Published in N Engl J Med on April 19, 1973
Exocrine pancreatic function in juvenile-onset diabetes mellitus. Gut (1976) 2.10
Guidelines for the investigation of chronic diarrhoea, 2nd edition. Gut (2003) 1.98
The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity. J Cell Biol (2001) 1.98
Chronic pancreatitis--definition, etiology, investigation and treatment. Dtsch Arztebl Int (2013) 1.82
Human pancreatic exocrine response to nutrients in health and disease. Gut (2005) 1.16
Effect of a long acting somatostatin analogue SMS 201-995 on jejunostomy effluents in patients with severe short bowel syndrome. Gut (1989) 1.15
Animal models for investigating chronic pancreatitis. Fibrogenesis Tissue Repair (2011) 1.14
Quantitative evolutionary design. J Physiol (2002) 1.13
Exocrine pancreatic function tests. Gut (1982) 1.12
The clinical significance of pancreatic steatosis. Nat Rev Gastroenterol Hepatol (2011) 1.10
Exocrine pancreatic function in children with coeliac disease before and after a gluten free diet. Gut (1991) 1.07
Pancreatic exocrine function in severe human chronic renal failure. Gut (1982) 1.04
Preliminary evaluation of a single-day tubeless test of pancreatic function. Br Med J (Clin Res Ed) (1981) 1.03
Pancreatic exocrine and endocrine function after operations for chronic pancreatitis. Ann Surg (1992) 1.02
Serum isoamylase as a test for pancreatic insufficiency. Gut (1983) 1.00
Fate of oral enzymes in pancreatic insufficiency. Gut (1993) 0.99
Impaired pancreatic polypeptide release in chronic pancreatitis with steatorrhoea. Gut (1979) 0.95
Proteomic analysis (GeLC-MS/MS) of ePFT-collected pancreatic fluid in chronic pancreatitis. J Proteome Res (2012) 0.94
Middle-preserving pancreatectomy: report of two cases and review of the literature. World J Surg Oncol (2013) 0.94
High prevalence of steatorrhea in 101 diabetic patients likely to suffer from exocrine pancreatic insufficiency according to low fecal elastase 1 concentrations: a prospective multicenter study. Dig Dis Sci (2003) 0.94
Sustained gastrointestinal activity of dendronized polymer-enzyme conjugates. Nat Chem (2013) 0.93
Pulmonary hypertension--a new manifestation of mitochondrial disease. J Inherit Metab Dis (2005) 0.91
Pancreatic extracts in the treatment of pancreatic exocrine insufficiency. Gut (1975) 0.91
Diagnosis and treatment of pancreatic exocrine insufficiency. World J Gastroenterol (2013) 0.90
Exocrine pancreatic insufficiency in adults: a shared position statement of the Italian Association for the Study of the Pancreas. World J Gastroenterol (2013) 0.88
Diagnostic role of gastrointestinal hormones in patients with chronic pancreatitis. Ann Surg (1986) 0.88
Postprandial gastric function in pancreatic insufficiency. Gut (1979) 0.87
Duodenal calcium outputs in health and pancreatic disease. Gut (1980) 0.87
Chronic pancreatitis: maldigestion, intestinal ecology and intestinal inflammation. World J Gastroenterol (2009) 0.87
Spare capacity and phenotypic flexibility in the digestive system of a migratory bird: defining the limits of animal design. Proc Biol Sci (2014) 0.87
Short Gel, Long Gradient Liquid Chromatography Tandem Mass Spectrometry to Discover Urinary Biomarkers of Chronic Pancreatitis. Open Proteomics J (2013) 0.86
Alleles of the major histocompatibility complex play a role in the pathogenesis of pancreatic acinar atrophy in dogs. Immunogenetics (2013) 0.86
Lingual lipase in cystic fibrosis. Quantitation of enzyme activity in the upper small intestine of patients with exocrine pancreatic insufficiency. J Clin Invest (1984) 0.85
What are the useful biological and functional markers of early-stage chronic pancreatitis? J Gastroenterol (2007) 0.85
Delayed release pancrelipase for treatment of pancreatic exocrine insufficiency associated with chronic pancreatitis. Ther Clin Risk Manag (2009) 0.84
Influence of clinical parameters on the results of 13C-octanoic acid breath tests: examination of different mathematical models in a large patient cohort. Neurogastroenterol Motil (2009) 0.83
