Published in Proc Natl Acad Sci U S A on June 01, 1980
Revised American Thyroid Association guidelines for the management of medullary thyroid carcinoma. Thyroid (2015) 2.67
Cloning and sequence analysis of a cDNA encoding rat preprocholecystokinin. Proc Natl Acad Sci U S A (1984) 1.70
Neurotensin in human small cell lung carcinoma. Br J Cancer (1984) 0.90
SR48692 inhibits non-small cell lung cancer proliferation in an EGF receptor-dependent manner. Life Sci (2014) 0.83
Immunological and biochemical characterization of processing products from the neurotensin/neuromedin N precursor in the rat medullary thyroid carcinoma 6-23 cell line. Biochem J (1993) 0.78
Medullary thyroid carcinoma in female BALB/c mice. A report of 3 cases with ultrastructural, immunohistochemical, and transplantation data. Am J Pathol (1983) 0.75
Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91
The isolation of a new hypotensive peptide, neurotensin, from bovine hypothalami. J Biol Chem (1973) 3.83
Calcium-dependent release of somatostatin and neurotensin from rat brain in vitro. Nature (1978) 1.21
Isolation of human intestinal neurotensin. J Biol Chem (1980) 1.14
Transplantable calcitonin-secreting medullary carcinomas of the thyroid in the WAG-Rij rat. J Natl Cancer Inst (1974) 1.02
Immunoreactive-beta-endorphin, -adrenocorticotropin and -calcitonin in extracts of anaplastic or differentiated (rat) medullary thyroid carcinoma. Biochem Biophys Res Commun (1979) 0.93
Self-regulation of adrenocorticotropin secretion by mouse pituitary tumor cells in culture. Endocrinology (1978) 0.90
Adrenocorticotropin and calcitonin in medullary thyroid carcinoma: frequency of occurrence and localization in the same cell type by immunocytochemistry. J Clin Endocrinol Metab (1979) 0.84
Medullary thyroid carcinoma: ectopic production of peptides with ACTH-like, corticotrophin releasing factor-like and prolactin production-stimulating activities. Acta Endocrinol (Copenh) (1976) 0.84
Multiple endocrine cell types in thyroid medullary carcinoma. Evidence for calcitonin, somatostatin, ACTH, 5HT and small granule cells. Virchows Arch A Pathol Anat Histol (1978) 0.83
Guidelines for diagnosis and therapy of MEN type 1 and type 2. J Clin Endocrinol Metab (2001) 6.12
Mutations in the sulfonylurea receptor gene in familial persistent hyperinsulinemic hypoglycemia of infancy. Science (1995) 4.25
Establishment of clonal strains of rat pituitary tumor cells that secrete growth hormone. Endocrinology (1968) 4.12
The isolation of a new hypotensive peptide, neurotensin, from bovine hypothalami. J Biol Chem (1973) 3.83
Prostaglandin-stimulated bone resorption by rheumatoid synovia. A possible mechanism for bone destruction in rheumatoid arthritis. J Clin Invest (1975) 3.24
Isolation of a sialogogic peptide from bovine hypothalamic tissue and its characterization as substance P. J Biol Chem (1970) 2.49
Studies in familial (medullary) thyroid carcinoma. Recent Prog Horm Res (1972) 2.47
Enkephalin inhibits release of substance P from sensory neurons in culture and decreases action potential duration. Proc Natl Acad Sci U S A (1979) 2.47
Evidence that the bone resorption-stimulating factor produced by mouse fibrosarcoma cells is prostaglandin E 2 . A new model for the hypercalcemia of cancer. J Exp Med (1972) 2.36
Regulation of alternative polyadenylation by U1 snRNPs and SRp20. Mol Cell Biol (1998) 2.26
CP-96,345, a substance P antagonist, inhibits rat intestinal responses to Clostridium difficile toxin A but not cholera toxin. Proc Natl Acad Sci U S A (1994) 2.22
