neuroscience (1981) 1.32
Regional distribution of substance P in the brain of the rat. Brain Res (1976) 1.23
Substance P receptor expression in intestinal epithelium in clostridium difficile toxin A enteritis in rats. Am J Physiol (1998) 1.21
The origin, distribution and synaptic relationships of substance P axons in rat spinal cord. J Comp Neurol (1979) 1.21
Neurotensin stimulates exocytotic histamine secretion from rat mast cells and elevates plasma histamine levels. J Physiol (1982) 1.19
A substance P (neurokinin-1) receptor mutant carboxyl-terminally truncated to resemble a naturally occurring receptor isoform displays enhanced responsiveness and resistance to desensitization. Proc Natl Acad Sci U S A (1997) 1.18
Differential effects of capsaicin on the content of somatostatin, substance P, and neurotensin in the nervous system of the rat. Naunyn Schmiedebergs Arch Pharmacol (1981) 1.17
Radioimmunoassay for neurotensin, a hypothalamic peptide. J Biol Chem (1976) 1.15
Isolation of human intestinal neurotensin. J Biol Chem (1980) 1.14
Biochemical characterization of two different forms of the substance P receptor in rat submaxillary gland. J Neurochem (1993) 1.13
A substance P antagonist, RP-67,580, ameliorates a mouse meningoencephalitic response to Trypanosoma brucei brucei. Proc Natl Acad Sci U S A (1997) 1.10
Immunohistochemical localization of neurotensin in endocrine cells of the gut. Cell Tissue Res (1977) 1.09
Isolation of a tridecapeptide from bovine intestinal tissue and its partial characterization as neurotensin. J Biol Chem (1976) 1.09
Effect of capsaicin pretreatment on capsaicin-evoked release of immunoreactive somatostatin and substance P from primary sensory neurons. Naunyn Schmiedebergs Arch Pharmacol (1981) 1.03
Synthesis of substance P. Nat New Biol (1971) 1.02
Somatostatin and substance P inhibit catecholamine secretion from isolated cells of guinea-pig adrenal medulla. Neuroscience (1981) 1.01
Electron microscopic localization of substance P and enkephalin in axon terminals related to dendrites of catecholaminergic neurons. Brain Res (1979) 1.00
Identification of the motoneuron-depolarizing peptide in bovine dorsal root as hypothalamic substance P. Brain Res (1974) 0.99
Inhibition of flank-marking behavior in golden hamsters by microinjection of a vasopressin antagonist into the hypothalamus. Neurosci Lett (1985) 0.98
The amino acid sequence of radioimmunoassayable neurotensin from bovine intestine. J Biol Chem (1978) 0.98
Inhibition of kinesin synthesis in vivo inhibits the rapid transport of representative proteins for three transport vesicle classes into the axon. J Neurochem (1995) 0.96
Stimulation of salivary secretion by a factor extracted from hypothalamic tissue. Endocrinology (1967) 0.96
On the origin of substance P and glutamic acid decarboxylase (GAD) in the substantia nigra. Brain Res (1977) 0.96
The synthesis of neurotensin. J Biol Chem (1975) 0.95
Neurotensin stimulates [3H]oleic acid translocation across rat small intestine. Am J Physiol (1986) 0.94
Neurotensin: discovery, isolation, characterization, synthesis and possible physiological roles. Ann N Y Acad Sci (1982) 0.93
Endogenous substance P mediates cold water stress-induced increase in interleukin-6 secretion from peritoneal macrophages. J Neurosci (1996) 0.92
Effect of CP-96,345, a nonpeptide substance P receptor antagonist, on salivation in rats. Proc Natl Acad Sci U S A (1991) 0.92
Substance P. Vitam Horm (1977) 0.91
Characterization of neurotensin production by a line of rat medullary thyroid carcinoma cells. Proc Natl Acad Sci U S A (1980) 0.91
Widespread expression in adult rat forebrain of mRNA encoding high-affinity neurotensin receptor. J Comp Neurol (1998) 0.90
Avian pancreatic polypeptide phase shifts hamster circadian rhythms when microinjected into the suprachiasmatic region. Science (1984) 0.90
Multiple actions of substance P that regulate the functional properties of acetylcholine receptors of clonal rat PC12 cells. J Physiol (1987) 0.89
Substance P enhances the secretion of tumor necrosis factor-alpha from neuroglial cells stimulated with lipopolysaccharide. J Immunol (1994) 0.89
Neurotensin neurons in the rat hypothalamus: an immunocytochemical study. Endocrinology (1980) 0.88
The common C-terminal sequences of substance P and neurokinin A contact the same region of the NK-1 receptor. FEBS Lett (2000) 0.88
A neurotensin antagonist, SR 48692, inhibits colonic responses to immobilization stress in rats. Proc Natl Acad Sci U S A (1996) 0.88
Substance P sulfoxide: separation from substance P by high-pressure liquid chromatography, biological and immunological activities, and chemical reduction. Anal Biochem (1980) 0.88
The peptide binding site of the substance P (NK-1) receptor localized by a photoreactive analogue of substance P: presence of a disulfide bond. Proc Natl Acad Sci U S A (1996) 0.88
A possible neurotransmitter role for CGRP in a hair-cell sensory organ. Brain Res (1987) 0.88
Identification of methionine as the site of covalent attachment of a p-benzoyl-phenylalanine-containing analogue of substance P on the substance P (NK-1) receptor. J Biol Chem (1996) 0.87
Neurotensin in plasma: immunochemical and chromatographic character of acid/acetone-soluble material. Endocrinology (1980) 0.87