Congenital short pancreas: a report of two cases. Gut (1985) 0.83
Chronic pancreatitis. Curr Opin Gastroenterol (2012) 0.83
Linkage analysis and gene expression profile of pancreatic acinar atrophy in the German Shepherd Dog. Mamm Genome (2005) 0.83
Pathophysiological responses to meals in the Zollinger-Ellison syndrome: 2. Gastric emptying and its effect on duodenal function. Gut (1980) 0.82
Rationale of modern dietary recommendations in cystic fibrosis. J R Soc Med (1987) 0.82
Small intestinal manifestations of diabetes mellitus. Yale J Biol Med (1984) 0.82
Exocrine pancreatic insufficiency: accuracy and clinical value of the uniformly labelled 13C-Hiolein breath test. Gut (1996) 0.82
Chronic pancreatitis: A diagnostic dilemma. World J Gastroenterol (2016) 0.81
Nutritional management of the infant with cystic fibrosis. Arch Dis Child (1995) 0.81
13C labelled cholesteryl octanoate breath test for assessing pancreatic exocrine insufficiency. Gut (1998) 0.80
13C-egg white breath test: a non-invasive test of pancreatic trypsin activity in the small intestine. Gut (2000) 0.80
Loss of cftr function leads to pancreatic destruction in larval zebrafish. Dev Biol (2015) 0.79
The role of malabsorption in bariatric surgery. World J Surg (2009) 0.78
Inhibition of postprandial pancreatic and biliary secretion by loperamide in patients with short bowel syndrome. Gut (1982) 0.78
Carbohydrate digestion and release of pancreatic polypeptide in health and diabetes mellitus. Gut (1989) 0.78
Fecal elastase: a useful test for pancreatic insufficiency? Dig Dis Sci (2010) 0.78
Uses and abuses of enzyme therapy in cystic fibrosis. J R Soc Med (1998) 0.78
Mechanisms of lipid malabsorption in Cystic Fibrosis: the impact of essential fatty acids deficiency. Nutr Metab (Lond) (2005) 0.78
Delayed release pancrelipase for the treatment of pancreatic exocrine insufficiency associated with cystic fibrosis. Ther Clin Risk Manag (2008) 0.78
Gastric emptying of liquids and postprandial pancreatobiliary secretion are temporarily impaired during endotoxemia. Dig Dis Sci (1999) 0.78
Pancrelipase: an evidence-based review of its use for treating pancreatic exocrine insufficiency. Core Evid (2012) 0.78
Pancreatic enzyme therapy. Dtsch Arztebl Int (2010) 0.78
Normal and abnormal intestinal absorption by humans. Environ Health Perspect (1979) 0.78
Complications of Chronic Pancreatitis. Dig Dis Sci (2017) 0.77
Effect of age and diet composition on activity of pancreatic enzymes in birds. J Comp Physiol B (2012) 0.77
Prevalence of exocrine pancreatic insufficiency in women with obesity syndrome: assessment by pancreatic fecal elastase 1. ISRN Gastroenterol (2011) 0.77
Analysis of endoscopic pancreatic function test (ePFT)-collected pancreatic fluid proteins precipitated via ultracentrifugation. JOP (2013) 0.77
Potential for Screening for Pancreatic Exocrine Insufficiency Using the Fecal Elastase-1 Test. Dig Dis Sci (2017) 0.76
The Pancreas: Causes for Malabsorption. Viszeralmedizin (2014) 0.76
Laboratory measurement of nutrition in cystic fibrosis. J R Soc Med (1987) 0.76
Chronic pancreatitis. Curr Opin Gastroenterol (2013) 0.76
An in vivo study of the effects on serum glucose, amylase and histopathology of the feline pancreatic tissue treated by focused ultrasound. PLoS One (2014) 0.76
Pancreatic enzyme replacement therapy for pancreatic exocrine insufficiency in the 21(st) century. World J Gastroenterol (2014) 0.76
Post-translational modifications of pancreatic fluid proteins collected via the endoscopic pancreatic function test (ePFT). J Proteomics (2013) 0.76
The Pathophysiology of Malabsorption. Viszeralmedizin (2014) 0.75
Practical guide to exocrine pancreatic insufficiency - Breaking the myths. BMC Med (2017) 0.75
Risk Factors for Steatorrhea in Chronic Pancreatitis: A Cohort of 2,153 Patients. Sci Rep (2016) 0.75
Chronic pancreatitis: diagnosis and management of complications. Gut (2007) 0.75
Exocrine pancreatic insufficiency and idiopathic haemochromatosis. Postgrad Med J (1984) 0.75