An intron enhancer recognized by splicing factors activates polyadenylation. Genes Dev (1996) 2.08
Intrathecal morphine inhibits substance P release from mammalian spinal cord in vivo. Nature (1980) 2.08
Comparison of recombinant human PTH(1-34) (LY333334) with a C-terminally substituted analog of human PTH-related protein(1-34) (RS-66271): In vitro activity and in vivo pharmacological effects in rats. J Bone Miner Res (1999) 2.05
Polypyrimidine tract-binding protein positively regulates inclusion of an alternative 3'-terminal exon. Mol Cell Biol (1999) 2.05
Thyrotropin-releasing hormone regulates the number of its own receptors in the GH3 strain of pituitary cells in culture. Biochemistry (1975) 2.04
Increased efficiency of calcium absorption during short periods of inadequate calcium intake in girls. Am J Clin Nutr (1996) 2.04
Inositol tetrakis- and pentakisphosphates in GH4 cells. J Exp Biol (1985) 2.02
Production of both prolactin and growth hormone by clonal strains of rat pituitary tumor cells. Differential effects of hydrocortisone and tissue extracts. J Cell Biol (1970) 2.00
Amino-acid sequence of substance P. Nat New Biol (1971) 1.96
C-cell hyperplasia preceding medullary thyroid carcinoma. N Engl J Med (1973) 1.95
Clonal strains of hormone-producing pituitary cells. Methods Enzymol (1979) 1.93
Establishment of four functional, clonal strains of animal cells in culture. Science (1966) 1.90
Multiple calcium channels mediate neurotransmitter release from peripheral neurons. Proc Natl Acad Sci U S A (1986) 1.85
Hydrocortisone inhibits prostaglandin production by mouse fibrosarcoma cells. Nature (1975) 1.82
Calcitriol: the major humoral mediator of hypercalcemia in Hodgkin's disease and non-Hodgkin's lymphomas. Blood (1993) 1.80
Characterization of radioimmunoassayable neurotensin in the rat. Its differential distribution in the central nervous system, small intestine, and stomach. J Biol Chem (1976) 1.79
Alpha and beta human transforming growth factors stimulate prostaglandin production and bone resorption in cultured mouse calvaria. Proc Natl Acad Sci U S A (1985) 1.75
Calcitriol production in hypercalcemic and normocalcemic patients with non-Hodgkin lymphoma. Ann Intern Med (1994) 1.75
Adrenal cortical carcinoma. World J Surg (2001) 1.74
Increased substance P responses in dorsal root ganglia and intestinal macrophages during Clostridium difficile toxin A enteritis in rats. Proc Natl Acad Sci U S A (1997) 1.70
An intron enhancer containing a 5' splice site sequence in the human calcitonin/calcitonin gene-related peptide gene. Mol Cell Biol (1995) 1.67
Early diagnosis of medullary carcinoma of the thyroid gland by means of calcitonin assay. N Engl J Med (1971) 1.65
Substance P as a transmitter candidate. Annu Rev Neurosci (1980) 1.64
Thyrotropin-releasing hormone increases prolactin mRNA activity in the cytoplasm of GH-cells as measured by translation in a wheat germ cell-free system. Biochem Biophys Res Commun (1976) 1.62
Hypercalcemia and tumor-prostaglandins: the VX2 carcinoma model in the rabbit. Metabolism (1975) 1.60
Prostaglandin production by mouse fibrosarcoma cells in culture: inhibition by indomethacin and aspirin. Biochem Biophys Res Commun (1972) 1.60
Nonfunctioning islet cell carcinoma of the pancreas: survival results in a contemporary series of 163 patients. Surgery (2001) 1.60
Detection of medullary thyroid cancer by calcitonin assay in families. Ann Intern Med (1973) 1.56
Epidermal growth factor and thyrotropin-releasing hormone act similarly on a clonal pituitary cell strain. Modulation of hormone production and inhbition of cell proliferation. J Cell Biol (1980) 1.52
