Published in Ann N Y Acad Sci on June 20, 1972
Two improved methods for preparing ferritin-protein conjugates for electron microscopy. J Cell Biol (1975) 3.81
Lectin binding and perturbation of the outer surface of the cell membrane induces a transmembrane organizational alteration at the inner surface. Proc Natl Acad Sci U S A (1974) 1.30
The fluid mosaic model of the structure of cell membranes. Science (1972) 37.43
Biological membranes as bilayer couples. A molecular mechanism of drug-erythrocyte interactions. Proc Natl Acad Sci U S A (1974) 7.95
The molecular organization of membranes. Annu Rev Biochem (1974) 7.13
Visualization by fluorescence of the binding and internalization of epidermal growth factor in human carcinoma cells A-431. Proc Natl Acad Sci U S A (1978) 5.91
Vinculin: a cytoskeletal target of the transforming protein of Rous sarcoma virus. Cell (1981) 5.74
Transmembrane control of the receptors on normal and tumor cells. I. Cytoplasmic influence over surface components. Biochim Biophys Acta (1976) 5.63
The interactions of lectins with animal cell surfaces. Int Rev Cytol (1974) 5.02
Vinculin, an intracellular protein localized at specialized sites where microfilament bundles terminate at cell membranes. Proc Natl Acad Sci U S A (1980) 4.90
Improved procedures for immunoferritin labeling of ultrathin frozen sections. J Cell Biol (1976) 4.58
Filamin, a new high-molecular-weight protein found in smooth muscle and non-muscle cells. Proc Natl Acad Sci U S A (1975) 4.38
Antibody-induced linkages of plasma membrane proteins to intracellular actomyosin-containing filaments in cultured fibroblasts. Proc Natl Acad Sci U S A (1977) 4.23
Polarization of the Golgi apparatus and the microtubule-organizing center in cultured fibroblasts at the edge of an experimental wound. Proc Natl Acad Sci U S A (1982) 4.17
Immunoelectron microscope studies of membrane-microfilament interactions: distributions of alpha-actinin, tropomyosin, and vinculin in intestinal epithelial brush border and chicken gizzard smooth muscle cells. J Cell Biol (1981) 4.15
Transmembrane interactions and the mechanism of capping of surface receptors by their specific ligands. Proc Natl Acad Sci U S A (1977) 4.04
Passage of an integral membrane protein, the vesicular stomatitis virus glycoprotein, through the Golgi apparatus en route to the plasma membrane. Proc Natl Acad Sci U S A (1981) 3.95
The interaction of Ricinus communis agglutinin with normal and tumor cell surfaces. Biochim Biophys Acta (1972) 3.94
Immunoelectron microscopic studies of the sites of cell-substratum and cell-cell contacts in cultured fibroblasts. J Cell Biol (1982) 3.92
Ferritin-conjugated plant agglutinins as specific saccharide stains for electron microscopy: application to saccharides bound to cell membranes. Proc Natl Acad Sci U S A (1971) 3.90
Anionic sites of human erythrocyte membranes. II. Antispectrin-induced transmembrane aggregation of the binding sites for positively charged colloidal particles. J Cell Biol (1973) 3.76
Phosphotyrosine-containing proteins are concentrated in focal adhesions and intercellular junctions in normal cells. Proc Natl Acad Sci U S A (1985) 3.76
Intracellular distributions of mechanochemical proteins in cultured fibroblasts. Proc Natl Acad Sci U S A (1977) 3.63
Associations of elements of the Golgi apparatus with microtubules. J Cell Biol (1984) 3.42
Reversion from transformed to normal phenotype by inhibition of protein synthesis in rat kidney cells infected with a temperature-sensitive mutant of Rous sarcoma virus. Proc Natl Acad Sci U S A (1976) 3.38
Altered distributions of the cytoskeletal proteins vinculin and alpha-actinin in cultured fibroblasts transformed by Rous sarcoma virus. Proc Natl Acad Sci U S A (1980) 3.29
The directed migration of eukaryotic cells. Annu Rev Cell Biol (1986) 3.28
Protein conformation in cell membrane preparations as studied by optical rotatory dispersion and circular dichroism. Proc Natl Acad Sci U S A (1966) 3.16
Characterization of two plant lectins from Ricinus communis and their quantitative interaction with a murine lymphoma. Biochemistry (1974) 3.13
Trans-membrane control of the receptors on normal and tumor cells. II. Surface changes associated with transformation and malignancy. Biochim Biophys Acta (1976) 2.99
Sequence and domain structure of talin. Nature (1990) 2.98
Antibody active sites and immunoglobulin molecules. Science (1966) 2.98