Treatment of pancreatic exocrine deficiency. World J Surg (2003) 0.75
Chronic pancreatitis: Multicentre prospective data collection and analysis by the Hungarian Pancreatic Study Group. PLoS One (2017) 0.75
Nutrients and cyclical interdigestive pancreatic enzyme secretion in humans. Gut (1996) 0.75
Fecal Fat Analyses in Chronic Pancreatitis Importance of Fat Ingestion before Stool Collection. PLoS One (2017) 0.75
Tests of pancreatic function. West J Med (1981) 0.75
Considerations on pancreatic exocrine function after pancreaticoduodenectomy. World J Gastrointest Oncol (2014) 0.75
A perspective on the use of tubeless pancreatic function tests in diagnosis. Gut (1998) 0.75
Correlation between blood lipid levels and chronic pancreatitis: a retrospective case-control study of 48 cases. Medicine (Baltimore) (2014) 0.75
Food intolerance in humans. West J Med (1979) 0.75
Chronic Pancreatitis: Current Status and Challenges for Prevention and Treatment. Dig Dis Sci (2017) 0.75
Pancreatic and Intestinal Function Post Roux-en-Y Gastric Bypass Surgery for Obesity. Clin Transl Gastroenterol (2017) 0.75
Efficacy of pancreatic enzyme replacement therapy in chronic pancreatitis: systematic review and meta-analysis. Gut (2016) 0.75
Risks of PEG tube placement in patients with cirrhosis-associated ascites. Clin Exp Gastroenterol (2017) 0.75
The complex of myxomas, spotty pigmentation, and endocrine overactivity. Medicine (Baltimore) (1985) 4.64
Clinical, biochemical, and histological remission of severe chronic active liver disease: a controlled study of treatments and early prognosis. Gastroenterology (1972) 4.29
Hereditary pancreatitis and the risk of pancreatic cancer. International Hereditary Pancreatitis Study Group. J Natl Cancer Inst (1997) 4.23
Percutaneous endoscopic gastrostomy. Indications, success, complications, and mortality in 314 consecutive patients. Gastroenterology (1987) 4.19
Cholesterol-lowering effects of a proprietary Chinese red-yeast-rice dietary supplement. Am J Clin Nutr (1999) 2.79
The different courses of early- and late-onset idiopathic and alcoholic chronic pancreatitis. Gastroenterology (1994) 2.68
Measurement of gastric functions during digestion of ordinary solid meals in man. Gastroenterology (1976) 2.56
Gastric adenocarcinoma and Helicobacter pylori infection. J Natl Cancer Inst (1991) 2.35
Intraductal papillary-mucinous tumors of the pancreas: clinicopathologic features, outcome, and nomenclature. Members of the Pancreas Clinic, and Pancreatic Surgeons of Mayo Clinic. Gastroenterology (1996) 2.33
A longitudinal survey of self-reported bowel habits in the United States. Dig Dis Sci (1989) 2.08
The triad of gastric leiomyosarcoma, functioning extra-adrenal paraganglioma and pulmonary chondroma. N Engl J Med (1977) 2.07
Clinical and pathologic correlation of 84 mucinous cystic neoplasms of the pancreas: can one reliably differentiate benign from malignant (or premalignant) neoplasms? Ann Surg (2000) 2.05
Triolein breath test: a sensitive and specific test for fat malabsorption. Gastroenterology (1979) 1.98
Predictors of outcome after percutaneous endoscopic gastrostomy: a community-based study. Mayo Clin Proc (1992) 1.94
Control of gastric emptying by osmolality of duodenal contents in man. Gastroenterology (1975) 1.92
Simultaneous measurements of total pancreatic, biliary, and gastric outputs in man using a perfusion technique. Gastroenterology (1970) 1.86
Occlusion of the jejunum for intestinal perfusion in man. Mayo Clin Proc (1966) 1.85
Comparative effects of antacids, cimetidine and enteric coating on the therapeutic response to oral enzymes in severe pancreatic insufficiency. N Engl J Med (1977) 1.85
Fate of orally ingested enzymes in pancreatic insufficiency. Comparison of two dosage schedules. N Engl J Med (1977) 1.84
Radioimmunoassay of conjugated cholyl bile acids in serum. Gastroenterology (1973) 1.81
Serum alpha-fetoprotein in patients with neoplasms of the gastrointestinal tract. Cancer Res (1975) 1.75