The amino acid sequence of a hypothalamic peptide, neurotensin. J Biol Chem (1975) 1.49
Pseudohypoparathyroidism: assays of parathyroid hormone and thyrocalcitonin. Proc Natl Acad Sci U S A (1966) 1.47
Thyrotropin releasing hormone: direct evidence for stimulation of prolactin production by pituitary cells in culture. Biochem Biophys Res Commun (1971) 1.44
Thyrotropin-releasing hormone-induced spike and plateau in cytosolic free Ca2+ concentrations in pituitary cells. Relation to prolactin release. J Biol Chem (1984) 1.44
Establishment of a clonal strain of hepatoma cells which secrete albumin. J Cell Biol (1969) 1.43
Epidermal growth factor stimulates prostaglandin production and bone resorption in cultured mouse calvaria. Biochem Biophys Res Commun (1978) 1.41
Medullary carcinoma of the thyroid gland. Studies of thyrocalcitonin in plasma and tumor extracts. N Engl J Med (1968) 1.38
Synthesis of the ninth component of complement by a clonal strain of rat hepatoma cells. J Immunol (1970) 1.38
Human osteopetrosis: a histological, ultrastructural, and biochemical study. J Bone Joint Surg Am (1980) 1.37
Age-resolving osteopetrosis: a rat model implicating microphthalmia and the related transcription factor TFE3. J Exp Med (1998) 1.35
Receptors for thyrotropin-releasing hormone in prolactin producing rat pituitary cells in culture. J Biol Chem (1973) 1.35
Ultrastructural localization of substance P in neurons of rat spinal cord. Brain Res (1977) 1.34
Prostaglandins, calcium metabolism and cancer. Fed Proc (1974) 1.33
Intrathecal capsaicin depletes substance P in the rat spinal cord and produces prolonged thermal analgesia. Science (1979) 1.33
Immunoreactive substance P in sympathetic ganglia: distribution and sensitivity towards capsaicin. Neuroscience (1981) 1.32
Identification of exon sequences and an exon binding protein involved in alternative RNA splicing of calcitonin/CGRP. Nucleic Acids Res (1992) 1.31
Evidence for parathyroid hormone in nonparathyroid tumors associated with hypercalcemia. Cancer Res (1965) 1.30
Control of growth hormone production by a clonal strain of rat pituitary cells. Stimulation by hydrocortisone. J Cell Biol (1969) 1.28
Arthritic calcitonin/alpha calcitonin gene-related peptide knockout mice have reduced nociceptive hypersensitivity. Pain (2001) 1.27
Production of a low molecular weight eosinophil polymorphonuclear leukocyte chemotactic factor by anaplastic squamous cell carcinomas of human lung. J Clin Invest (1978) 1.26
Single-dose intravenous therapy with pamidronate for the treatment of hypercalcemia of malignancy: comparison of 30-, 60-, and 90-mg dosages. Am J Med (1993) 1.23
Distribution of calcitonin-containing cells in the normal neonatal human thyroid gland: a correlation of morphology with peptide content. J Clin Endocrinol Metab (1975) 1.23
Role of prostaglandins in the production of hypercalcemia by tumors. Cancer Res (1978) 1.23
Regional distribution of substance P in the brain of the rat. Brain Res (1976) 1.23
Relationship of thyrotropin-releasing hormone-induced spike and plateau phases in cytosolic free Ca2+ concentrations to hormone secretion. Selective blockade using ionomycin and nifedipine. J Biol Chem (1984) 1.22
Direct sequencing of PCR products in agarose gel slices. Nucleic Acids Res (1994) 1.22
Risk estimation and screening in families of patients with medullary thyroid carcinoma. Lancet (1988) 1.21
Substance P receptor expression in intestinal epithelium in clostridium difficile toxin A enteritis in rats. Am J Physiol (1998) 1.21
The origin, distribution and synaptic relationships of substance P axons in rat spinal cord. J Comp Neurol (1979) 1.21