Elevation of plasma neurotensin during lipid perfusion of rat small intestine. Peptides (1981) 0.87
Identification of the site in the substance P (NK-1) receptor for modulation of peptide binding by sulfhydryl reagents. J Biol Chem (1996) 0.86
Elevation of plasma neurotensinlike immunoreactivity after a meal. Characterization of the elevated components. J Clin Invest (1982) 0.86
Evidence for substance P in the habenulo-interpeduncular tract. Brain Res (1976) 0.86
Photoaffinity labeling of the human substance P (neurokinin-1) receptor with [3H2]azido-CP-96,345, a photoreactive derivative of a nonpeptide antagonist. Mol Pharmacol (1996) 0.86
Streptozotocin-induced diabetes is associated with altered expression of peptide-encoding mRNAs in rat sensory neurons. Peptides (1996) 0.85
Pancreatic zymogen granules differ markedly in protein composition. Science (1986) 0.85
Release of substance P from isolated nerve endings. Nature (1977) 0.85
Substance P and neurotensin: their roles in the regulation of anterior pituitary function. Annu Rev Physiol (1986) 0.84
Evidence that neurotensin participates in the central regulation of the preovulatory surge of luteinizing hormone in the rat. Endocrinology (1989) 0.84
Synthesis and activities of neurotensin, and its acid and amide analogs: possible natural occurrence of [Gln4]-neurotensin. Proc Natl Acad Sci U S A (1976) 0.84
Substance P and stress-induced changes in macrophages. Ann N Y Acad Sci (1995) 0.84
Localization of aromatase and 5 alpha-reductase to neuronal and non-neuronal cells in the fetal rat hypothalamus. Brain Res (1986) 0.84
The regional distribution of somatostatin, substance P and neurotensin in human brain. Brain Res (1981) 0.84
Photoaffinity labeling the substance P receptor using a derivative of substance P containing p-benzoylphenylalanine. Biochemistry (1991) 0.83
Fluorescence analysis of picoliter samples. Anal Biochem (1980) 0.83
Estrogen-inducible neurotensin immunoreactivity in the preoptic area of the female rat. J Comp Neurol (1994) 0.83
Substance P receptor. Biochemical characterization and interactions with G proteins. Ann N Y Acad Sci (1991) 0.83
Release and degradation of neurotensin during perfusion of rat small intestine with lipid. Regul Pept (1985) 0.83
Identification and characterization of the major proteins of mammalian brain synaptic vesicles. J Neurochem (1988) 0.83
Distribution of neurotensin/neuromedin N mRNA in rat forebrain: unexpected abundance in hippocampus and subiculum. Proc Natl Acad Sci U S A (1989) 0.82
Inhibition of neurotensin release by a cyclic hexapeptide analog of somatostatin. Peptides (1986) 0.82
Estrogen induces neurotensin/neuromedin N messenger ribonucleic acid in a preoptic nucleus essential for the preovulatory surge of luteinizing hormone in the rat. Endocrinology (1989) 0.82
Stimulation of luteinizing hormone release after stereotaxic microinjection of neurotensin into the medial preoptic area of rats. Neuroendocrinology (1984) 0.82
Neuroactive substances in inner ear extracts. J Neurosci (1987) 0.81
Characterization of the substance P (NK-1) receptor in tunicamycin-treated transfected cells using a photoaffinity analogue of substance P. J Neurochem (1995) 0.81
Flavin adenine dinucleotide is a major endogenous fluorophore in the inner ear. Hear Res (1993) 0.81
Localization of neurotensin immunoreactive nerve fibers in the guinea-pig heart: evidence derived by immunohistochemistry, radioimmunoassay and chromatography. Neuroscience (1982) 0.81
Desensitization to substance P-induced vasodilation in vitro is not shared by endogenous tachykinin neurokinin A. J Neurosci (1987) 0.81
Synaptic vesicles from mammalian brain: large-scale purification and physical and immunochemical characterization. J Neurochem (1988) 0.81
Substance P and neurotensin. Recent Prog Horm Res (1982) 0.81
Evidence for spatial proximity of two distinct receptor regions in the substance P (SP)*neurokinin-1 receptor (NK-1R) complex obtained by photolabeling the NK-1R with p-benzoylphenylalanine3-SP. J Biol Chem (2001) 0.81
Isolation and identification of a polypeptide in the Hsp 70 family that binds substance P. Biochem Biophys Res Commun (1990) 0.81
Nucleotides in a single mammalian ovum or preimplantation embryo. Anal Biochem (1984) 0.80
Evidence that large synaptic vesicles containing substance P and small synaptic vesicles have a surface antigen in common in rat. Neurosci Lett (1985) 0.80
Hyperglycemic effect of neurotensin, a hypothalamic peptide. Endocrinology (1976) 0.80
Further definition of the substance P (SP)/neurokinin-1 receptor complex. MET-174 is the site of photoinsertion p-benzoylphenylalanine4 SP. J Biol Chem (2000) 0.80
Genetic construction and properties of a diphtheria toxin-related substance P fusion protein: in vitro destruction of cells bearing substance P receptors. Proc Natl Acad Sci U S A (1996) 0.80
Isolation and characterization of substance P-containing dense core vesicles from rabbit optic nerve and termini. J Neurosci Res (2000) 0.80
Guanine nucleotides decrease the affinity of substance P binding to its receptor. Eur J Pharmacol (1990) 0.80
Release of immunoreactive somatostatin from hypothalamic cells in culture: inhibition by gamma-aminobutyric acid. Proc Natl Acad Sci U S A (1980) 0.80