Prednisone for chronic active liver disease: dose titration, standard dose, and combination with azathioprine compared. Gut (1975) 1.72
Different gastric, pancreatic, and biliary responses to solid-liquid or homogenized meals. Dig Dis Sci (1979) 1.72
Increasing incidence of pancreatic cancer among women in Olmsted County, Minnesota, 1940 through 1988. Mayo Clin Proc (1992) 1.69
Anti-Salmonella agglutinins in chronic active liver disease. Lancet (1971) 1.67
Antibiotic prophylaxis for percutaneous endoscopic gastrostomy. A prospective, randomized, double-blind clinical trial. Ann Intern Med (1987) 1.65
Gastric motor abnormalities in diabetic and postvagotomy gastroparesis: effect of metoclopramide and bethanechol. Gastroenterology (1980) 1.65
Cigarette smoking as a risk factor for pancreatic cancer in patients with hereditary pancreatitis. JAMA (2001) 1.64
25-Hydroxyvitamin D3: evidence of an enterohepatic circulation in man. Proc Soc Exp Biol Med (1975) 1.61
Observer error and sampling variability tested in evaluation of hepatitis and cirrhosis by liver biopsy. Am J Dig Dis (1971) 1.61
Alimentary-tract ganglioneuromatosis. A major component of the syndrome of multiple endocrine neoplasia, type 2b. N Engl J Med (1976) 1.59
A prospective comparison of current diagnostic tests for pancreatic cancer. N Engl J Med (1977) 1.55
Gastric emptying and secretion of bile acids, cholesterol, and pancreatic enzymes during digestion. Duodenal perfusion studies in healthy subjects. Mayo Clin Proc (1974) 1.53
Gastric secretion and emptying after ordinary meals in duodenal ulcer. Gastroenterology (1977) 1.51
Pancreozymin bioassay in man based on pancreatic enzyme secretion: potency of specific amino acids and other digestive products. J Clin Invest (1970) 1.51
The preoperative carcinoembryonic antigen test in the diagnosis, staging, and prognosis of colorectal cancer. Cancer (1986) 1.50
Effect of long-term freezer storage, thawing, and refreezing on selected constituents of serum. Mayo Clin Proc (1989) 1.50
Relations of calcitonin and gastrin in the Zollinger-Ellison syndrome and medullary carcinoma of the thyroid. N Engl J Med (1973) 1.47
Water and electrolyte transport during maintenance of isotonicity in human jejunum and ileum. J Lab Clin Med (1967) 1.45
The effect of small amounts of alcohol on the clinical course of chronic pancreatitis. Mayo Clin Proc (2001) 1.43
Lymphocyte cytotoxicity and inhibition studied with autologous liver cells: observations in chronic active liver disease and the primary biliary cirrhosis syndrome. Gastroenterology (1976) 1.43
Initial clinical evaluation of an immunoradiometric assay for CA 19-9 using the NCI serum bank. Int J Cancer (1984) 1.42
Assessment of activity in chronic active liver disease. Serum bile acids compared with conventional tests and histology. N Engl J Med (1974) 1.42
Usefulness of serial serum carcinoembryonic antigen (CEA) determinations during anticancer therapy or long-term follow-up of gastrointestinal carcinoma. Cancer (1974) 1.40
Stress-induced gastroduodenal motor disturbances in humans: possible humoral mechanisms. Gastroenterology (1983) 1.40
Chronic active liver disease. The range of histologic lesions, their response to treatment, and evolution. Hum Pathol (1972) 1.40
Profile of gastric potential difference in man. Effects of aspirin, alcohol, bile, and endogenous acid. Gastroenterology (1970) 1.40
Ultrasonic endoscope. Lancet (1980) 1.40
Jejunal secretion of electrolytes and water in nontropical sprue. J Lab Clin Med (1969) 1.36
Impaired cholecystokinin-pancreozymin secretion, intraluminal dilution, and maldigestion of fat in sprue. Gastroenterology (1972) 1.35
Contrasting features and responses to treatment of severe chronic active liver disease with and without hepatitis BS antigen. Gut (1976) 1.35
Carcinoembryonic antigen test for recurrent colorectal carcinoma. Inadequacy for early detection. JAMA (1978) 1.35