Tumor necrosis factor-alpha (cachectin) stimulates bone resorption in mouse calvaria via a prostaglandin-mediated mechanism. Endocrinology (1987) 1.20
Calcitonin-secreting cells of the thyroid express an extracellular calcium receptor gene. Endocrinology (1995) 1.20
Ionomycin acts as an ionophore to release TRH-regulated Ca2+ stores from GH4C1 cells. Am J Physiol (1986) 1.19
Neurotensin stimulates exocytotic histamine secretion from rat mast cells and elevates plasma histamine levels. J Physiol (1982) 1.19
Subunits of human chorionic gonadotropin: unbalanced synthesis and secretion by clonal cell strains derived from a bronchogenic carcinoma. Proc Natl Acad Sci U S A (1973) 1.19
Distribution of calcitonin-containing cells in the normal adult human thyroid gland: a correlation of morphology with peptide content. J Clin Endocrinol Metab (1974) 1.18
A substance P (neurokinin-1) receptor mutant carboxyl-terminally truncated to resemble a naturally occurring receptor isoform displays enhanced responsiveness and resistance to desensitization. Proc Natl Acad Sci U S A (1997) 1.18
Genotype-phenotype correlation in multiple endocrine neoplasia type 2: report of the International RET Mutation Consortium. J Intern Med (1995) 1.17
Differential effects of capsaicin on the content of somatostatin, substance P, and neurotensin in the nervous system of the rat. Naunyn Schmiedebergs Arch Pharmacol (1981) 1.17
Natural history of familial medullary thyroid carcinoma: effect of a program for early diagnosis. N Engl J Med (1978) 1.17
Pathogenesis of hypocalcemia in primary hypomagnesemia: normal end-organ responsiveness to parathyroid hormone, impaired parathyroid gland function. J Clin Invest (1973) 1.16
Regulation of prolactin mRNA by 1,25-dihydroxyvitamin D3 in GH4C1 cells. J Biol Chem (1983) 1.15
Radioimmunoassay for neurotensin, a hypothalamic peptide. J Biol Chem (1976) 1.15
Relevance of RET proto-oncogene mutations in sporadic medullary thyroid carcinoma. J Clin Endocrinol Metab (1996) 1.15
Isolation of human intestinal neurotensin. J Biol Chem (1980) 1.14
Platelet-derived growth factor stimulates bone resorption via a prostaglandin-mediated mechanism. Endocrinology (1982) 1.14
The clinical outcome of prospective screening for multiple endocrine neoplasia type 2a. An 18-year experience. N Engl J Med (1988) 1.13
Cortical-sparing adrenalectomy for patients with bilateral pheochromocytoma. Surgery (1996) 1.13
Biochemical characterization of two different forms of the substance P receptor in rat submaxillary gland. J Neurochem (1993) 1.13
The syndrome of excessive thyrocalcitonin produced by medullary carcinoma of the thyroid. Proc Natl Acad Sci U S A (1968) 1.12
A substance P antagonist, RP-67,580, ameliorates a mouse meningoencephalitic response to Trypanosoma brucei brucei. Proc Natl Acad Sci U S A (1997) 1.10
Nonfunctioning islet cell carcinoma of the pancreas. Surgery (1993) 1.10
Induction of prolactin synthesis in rat pituitary tumor cells by 5-bromodeoxyuridine. Cell (1977) 1.10
Enhanced expression of vascular endothelial growth factor in human SaOS-2 osteoblast-like cells and murine osteoblasts induced by insulin-like growth factor I. Endocrinology (1996) 1.10
Thyrotropin-releasing hormone induces redistribution of protein kinase C in GH4C1 rat pituitary cells. J Biol Chem (1985) 1.09
Isolation of a tridecapeptide from bovine intestinal tissue and its partial characterization as neurotensin. J Biol Chem (1976) 1.09
Immunohistochemical localization of neurotensin in endocrine cells of the gut. Cell Tissue Res (1977) 1.09