The localization of spectrin on the inner surface of human red blood cell membranes by ferritin-conjugated antibodies. J Cell Biol (1971) 2.96
A novel candidate metastasis-associated gene, mta1, differentially expressed in highly metastatic mammary adenocarcinoma cell lines. cDNA cloning, expression, and protein analyses. J Biol Chem (1994) 2.90
Immunocytochemical localization of alpha-actinin in intestinal epithelial cells. Proc Natl Acad Sci U S A (1979) 2.86
Polarization of the Golgi apparatus and the microtubule-organizing center within cloned natural killer cells bound to their targets. Proc Natl Acad Sci U S A (1983) 2.85
Association of mitochondria with microtubules in cultured cells. Proc Natl Acad Sci U S A (1978) 2.85
Cell biology of cytotoxic and helper T cell functions: immunofluorescence microscopic studies of single cells and cell couples. Annu Rev Immunol (1989) 2.83
Ultrastructure of chicken cardiac muscle as studied by double immunolabeling in electron microscopy. Proc Natl Acad Sci U S A (1981) 2.76
Effect of microtubule assembly status on the intracellular processing and surface expression of an integral protein of the plasma membrane. J Cell Biol (1984) 2.68
Immunoelectron microscopic studies of the intracellular transport of the membrane glycoprotein (G) of vesicular stomatitis virus in infected Chinese hamster ovary cells. J Cell Biol (1983) 2.62
Identification of a developmentally regulated protein-tyrosine kinase by using anti-phosphotyrosine antibodies to screen a cDNA expression library. Proc Natl Acad Sci U S A (1989) 2.60
The participation of alpha-actinin in the capping of cell membrane components. Cell (1979) 2.58
Temperature-dependent mobility of concanavalin A sites on tumour cell surfaces. Nat New Biol (1973) 2.56
On the mechanism of ATP-induced shape changes in human erythrocyte membranes. II. The role of ATP. J Cell Biol (1977) 2.54
An improved procedure for immunoelectron microscopy: ultrathin plastic embedding of immunolabeled ultrathin frozen sections. Proc Natl Acad Sci U S A (1984) 2.50
Membrane insertion at the leading edge of motile fibroblasts. Proc Natl Acad Sci U S A (1983) 2.45
Molecular biology of cellular membranes with applications to immunology. Adv Immunol (1974) 2.43
Alteration of the conformation of proteins in red blood cell membranes and in solution by fixatives used in electron microscopy. J Cell Biol (1968) 2.42
A general method for the specific staining of intracellular antigens with ferritin-antibody conjugates. Proc Natl Acad Sci U S A (1970) 2.31
Distribution of saccharide residues on membrane fragments from a myeloma-cell homogenate: its implications for membrane biogenesis. Proc Natl Acad Sci U S A (1972) 2.29
Detection and ultrastructural localization of human smooth muscle myosin-like molecules in human non-muscle cells by specific antibodies. Proc Natl Acad Sci U S A (1975) 2.29
The antibody-induced clustering and endocytosis of HLA antigens on cultured human fibroblasts. Cell (1980) 2.27
Local anesthetics affect transmembrane cytoskeletal control of mobility and distribution of cell surface receptors. Proc Natl Acad Sci U S A (1975) 2.26
Tumor cell instability, diversification, and progression to the metastatic phenotype: from oncogene to oncofetal expression. Cancer Res (1987) 2.24
Mitochondria are associated with microtubules and not with intermediate filaments in cultured fibroblasts. Proc Natl Acad Sci U S A (1982) 2.23
Iron-dextran antibody conjugates: General method for simultaneous staining of two components in high-resolution immunoelectron microscopy. Proc Natl Acad Sci U S A (1979) 2.22
On the mechanism of ATP-induced shape changes in human erythrocyte membranes. I. The role of the spectrin complex. J Cell Biol (1977) 2.20
Immunofluorescent localization of the transforming protein of Rous sarcoma virus with antibodies against a synthetic src peptide. Proc Natl Acad Sci U S A (1982) 2.18
Cancer metastasis. Organ colonization and the cell-surface properties of malignant cells. Biochim Biophys Acta (1982) 2.16
Bifunctional imidoesters as cross-linking reagents. Biochem Biophys Res Commun (1966) 2.14
Dynamic membrane-cytoskeletal interactions: specific association of integrin and talin arises in vivo after phorbol ester treatment of peripheral blood lymphocytes. Proc Natl Acad Sci U S A (1988) 2.12
Organ selectivity for implantation survival and growth of B16 melanoma variant tumor lines. J Natl Cancer Inst (1976) 2.09