Islet amyloid polypeptide is not a satisfactory marker for detecting pancreatic cancer. Gastroenterology (2001) 1.35
Postprandial gastric, pancreatic, and biliary response to histamine H2-receptor antagonists active duodenal ulcer. Gastroenterology (1977) 1.34
Disturbances in fat digestion induced by acidic jejunal pH due to gastric hypersecretion in man. Gastroenterology (1970) 1.33
Hepatic failure and the kidney. Gastroenterology (1966) 1.31
Bile acid secretion and biliary bile acid composition altered by cholecystectomy. Am J Dig Dis (1973) 1.30
Two types of leptin-responsive gastric vagal afferent terminals: an in vitro single-unit study in rats. Am J Physiol (1997) 1.30
Not 'indifference to pain' but varieties of hereditary sensory and autonomic neuropathy. Brain (1983) 1.29
Cimetidine suppression of nocturnal gastric secretion in active duodenal ulcer. N Engl J Med (1976) 1.29
NIH conference. Somatostatin and somatostatin analogue (SMS 201-995) in treatment of hormone-secreting tumors of the pituitary and gastrointestinal tract and non-neoplastic diseases of the gut. Ann Intern Med (1989) 1.28
Ammonia production in the human colon. Effects of cleansing, neomycin and acetohydroxamic acid. N Engl J Med (1970) 1.28
Evidence of an age-related decrease in intestinal responsiveness to vitamin D: relationship between serum 1,25-dihydroxyvitamin D3 and intestinal vitamin D receptor concentrations in normal women. J Clin Endocrinol Metab (1992) 1.24
Prognosis of chronic pancreatitis: an international multicenter study. International Pancreatitis Study Group. Am J Gastroenterol (1994) 1.24
Altered pancreatic and biliary function after vagotomy and pyloroplasty. Gastroenterology (1974) 1.22
Measurement of gastrointestinal transmural electric potential difference in man. Gut (1970) 1.22
Toward understanding (and management) of painful chronic pancreatitis. Gastroenterology (1999) 1.20
Effects of size, time of day and sequence of meal ingestion on carbohydrate tolerance in normal subjects. Diabetologia (1983) 1.20
Behaviour of e antigen and antibody during chronic active liver disease. Relation to HB antigen-antibody system and prognosis. Lancet (1976) 1.20
Simultaneous measurement of antroduodenal motility, gastric emptying, and duodenogastric reflux in man. Gut (1979) 1.19
Gallstones, gallbladder cancer, and other gastrointestinal malignancies. An epidemiologic study in Rochester, Minnesota. Ann Intern Med (1987) 1.19
Relationships among canine interdigestive exocrine pancreatic and biliary flow, duodenal motor activity, plasma pancreatic polypeptide, and motilin. Gastroenterology (1980) 1.18
Gastric electromechanical and neurohormonal function in anorexia nervosa. Gastroenterology (1987) 1.18
Transport of urea and ammonia production in the human colon. Lancet (1971) 1.17
Medical and surgical options in the management of patients with gastrinoma. Gastroenterology (1983) 1.17
Distribution and quantitation of gut neuropeptides in normal intestine and inflammatory bowel diseases. Dig Dis Sci (1987) 1.17
Exocrine pancreatic insufficiency in celiac sprue: a cause of treatment failure. Gastroenterology (1980) 1.17
Hepatic function tests: postoperative changes with halothane or diethyl ether anesthesia. Mayo Clin Proc (1966) 1.16
Incretin effect due to increased secretion and decreased clearance of insulin in normal humans. Diabetes (1988) 1.16
The syndrome of gastric argyrophil carcinoid tumors and nonantral gastric atrophy. Ann Intern Med (1983) 1.15
Effects of decreasing intraluminal amylase activity on starch digestion and postprandial gastrointestinal function in humans. Gastroenterology (1986) 1.14
Fate of pancreatic enzymes during small intestinal aboral transit in humans. Am J Physiol (1986) 1.14
Responses to treatment can differentiate chronic active liver disease with cholangitic features from the primary biliary cirrhosis syndrome. Gastroenterology (1976) 1.13
Regulation of pancreatic and gallbladder functions by intraluminal fatty acids and bile acids in man. J Clin Invest (1976) 1.13