Concanavalin-A-induced transmembrane linkage of concanavalin A surface receptors to intracellular myosin-containing filaments. Proc Natl Acad Sci U S A (1976) 2.09
Immunoferritin localization of intracellular antigens: the use of ultracryotomy to obtain ultrathin sections suitable for direct immunoferritin staining. Proc Natl Acad Sci U S A (1973) 2.07
Market-based reform: what to regulate and by whom. Health Aff (Millwood) (1995) 2.04
Topography of membrane concanavalin A sites modified by proteolysis. Nat New Biol (1972) 2.04
Coclustering of CD4 (L3T4) molecule with the T-cell receptor is induced by specific direct interaction of helper T cells and antigen-presenting cells. Proc Natl Acad Sci U S A (1987) 2.04
Covalent labeling of active sites. Adv Protein Chem (1967) 2.03
Specificity of arrest, survival, and growth of selected metastatic variant cell lines. Cancer Res (1978) 1.99
Talin is phosphorylated on tyrosine in chicken embryo fibroblasts transformed by Rous sarcoma virus. Proc Natl Acad Sci U S A (1986) 1.98
The specific direct interaction of helper T cells and antigen-presenting B cells. Proc Natl Acad Sci U S A (1986) 1.98
Ultrastructural localization of lectin-binding sites on the zonae pellucidae and plasma membranes of mammalian eggs. J Cell Biol (1975) 1.93
Development and biologic properties of malignant cell sublines and clones of a spontaneously metastasizing rat mammary adenocarcinoma. J Natl Cancer Inst (1982) 1.93
Identification, localization, and role of fibronectin in cultured bovine endothelial cells. Proc Natl Acad Sci U S A (1978) 1.89
On the nature of crossreactions observed with antibodies directed to defined epitopes. Proc Natl Acad Sci U S A (1982) 1.89
Interaction of filamin with f-actin in solution. Proc Natl Acad Sci U S A (1977) 1.87
Association of microtubules and intermediate filaments in chicken gizzard cells as detected by double immunofluorescence. Proc Natl Acad Sci U S A (1980) 1.87
Transmembrane linkage of fibronectin to intracellular actin-containing filaments in cultured human fibroblasts. Ann N Y Acad Sci (1978) 1.79
The specific interaction of helper T cells and antigen-presenting B cells. IV. Membrane and cytoskeletal reorganizations in the bound T cell as a function of antigen dose. J Exp Med (1989) 1.78
Aglycosylantibody. Effects of exoglycosidase treatments on autochthonous antibody survival time in the circulation. J Biol Chem (1976) 1.77
Fibronectin is not present in the focal adhesions formed between normal cultured fibroblasts and their substrata. Proc Natl Acad Sci U S A (1980) 1.76
ON DISSOCIATION AND RECOMBINATION OF HUMAN ADULT HEMOGLOBINS A, S, AND C. Proc Natl Acad Sci U S A (1958) 1.71
Relationships of the spectrin complex of human erythrocyte membranes to the actomyosins of muscle cells. Biochemistry (1976) 1.70
Overexpression of the MTA1 gene in gastrointestinal carcinomas: correlation with invasion and metastasis. Int J Cancer (1997) 1.67
Molecular changes in the membranes of mouse erythroid cells accompanying differentiation. Cell (1979) 1.66
Arrest and metastasis of blood-borne tumor cells are modified by fusion of plasma membrane vesicles from highly metastatic cells. Proc Natl Acad Sci U S A (1980) 1.65
Distributions of vimentin and desmin in developing chick myotubes in vivo. I. Immunofluorescence study. J Cell Biol (1984) 1.65
Anionic sites of human erythrocyte membranes. I. Effects of trypsin, phospholipase C, and pH on the topography of bound positively charged colloidal particles. J Cell Biol (1973) 1.65
Heparanases and tumor metastasis. J Cell Biochem (1988) 1.64
Heparan sulfate degradation: relation to tumor invasive and metastatic properties of mouse B16 melanoma sublines. Science (1983) 1.63
The reorientation of the Golgi apparatus and the microtubule-organizing center in the cytotoxic effector cell is a prerequisite in the lysis of bound target cells. J Mol Cell Immunol (1985) 1.62
Metastatic melanoma cell heparanase. Characterization of heparan sulfate degradation fragments produced by B16 melanoma endoglucuronidase. J Biol Chem (1984) 1.61
Freeze-etch localization of concanavalin A receptors to the membrane intercalated particles of human erythrocyte ghost membranes. Biochim Biophys Acta (1974) 1.61
Quantitative two-dimensional ultrastructural distribution of Rh o (D) antigenic sites on human erythrocyte membranes. Proc Natl Acad Sci U S A (1971) 1.60